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第 1–500 个,共 8,991 个页面。
- 基于数字甲状腺体模的光声探头优化设计的计算机模拟研究
In-silico investigation into optimal photoacoustic probe design using a digital thyroid phantom.
- 韩国人类、动物及水源中隐孢子虫感染的流行率
The prevalence of Cryptosporidium infection in humans, animals, and water sources in Korea.
- 整合光谱效应关系、网络药理学和多组学,破译白屈菜抗慢性肾病的机制
Integrating spectrum-effect relationship, network pharmacology and multi-omics to decipher the mechanism of Cybister chinensis Motschulsky against chronic kidney disease.
- 从巨大连通分量到社区:社区层面的洞见用于在HIV-1传播网络大型聚集群中优先确定干预措施
From giant components to communities: community-level insights for prioritizing interventions within large clusters of HIV-1 transmission networks.
- 中医药干预高血压合并失眠的发病机制和治疗潜力
Pathogenesis and therapeutic potential of traditional Chinese medicine intervention in hypertension combined with insomnia.
- NT-IGFBP-4:一种用于急性心力衰竭风险预测的新型生物标志物
NT-IGFBP-4: A novel biomarker for risk prediction in acute heart failure.
- PCOS中的诊断和预后生物标志物:探索胰岛素抵抗、全身炎症和子宫内膜容受性
Diagnostic and prognostic biomarkers in PCOS: Navigating insulin resistance, systemic inflammation, and endometrial receptivity.
- 内镜下凝血酶注射治疗胃静脉曲张出血:观察性研究和试验数据的系统评价与荟萃分析
Endoscopic Thrombin Injection for Gastric Variceal Bleeding: A Systematic Review and Meta-Analysis of Observational and Trial Data.
- 患有痴呆症的medicare受益者在急诊科STEMI就诊后的居家存活天数
Days Alive at Home After Emergency Department STEMI Visits Among Medicare Beneficiaries With Dementia.
- 微卫星高度不稳定性胃癌及胃食管结合部腺癌的临床病理特征、治疗模式与结局:一项单中心回顾性分析
Clinicopathologic Features, Treatment Patterns, and Outcomes of Microsatellite Instability-High Gastric and Gastroesophageal Junction Adenocarcinoma: A Single-Institution Retrospective Analysis.
- 短节段独立侧方腰椎椎间融合术治疗退变性腰椎侧凸的再手术率及影像学结果
Reoperation rates and radiographic outcomes after short-segment standalone lateral lumbar interbody fusion for degenerative lumbar scoliosis.
- 基于数值模拟的离心式血泵叶片参数优化与性能分析研究
Research on Optimization and Performance Analysis of Centrifugal Blood Pump Blade Parameters Based on Numerical Simulation.
- 冠状动脉粥样硬化在代谢功能障碍相关脂肪性肝病各阶段中的表现:一项VCTE-CCTA研究
Coronary atherosclerosis across stages of metabolic dysfunction-associated steatotic liver disease: a VCTE-CCTA study.
- 使用具有聚类感知验证的机器学习模型预测VHH的非特异性结合
Predicting non-specific binding of VHHs using machine learning models with cluster-aware validation.
- 基于虚拟场法的异质性动脉粥样硬化动脉材料表征
Material characterization of heterogenous atherosclerotic arteries with the Virtual Fields Method.
- 动脉粥样硬化性心血管疾病中训练免疫和炎症编程的新证据
Emerging evidence of trained immunity and inflammatory programming in atherosclerotic cardiovascular disease.
- 大鼠精子化学限定冷冻保存液的开发及通过体外受精产生后代
Development of a chemically defined cryopreservation solution for rat sperm and production of offspring by in vitro fertilization.
- HMGB1在ss-dsDNA结合位点的反作用维持了鱼精蛋白-DNA共凝聚物的流动性
Counteraction of HMGB1 at ss-dsDNA junctions maintains liquidity of protamine-DNA co-condensates.
- 第二受害者现象对医护人员的影响:范围综述
Repercussions of the second victim phenomenon on health care workers: Scoping review.
- 亚胺培南/西司他丁/瑞来巴坦治疗由亚胺培南不敏感病原体引起的医院获得性/呼吸机相关性细菌性肺炎:RESTORE-IMI 2临床研究的亚组分析和分离株分子特征分析
Imipenem/cilastatin/relebactam treatment of hospital-acquired/ventilator-associated bacterial pneumonia caused by imipenem-nonsusceptible pathogens: Subgroup analysis and molecular characterization of isolates from the RESTORE-IMI 2 clinical study.
- 对稳态负荷与多病共存之间概念和分析重叠的系统综述与实证检验
A systematic review and empiric examination of the conceptual and analytic overlap between allostatic load and multimorbidity.
- 睾丸切除术前:睾丸生殖细胞肿瘤中的性腺功能——叙述性综述
Before Orchiectomy: Gonadal Function in Testicular Germ Cell Tumors-A Narrative Review.
- 秸秆还田下缓释肥与尿素配施通过优化籽粒灌浆和淀粉生物合成协同提高水稻产量和品质
Synergistic Enhancement of Rice Yield and Quality by Combined Slow-Release Fertilizer and Urea Under Straw Incorporation Through Optimized Grain Filling and Starch Biosynthesis.
- 利用OFT细胞系建立3D共培养体系及激素补充对牙鲆生殖系基因表达的影响
{"_":"Establishment of a 3D Co-Culture System Using OFT Cell Line and Effect of Hormone Supplementation on Germline Gene Expression in Olive Flounder ().","i":["Paralichthys olivaceus"]}
- {"_":"马铃薯淀粉的水热和化学改性对其作为所选黑果腺肋花楸()果实多酚化合物载体基质性能的影响。","i":["黑果腺肋花楸"]}
{"_":"Influence of Hydrothermal and Chemical Modifications of Potato Starch on Its Performance as a Carrier Matrix for Selected Polyphenolic Compound Derived from Chokeberry () Fruit.","i":["Aronia melanocarpa"]}
- 慢性肾脏病贫血的评估与管理:肾脏疾病:改善全球预后2026临床实践指南概要
Evaluation and Management of Anemia in Chronic Kidney Disease: Synopsis of the Kidney Disease: Improving Global Outcomes 2026 Clinical Practice Guideline.
- 海马Caspase-4非经典炎症小体激活与小胶质细胞-突触串扰破坏相关并驱动抑郁样行为
Hippocampal Caspase-4 non-canonical inflammasome activation is associated with microglia-synapse crosstalk disruption and drives depression-like behaviors.
- 探索帕金森病中TIMP2遗传学与脑脊液水平:神经退行性变与衰老的生物标志物
Exploring TIMP2 genetics and CSF levels in Parkinson's disease: biomarkers of neurodegeneration and ageing.
- 肝素结合蛋白对儿童败血症器官功能障碍和疾病严重程度的预测价值:一项回顾性研究
Predictive Value of Heparin-Binding Protein for Organ Dysfunction and Disease Severity in Pediatric Sepsis: A Retrospective Study.
- 20毫米切口随机皮肤活检在血管内大B细胞淋巴瘤诊断中的实用性:单中心经验
Usefulness of 20-mm incisional random skin biopsy for diagnosis of intravascular large B-cell lymphoma: a single-center experience.
- 癌症神经科学:从局部神经免疫微环境到系统性脑-体回路
Cancer Neuroscience: From Local Neuro-Immune Microenvironments to Systemic Brain-Body Circuitry.
- 糖酵解和T细胞相关基因特征预测胰腺癌的预后和治疗反应
Glycolysis and T cell-associated gene signature predicts prognosis and therapeutic responses in pancreatic cancer.
- {"_":"基线18F-FDG PET/CT代谢定量参数对壶腹腺癌患者的预后意义。","sup":["18"]}
{"_":"Prognostic significance of baseline F-FDG PET/CT metabolic quantitative parameters for ampullary adenocarcinoma patients.","sup":["18"]}
- 临床上表现为肾上腺偶发瘤的无症状嗜铬细胞瘤:生化评估的重要性
Clinically silent pheochromocytoma presenting as an adrenal incidentaloma: the importance of biochemical evaluation.
- {“_”:“患有致病性变体并伴有全身性脂肪营养不良和严重胰岛素抵抗的儿童早发性1型糖尿病:病例报告和文献综述。”,“i”:[“CTLA4”]}
{"_":"Early-onset type 1 diabetes mellitus in a child with a pathogenic variant complicated by generalized lipodystrophy and severe insulin resistance: a case report and literature review.","i":["CTLA4"]}
- 病毒入侵对睾丸的代价:慢性HIV感染影响男性生育力的分子机制洞察
Testicular toll with viral intrusion: Molecular insights into the impact of chronic HIV infection on male fertility.
- 自身免疫性脑炎中的脉络丛异常
Choroid Plexus Abnormalities in Autoimmune Encephalitis.
- 乳酸响应性糖原动态与葡萄糖限制条件下公牛精子活力和受精相关
Lactate-Responsive Glycogen Dynamics Are Associated With Bull Sperm Motility and Fertilization Under Glucose-Limited Conditions.
- 信息化健康管理结合知信行健康教育模式在高血压患者中的应用效果
Application effects of information-based health management combined with knowledge-attitude-practice health education model in hypertensive patients.
- 永久支持性住房中的无烟家庭干预:一项整群随机临床试验
Smoke-Free Home Intervention in Permanent Supportive Housing: A Cluster Randomized Clinical Trial.
- 自身免疫性脑炎及相关神经免疫疾病中小脑-脑干网络的神经免疫机制:抗体靶点、选择性易损性与转化机遇
Neuroimmune mechanisms of the cerebellum-brainstem network in autoimmune encephalitis and related neuroimmune disorders: antibody targets, selective vulnerability, and translational opportunities.
- 抗体阳性和抗体阴性自身免疫性脑炎的复发预测因素与脑萎缩:一项多中心队列研究
Relapse predictors and brain atrophy in antibody-positive and antibody-negative autoimmune encephalitis: a multicenter cohort study.
- 精浆代谢组学探索性研究及独立HPLC-UV评估在精液质量受损男性中的应用
Exploratory seminal plasma metabolomics and independent HPLC-UV evaluation in men with impaired semen quality.
- 设备测量的有无不良妊娠结局女性体力活动:来自HUNT研究的数据
Device measured physical activity among women with and without adverse pregnancy outcomes: Data from the HUNT study.
- 一例与Barth综合征相关的双心室心力衰竭儿科患者成功桥接至心脏移植:病例报告
Successful bridge to heart transplantation in a pediatric patient with biventricular heart failure associated with Barth syndrome: a case report.
- 关节镜肩关节手术后超声引导下Teres小刺间阻滞与臂丛间阻滞镇痛的比较:一项随机非劣效性临床试验
Ultrasound-Guided Infraspinatus-Teres Minor Interfascial Block versus Interscalene Brachial Plexus Block for Analgesia After Arthroscopic Shoulder Surgery: A Randomized Non-Inferiority Clinical Trial.
- [18例卵巢幼年型颗粒细胞瘤的临床病理分析]
[Clinicopathological analysis of 18 cases of ovarian juvenile granulosa cell tumor].
- 人乳头瘤病毒对精子参数的影响:综述和荟萃分析
The Effect of Human Papillomavirus on Sperm Parameters: An Umbrella Review and Meta-analysis.
- 早期和晚期结直肠癌癌症住院患者的结果和社会人口统计学因素的比较分析
Comparative analysis of outcomes and sociodemographic factors in early- and late-onset colorectal cancer hospitalizations.
- 血流限制训练对2型糖尿病患者的有效性和安全性:一项系统评价与荟萃分析
Effectiveness and safety of blood flow restriction training for patients with type 2 diabetes mellitus: a systematic review with meta analysis.
- 算法公平性是一个人机交互问题
Algorithmic fairness as a human-technology interaction problem.
- {“_”:“单细胞转录组学揭示了与胚胎发育缺陷相关的PM暴露诱导的小鼠生殖损伤。”,“sub”:[“2.5”]}
{"_":"Single-cell transcriptomics unveils PM exposure-induced mouse reproductive damage linked to embryonic developmental defects.","sub":["2.5"]}
- CAR T细胞耐药性中的髓系相关B细胞身份重塑:弥漫性大B细胞淋巴瘤的假设生成框架
Myeloid-associated B-cell identity remodeling in CAR T-cell resistance: a hypothesis-generating framework for diffuse large B-cell lymphoma.
- {"_":"花粉舌下免疫治疗对季节性过敏性鼻结膜炎伴或不伴哮喘患者的疗效和安全性:一项真实世界研究。","i":["黄花蒿"]}
{"_":"Efficacy and safety of pollen sublingual immunotherapy in patients with seasonal allergic rhinoconjunctivitis with or without comorbid asthma: A real-world study.","i":["Artemisia annua"]}
- 在人口稀少的环极地区,由救护车临床医生评估的儿童和青少年:瑞典北部的非转运及后续医疗接触情况
Children and young people assessed by ambulance clinicians in a sparsely populated circumpolar region: non-conveyance and subsequent healthcare contacts in Northern Sweden.
- 微生物衍生代谢产物GPCR在神经退行性疾病中的信号传导
Microbiota-derived metabolite-GPCR signalling in neurodegeneration.
- 浓度在估计精浆水平范围内的丙戊酸钠通过氧化应激和线粒体功能障碍在体外损害人类精子功能
Sodium valproate at concentrations bracketing estimated seminal plasma levels impairs human sperm function in vitro through oxidative stress and mitochondrial dysfunction.
- 肠脑免疫串扰在整个生命周期中的营养调节
Nutritional regulation of gut-brain immune crosstalk across the lifespan.
- 基于Kano和SERVQUAL模型的麻醉护理服务中患者尊严与隐私需求的定量分析
The Quantitative Analysis of Patients' Dignity and Privacy Needs in Anesthesia Nursing Services Based on the Kano and SERVQUAL Models.
- 亚阈值抑郁症患者身体活动水平与肠道微生物群特征之间的关联:一项横断面研究
Association between physical activity level and gut microbiota profiles in individuals with subthreshold depression: a cross-sectional study.
- 败血症中潜在的线粒体相关致病基因:一项多组学孟德尔随机化研究
Potential mitochondria-associated pathogenic genes in sepsis: a multi-omics Mendelian randomization study.
