妊娠中期血清PlGF水平与多普勒超声异常的一致性
Agreement between Mid-pregnancy Serum Placental Growth Factor Levels and Abnormalities in Uterine Doppler Ultrasound Findings.
Agreement between Mid-pregnancy Serum Placental Growth Factor Levels and Abnormalities in Uterine Doppler Ultrasound Findings.
这项前瞻性观察性研究评估了妊娠中期血清胎盘生长因子(PlGF)水平与胎盘功能不全风险孕妇子宫动脉多普勒异常结果之间的一致性。在127名患者中,17%的患者PlGF检测与子宫动脉多普勒结果不一致,且一致性极低(κ=0.07,95%CI,-0.13,0.28),10名子宫动脉多普勒异常患者中只有2名PlGF低。这些发现表明,PlGF和子宫动脉多普勒可识别不同的高危人群,在胎盘风险分层中不应互换使用。
This prospective observational study evaluated the concordance between mid-pregnancy serum placental growth factor (PlGF) levels and abnormal uterine artery Doppler findings in pregnancies at risk of placental insufficiency. Among 127 patients, PlGF testing was discordant with uterine artery Doppler findings in 17% of cases with minimal agreement (κ 0.07; 95% CI -0.13 to 0.28), and only 2 of 10 patients with abnormal uterine artery Doppler had low PlGF. These findings suggest that PlGF and uterine artery Doppler identify different at-risk populations and should not be used interchangeably in placental risk stratification.
Adelaide Burrows, Jennifer A Hutcheon, Eda Karacabeyli, James Andrews, Chantal Mayer, Jessica Liauw. Agreement between Mid-pregnancy Serum Placental Growth Factor Levels and Abnormalities in Uterine Doppler Ultrasound Findings.. Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC. 2026; doi:10.1016/j.jogc.2026.103455.
Adelaide Burrows, Jennifer A Hutcheon, Eda Karacabeyli, James Andrews, Chantal Mayer, Jessica Liauw (2026). Agreement between Mid-pregnancy Serum Placental Growth Factor Levels and Abnormalities in Uterine Doppler Ultrasound Findings.. Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC. https://doi.org/10.1016/j.jogc.2026.103455
Adelaide Burrows, Jennifer A Hutcheon, Eda Karacabeyli, James Andrews, Chantal Mayer, Jessica Liauw. Agreement between Mid-pregnancy Serum Placental Growth Factor Levels and Abnormalities in Uterine Doppler Ultrasound Findings.[J]. Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC, 2026 doi:10.1016/j.jogc.2026.103455.
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