文献详情页索引 · 第 2 页

第 501–1,000 个,共 8,991 个页面。

  1. 基于FTIR光谱利用临床正常指甲鉴别脂溢性皮炎与头皮银屑病

    FTIR spectroscopy-based differentiation of seborrheic dermatitis and scalp psoriasis using clinically normal fingernails.

  2. 植物性别对雌雄异株物种内生微生物多样性及群落构建的影响

    Impact of plant sex on endophytic microbial diversity and community assembly in dioecious species.

  3. 内镜下胃底静脉曲张组织胶注射后脾梗死:倾向性评分匹配分析中的发生率、探索性相关因素及临床结局

    Splenic infarction after endoscopic glue injection for gastric varices: proportion, exploratory correlates, and clinical outcomes from a propensity score-matched analysis.

  4. 深度学习驱动的单细胞脂质组学用于胃癌腹膜转移的早期诊断和分子分型

    Early diagnosis and molecular classification of gastric cancer peritoneal metastasis by deep learning-driven single-cell lipidomics.

  5. 一种用于紧急止血的光固化及多西环素稳定的丝素蛋白/单宁酸组织粘合剂

    A light-cured and doxycycline stabilized silk fibroin/tannin acid tissue adhesive for emergency hemorrhage.

  6. 在英国9,429名成年人中,EB病毒血清状态与感染相关死亡率之间无关联:一项英国生物银行研究

    No association between Epstein-Barr Virus serostatus and infection-related mortality in 9,429 British adults: a UK Biobank study.

  7. 使用低增益放大管理功能性听力困难:听觉加工评估病例报告

    Management of Functional Hearing Difficulties Using Low-Gain Amplification: Case Reports on Auditory Processing Evaluations.

  8. [肺复张手法联合个体化呼气末正压对高血压患者肺切除术后肺部并发症及围术期血流动力学的影响]

    [Effects of a lung recruitment maneuver combined with individualized positive end-expiratory pressure on postoperative pulmonary complications and perioperative hemodynamics in hypertensive patients undergoing pulmonary resection].

  9. BCR-NF-κB与IL-4Rα-STAT6信号的合成协同构成功能性IgE类别转换重组的主检查点

    Synthetic coincidence of BCR-NF-κB and IL-4Rα-STAT6 signaling constitutes a master checkpoint for functional IgE class switch recombination.

  10. [原发性醛固酮增多症患者发生心血管-肾脏-代谢综合征4期的相关因素分析]

    [Analysis of related factors for the occurrence of cardiovascular-renal-metabolic syndrome stage 4 in patients with primary aldosteronism].

  11. 转录后调控维持人神经祖细胞的神经发生潜能

    Post-transcriptional regulation maintains neurogenic potential of human neural progenitor cells.

  12. 用于分析与严重先天性中性粒细胞减少症相关的SRP54突变功能的酵母模型

    A yeast model for the functional analysis of SRP54 mutations associated with severe congenital neutropenia.

  13. 在小鼠中使用人源类器官进行发育性异种皮层移植

    Developmental xenocortication using human-derived organoids in mice.

  14. 多酚对粘接强度和牙本质酶解的影响

    Accessing Polyphenols Effect on Bond Strength and Dentin Enzymatic Degradation.

  15. 乳腺癌诊断中的简化MRI方案:叙述性综述

    Abbreviated MRI Protocols in Breast Cancer Diagnosis: A Narrative Review.

  16. 中国久坐职业成人中与零时运动相关的久坐行为减少准备度的心理社会相关因素:横断面研究

    Psychosocial Correlates of Sedentary Behavior Reduction Readiness Relevant to Zero-Time Exercise Among Chinese Adults in Sedentary Occupations: Cross-Sectional Study.

  17. 2026年iCatCare关于猫慢性肾病诊断和管理的共识指南

    2026 iCatCare consensus guidelines on the diagnosis and management of chronic kidney disease in cats.

  18. 克罗恩病中功能网络组织的破坏:与焦虑相关的内感受改变

    Disrupted Functional Network Organization in Crohn's Disease: Interoceptive Alterations Linked to Anxiety.