- 相对脂肪量预测患有代谢综合征的老年人的症状性膝骨性关节炎:一项纵向队列研究
Relative fat mass predicts symptomatic knee osteoarthritis in older adults with metabolic syndrome: a longitudinal cohort study.
- 水解蛋壳膜钙螯合复合物,增强抗菌活性、抗氧化防御和男性生殖稳态功能
Hydrolyzed eggshell membrane-calcium chelation complex for enhanced antimicrobial activity, antioxidant defense, and male reproductive homeostasis function.
- 超越减肥:解开Semagutide与等效热量限制对雄性和雌性大鼠生殖系统的直接影响
Beyond weight loss: Disentangling the direct effects of semaglutide vs equivalent calorie restriction on reproductive systems of male and female rats.
- 内皮化骨痂类器官驱动临界尺寸节段性长骨缺损的快速再生
Endothelialized callus organoids drive rapid regeneration of critical-size segmental long bone defects.
- 膳食硒纳米颗粒缓解了热应激诱导的大鳞毛甲生殖障碍,其中MeSeCys是一种关键的生物活性硒物种
Dietary selenium nanoparticles alleviate heat stress-induced reproductive impairment in Onychostoma macrolepis, with MeSeCys as a key bioactive selenium species.
- 硒掺杂氢氧化钙纳米颗粒抑制破骨细胞并促进骨质疏松症治疗的成骨
Selenium-Doped Calcium Hydroxide Nanoparticles Inhibit Osteoclasts and Promote Osteogenesis for Osteoporosis Treatment.
- {“_”:“CICC 22162通过重塑肠道微生物群和增强S-腺苷甲硫氨酸介导的神经免疫调节来缓解睡眠剥夺引起的认知障碍。”,“i”:[“嗜酸乳杆菌”]}
{"_":" CICC 22162 alleviates sleep deprivation-induced cognitive impairment by remodeling gut microbiota and enhancing S-adenosylmethionine-mediated neuroimmune regulation.","i":["Lactobacillus acidophilus"]}
- PEBP1调控急性青光眼中的铁死亡:利用工程化外泌体的靶向治疗
PEBP1 Regulates Ferroptosis in Acute Glaucoma: Targeted Therapy Using Engineered Exosomes.
- 有健康问题的社区居住老年人对家的意义:一项反思性主题分析
Meaning of home among community-dwelling older adults with health concerns: a reflexive thematic analysis.
- 不同针刺联合三阶梯止痛疗法治疗骨转移癌痛:基于随机对照试验的网状Meta分析
Different Acupuncture Combined With Three-Step Analgesic Therapy in the Treatment of Bone Metastatic Cancer Pain: A Network Meta-Analysis Based on Randomized Controlled Trials.
- 小鼠中T细胞介导的中间神经元靶向塑造海马重塑与癫痫
T Cell-Mediated Targeting of Interneurons in Mice Shapes Hippocampal Remodeling and Epilepsy.
- 腹腔镜胆囊切除术中的竖脊平面阻滞:切割疼痛,而不仅仅是胆囊(随机对照试验的系统综述和荟萃分析)
Erector spinae plane block in laparoscopic cholecystectomy: cutting pain, not just gallbladder (systematic review and meta-analysis of randomized controlled trials).
- 肠神经上皮单位作为肠脑轴中与神经变性相关的界面
The gut neuroepithelial unit as a neurodegeneration-relevant interface in the gut-brain axis.
- 常规体外受精和卵母细胞胞浆内单精子注射
Conventional In Vitro Fertilization and Intracytoplasmic Sperm Injection.
- 辅助生殖技术中的精子制备:传统方法和新兴技术
Sperm Preparation in ART: Traditional Methods and Emerging Technologies.
- 通过不同的化学处理和体外消化发酵,对黑啤酒类黑色素结构-活性特征变化的新见解
New insights into the changes of structure-activity characteristics from dark beer melanoidins through different chemical treatments and in vitro digestion and fermentation.
- 通过抑制坏死性凋亡来增强调节性T细胞的持久性,从而遏制自身免疫病理
Enhancing Treg persistence by inhibiting necroptosis restrains autoimmune pathology.
- 网状虹膜模式在识别巨细胞病毒相关Posner-Schlosman综合征中的诊断价值
Diagnostic utility of reticular iris pattern for identifying cytomegalovirus-associated Posner-Schlossman syndrome.
- 在抗N-甲基-D-天冬氨酸受体脑炎中,周围神经系统受累伴随中枢神经系统受累
Peripheral nervous system involvement accompanies central nervous system involvement in anti-N-methyl-D-aspartate receptor encephalitis.
- 西式饮食会加剧M1ap基因敲除小鼠的雄性不育
A Western-style diet exacerbates male infertility in M1ap knockout mice.
- 精子特异性生育因子SMZ-1/2促进秀丽隐杆线虫FB-MO生物合成和MSP丝组装
Sperm-specific fertility factors SMZ-1/2 promote FB-MO biogenesis and MSP filament assembly in C. elegans.
- {"_":"1,25-二羟维生素D联合黄芪多糖对妊娠期糖尿病大鼠模型胰岛素抵抗的治疗作用。","sub":["3"]}
{"_":"Therapeutic effects of 1,25-dihydroxyvitamin D with astragalus polysaccharide on insulin resistance in gestational diabetes mellitus rat models.","sub":["3"]}
- 急性缺血性卒中的全身免疫炎症指数、应激性高血糖率和甘油三酯葡萄糖指数:炎症-应激代谢综合视角
Systemic immune-inflammation index, stress hyperglycemia ratio and triglyceride-glucose index in acute ischemic stroke: an integrated inflammation-stress-metabolism perspective.
- 基于机器学习的预测模型用于预测胰岛素抵抗对缺血性心肌病风险的影响
Machine learning-based prediction model for predicting the impact of insulin resistance on the risk of ischemic cardiomyopathy.
- 揭示脓毒症相关急性肾损伤的免疫炎症内型:一种基于机器学习的方法
Unveiling the immuno-inflammatory endotype of sepsis-associated acute kidney injury: a machine learning-based approach.
- 锂通过调节稳态可塑性作为SNAP25脑病的治疗策略
Lithium as a therapeutic strategy for SNAP25 encephalopathies via modulation of homeostatic plasticity.
- 神经发育障碍儿童中I-PCIT的参与度与结局
I-PCIT Engagement and Outcomes in Children With Neurodevelopmental Disorders.
- AMCP市场洞察:优化针对难治性抑郁症的管理式医疗方法
AMCP Market Insights: Optimizing managed care approaches to treatment-resistant depression.
- 多组学驱动的精准医学
Multi-omics-driven precision medicine.
- 泌尿生殖道炎症状况与白细胞增多症之间的关联:一项大规模横断面研究的见解
Association between urogenital inflammation conditions and leukocytospermia: insights from a large-scale cross-sectional study.
- 桃核承气汤减轻实验性脓毒症相关性脑病的认知障碍
Taohe Chengqi Decoction Attenuates Cognitive Impairment in Experimental Sepsis-Associated Encephalopathy.
- 基于实时视觉的老年人跌倒检测系统:一项系统性综述
Real-Time Vision-Based Fall Detection Systems for the Elderly: A Systematic Review.
- 肺炎和急性肺损伤中的微生物群免疫串扰:机制、证据和治疗机会
Microbiota-Immune Crosstalk in Pneumonia and Acute Lung Injury: Mechanisms, Evidence, and Therapeutic Opportunities.
- 小鼠母体过量摄入猪油与棕榈油会导致后代出现性别特异性生殖功能障碍
Maternal Excessive Lard Versus Palm Oil Intake in Mice Drives Sex-Specific Reproductive Dysfunction in Offspring.
- 靶向气道炎症和粘液高分泌的天然产物:呼吸健康的分子机制和治疗潜力
Natural Products Targeting Airway Inflammation and Mucus Hypersecretion: Molecular Mechanisms and Therapeutic Potential for Respiratory Health.
- 共病和炎症:慢性疾病如何引发脓毒症的宿主反应
Comorbidities and Inflammation: How Chronic Diseases Prime the Host Response in Sepsis.
- 直肠癌症手术后吻合口渗漏和盆腔脓毒症的预防、识别和管理:结构化叙述综述
Prevention, Recognition, and Management of Anastomotic Leakage and Pelvic Sepsis After Rectal Cancer Surgery: A Structured Narrative Review.
- 临床医生诊断为重度抑郁症的老年妇女每日步行量较低,中高节奏步行较少:一项探索性横断面研究
Lower Daily Walking Volume and Less Walking at Intermediate and Higher Cadences in Older Women with Clinician-Diagnosed Major Depressive Disorder: An Exploratory Cross-Sectional Study.
- 一组正常精子受精受试者的精子功能和精浆生化特征之间的相互作用
Interplay Between Sperm Function and Seminal Plasma Biochemical Profile in a Group of Normozoospermic Subjects.
- BMAL1介导的昼夜节律调控卵母细胞质量与体外受精结局
BMAL1-Mediated Circadian Regulation of Oocyte Quality and IVF Outcomes.
- 人类鞘糖脂看门人UGCG的灵长类特异性调控
Primate-specific regulation of the human glycosphingolipid gatekeeper UGCG.
- 与CACNA1H和PPP2R5D突变相关的原发性醛固酮增多症伴智力残疾:病例报告及文献综述
Primary aldosteronism with intellectual disability associated with CACNA1H and PPP2R5D mutations: a case report with review of literature.
- CatSper在精子运动和受精中的作用的结构基础
The structural basis of CatSper function in sperm motility and fertilization.
- 遗传易感性如何影响房颤消融的有效性?
How does genetic susceptibility impact the effectiveness of AF ablation?
- AIE药理学使微塑料诱导的弱精子症的细胞器疗法成为可能
AIE-pharmacology-enabled organelle therapeutics for microplastic-induced asthenozoospermia.
- 在啮齿动物模型中,NMOSD样疾病患者体内发现的抗MLC1抗体介导星形胶质细胞病
Antibodies against MLC1 found in patients with NMOSD-like disease mediate astrocytopathy in rodent models.
- DCDCC蛋白在人类精子中的表达:弱精子症的潜在分子标记
DCDC2C Protein Expression in Human Spermatozoa: A Potential Molecular Marker for Asthenozoospermia.
- 后囊破裂和超声乳化装置
Posterior capsular rupture and phacoemulsification device.
- CGRP受体拮抗作用损害小胶质细胞抗炎功能:补充IL-4作为偏头痛的补偿策略
CGRP receptor antagonism impairs microglial anti-inflammatory function: IL-4 supplementation as a compensatory strategy for migraine.
- 基于深度多模态协同生存网络的透明细胞肾细胞癌生存预测
Survival prediction for clear cell renal cell carcinoma based on deep multimodal synergistic survival network.
- 槟榔相关性口腔鳞状细胞癌治疗耐药性的分子机制:慢性炎症和上皮间质转化的相互作用
Molecular mechanisms of therapeutic resistance in areca nut-associated oral squamous cell carcinoma: the interplay of chronic inflammation and epithelial-mesenchymal transition.
- 两种标准辅助LC-MS技术揭示了天然熊胆粉中的30种“未报告”化合物,增加了新的药典质量标志
Two Standards-Aided LC-MS Technologies Uncover 30 "Unreported" Compounds in Natural Bear Bile Powder to Add a New Pharmacopoeia Quality-Marker.
- TikTok和Bilibili上血糖监测信息的质量和可靠性:横断面分析
Quality and reliability of information about blood glucose monitoring on TikTok and Bilibili: A cross-sectional analysis.
- 人源化基质-胰腺导管腺癌类器官异种移植物模型中化疗诱导的CAF相关基质重塑:GP和GS的比较
Chemotherapy-induced CAF-associated stromal remodeling in a humanized stroma pancreatic ductal adenocarcinoma organoid xenograft model: a comparison between GP and GS.
- 在非洲医疗环境中实施败血症识别预警系统:安哥拉的观点
Implementing early warning systems for sepsis recognition in African healthcare settings: an Angolan perspective.
- 乳腺腺样囊性癌:20年回顾性队列研究的临床病理特征和长期结果
Adenoid Cystic Carcinoma of the Breast: Clinicopathological Features and Long-Term Outcomes from a 20-Year Retrospective Cohort.
- EXPRESS:维持性血液透析3年预后中身体成分的变化
Alterations of body composition on 3-year prognosis of maintenance hemodialysis.
- 解锁表观遗传密码:脆性X综合征智力障碍预测性生物标志物的未来前沿
Unlocking the epigenetic code: future Frontiers in predictive biomarkers for intellectual disability in fragile X syndrome.
- 基于人工智能的工具的开发和验证,利用非散瞳眼底视网膜图像检测亚临床动脉粥样硬化:Aitheroscope项目
Development and validation of an artificial intelligence-based tool to detect subclinical atheroesclerosis using non-mydriatic retinal funduscopic images: the Aitheroscope project.
- 肝移植后的神经认知恢复是由代谢产物介导的皮质网络再激活驱动的
Neurocognitive Recovery After Liver Transplantation Is Driven by Metabolite-mediated Reactivation of Cortical Networks.
- 在数字世界中保持安全的艺术:通过数字素养和在线隐私意识来应对网络欺凌的风险
The art of staying safe in the digital world: Navigating the risks of cyberbullying through digital literacy and online privacy awareness.
- 法布里病中的中枢神经系统生物标志物:机制、临床证据与转化整合
Central nervous system biomarkers in Fabry disease: Mechanisms, clinical evidence, and translational integration.
- 巴基斯坦农村地区肺结核诊断延迟的决定因素
Determinants of delayed pulmonary tuberculosis diagnosis in a rural district of Pakistan.
- 肝病学:MASLD、病毒性肝炎、胆汁淤积性肝病、门静脉高压症和肝细胞癌的新兴范式:2026年第一届巴黎国际肝病年会总结
Hepatology: Emerging Paradigms in MASLD, Viral Hepatitis, Cholestatic Liver Disease, Portal Hypertension and Hepatocellular Carcinoma: Summary of the First Annual Paris International Liver Meeting 2026.
- 建立Cereblon(CRBN)作为儿童脓毒症早期预后生物标志物的前瞻性观察性研究方案
Development of Cereblon (CRBN) as an early prognostic biomarker in Paediatric Sepsis: a Prospective Observational Study Protocol.
- 用于代谢性疾病和癌症的微生物治疗工程化的合成生物学策略
Synthetic biology strategies for engineering microbial therapeutics in metabolic diseases and cancer.
- 炎症和女性高血压的长期发病率
Inflammation and the Long-Term Incidence of Hypertension in Women.
- 整合心血管-肾脏-代谢生物标志物的临床预测模型用于老年HFpEF患者生活质量恶化与再住院复合结局
A clinical prediction model integrating cardiovascular-kidney-metabolic biomarkers for the composite outcome of quality-of-life deterioration and rehospitalization in elderly HFpEF patients.
- 糖化白蛋白指导新诊断2型糖尿病的治疗:一项随机对照试验
Glycated Albumin Guided Therapy in Newly Diagnosed Type 2 Diabetes A Randomized Controlled Trial.
- 低血压预测指数与高平均动脉压目标预防术中低血压:一项随机对照试验
Hypotension Prediction Index versus High Mean Arterial Pressure Target for Preventing Intraoperative Hypotension: A Randomized Controlled Trial.
- 慢性阻塞性肺病急性加重危重患者住院死亡率多变量预测模型的开发和内部验证
Development and Internal Validation of a Multivariable Prognostic Model for in-Hospital Mortality in Critically Ill Patients with Acute Exacerbation of COPD.
- 妊娠早期子痫前期筛查试验对有或无不孕诊断的患者妊娠结局的影响
IMPACT OF THE FIRST TRIMESTER PREECLAMPSIA SCREENING TEST ON THE OUTCOME OF PREGNANCY BETWEEN THE PATIENTS WITH OR WITHOUT THE DIAGNOSIS OF INFERTILITY.
- 心脏成纤维细胞中的ZEB2 SUMOylization通过CtBP1相关的Nr4a1抑制驱动梗死后心脏重塑
ZEB2 SUMOylation in Cardiac Fibroblast Drives Post-Infarction Cardiac Remodeling through CtBP1-Associated repression of Nr4a1.
- 膈肌增厚分数作为急诊室通气支持需求的预测因素:一项观察性初步研究
Diaphragm thickening fraction as a predictor of the need for ventilatory support in the emergency department: an observational pilot study.
- 红细胞生成性原卟啉病中的慢加急性肝衰竭:一例病例报告及文献综述
Acute on chronic liver failure in erythropoietic protoporphyria: A case report and review of the literature.
- 使用丙酰化相关基因构建预后模型,用于预测胶质瘤患者的预后
Construction of a prognostic model using lactylation-related genes for predicting the prognosis of glioma patients.
- 活动性系统性红斑狼疮中SRI-4与LLDAS达成的比较有效性及预测因素:泰它西普与贝利尤单抗的真实世界研究
Comparative effectiveness and predictors of SRI-4 and LLDAS attainment in active systemic lupus erythematosus: a real-world study of telitacicept versus belimumab.
- Triphala通过调节肠道微生物群-甘油磷脂-TLR4轴改善高尿酸血症相关肾病
Triphala ameliorates hyperuricemia-associated nephropathy by modulating the gut microbiota-glycerophospholipid-TLR4 axis.
- 在温精汤的慢性高剂量给药下,肝脏Nrf2/HO-1通路的激活介导了小鼠胆红素水平的升高和相关的可逆性神经功能障碍
Under Chronic, High-Dose Administration of Wenjing Decoction, the Activation of the Hepatic Nrf2/HO-1 Pathway Mediates Increased Bilirubin Levels and Associated Reversible Neurologic Dysfunction in Mice.
- 2型糖尿病中MASLD/MASH的风险分层:一种实用的内分泌门诊路径
Risk stratification of MASLD/MASH in type 2 diabetes: a pragmatic endocrinology outpatient pathway.
- 护理专业学生的人工智能素养和人工智能焦虑:态度和自我效能感的系列中介作用
AI literacy and AI anxiety in nursing students: the serial mediating roles of attitudes and self-efficacy.
- {“_”:“高温和低温下PM对精子活力的协同和拮抗相互作用:来自前瞻性队列研究的证据。”,“sub”:[“2.5”]}
{"_":"Synergistic and antagonistic interactions of PM with high and low temperatures on sperm motility: Evidence from a prospective cohort study.","sub":["2.5"]}
- 菊粉的生理功能及其在畜牧生产中的应用
Physiological Function of Inulin and Its Application in Livestock Production.
- 预测机械性肠梗阻中的肠缺血:C-反应蛋白白蛋白淋巴细胞指数的作用
Predicting intestinal ischemia in mechanical intestinal obstruction: the role of the C-reactive protein-albumin-lymphocyte index.
- 解读肠易激综合征的肠脑轴:便秘和腹泻主要亚型焦虑和抑郁症状的横断面分析
Decoding the gut-brain axis in irritable bowel syndrome: a cross-sectional analysis of anxiety and depression symptoms in constipation and diarrhoea predominant subtypes.
- 中国产科医生先兆子痫风险管理的知识、实践模式和指南实施:一项探索性横断面调查
Knowledge, practice patterns, and guideline implementation for pre-eclampsia risk management among obstetricians in China: an exploratory cross-sectional survey.
- 通过[177Lu]Lu-FAPI放射性核素治疗靶向耗竭活化的成纤维细胞,改善博莱霉素诱导的肺纤维化
{"_":"Targeted depletion of activated fibroblasts via [Lu]Lu-FAPI radionuclide therapy ameliorates bleomycin-induced lung fibrosis.","sup":["177"]}
- 间歇性θ爆发刺激通过重组具有神经化学和转录组学特征的重叠脑网络改善孤独症谱系障碍患者的睡眠:一项随机对照试验
Intermittent Theta Burst Stimulation Improves Sleep in Autism Spectrum Disorder by Reorganizing Overlapping Brain Networks With Neurochemical and Transcriptomic Signatures: A Randomized Controlled Trial.
- 全身氨毒性:肝性脑病脑能量危机的低估驱动因素
Systemic Ammonia Toxicity: An Underestimated Driver of Cerebral Energy Crisis in Hepatic Encephalopathy.
- 类风湿性关节炎自身免疫中的肠道微生物功能生态学和微生物衍生代谢产物
Gut Microbial Functional Ecology and Microbiota-Derived Metabolites in Rheumatoid Arthritis Autoimmunity.
- 以浅表淋巴结受累为主的弥漫性大B细胞淋巴瘤的基于多模态超声的预后模型
Multi-Modal Ultrasound-Based Prognostic Model for Diffuse Large B-Cell Lymphoma with Predominantly Superficial Lymph Node Involvement.
- 神经发育障碍中PV神经元可塑性的认知恢复
Procognitive restoration of PV neuron plasticity in neurodevelopmental disorders.
- 高危产科人群中预测先兆子痫的眼动脉多普勒指数和母体因素:一项前瞻性队列研究
Ophthalmic Artery Doppler Indices and Maternal Factors in the Prediction of Preeclampsia in a High-Risk Obstetric Population: A Prospective Cohort Study.
- 代谢应激激活的内皮STING重新连接了MASLD中的正弦免疫生态位
Metabolic stress-activated endothelial STING rewires the sinusoidal immune niche in MASLD.
- 刺激STING通路导致抑制HBV复制:对肝巨噬细胞作用的见解
Stimulation of the STING pathway leads to inhibition of HBV replication: insights into the role of hepatic macrophages.
- 复发性呼吸道乳头状瘤病中炎症和应激相关特征筛选:一项七供体单细胞再分析及外部喉鳞状细胞癌转录组背景
Inflammation- and stress-related feature screening in recurrent respiratory papillomatosis: A seven-donor single-cell reanalysis with an external laryngeal squamous cell carcinoma transcriptomic context.
- 截断RELA变体通过损害NF-κB的负反馈控制来驱动自身炎症和自身免疫
Truncating RELA variants drive autoinflammation and autoimmunity by impairing the negative feedback control of NF-κB.
- 膈肌超声对慢性阻塞性肺疾病急性加重期机械通气患者脱机结局的预测价值:系统综述和荟萃分析
Predictive value of diaphragmatic ultrasound for weaning outcomes in mechanically ventilated patients with acute exacerbation of chronic obstructive pulmonary disease: a systematic review and meta-analysis.
- 铅通过协调线粒体损伤和ER应激介导的GPX4自噬降解引发肝细胞铁下垂
Lead triggers hepatocyte ferroptosis through coordinated mitochondrial injury and ER stress-mediated autophagic degradation of GPX4.
- “临床实践中唑来膦酸盐的急性期反应:一项对1150名患者的前瞻性单中心研究。”
"Acute-phase reactions to zoledronate in clinical practice: a prospective single center study of 1,150 patients."
- 当胸痛和肌钙蛋白升高不是急性冠状动脉综合征时:非典型嗜铬细胞瘤的心血管病例报告
When chest pain and troponin elevation aren't acute coronary syndrome: a cardiovascular case report of atypical pheochromocytoma.
- 心力衰竭和肝硬化住院的城乡差异:全国住院患者样本数据库分析(2016-2022)
Rural-Urban Disparities in Heart Failure and Liver Cirrhosis Hospitalizations: A National Inpatient Sample Database Analysis (2016-2022).
- ChatGPT与现代护理中的大型语言模型
ChatGPT and Large Language Models in Contemporary Nursing.
- 青少年垂直向咬合异常中的颈屈肌表现与颅椎姿势:一项比较性横断面研究
Cervical flexor muscle performance and craniovertebral posture in adolescents with vertical occlusal anomalies: a comparative cross-sectional study.
- 仿生对齐的鳞片状纳米地形支架重新编程糖尿病牙槽窝中的再吸收主导重塑,以增强牙槽嵴的保护
Biomimetic aligned scale-like nanotopographic scaffold reprograms resorption-dominant remodeling in diabetic sockets to enhance alveolar ridge preservation.
- 一种联合锥形束计算机断层扫描与冷冻活检的多模态支气管镜方法用于诊断外周磨玻璃结节:一项初步研究
A multimodal bronchoscopic approach for diagnosing peripheral ground-glass nodules using Cone-Beam computed tomography and cryobiopsy: a preliminary study.
- 代谢功能障碍相关的脂肪性肝病、心血管和肾脏疾病:三重挑战
Metabolic Dysfunction-Associated Steatotic Liver Disease, Cardiovascular, and Kidney Disease: Triple Challenges.
- 临床环境中的唾液流量测量:荷兰共识声明
Salivary flow measurements in a clinical setting: the Dutch consensus statement.
- circZNF148通过稳定HK1来驱动葡萄糖代谢重编程以增强癌症的转移和免疫逃避
circZNF148 Drives Glucose Metabolism Reprogramming to Enhance Metastasis and Immune Evasion via HK1 Stabilization in Triple-Negative Breast Cancer.
- [关于膈肌超声在危重患者中的临床应用的专家共识(2026年版)]
[Expert consensus on the clinical application of diaphragm ultrasound in critically ill patients (2026 edition)].
- 羟基磷灰石功能化的可注射明胶-波斯语水凝胶用于仿生口腔骨再生
Injectable Gelatin-Farsi Gum Hydrogels Functionalized With Hydroxyapatite for Biomimetic Oral Bone Regeneration.
- 更年期和骨质疏松症:流行病学、病理生理学、筛查和诊断
Menopause and osteoporosis: Epidemiology, pathophysiology, screening and diagnosis.
- 口服全氟辛酸会破坏微生物群-肠道-肝脏轴,并加剧小鼠化学诱导的结肠炎的严重程度
Oral exposure to perfluorooctanoic acid disrupts the microbiota-gut-liver axis and enhances the severity of chemically induced colitis in mice.
- 第2组先天淋巴细胞激活髓鞘反应性T细胞以增强神经炎症
Group 2 innate lymphoid cells activate myelin-reactive T cells to augment neuroinflammation.
- 分离家族性地中海热和秋水仙碱的肝脏风险:对19231名患者的倾向评分匹配分析
Disentangling the hepatic risks of familial Mediterranean Fever and colchicine: A propensity score-matched analysis of 19,231 patients.
- 海湾慢性完全闭塞登记研究:不同管理策略的短期和长期结局
The Gulf Chronic Total Occlusion Registry: Short- and Long-Term Outcomes Across Management Strategies.
- 在GBA L444P突变的帕金森病中,胆固醇增强溶酶体自噬体融合,以更好地清除α-突触核蛋白
Cholesterol enhances lysosome-autophagosome fusion for better α-synuclein clearance in GBA L444P-mutated Parkinson disease.
- 单个尿酸钠沉积物对降尿酸治疗有何反应?使用双能CT模态进行系统评估
How do individual monosodium urate depositions respond to urate-lowering therapy? A systematic evaluation using the dual-energy CT modality.
- 急性心肌梗死完全血管重建患者低灌注心肌与收缩功能的关系
The Association between Hypoperfused Myocardium and Systolic Function in Patients With AMI Undergoing Complete Revascularization.
- 评估脐带血S100B蛋白浓度作为晚期胎儿生长受限中与胎儿缺氧相关的潜在生物标志物:一项前瞻性队列研究方案
Evaluating cord blood S100B protein concentration as a potential biomarker associated with fetal hypoxia in late fetal growth restriction: A prospective cohort study protocol.
- 心力衰竭患者左心室尺寸与死亡率之间的U型关联
U-Shaped Association Between Left Ventricular Dimension and Mortality in Patients With Heart Failure.
- 胆汁酸和胆汁酸相关疗法在肝硬化中的临床意义:综述
Clinical Relevance of Bile Acid and Bile Acid-Related Therapy in Liver Cirrhosis: A Review.
- 糖尿病肾病的代谢重编程和免疫代谢失调:从发病机制到精确的多靶点治疗
Metabolic Reprogramming and Immunometabolic Dysregulation in Diabetic Kidney Disease: From Pathogenesis to Precision Multi-target Therapies.
- 雷帕霉素纳米脂质体靶向mTORC1介导的自噬溶酶体和NLRP3/Caspase-1通路,抑制椎间盘髓核细胞衰老
Rapamycin-nanoliposomes target the mTORC1-mediated autophagy-lysosomal and NLRP3/Caspase-1 pathways to inhibit nucleus pulposus cell senescence in intervertebral discs.
- 糖尿病和缺血性卒中后的认知恢复:印度南部三级护理中心的一项研究
Diabetes Mellitus and Post Stroke Cognitive Recovery After Ischaemic Stroke: A Study from Tertiary Care Centre in South India.
- 腺苷2A受体驱动小胶质细胞传出性细胞增生,加速脑卒中后白质修复和功能恢复
Adenosine 2A receptor drives microglial efferocytosis to accelerate white matter repair and functional recovery after stroke.
- 使用常规临床数据对退伍军人创伤性脑损伤后癫痫的长期预测
Long-term prediction of epilepsy following traumatic brain injury among veterans using routine clinical data.
- HBeAg阴性乙型肝炎病毒感染中核苷停药与辅助聚乙二醇干扰素核苷停药的比较(NUC-B试验)
Nucleos(t)ide withdrawal vs Nucleos(t)ide withdrawal with adjuvant pegylated-interferon in HBeAg-negative hepatitis B virus infection (NUC-B Trial).
- 老年人虚弱发病的预测风险模型:方法学趋势、模型性能和临床翻译差距的范围综述
Predictive Risk Models for Frailty Onset in Older Adults: A Scoping Review of Methodological Trends, Model Performance, and Clinical Translation Gap.
- 宫内注射富血小板血浆(PRP)对体外受精(IVF)结果影响的研究:一项队列研究
Investigation of the effect of intrauterine injection of platelet-rich plasma (PRP) on the results of in vitro fertilization (IVF): A cohort study.
- TMG中的芹菜素通过靶向GSK3β/APC/β-catenin信号通路抑制结直肠肿瘤发生
Apigenin in TMG inhibits colorectal tumorigenesis by targeting GSK3β/APC/β-catenin signaling pathway.
- 数字素养如何缓冲压力并提高护士的保留率:主动社交行为的调节中介作用
How digital literacy buffers stress and boosts retention in nurses: The moderated mediating role of proactive socialization behavior.
- 三环倍半萜avermitilol合酶的发现、鉴定及其在无质粒谷氨酸棒杆菌中的异源生产
Discovery, identification of tricyclic sesquiterpene avermitilol synthase, and its heterologous production in plasmid-free Corynebacterium glutamicum.
- 大豆(G.max)和野大豆(G.soja)转录因子Gm/GsERF160在赋予耐盐性中的功能表征
Functional characterization of the transcription factors Gm/GsERF160 from G.max and G.soja in conferring salt tolerance.
- 如何测量眼动脉多普勒进行先兆子痫筛查
How to measure ophthalmic artery Doppler for pre-eclampsia screening.
- 基于智能手机的患者报告了唑来膦酸输注后急性期反应的结果和预测算法:一项多中心、前瞻性队列研究
Smartphone-based patient-reported outcome of acute phase reaction after zoledronic acid infusion and prediction algorithm: a multicenter, prospective cohort study.
- 重症监护室压力损伤的评估:一项城市医院的点患病率研究
Evaluation of Pressure Injuries in Intensive Care Units: A Point Prevalence Study in a City Hospital.
- 在3级肥胖中,胰岛素抵抗而非肝脏组织学特征,是胰岛素清除率的主要相关因素
Insulin resistance, not hepatic histological features, is the dominant correlate of insulin clearance in class 3 obesity.
- 远端与近端桡动脉入路用于诊断性脑血管造影:比较结果与学习曲线分析
Distal versus proximal radial access for diagnostic cerebral angiography: comparative outcomes and learning curve analysis.
- 不对称的足底温度降档与房颤和血栓栓塞事件有关:SmartPreventDiabeticFeet研究的观察性事后分析
Asymmetric plantar temperature downshifts are associated with atrial fibrillation and thromboembolic events: an observational post hoc analysis of the SmartPreventDiabeticFeet study.
- 吸入LTI-03治疗特发性肺纤维化:一项随机剂量递增研究
Inhaled LTI-03 for idiopathic pulmonary fibrosis: a randomized dose escalation study.
- 肺发育不全
Pulmonary Hypoplasia.
- 脑卒中康复中的心理模拟实践重组大脑连接:系统综述
Mental simulation practices in stroke rehabilitation reorganize brain connectivity: a systematic review.
- SSAS-GO:用于蛋白质功能预测的结构-序列自适应协同网络
SSAS-GO: structure-sequence adaptive synergy network for protein function prediction.
- 头颈部肿瘤中的成纤维细胞生长因子受体信号通路:分子发病机制及潜在治疗靶点
Fibroblast growth factor receptor signaling in head and neck tumors: molecular pathogenesis and potential therapeutic targets.
- 2024年苏丹卡萨拉州战争流离失所人群中急性感染性角结膜炎队列的横断面临床与流行病学概况
A cross-sectional clinical and epidemiological overview of a cohort of acute infectious keratoconjunctivitis among war-displaced populations in Kassala State, Sudan, 2024.
- 肠道微生物群和炎症性疾病:新兴见解和治疗前景。西班牙炎症性疾病网络的一份报告
Gut Microbiota and Inflammatory Diseases: Emerging Insights and Therapeutic Perspectives. A Report From the Spanish Inflammatory Diseases Network.
- 天鹅肠道菌群的宏基因组分析及芽孢杆菌的分离、鉴定与安全性评估
{"_":"Metagenomic analysis of the gut microbiota in and isolation, identification, and safety assessment of .","i":["Cygnus cygnus","Bacillus"]}
- 孕中期眼动脉多普勒对识别先兆子痫风险女性的预测价值
Predictive value of second-trimester ophthalmic artery Doppler for identifying women at risk for preeclampsia.
- 血糖控制之外:二甲双胍在预防和治疗主要眼部疾病中的多靶点作用
Beyond Glycemic Control: Metformin's Multi-Target Role in Preventing and Treating Major Ocular Pathologies.
- 冷暴露通过非寒战性发热诱导的血小板生成加重静脉闭塞
Cold exposure aggravates vein occlusion through non-shivering thermogenesis-induced thrombocytopoiesis.
- 乳内动脉在乳腺癌症血管形成中的主导作用:肿瘤诱导的动脉重塑的动态MRI研究
Dominant Role of the Internal Mammary Artery in Breast Cancer Vascularization: A Dynamic MRI Study of Tumor-Induced Arterial Remodeling.
- 年轻缺血性卒中患者的偶发性脂肪变性肝:高血管负荷和未被充分认识的预防机会的标志
Incidental steatotic liver in young patients with ischemic stroke: A marker of high vascular burden and underrecognized prevention opportunity.
- 口咽鳞状细胞癌咽后淋巴结受累的发生率:系统评价与荟萃分析
Incidence of retropharyngeal lymph node involvement in oropharyngeal squamous cell carcinoma: a systematic review and meta-analysis.
- 时空多组学揭示了转移定植过程中的肿瘤生态系统动态
Spatiotemporal multiomics uncover tumor ecosystem dynamics during metastatic colonization.
- 大湄公河次区域动物-人类界面的人畜共患被忽视热带病:老挝和柬埔寨二十年的监测
Zoonotic neglected tropical diseases at the animal-human interface in the Greater Mekong Subregion: Two decades of surveillance in Laos and Cambodia.
- {"_":"作为多种危险过敏性疾病的致病因子。","i":["烟曲霉"]}
{"_":" as a causative agent of a number of dangerous allergic diseases.","i":["Aspergillus fumigatus"]}
- IFN-α和IFN-β抑制NLRP1驱动的PANoptosis
IFN-α and IFN-β inhibit NLRP1-driven PANoptosis.
- 卵圆孔未闭患者偏头痛的抗血栓治疗:多中心、随机、主动对照、开放标签试验
Antithrombotic treatment for migraine in patients with patent foramen ovale: multicentre, randomised, active controlled, open label trial.
- 急性和慢性肝衰竭中的生态失调——从病理生理成分到治疗靶点
DYSBIOSIS IN ACUTE-ON-CHRONIC LIVER FAILURE - FROM A PATHOPHYSIOLOGICAL COMPONENT TO A THERAPEUTIC TARGET.
- UFL1-介导的ENO1 UFMylation抑制需氧糖酵解和结直肠癌癌症进展
UFL1-Mediated UFMylation of ENO1 Restrains Aerobic Glycolysis and Colorectal Cancer Progression.
- 牙髓临床推理和决策中牙科虚拟标准化患者的初步评估:面部和结构有效性
Preliminary Evaluation of a Dental Virtual Standardized Patient in Endodontic Clinical Reasoning and Decision-Making: Face and Construct Validity.
- 毛囊干细胞:新兴生理学与治疗应用
Hair Follicle Stem Cells: Emerging Physiology and Therapeutic Applications.
- 人工智能在多中心队列研究中预测肝移植后复发性自身免疫性肝炎
Artificial intelligence predicts recurrent autoimmune hepatitis after liver transplantation in a multicenter cohort study.
- 本体感觉神经肌肉促进技术改善大鼠肩袖撕裂模型中的腱骨愈合:一项与传统电针和红外疗法对比的研究
Proprioceptive neuromuscular facilitation improves tendon-bone healing in a rat model of rotator cuff tear: a comparative study with traditional electroacupuncture and infrared therapy.
- 紫珠软膏治疗Wagner 2级糖尿病足溃疡的疗效与安全性:单中心、随机、双盲、安慰剂对照试验
Efficacy and Safety of Zizhu Ointment for Wagner Grade 2 Diabetic Foot Ulcers: A Single-Center, Randomized, Double-Blind, Placebo-Controlled Trial.
- 经定位蛋白正电子发射断层扫描作为创伤性脑损伤后创伤后癫痫和行为并发症的生物标志物
Translocator protein positron emission tomography as a biomarker for posttraumatic epilepsy and behavioral comorbidities following traumatic brain injury.
- 白蛋白用于肝硬化和细菌感染患者
Albumin for people with liver cirrhosis and bacterial infections.
- 抗药物结合物在癌症乳腺癌中的毒性:从机制视角到临床管理
Toxicities of Antibody-Drug Conjugates in Breast Cancer: From Mechanistic Insights to Clinical Management.
- 用于预测气胸相关急性肾损伤的可解释机器学习框架的开发和外部验证:一项多中心回顾性研究
Development and External Validation of an Interpretable Machine Learning Framework for Predicting Pneumothorax-Associated Acute Kidney Injury: A Multicenter Retrospective Study.
- KIF4A-KIF4B Paralog作为肺腺癌的预后生物标志物
KIF4A-KIF4B Paralog as a Prognostic Biomarker in Lung Adenocarcinoma.
- 入院时的诺顿量表改善了重症监护室基于APACHE II的死亡率预测:一项对5775名患者的回顾性队列研究
The Norton Scale at Admission Improves APACHE II-Based Mortality Prediction in the Intensive Care Unit: A Retrospective Cohort Study of 5775 Patients.
- 创伤诱导凝血病的止血复苏:综合叙述性综述
Hemostatic Resuscitation in Trauma-Induced Coagulopathy: A Comprehensive Narrative Review.
- 面向内科医生的成人肝梗死:一种避免误诊、不必要引流和血管识别延迟的实用诊断和管理途径
Adult Hepatic Infarction for Internists: A Practical Diagnostic and Management Pathway to Avoid Misdiagnosis, Unnecessary Drainage, and Delayed Vascular Recognition.
- 水蛭素作为治疗与脑递送平台:从脑卒中到中枢神经系统疾病
Hirudin as a Therapeutic and Brain-Delivery Platform: From Stroke to Central Nervous System Disorders.
- 大脑衰老的多模态特征:从描述性分析到基于机器学习的整合
Multimodal Signatures of Brain Aging: From Descriptive Analyses to Machine Learning-Based Integration.
- {“_”:“通过表型和转录组学分析鉴定耐盐种质和盐响应基因。”,“i”:[“甘蓝型油菜”]}
{"_":"Identification of Salt-Tolerant Germplasm and Salt-Responsive Genes in Through Phenotypic and Transcriptomic Analyses.","i":["Brassica napus"]}
- 使用足底压力和地面反作用力的人工智能驱动步态分析的临床翻译
Clinical Translation of Artificial Intelligence-Driven Gait Analysis Using Plantar Pressure and Ground Reaction Force.
- USP15介导的FIS1去泛素化损害线粒体功能并使膀胱癌症细胞对放射疗法敏感
USP15-mediated deubiquitination of FIS1 impairs mitochondrial function and sensitizes bladder cancer cells to radiotherapy.
- 对恶性胸腔积液管理的患者和护理人员观点的定性见解:TACTIC试验中的一项嵌入式研究
Qualitative insights into patient and carer perspectives of malignant pleural effusion management: an embedded study within the TACTIC trial.
- 释放直立委陵菜的潜力:口腔溃疡口腔粘膜粘附凝胶的开发和疗效评价
{"_":"Unlocking Potential of : Development and Efficacy Evaluation of Oral Mucoadhesive Gel for Oral Ulcers.","i":["Potentilla erecta"]}
- 超越细胞凋亡:膜联蛋白A5作为糖尿病及其并发症病理生理学中的多功能调节因子
Beyond apoptosis: Annexin A5 as a multifunctional regulator in the pathophysiology of diabetes and its complications.
- 综合运动干预对失代偿性肝硬化和肌少症患者肌肉质量和功能结果的影响:系统综述
Impact of Integrated Exercise Interventions on Muscle Mass and Functional Outcomes in Patients With Decompensated Liver Cirrhosis and Sarcopenia: A Systematic Review.
- 揭穿透明质酸注射凝胶在临床实践中的神话
Debunking Myths on Hyaluronic Acid Injectable Gels in Clinical Practice.
- 八段锦与常规呼吸练习对慢性阻塞性肺疾病患者肺功能和呼吸生物标志物的生理影响
Physiological impact of Ba Duan Jin versus conventional breathing exercises on pulmonary function and respiratory biomarkers in chronic obstructive pulmonary disease.
- 睡眠障碍管理:心血管、内分泌疾病和其他特殊人群
Sleep Disorder Management: Cardiovascular, Endocrine Disorders and Other Special Populations.
- 共同设计以家庭为中心的干预措施,以支持晚期慢性病患者的家庭护理:双钻石框架指导的过程
Co-designing a family-centered intervention to support home-based caregiving in advanced chronic illness: A double diamond framework-guided process.
- 在整个妊娠期,胎儿和母体细胞对重度子痫前期的空间分辨贡献
Spatially resolved fetal and maternal cell contributions to severe preeclampsia across gestation.
- 中国蜱中无浆体、立克次体和柯萨奇相关细菌的患病率及相关因素:系统综述和荟萃分析
Prevalence and associated factors of Anaplasma, Rickettsia, and Coxiella-related bacteria in ticks in China: A systematic review and meta-analysis.
- 入院时基于Barthel指数的活动评估可预测慢性肢体缺血威胁的伤口预后
Barthel Index-Based Activity Evaluation at Admission Predicts Wound Prognosis in Chronic Limb-Threatening Ischemia.
- 重症自身免疫性脑炎的早期预测:纳入易获取的乳酸脱氢酶的模型的开发与验证
Early prediction of severe autoimmune encephalitis: development and validation of a model incorporating readily available lactate dehydrogenase.
- PD-1/PD-L1阻断作为慢性乙型肝炎功能性治愈联合策略的一部分
PD-1/PD-L1 blockade as part of combination strategies toward functional cure of chronic hepatitis B.
- 氧化还原介导的线粒体崩溃驱动ELT3细胞对芹菜素的内在凋亡信号
Redox-mediated mitochondrial collapse drives intrinsic apoptotic signaling in ELT3 cells response to apigenin.
- 胎盘3D多普勒和子宫动脉多普勒预测胎盘植入不良结局:一项回顾性队列研究
Placental 3D Doppler and uterine artery Doppler for predicting adverse outcomes in placenta accreta: a retrospective cohort study.
- 超级衰老并不是常见变异阿尔茨海默氏症风险的反面:跨遗传祖先的证据
SuperAging is not the inverse of common-variant Alzheimer's risk: evidence across genetic ancestries.
- 在医院和家庭环境中支持3期和4期压力损伤患者的多学科团队的角色、障碍和促进者:范围界定综述
Roles, Barriers and Facilitators of Multidisciplinary Teams Supporting People With Stage 3 and 4 Pressure Injuries in Hospital and Home Settings: A Scoping Review.
- N6甲基腺苷介导的PAICS上调通过整合素FAK信号传导促进肺腺癌转移
N6-methyladenosine-mediated upregulation of PAICS promotes lung-adenocarcinoma metastasis via the integrin-FAK signaling.
- 肺腺癌远处转移的机制和治疗靶点
Mechanisms and therapeutic targets in distant metastasis of lung adenocarcinoma.
- 不同牙型中副根管的垂直分布:系统评价与荟萃分析
Vertical distribution of accessory canals in different tooth types: A systematic review and meta-analysis.
- 解码转录组时钟在人类前额叶皮层中的作用
Decoding the role of transcriptomic clocks in the human prefrontal cortex.
- WNK-SPAK-NKCC1/KCC2通路破坏了原发性高血压患者的氯稳态,并促使PVN-CRH神经元过度激活
WNK-SPAK-NKCC1/KCC2 pathway disrupts chloride homeostasis and drives hyperactivation of PVN-CRH neurons in essential hypertension.
- obinutuzumab治疗特发性膜性肾病的临床疗效
Clinical effect of obinutuzumab in the treatment of idiopathic membranous nephropathy.
- 基于机器学习算法的局部晚期癌症患者新辅助治疗后的多模式特征和预后风险评估:一项多中心研究
Multimodal features and prognostic risk assessment in locally advanced gastric cancer patients following neoadjuvant therapy based on machine learning algorithms: a multicenter study.
- 促进健康老龄化的微量营养素和ω-3多不饱和脂肪酸:为基于生理学的互补策略提供信息
Micronutrients and omega-3 PUFAs to promote healthy ageing: informing a physiology-based complementation strategy.
- 轻度认知障碍老年人不同运动方式与平衡能力和皮质血流动力学反应的关系
Associations of different exercise modalities with balance performance and cortical hemodynamic responses in older adults with mild cognitive impairment.
- IL6/IL-6R介导的肺癌机制:从发病机制到潜在治疗靶点
IL-6/IL-6R-Mediated Mechanisms in Lung Cancer: From Pathogenesis to Potential Therapeutic Targets.
- MRGBMDAT:一种用于miRNA-疾病关联类型预测的多关系图编码器网络与双线性融合方法
MRGBMDAT: a multi-relational graph encoder network with bilinear fusion for miRNA-disease association type prediction.
- 地中海饮食结合体育活动对老年人认知功能的影响:范围综述
The effect of the Mediterranean diet combined with physical activity on cognitive function in older adults: a scoping review.
- 青少年相对脂肪量和近视:使用NHANES数据的横断面研究
Relative fat mass and myopia in adolescents: a cross-sectional study using NHANES data.
- 降低显性肝性脑病复发的风险:叙述性综述
Reducing the Risk of Overt Hepatic Encephalopathy Recurrence: A Narrative Review.
- 时间干扰刺激:非侵入性深部脑刺激机制见解、临床进展和未来方向的新范式
Temporal interference stimulation: A new paradigm for non-invasive deep brain stimulation-mechanistic insights, clinical advances, and future directions.
- RADS-PDD:面向大语言模型的、可感知可复现性的动态相似性预训练数据检测方法
RADS-PDD: Reproducibility-aware dynamic similarity-based pre-training data detection against LLMs.
- 九种神经系统疾病的脑衰老模式:一项病例对照研究
Brain aging patterns among nine neurological disorders: A case-control study.
- 不可切除肺淋巴上皮癌的一线治疗:含或不含PD-1抑制剂的铂类双药化疗的现实比较
First-line treatment for unresectable pulmonary lymphoepithelial carcinoma: A real-world comparison of platinum-based doublet chemotherapy with or without PD-1 inhibitors.
- 数字素养和伦理意识在护士接受人工智能中的作用:一项横断面问卷调查
The role of digital literacy and ethical awareness in nurses' acceptance of Artificial Intelligence: a cross-sectional questionnaire survey.
- 基于人工智能的心血管疾病风险预测工具的范围综述
A scoping review on artificial intelligence-based tools for cardiovascular disease risk prediction.
- 表观基因组修饰定义染色质状态以调控游离DNA片段组学
Epigenomic modifications define chromatin states to regulate cell-free DNA fragmentomics.
- 长期接触除草剂后多重抗性的演变重塑了地中海多年生农业生态系统
Evolution of multiple resistance under long-term herbicide exposure reshapes Mediterranean perennial agroecosystems.
- 亚慢性暴露于氯化镧通过AMPK依赖性脂噬缺陷诱导雄性斑马鱼肝脏脂肪变性
Sub-chronic exposure to lanthanum chloride induces hepatic steatosis via AMPK-dependent lipophagic defects in male zebrafish.
- 青少年男性新精神活性物质使用者的基于人格的亚组识别和心理症状模式:对有针对性干预的影响
Personality-based subgroup identification and psychological symptom patterns in adolescent male new psychoactive substance users: implications for targeted intervention.
- 腹部电刺激联合气道清除技术对神经系统疾病气管切开患者的影响:一项随机对照试验
Effects of Abdominal Electrical Stimulation Combined With Airway Clearance Techniques in Tracheotomized Patients With Neurological Disorders: A Randomized, Controlled Trial.
- 扶正化瘀片可降低HBV相关性肝硬化患者首次失代偿后进一步失代偿的风险:一项随机、双盲、安慰剂对照、多中心试验方案
Fuzheng Huayu tablets reduces the risk of further decompensation after the first decompensation in patients with HBV-related cirrhosis: protocol for a randomized, double-blind, placebo-controlled, multicenter trial.
- 放射性肺损伤中的肠肺轴:机制和干预措施
Gut-lung axis in radiation-induced lung injury: mechanisms and interventions.
- Lamtor5的年龄相关性下降通过cGAS介导的旁分泌炎症驱动免疫衰老和全身衰老
Age-associated decline of Lamtor5 drives immunosenescence and systemic aging via cGAS-mediated paracrine inflammation.
- Abca7相关小胶质细胞反应在连接2型糖尿病与阿尔茨海默病进展中的作用:来自单细胞转录组分析和动物及细胞模型实验验证的证据
Role of Abca7-related microglial responses in linking type 2 diabetes mellitus to Alzheimer's disease progression: Evidence from single-cell transcriptomic analysis and experimental validation in animal and cell models.
- 毛细管素是一种来自茵陈蒿的香豆素,通过靶向GSK3β/Nrf2抑制铁下垂来减轻APAP肝毒性
Capillarisin, a coumarin from Artemisia capillaris, alleviates APAP hepatotoxicity by targeting GSK3β/Nrf2 to suppress ferroptosis.
- 对生活在长期护理环境中的老年人规模下降表示担忧
Development of a concern about falling scale for older adults living in long-term care settings.
- 组织驻留巨噬细胞对衰老中性粒细胞的恢复清除限制了器官衰老
Restored clearance of senescent neutrophils by tissue-resident macrophages limits organ aging.
- 高速阻力训练改善了中老年人的力-速度曲线
High-velocity resistance training improves the force-velocity profile in middle-aged and older adults.
- 使用子宫动脉多普勒搏动指数、血流动力学和生化参数早期预测子痫前期的多标记方法:一项前瞻性观察研究
A Multimarker Approach for Early Prediction of Preeclampsia Using Uterine Artery Doppler Pulsatility Index, Hemodynamic, and Biochemical Parameters: A Prospective Observational Study.
- 体重调整后的腰围指数、炎症和老年人的认知能力:霍达伦健康研究的横断面分析
Weight-adjusted-waist index, inflammation, and cognitive performance in older adults: a cross-sectional analysis from the Hordaland Health Study.
- 自发性低颅压患者多域自主神经功能障碍的频率和特征
Frequency and characteristics of multi-domain autonomic dysfunction in patients with spontaneous intracranial hypotension.
- 骨钙素/CLEC11A在牙周炎和种植周炎中的相关信号分子
Osteolectin/CLEC11A-Related Signaling Molecules in Periodontitis and Peri-Implantitis.
- 疑似肌痛性脑脊髓炎/慢性疲劳综合征的儿童、青少年和年轻人的握力
Handgrip strength in children, adolescents, and young adults with suspected myalgic encephalomyelitis/chronic fatigue syndrome.
- 学习曲线和围手术期结果:同步和联合充气纵隔镜腹腔镜食管癌根治术的回顾性队列研究
Learning curve and perioperative outcomes: a retrospective cohort study between synchronous and combined inflatable mediastinoscope-laparoscopic radical esophagectomy.
- FGF21抑制CYP2E1-19-HETE-BLT2介导的氧化损伤扩增,缓解心肌梗死重塑
Inhibition of the CYP2E1-19-HETE-BLT2-mediated oxidative injury amplification by FGF21 alleviates myocardial infarction remodeling.
- 冰山一角:育龄妇女多囊卵巢综合征的发病率
The tip of the iceberg: morbidity in polycystic ovary syndrome in reproductive-age women.
- 多支冠状动脉疾病的扩展双重抗血小板治疗
Extended Dual Antiplatelet Therapy for Multivessel Coronary Artery Disease.
- 光周期对尼罗罗非鱼性腺发育及神经肽Y和NPY1受体的影响
Effects of photoperiod on gonadal development and neuropeptide Y and NPY1 receptor in Nile tilapia (Oreochromis niloticus).
- 系统的全癌分析揭示了WDR1在肾癌和胃癌中具有不同影响的上下文依赖性预后和免疫作用
Systematic pan-cancer analysis reveals context-dependent prognostic and immunological roles of WDR1 with divergent effects in renal and gastric cancers.
- 妊娠期糖尿病妇女的特定妊娠期体重增加和不良结局:一项回顾性队列研究
Trimester-specific gestational weight gain and adverse outcomes in GDM women: a retrospective cohort study.
- 护士对压力性损伤知识的评估:一项全国性多中心横断面研究
Assessment of Nurses' Knowledge Regarding Pressure Injury: A National Multicenter Cross-Sectional Study.
- PFAS相关血管衰老的成像和分子生物标志物:叙述性综述
Imaging and Molecular Biomarkers of PFAS-Related Vascular Aging: A Narrative Review.
- 1型糖尿病患者每月连续血糖监测衍生指标的变异性与糖尿病肾病的相关性
Association of Variability of Monthly Continuous Glucose Monitoring-Derived Metrics With Diabetic Kidney Disease in Type 1 Diabetes.
- 外源性肌酸补充通过巨核细胞肌酸激酶B-STAT5B信号传导促进肿瘤转移
Exogenous creatine supplementation promotes tumor metastasis via megakaryocyte creatine kinase B-STAT5B signaling.
- 肺泡巨噬细胞中GPX3的下调放大了ARDS中IL-17依赖的氧化还原炎症串扰
GPX3 downregulation in alveolar macrophages amplifies IL-17-dependent redox-inflammation crosstalk in ARDS.
- Grx通过激活晶状体上皮细胞中AMPK/BNIP3/BNIP3L介导的自噬来减轻糖尿病性白内障
Grx attenuates diabetes cataract by activating AMPK/BNIP3/BNIP3L-mediated mitophagy in lens epithelial cells.
- 代谢综合征与大脑加速衰老有关
Metabolic syndrome is associated with accelerated brain aging.
- 衰老机制的机制冗余和层次:对延长健康寿命和生物标志物整合策略的影响
Mechanistic redundancy and hierarchy of aging mechanisms: implications for strategies to extend healthspan and biomarker integration.
- GLP-1受体激动剂、运动及其联合干预对超重或肥胖成人身体成分和糖脂代谢的比较疗效:随机对照试验的网络荟萃分析
Comparative Efficacy of GLP-1 Receptor Agonists, Exercise, and Their Combination on Body Composition and Glucolipid Metabolism in Adults With Overweight or Obesity: A Network Meta-Analysis of Randomized Controlled Trials.
- 妊娠中期血清PlGF水平与多普勒超声异常的一致性
Agreement between Mid-pregnancy Serum Placental Growth Factor Levels and Abnormalities in Uterine Doppler Ultrasound Findings.
- 食物和花粉过敏原与MRGPRX2 D184的结合:IgE非依赖性肥大细胞活化的计算假说
MRGPRX2 D184 Engagement by Food and Pollen Allergens: A Computational Hypothesis for IgE-Independent Mast-Cell Activation.
- 远距离的笨拙动作:神经调控、生理性痛苦信号和肢体保护
Spooky action at a distance: neuromodulation, physiologic distress signals, and limb preservation.
- 冠状动脉疾病中冠状动脉微血管功能障碍的免疫代谢机制:线粒体应激、内皮衰老和调节细胞死亡的作用
Immunometabolic Mechanisms of Coronary Microvascular Dysfunction in Coronary Artery Disease: The Role of Mitochondrial Stress, Endothelial Senescence, and Regulated Cell Death.
- 衰老和神经退行性变中的核功能障碍
Nuclear dysfunction in aging and neurodegeneration.
- 检查疗养院居民压力损伤发展的危险因素:一项回顾性研究
Examining Risk Factors for Pressure Injury Development Among Nursing Home Residents: A Retrospective Study.
- 界面工程产甲烷纳米生物杂化物重定向氢通量,实现高效CO2固定
Interface-Engineered Methanogenic Nanobiohybrids Redirect Hydrogen Flux for Efficient CO2 Fixation.
- 垂体瘤转化基因1在实体瘤中的临床和预后意义
Clinical and prognostic implications of pituitary tumor-transforming gene 1 in solid tumors.
- 氧化应激介导的脑-骨轴失调的机制和疾病关联:基于文献计量学的知识图谱和趋势分析
Mechanisms and disease associations of oxidative stress-mediated brain-bone axis dysregulation: a knowledge mapping and trend analysis based on Bibliometrics.
- 对香港本氏Coxiella burnetii动物库的监测显示,本地动物(包括反刍动物、伴侣动物和啮齿类动物)Q热的人畜共患风险较低
{"_":"Surveillance for animal reservoirs in Hong Kong suggests low zoonotic risk of Q-fever from local animals including ruminants, companion animals and rodents.","i":["Coxiella burnetii"]}
- 吸入盐酸氨溴索溶液治疗中国儿童急性下呼吸道感染的有效性和安全性:一项现实世界、多中心、开放标签、单臂研究
Efficacy and safety of inhaled ambroxol hydrochloride solution in Chinese pediatric patients with acute lower respiratory tract infections: a real-world, multicenter, open-label, single-arm study.
- 使用子宫胎盘多普勒和胎盘微血管灌注指数对新生儿呼吸窘迫综合征进行产前预测:风险模型的开发
Prenatal prediction of neonatal respiratory distress syndrome using uteroplacental Doppler and placental microvascular perfusion indices: development of a risk model.
- 护理人工智能素养:概念分析
Artificial intelligence literacy in nursing: a concept analysis.
- 基于临床和动态血液学参数的肺淋巴上皮癌复发风险预测模型和复发模式
A recurrence risk prediction model and recurrence patterns in pulmonary lymphoepithelial carcinoma based on clinical and dynamic hematologic parameters.
- 糖尿病足感染的微生物和炎症特征:严重程度分层分析
Microbiological and inflammatory profiles in diabetic foot infection: A severity-stratified analysis.
- {“_”:“确定FOXK1和SEMA7A是与糖尿病视网膜病变中mA相关程序性细胞死亡相关的关键基因。”,“sup”:[“6”]}
{"_":"Identification of FOXK1 and SEMA7A as key genes associated with mA-related programmed cell death in diabetic retinopathy.","sup":["6"]}
- 癌症患者应在粪便微生物群移植加抗PD-1治疗的同时进行药物报告
Concomitant medication reporting should accompany fecal microbiota transplantation plus anti-PD-1 therapy in gastric cancer.
- 在ICU留置导尿管患者中实施预防尿漏的循证实践:JBI指导的基线综述
Implementing evidence-based practices for urinary leakage prevention in ICU patients with indwelling catheters: A JBI-guided baseline review.
- 优化血液吸附联合血液透析(HAHD)的启动过程:一项两阶段体外和临床验证研究
Optimizing the Priming Process for Hemoadsorption Combined with Hemodialysis: A Two-Stage in vitro and Clinical Validation Study.
- 脂蛋白(a)与心血管风险:对慢性肾脏病具有意义的新兴治疗前景
Lipoprotein(a) and Cardiovascular Risk: Emerging Therapeutic Perspectives with Implications for Chronic Kidney Disease.
- 探讨UFSP2在乳腺癌症主轴组装检查点调节中的潜在作用
Exploring the potential involvement of UFSP2 in spindle assembly checkpoint regulation in breast cancer.
- 核苷类似物天然产物:十多年来在分离、生物活性和合成方面的进展
Nucleoside Analog Natural Products: Over a Decade of Advances in Isolation, Biological Activity, and Synthesis.
- 新型mRNA分类器的开发用于术前甲状腺肿瘤风险分层
Development of Novel mRNA Classifiers to Stratify Preoperative Thyroid Tumor Risk.
- 化学交换饱和转移的场强依赖敏感性:临床队列中3特斯拉和7特斯拉的方法学比较
Field strength-dependent sensitivity of chemical exchange saturation transfer: a methodological comparison of 3 Tesla and 7 Tesla in a clinical cohort.
- 护理教育者的数字素养和创造性教学行为:自我效能感和数字压力的连锁中介作用
Digital literacy and creative teaching behavior among nursing educators: the chain mediating roles of self-efficacy and digital stress.
- UFSP2-ODR4复合物在空间上限制并动态控制UFM1的解偶联,以保护神经元的蛋白质稳定
The UFSP2-ODR4 complex spatially confines and dynamically controls UFM1 deconjugation to safeguard neuronal proteostasis.
- 肥胖和年龄升高组织-残余微生物Akkermansia muciniphila诱导氧化应激并增加乳腺癌症风险
Obesity and Age Elevate Tissue-Resident Microbiota Akkermansia muciniphila to Induce Oxidative Stress and Promote Breast Cancer Risk.
- {"_":"草莓的浅层驯化瓶颈:从野生种中恢复基于次生代谢物的防御能力。","i":["Fragaria"]}
{"_":"The shallow domestication bottleneck of strawberry: recovering secondary metabolite-based defenses from wild species.","i":["Fragaria"]}
- 有特殊医疗保健需求的儿童、慢性疼痛与未满足的医疗保健需求之间的关系
The Relationship Between Children with Special Health Care Needs, Chronic Pain, and Unmet Health Care Needs.
- 术中吸入麻醉与静脉麻醉对接受血运重建手术的烟雾病患者围术期神经功能结局及长期预后的影响:一项系统评价和荟萃分析
Effects of intraoperative inhalational versus intravenous anesthesia on perioperative neurological outcomes and long-term prognosis in patients with moyamoya disease undergoing revascularization surgery: a systematic review and meta-analysis.
- BET抑制在特定亚型的三阴性乳腺癌中通过HIF1α稳定化及驱动的转录程序揭示了一种可靶向的糖酵解依赖性
BET inhibition unmasks a targetable glycolytic dependency through a HIF1α stabilization and driven transcriptional program in a defined subset of triple-negative breast Cancer.
- 不伴有严重高血压的非典型子痫——眼动脉多普勒和sFlt-1/PlGF比值的作用:病例报告
Atypical eclampsia without severe hypertension - the role of ophthalmic artery Doppler and sFlt-1/PlGF ratio: a case report.
- 心理动力学运动和舞蹈治疗的全球经验模式——身体意识作为治疗因素:效果和临床考虑
The Global Mode of Experience in Psychodynamic Movement and Dance Therapy - Bodily Awareness as a Therapeutic Factor: Effects and Clinical Considerations.
- Romosozumab治疗严重绝经后骨质疏松症的真实世界数据来自192名女性
Romosozumab in severe postmenopausal osteoporosis-real-world data from 192 women.
- 青少年原发性痛经的长期管理和预防策略:从精确诊断到综合干预
Long-Term Management and Prevention Strategies for Adolescent Primary Dysmenorrhea: From Precision Diagnosis to Comprehensive Intervention.
- 四种具有代表性的发酵酒精饮料中的有机酸:吸收、代谢归宿和健康益处的分子机制
Organic acids in four representative fermented alcoholic beverages: absorption, metabolic fate, and molecular mechanisms of health benefits.
- 早期妊娠眼动脉多普勒预测早发性和早产先兆子痫:系统综述和批判性评价
First-trimester ophthalmic artery Doppler for prediction of early-onset and preterm preeclampsia: a systematic review and critical appraisal.
- 铁下垂和败血症引起的心肌损伤:一项前瞻性临床研究
Ferroptosis and sepsis-induced myocardial injury: a prospective clinical study.
- 芬太尼对膝关节置换术患者膈肌力量的影响:一项随机双盲临床试验
Effects of fentanyl on diaphragm muscle force in patients undergoing knee arthroplasty: a randomised double-blind clinical trial.
- 从糖尿病足到痴呆:连接全身性糖尿病血管病变、脑小血管疾病和淋巴功能障碍的神经血管连续体
From diabetic foot to dementia: A neurovascular continuum linking systemic diabetic vasculopathy, cerebral small vessel disease, and glymphatic dysfunction.
- 实验性心肌梗死后浸润单核细胞的命运图揭示了梗死心脏的分化轨迹
Fate-mapping infiltrating monocytes following experimental myocardial infarction reveals differentiation trajectories in the infarcted heart.
- PYRIN m6A修饰在脓毒症诱导的心肌病中驱动心肌细胞全景
{"_":"PYRIN mA modification drives cardiomyocyte PANoptosis in sepsis-induced cardiomyopathy.","sup":["6"]}
- 在大鼠模型中,食管切除吻合术后远程缺血预处理增强了血管生成和增殖作用
Enhanced angiogenetic and proliferative effects of remote ischemic conditioning following esophageal resection and anastomosis in a rat model.
- 膝骨性关节炎在线疼痛自我管理程序的开发和效果
Development and Effects of an Online Pain Self-management Program for Knee Osteoarthritis.
- 新一代二硅酸锂陶瓷的表面、比色和光学性能
Surface, Colorimetric, and Optical Properties of New-Generation Lithium Disilicate Ceramics.
- 临床护士作为数字守护者:揭示人工智能时代数字韧性的关键决定因素
Clinical nurses as digital guardians: unlocking the key determinants of digital resilience in the AI era.
- 远程缺血预处理对急性缺血性卒中患者梗死生长的影响:来自RESIST试验的亚组分析
Remote Ischemic Conditioning on Infarct Growth in Patients With Acute Ischemic Stroke: Subgroup Analysis From the RESIST Trial.
- 培养证实的肺炎克雷伯菌感染的ICU患者死亡率的机器学习辅助预后模型:一项初步的单中心回顾性队列研究
{"_":"Machine learning-assisted prognostic model for mortality in ICU patients with culture-confirmed infection: a preliminary single-center retrospective cohort study.","i":["Klebsiella pneumoniae"]}
- 牙周炎作为骨重塑炎症解耦的模型
Periodontitis as a Model for Inflammatory Uncoupling of Bone Remodeling.
- 甜菜苷通过多途径对多西他赛肾毒性的肾脏保护作用:炎症、内质网应激、细胞凋亡和铁死亡的调控
Multi-Pathway Renoprotection by Betanin Against Docetaxel Nephrotoxicity: Modulation of Inflammation, ER Stress, Apoptosis, and Ferroptosis.
- 唾液催产素研究强烈坚持早期理论,尽管新的框架将神经肽归因于多种作用
Salivary oxytocin research clings strongly to early theories, despite new frameworks attributing versatile roles to the neuropeptide.
- 远程缺血预处理对血管内支架植入患者脑血流调节的疗效:一项随机对照试验
Efficacy of remote ischemic conditioning on cerebral blood flow regulation in patients with endovascular stenting: a randomized controlled trial.
- 正确认识结核病是卡纳塔克邦农村2型糖尿病患者风险感知的决定因素
Correct knowledge of tuberculosis as a determinant of risk perception among patients with type 2 diabetes mellitus in rural Karnataka.
- 用于甲状腺结节筛查的自主机器人超声系统的可行性和初步验证:一项试点前瞻性研究
Feasibility and preliminary validation of an autonomous robotic ultrasound system for thyroid nodule screening: a pilot prospective study.
- 中国眼科患者对中医药的态度、认知和实践:一项横断面研究
Attitude, perception and practice towards traditional Chinese medicine among Chinese ophthalmic patients: A cross-sectional study.
- 选定气道清除技术对机械通气成年ICU患者的生理和临床影响:一项无荟萃分析的系统综述和综合
Physiological and clinical effects of selected airway clearance techniques in mechanically ventilated adult ICU patients: a systematic review and synthesis without meta-analysis.
- Circ-0048766的表征:一种通过miR-329-3p/CXCR4轴促进三阴性乳腺癌症进展并受METTL3调节的致癌环状rna
Characterization of Circ_0048766: an oncogenic circular rna promoting triple-negative breast cancer progression via the miR-329-3p/CXCR4 axis and regulated by METTL3.
- 手术治疗的T1-4N1-2M0非小细胞肺癌的淋巴结亚类化和辅助治疗的预后意义:一项单中心回顾性研究
Prognostic significance of nodal subclassification and adjuvant therapy in surgically treated T1-4N1-2M0 non-small cell lung cancer: a single-center retrospective study.
- 精英运动员和精英残疾人运动员的口腔健康认知:社会心理影响、运动表现
Oral health perceptions among elite athletes and elite para-athletes: psychosocial impacts, sports performance.
- 缺氧缺血性脑病
Hypoxic Ischemic Encephalopathy.
- 他汀类药物依折麦布与高强度他汀类药物在老年患者中的代谢和安全性结果
Metabolic and Safety Outcomes of Statin-Ezetimibe Versus High-Intensity Statin in Older Patients.
- 基于血液的生物标志物预测阿尔茨海默病精神病的差异性纵向下降:来自两个队列的证据
Blood-Based Biomarkers Predict Differential Longitudinal Decline in Alzheimer's Disease Psychosis: Evidence from Two Cohorts.
- 母亲的经历改变了婴儿哭声的全脑表现
Maternal experience alters brain-wide representation of infant cries.
- 智能响应合金支架在时间上调节免疫成骨轴,用于治疗感染性骨缺损
Intelligent responsive alloy scaffold temporally regulates the immune-osteogenic axis for the treatment of infectious bone defects.
- 新冠肺炎大流行对按性别、年龄和心理健康状况分层的身体残疾患者家庭护理使用的影响:使用管理健康数据的队列研究
The Impact of the COVID-19 Pandemic on Homecare Use for Individuals with Physical Disabilities Stratified by Sex, Age, and Mental Health Condition: A Cohort Study Using Administrative Health Data.
- SGLT2抑制剂和慢性肾病:从血流动力学到代谢的肾脏保护机制的叙述性综述
SGLT2 inhibitors and chronic kidney disease: a narrative review of nephroprotective mechanisms from hemodynamics to metabolism.
- 中枢神经系统疾病经鼻给药的全球趋势和发展前沿(2000-2025):文献计量分析和系统综述
Global Trends and Evolving Frontiers in Intranasal Delivery for CNS Diseases (2000-2025): A Bibliometric Analysis and Systematic Review.
- 干扰素-α作为干燥综合征的精准医学工具:一项队列和实验医学研究
Interferon-α as a precision medicine tool in Sjögren's disease: a cohort and experimental medicine study.
- L5-S1峡部裂和退行性腰椎滑脱的不同区域骨质量模式:对椎弓根螺钉松动风险的影响
Distinct regional bone quality patterns in L5-S1 isthmic and degenerative spondylolisthesis: implications for pedicle screw loosening risk.
- TROP2靶向揭示了癌症中治疗驱动的细胞状态动力学
TROP2 targeting reveals therapy-driven cell state dynamics in colorectal cancer.
- 1990-2023年按艾滋病毒状况分列的全球、区域和国家结核病和耐多药结核病负担:2023年全球疾病负担研究的系统分析
Global, regional, and national burden of tuberculosis and multidrug-resistant tuberculosis by HIV status, 1990-2023: a systematic analysis for the Global Burden of Disease Study 2023.
- 治疗HER2-阳性转移性乳腺癌症患者的曲妥珠单抗-雷泽替康与焦替尼加卡培他滨(HORIZON-Breast01):一项多中心、开放标签、随机、对照的3期试验的中期分析
Trastuzumab rezetecan versus pyrotinib plus capecitabine for patients with HER2-positive metastatic breast cancer (HORIZON-Breast01): interim analysis of a multicentre, open-label, randomised, controlled, phase 3 trial.
- 肠道共生拟杆菌衍生泛酸缓解代谢综合征
Gut commensal Bacteroides-derived pantothenic acid alleviates metabolic syndrome.
- 年龄对成人原发性肠弥漫性大B细胞淋巴瘤预后的意义:来自SEER数据库的见解
Prognostic significance of age in adult primary intestinal diffuse large B-cell lymphoma: Insights from the SEER database.
- 护理教育数字能力框架的情境化:德尔菲法的发现
Contextualizing the digital competence framework for nursing education: Findings from a Delphi.
- 奥希替尼相关的良性眼部色素沉着:一例病例报告
Osimertinib-Associated Benign Ocular Hyperpigmentation: A Case Report.
- 多发性硬化症的研究进展
Advances in Multiple Sclerosis.
- B7-H4靶向放射治疗可实现实体瘤模型的精确成像和有效治疗
B7-H4-targeted radiotheranostics enable precise imaging and potent therapy across solid tumor models.
- 超越生态失调:微生物代谢产物是慢性鼻窦炎鼻黏膜免疫耐受的关键重塑因素
Beyond dysbiosis: microbial metabolites as key remodelers of nasal mucosal immune tolerance in chronic rhinosinusitis.
- 酒精依赖患者精氨酸加压素和催产素水平及其与病态嫉妒和伴侣暴力的关系:一项病例对照研究
Arginine vasopressin and oxytocin levels in patients with alcohol dependence and their association with morbid jealousy and partner violence: A case-control study.
- 情景记忆和语义记忆对想象力和创造力的贡献
Episodic and semantic memory contributions to imagination and creativity.
- 牙科焦虑患者外周血mRNA和唾液生物标志物的改变:一项横断面研究
Altered peripheral blood mRNA and salivary biomarkers in dental anxiety: a cross-sectional study.
- 从水疱到脑室:水痘感染后儿童A组链球菌脑膜炎——一例病例报告
From vesicles to ventricles: pediatric group a streptococcal meningitis post-varicella infection - a case report.
- 从原料到风味:贵州酸汤的微生物发酵解析
From Raw Materials to Distinct Flavors: Unraveling the Microbial Fermentation of Guizhou Sour Soup.
- 数字健康素养在塑造护士自我效能感和创新工作行为中的作用:一项横断面研究
The role of digital health literacy in shaping nurses' self-efficacy and innovative work behavior: A cross-sectional study.
- 拐杖辅助行走对早期和中期骨坏死患者疼痛、步态和髋关节功能的影响:一项随机试验
Effects of crutch-assisted walking on pain, gait, and hip function in early and middle-stage osteonecrosis: a randomized trial.
- 土茯苓中草药对。以及菲库斯·希塔·瓦尔。通过脂联素受体介导的AMPK信号通路调节线粒体功能来改善运动表现
{"_":"The herbal pair of Roxb. and Vahl. improves exercise performance by regulating mitochondrial function via the adiponection receptors-mediated AMPK signaling pathway.","i":["Smilax glabra","Ficus hirta"]}
- 老年人脑源性神经营养因子、肌少症和数字步态特征:对脑肌轴的见解
Brain-Derived Neurotrophic Factor, Sarcopenia and Digital Gait Characteristics in Older Adults: Insights Into the Brain-Muscle Axis.
- 护理专业学生人工智能采用中的准备焦虑悖论:多维回归分析
The readiness-anxiety paradox in artificial intelligence adoption among nursing students: a multidimensional regression analysis.
- 适应性免疫在神经退行性疾病发病机制中的作用
Adaptive immunity in the pathogenesis of neurodegeneration.
- GLP-1受体激动剂靶向AMPKα1-HIF1α-PFKFB3代谢脆弱性并增强肝细胞癌对仑伐替尼的应答
GLP-1 receptor agonist targets an AMPKα1-HIF1α-PFKFB3 metabolic vulnerability and enhances Lenvatinib response in hepatocellular carcinoma.
- 综合单细胞和孟德尔随机化分析确定,衰老诱导的脑内皮SPARCL1缺乏是血管性痴呆的关键驱动因素
Integrated single-cell and Mendelian randomization analyses identify aging-induced brain endothelial SPARCL1 deficiency as a key driver of vascular dementia.
- 用鼻内催产素促进边缘型人格障碍患者的自我同情冥想:一项试点研究
Promoting self-compassion meditation with intranasal oxytocin in borderline personality disorder: a pilot study.
- 生物学衰老与膳食氧化平衡评分对美国老年人心脏代谢多重疾病的联合关联
The joint association of biological aging and dietary oxidative balance score with cardiometabolic multimorbidity among U.S. older adults.
- 维生素C、ACSL4和铁老化:灵长类动物研究的机制见解和转化视角
Vitamin C, ACSL4, and Ferro-Aging: Mechanistic Insights and Translational Perspectives from Primate Studies.
- 对齐空间视角的神经机制
The neural mechanisms of aligning spatial perspectives.
- 通过铁稳态和β-catenin/GPX4轴的双重破坏,将硝唑胺重新用作癌症三阴性乳腺癌的新型脱铁诱导剂
Repurposing nitazoxanide as a novel ferroptosis inducer for triple-negative breast cancer via dual disruption of iron homeostasis and the β-catenin/GPX4 axis.
- 远端双蒂"超交叉腿"皮瓣:复杂下肢缺损的挽救性选择
Distal bipedicled "supra cross leg" flap: a salvage option for complex lower limb defects.
- Esketamine用于全身麻醉中的负面情绪和认知功能:系统综述和荟萃分析
Esketamine for negative emotions and cognitive function in general anesthesia: a systematic review and meta-analysis.
- 通过超高效液相色谱-高分辨质谱(UPLC-HRMS)对Staurogyne stenophylla进行化学分析,并对其抗炎潜力进行计算机研究
{"_":"Chemical profiling of via UPLC-HRMS and investigation into its anti-inflammatory potential.","i":["Staurogyne stenophylla","in silico"]}
- 溶酶体阳离子通道TRPML1调节少突胶质细胞骨架
The lysosomal cation channel TRPML1 regulates the oligodendrocyte cytoskeleton.
- 无声协同:同时存在的β-内酰胺酶机制是否会削弱抗菌效果?
Silent Synergy: Is the Presence of Concurrent β-Lactamase Mechanisms Undermining Antimicrobial Effectiveness?
- 自体血补片胸膜固定术成功应用于肺结核继发气胸
Successful use of autologous blood patch pleurodesis in pneumothorax secondary to pulmonary tuberculosis.
- 百里酚靶向PHKA2通过FOXA1/KLF4介导的巨噬细胞极化减轻败血症诱导的心肌细胞焦亡
Targeting PHKA2 by Thymol alleviates sepsis induced cardiomyocyte pyroptosis via FOXA1/KLF4-mediated macrophage polarization.
- Bufalin通过靶向SEC13介导的破骨细胞生成抑制乳腺癌症骨转移
Bufalin suppresses breast cancer bone metastasis through targeting SEC13-mediated osteoclastogenesis.
- 济川汤治疗慢传输型便秘的疗效:注重肠道菌群调节
Therapeutic efficacy of Jichuan decoction in slow-transit constipation: focus on gut microbiota modulation.
- 手术延迟对老年股骨粗隆间骨折患者的临床影响:来自国家住院样本数据库的分析
Clinical effects of surgical delay in older patients with intertrochanteric fractures: analysis from the National Inpatient Sample Database.
- 养血安泰汤通过多靶点调节增殖蜕膜间质细胞的分化来治疗URSA
Yang-Xue-An-Tai Decoction Treats URSA by regulating the differentiation of proliferating decidual stromal cells through multiple targets.
- 苯磺酸瑞马唑仑用于认知障碍患者牙科操作静脉镇静的有效性:一项前瞻性单臂观察性研究
Efficacy of Remimazolam besylate for intravenous sedation in dental procedures for patients with cognitive disabilities: a prospective single-arm observational study.
- 血浆动脉粥样硬化指数和虚弱指数与中老年人关节炎的相关性:一项队列研究
Association of the combined atherosclerosis index of plasma and frailty index with arthritis in middle-aged and older adults: a cohort study.
- 在阿尔茨海默病模型中,早期皮质纹状体过度活跃伴随纹状体胆碱能功能障碍,损害认知灵活性
Early-Stage Corticostriatal Hyperactivity Impairs Cognitive Flexibility Alongside Striatal Cholinergic Dysfunction in an Alzheimer's Disease Model.
- 全身性贫血和糖尿病黄斑水肿的风险以及抗VEGF注射
Systemic Anemia and the Risk of Diabetic Macular Edema and Anti-VEGF Injections.
- 乳酰化驱动的小胶质细胞GCH1-BH4轴抑制神经炎症,是跑步机跑步对小鼠CSDS诱导的抑郁样行为的预防作用的基础
Lactylation-driven microglial GCH1-BH4 axis suppresses neuroinflammation and underlies the preventive effects of treadmill running against CSDS-induced depression-like behaviors in mice.
- 老年胫骨平台骨折:并发症和治疗策略的多中心分析
Geriatric tibial plateau fractures: A multicenter analysis of complications and treatment strategies.
- 新型经导管边缘到边缘修复系统治疗高危原发性二尖瓣反流:2年关键试验结果
Novel Transcatheter Edge-to-Edge Repair System for High-Risk Primary Mitral Regurgitation: 2-Year Pivotal Trial Outcomes.
- 运动中的等待:一种普遍心理体验的运动学视角
Waiting in sport: a kinesiological perspective on a universal psychological experience.
- 中老年关节炎患者C-反应蛋白甘油三酯葡萄糖指数与心血管疾病发病率的相关性:一项基于医院横断面复制的全国性前瞻性队列研究
Association between the C-reactive protein-triglyceride-glucose index and incident cardiovascular disease in middle-aged and older adults with arthritis: a nationwide prospective cohort study with hospital-based cross-sectional replication.
- 社会剥夺和鼻内催产素给药对草原田鼠脑内催产素受体密度的交互影响
Interactive impacts of social deprivation and intranasal oxytocin administration on oxytocin receptor density in prairie vole brains.
- 3'非翻译区的核苷酸变异有助于提高重新出现的乙型脑炎病毒基因型V的毒力和复制效率
Nucleotide variations in 3' untranslated region contribute to the enhanced virulence and replication efficiency of reemerging Japanese encephalitis virus genotype V.
- β-内酰胺类抗生素开发中的共价抑制剂
Covalent Inhibitors in Antimicrobial Drug Development-Beyond β-Lactams.
- 催产素对禁食大鼠空肠移行肌电复合物活性的抑制作用:催产素和GLP-1受体的作用
Inhibitory Effects of Oxytocin on Jejunal Migrating Myoelectric Complex Activity in Fasted Rats: Role of Oxytocin and GLP-1 Receptors.
- 单细胞图谱揭示了一种新的CAF亚群,该亚群将基质异质性与乳腺癌症亚型的免疫抑制联系起来
Single-cell profiling reveals a novel CAF subpopulation linking stromal heterogeneity to immune suppression in breast cancer subtypes.
- 针对高危铜绿假单胞菌分离株的双β-内酰胺治疗:一项将群体基因组学与定量系统药理学建模和模拟相结合的动态体外感染模型研究
Dual β-lactam therapy against high-risk Pseudomonas aeruginosa isolates: a dynamic in-vitro infection model study integrating population genomics with quantitative systems pharmacology modelling and simulations.
- 慢性应激释放肿瘤内吞噬纤维母细胞-B细胞回路,促进肿瘤生长
Chronic stress unleashes an intratumor phage-fibroblast-B cell circuit to promote tumor growth.
- 电压门控离子通道的昼夜失调协调了跨器官电生理重塑和治疗时机
Circadian dysregulation of voltage-gated ion channels orchestrates cross-organ electrophysiological remodeling and therapeutic timing.
- 可逆性先天性性腺功能减退症:临床治疗的关键
Reversible congenital hypogonadotropic hypogonadism: keys for clinical management.
- 类泛素蛋白NEDD8和SUMO2调控上皮稳态、再生和炎症
Ubiquitin-like proteins NEDD8 and SUMO2 control epithelial homeostasis, regeneration, and inflammation.
- 根据早期体重反应的Tirzepatide疗效和耐受性:SURMOUNT-1和SURMOUNT-2试验的事后分析
Tirzepatide Efficacy and Tolerability According to Early Weight Response: A Post Hoc Analysis of the SURMOUNT-1 and SURMOUNT-2 Trials.
- 护士在支持2型糖尿病成人数字化参与和自我管理中的作用:范围界定综述
Nurses' Roles in Supporting Digital Engagement and Self-Management in Adults with Type 2 Diabetes: A Scoping Review.
- 降钙素基因相关肽靶向治疗前庭偏头痛:观察证据与疗效方向分析的综合
CGRP-Targeting Therapies in Vestibular Migraine: A Synthesis of Observational Evidence with Direction-of-Effect Analysis.
- {"_":"[延龄草皂苷通过促进内质网自噬保护卒中后认知障碍大鼠的神经功能]。","i":["延龄草"]}
{"_":"[ Maxim saponin protects neurological function in rats with post-stroke cognitive impairment by promoting ER-phagy].","i":["Trillium tschonoskii"]}
- 手术室舒适护理对伴有睡眠障碍的甲状腺切除术患者焦虑抑郁和术后康复的影响
The Effect of Comfort Nursing in Operating Room on Anxiety Depression and Postoperative Recovery in Thyroidectomy Patients With Coexisting Sleep Disorders.
- 孤独和紧张在学龄青少年饮酒和网络欺凌受害之间起着中介作用:一项为期两年的纵向研究
Loneliness and nervousness mediate the association between alcohol use and cyberbullying victimization among school-aged adolescents: a two-year longitudinal study.
- 护理人员对儿童干眼症的知识、态度和实践:一项横断面研究
Caregivers' knowledge, attitudes, and practices toward pediatric dry eye disease: a cross-sectional study.
- 肠道微生物群衍生的赖氨酸苯乙酰化会损害线粒体功能,SIRT3可以缓解
Gut microbiota-derived lysine phenylacetylation impairs mitochondrial function and is alleviated by SIRT3.
- CAR T细胞治疗B细胞淋巴瘤后的十年结果
Ten-Year Outcomes after CAR T-Cell Therapy for B-Cell Lymphomas.
- PVN催产素神经元的不同投射调节了对社会威胁的不同防御行为
Distinct projections of PVN oxytocin neurons regulate the divergent defensive behaviors in response to social threat.
- 黄芪粗多糖通过保持血脑屏障的完整性和抑制水母毒液小鼠GSDMD介导的焦亡来改善认知障碍
Crude Astragalus polysaccharides ameliorate cognitive impairment by preserving blood-brain barrier integrity and suppressing GSDMD-mediated pyroptosis in jellyfish-envenomed mice.
- 饮食干预与努力感相互作用,提高耐力表现:简要叙述综述
Dietary interventions interact with the perception of effort and enhance endurance performance: a brief narrative review.
- 缺血性卒中中NMDA受体靶向神经保护:整合时空动力学、亚型选择性和信号通路的3S框架
NMDA Receptor-Targeted Neuroprotection in Ischemic Stroke: The 3S Framework Integrating Spatiotemporal Dynamics, Subtype Selectivity, and Signaling Pathways.
- 胡桃醌通过JNK/P38 MAPK通路诱导骨肉瘤细胞GSDME轴细胞焦亡
Juglone induces GSDME axis pyroptosis in osteosarcoma cells via the JNK/P38 MAPK pathway.
- 儿童高血压与心血管肾代谢疾病的交叉
Intersection of Pediatric Hypertension and Cardiovascular-Kidney-Metabolic Disease.
- 蒲公英类外泌体纳米囊泡通过SLC7A11调节的铁下垂减轻脓毒症诱导的急性肾损伤
Dandelion exosome-like nanovesicles alleviate sepsis-induced acute kidney injury via SLC7A11-regulated ferroptosis.
- 【基于XGBoost SHAP模型的闽三角城市群生态环境质量时空演变及驱动因素分析】
[Analysis of Spatiotemporal Evolution and Driving Factors of Ecological Environment Quality in the Min Delta Urban Agglomeration Based on XGBoost-SHAP Model].
- RBM15通过m6A修饰调节FOXO3稳定性,促进高血糖诱导的视网膜内皮细胞损伤
RBM15 promotes hyperglycemia-induced retinal endothelial cell injury by regulating FOXO3 stability via m6A modification.
- 睑板腺功能障碍的年龄谱:横断面研究
Age Spectrum of Meibomian Gland Dysfunction: A Cross-Sectional Study.
- 中国解除COVID-19封锁前后胎儿镜像右位心的比较分析
A comparative analysis of fetal mirror-image dextrocardia in China pre- and post-COVID-19 lockdown lifting.
- 中性粒细胞、成纤维细胞和破骨细胞在牙周炎中的作用:转录组学和单细胞分析
The role of neutrophils, fibroblasts, and osteoclasts in periodontitis: A transcriptomic and single-cell analysis.
- 白癜风的神经心理因素:机制和临床应用
Neuropsychological Factors in Vitiligo: Mechanisms and Clinical Application.
- 杯状物免疫串扰为克服免疫疗法耐药性提供了策略
Cuproptosis-immunity crosstalk informs strategy to overcome immunotherapy resistance.
- 临床护士数字领导力量表:一种工具的开发和验证
Digital Leadership Scale for Clinical Nurses: Development and Validation of an Instrument.
- 长期阻力训练与2型糖尿病风险
Long-Term Resistance Training and Risk of Type 2 Diabetes.
- 脑肿瘤手术患者使用和不使用低血压预测指数工具的术中低血压结果比较:一项随机对照试验
Comparison of Intraoperative Hypotension Outcomes With and Without Hypotension Prediction Index Tool in Patients Undergoing Brain Tumor Surgery: A Randomized Controlled Trial.
- 运动衍生的外泌体miR-151-3p:一种治疗脊髓损伤的创新抗炎和抗氧化疗法
Exercise-derived exosomal miR-151-3p: An innovative anti-inflammatory and antioxidant therapeutic for spinal cord injury.
- TEAS联合五音音乐疗法对阈下抑郁大学生主客观指标的调节作用
Modulation of subjective and objective indicators in college students with subthreshold depression by TEAS combined with five-tone music therapy.
- 代谢功能障碍相关脂肪变性肝病中的胰岛素样生长因子结合蛋白
Insulin-like growth factor binding proteins in metabolic dysfunction-associated steatotic liver disease.
- 通过电刺激促进人类神经肌肉类器官的成熟
Enhancing Maturation of Human Neuromuscular Organoids via Electrical Stimulation.
- 中风幸存者日常生活功能障碍活动预测模型的开发和验证:CHARLS队列的见解
Development and validation of a prediction model for activities of daily living dysfunction among stroke survivors: insights from the CHARLS cohort.
- 归因于脂葡萄糖功能障碍的卒中负担轨迹和生物标志物验证:来自2023年全球疾病负担(GBD)和中国健康与退休纵向研究(CHARLS)的证据
Burden trajectories of stroke attributable to lipid-glucose dysfunction and biomarker validation: evidence from the global burden of disease (GBD) 2023 and the China health and retirement longitudinal study (CHARLS).
- 退行性腰椎疾病中的步态分析:临床应用、生物标志物和新兴技术——一项系统综述
Gait analysis in degenerative lumbar spine diseases: clinical applications, biomarkers, and emerging technologies - a systematic review.
- 在暴饮暴食动物模型中,外周催产素给药可减少雄性大鼠的食物摄入量和强迫性行为
Peripheral oxytocin administration decreases the food intake and compulsive-like behavior in male rats in an animal model of binge-type eating.
- 婴儿、儿童和青少年缺铁和缺铁性贫血的预防、筛查、诊断和治疗:临床报告
Prevention, Screening, Diagnosis, and Treatment of Iron Deficiency and Iron Deficiency Anemia in Infants, Children, and Adolescents: Clinical Report.
- 替代蛋白质的进展和挑战:从生物技术到可持续粮食生产
Advances and challenges in alternative proteins: From biotechnology to sustainable food production.
- 基于中国健康与养老追踪调查(CHARLS)的前瞻性队列研究:C反应蛋白甘油三酯葡萄糖指数与中国内脏脂肪指数(CTI-CVAI)的累积暴露和纵向暴露模式与中国中老年人新发心血管疾病的风险
Cumulative exposure and longitudinal exposure pattern of C-reactive protein-triglyceride-glucose index combined with Chinese visceral adiposity index (CTI-CVAI) and the risk of new-onset cardiovascular disease in middle-aged and older Chinese adults: a prospective cohort study based on the China Health and Retirement Longitudinal Survey (CHARLS).
- 血浆p-Tau217和Aβ42/Aβ40介导轻度抑郁症状与认知障碍之间的关联
Plasma p-Tau217 and Aβ42/Aβ40 mediate the association between minimal depressive symptoms and cognitive impairment.
- 极性蛋白MALS3通过促进TAZ失活和泛素依赖性降解来抑制乳腺癌症干细胞样特性
Polarity protein MALS3 suppresses breast cancer stem cell-like properties by promoting TAZ inactivation and ubiquitination-dependent degradation.
- 运动作为2型糖尿病的靶向治疗:一种基于表型的适应性体力活动临床优先级框架
Exercise as targeted therapy in type 2 diabetes: a phenotype-informed clinical prioritisation framework for adapted physical activity.
- 阴道自体组织修复对不同脆弱程度盆腔器官脱垂的疗效和安全性
Efficacy and safety of vaginal native tissue repair for pelvic organ prolapse across frailty levels.
- 基于蛋白质组学的芹菜素介导的TNF-α刺激的ARPE-19细胞抗炎作用的表征
Proteomics-based characterization of apigenin-mediated anti-inflammatory effects in TNF-α-stimulated ARPE-19 cells.
- 骨质疏松症中的炎性细胞死亡网络:焦亡、铁下垂的机制,以及它们与骨免疫重塑中的凋亡、自噬和PANoptosis的相互作用
Inflammatory cell death networks in osteoporosis: Mechanisms of pyroptosis, ferroptosis, and their crosstalk with apoptosis, autophagy, and PANoptosis in bone immune remodeling.
- 2型糖尿病成人患者转氨酶及长期血糖控制的个体内季节性变异(JDDM 85)
Within-Person Seasonal Variability of Aminotransferases and Long-Term Glycemic Control in Adults With Type 2 Diabetes (JDDM 85).
- 预防盆底疾病:公共卫生项目范围综述
Preventing Pelvic Floor Disorders: A Scoping Review of Public Health Programs.
- 腹部按摩预防骨科术后便秘的效果:一项系统评价
The Effect of Abdominal Massage in Preventing Constipation After Orthopedic Surgery: A Systematic Review.
- 轻度创伤性脑损伤后6个月预后模型的外部验证
External Validation of a Prognostic Model for Outcome After Mild Traumatic Brain Injury at 6 Months Post Injury.
- SIRT1-p53轴驱动铁老化样程序,加重子痫前期滋养细胞功能障碍
The SIRT1-p53 axis drives a ferro-aging-like program and aggravates trophoblast dysfunction in preeclampsia.
- 选择性激光小梁成形术减轻地塞米松诱导的人小梁网细胞肌成纤维细胞样转化和功能障碍
Selective Laser Trabeculoplasty Mitigates Dexamethasone-Induced Myofibroblast-Like Transformation and Dysfunction in Human Trabecular Meshwork Cells.
- 芸薹属蔬菜的硫代葡萄糖苷衍生风味化学:形成、转化、稳定性和感官意义
Glucosinolate-Derived Flavor Chemistry of Brassica Vegetables: Formation, Transformation, Stability, and Sensory Implications.
- LINC00222通过调控FOXO3干扰β-catenin信号通路并抑制前列腺癌进展
LINC00222 regulates FOXO3 to interfere with β-catenin signaling pathway and suppresses prostate cancer progression.
- 评估代谢产物生物标志物候选物在检测肝硬化患者HCC中的作用
Evaluation of metabolite biomarker candidates in detecting HCC in patients with liver cirrhosis.
- 具有多酶样活性和谷胱甘肽耗竭能力的富G ssDNA模板Cu纳米簇的体外细胞毒性增强
Enhanced in vitro cytotoxicity of G-rich ssDNA-templated Cu nanoclusters with multienzyme-like activity and glutathione depletion capacity.
- 中枢杏仁核蓝斑通路介导慢性压力下的疼痛
A central amygdala-locus coeruleus pathway mediating pain under chronic stress.
- 来曲唑与生精失败男性不育:一项随机临床试验
Letrozole and Infertility Among Males With Spermatogenic Failure: A Randomized Clinical Trial.
- 抗生素效力和耐药性:分析和微生物学方法的批判性综述
Antibiotic Potency and Resistance: A Critical Review of Analytical and Microbiological Methodologies.
- 妇幼保健护士的人工智能素养和态度:中国新手和专家的多中心心理网络分析
AI literacy and attitudes among maternal and child health nurses: a multicenter psychological network analysis of novices and experts in China.
- DNAJB9阳性原纤维性肾小球肾炎患者的临床病理特征和预后
Clinicopathologic features and outcomes of patients with DNAJB9-positive fibrillary glomerulonephritis.
- DDX21通过刺激缺氧时RNAPII延伸促进癌症生长和转移
DDX21 Promotes Breast Cancer Growth and Metastasis via Stimulating RNAPII Elongation During Hypoxia.
- cGAS-STING通路在癌症免疫治疗中的预后价值和治疗潜力
The cGAS-STING pathway in cancer immunotherapy: prognostic value and therapeutic potential.
- 用于结直肠手术后吻合口漏早期预测的多模式生物标志物面板:从炎症到缺血
Multimodal biomarker panel for early prediction of anastomotic leak after colorectal surgery: from inflammation to ischemia.
- 微创单一体位左侧胸入路与食管裂孔入路对比腹腔镜经食管裂孔入路治疗Siewert II型食管胃结合部腺癌的比较研究
Comparison of minimally invasive single-position left transthoracic and esophageal hiatal approach versus laparoscopic transesophageal hiatus approach for Siewert type II adenocarcinoma of the esophagogastric junction.