  19. 肺癌中LINC00511和MDM2/MDM4的影响:对免疫治疗策略的启示

    {"_":".","b":["The influence of LINC00511 and MDM2/MDM4 in lung carcinoma: Implications for immunological therapeutic strategies"]}

  20. MiPP2C44促进拟南芥早花并增强芒果毛状根的非生物胁迫耐受性

    MiPP2C44 promotes early flowering in Arabidopsis and enhances abiotic stress tolerance in mango hairy roots.

  21. Zinner综合征:一例病例报告

    Zinner Syndrome: A Case Report.

  22. 具有动态共价和超分子交联的聚(衣康酸)水凝胶用于高且可调的机械性能

    Poly(itaconic Acid) Hydrogels with Dynamic Covalent and Supramolecular Cross-Links for High and Tunable Mechanical Properties.

  23. 人类SRP亚基协调蛋白质靶向与mRNA质量控制

    Human SRP Subunits Coordinate Protein Targeting and mRNA Quality Control.

  24. 非老年成人肱骨近端骨折的锁定钢板固定:短期结局分析

    Locked Plate Fixation of Proximal Humerus Fractures in Non-elderly Adults: Analysis of Short-Term Outcomes.

  25. 基于RNA的方法在肥胖诊断和治疗中的应用

    RNA-based approaches in the diagnosis and treatment of obesity.

  26. 瘦型MAFLD的临床和生化表型:横断面研究中基于机器学习的生物标志物识别和统计学关联分析

    Clinical and biochemical phenotypes of Lean MAFLD: machine learning-based biomarker identification and statistical association analysis in a cross-sectional study.

  27. {“_”:“更正:母乳的核心岩藻糖基化-聚糖通过RORγt Treg细胞中的肠道微生物群依赖性调节赋予早期生命免疫耐受。”,“i”:[“N”],“sup”:[”+“]}

    {"_":"Correction: Core fucosylation of maternal milk -glycans imparts early-life immune tolerance through gut microbiota-dependent regulation in RORγt Treg cells.","i":["N"],"sup":["+"]}

  28. 瘦型和非瘦型MASLD中新发慢性肾病的风险及尿酸与HDL比值的预测价值:一项前瞻性队列和多组学研究

    Incident chronic kidney disease risk and the predictive value of the uric acid-to-HDL ratio in lean and non-lean MASLD: a prospective cohort and multi-omics study.

  29. 二甘醇二苯甲酸酯作为一种新兴增塑剂通过靶向MMP3干扰骨形成:来自生物信息学和体外验证的见解

    Diethylene glycol dibenzoate an emerging plasticizer disrupts bone formation via MMP3 targeting: Insights from bioinformatics and in vitro validation.

  30. 超声引导下的肌肉骨骼入路

    Ultrasound-Guided Musculoskeletal Approach.

  31. 实现癌症基本药物依托泊苷和替尼泊苷酵母的可持续供应

    Enabling sustainable supply of the essential cancer medicines etoposide and teniposide in yeast.

  32. 含迷迭香、丁香和百里香精油的静电纺丝醋酸纤维素纤维的制备与性能

    Preparation and Properties of Electrospun Cellulose Acetate Fibers Containing Rosemary, Clove, and Thyme Essential Oils.

  33. 单钢板与双钢板重建治疗肱骨近端骨折:临床结局比较

    Proximal humerus fractures treated with single or dual-plate constructs: a comparison of clinical outcomes.

  34. 双醛菠萝淀粉作为反应性碳水化合物平台用于吡啶基-酰腙交联网络在Au和Pd回收中的应用

    Dialdehyde pineapple starch as a reactive carbohydrate platform for pyridyl-acylhydrazone crosslinked networks in Au and Pd recovery.

  35. 光子治疗仪联合超声清创在老年三四期压力性损伤中的应用

    Application of photon therapy instrument combined with ultrasonic debridement in senile third and fourth stage pressure injuries.

  36. 闭合复位外固定与切开复位锁定钢板内固定对老年桡骨远端骨折患者术后腕关节功能的影响

    Effect of closed reduction with external fixation versus open reduction and locking plate internal fixation on postoperative wrist function in elderly patients with distal radius fractures.

  37. 肝星状细胞中ITGBL1-MYH9相互作用作为机械调节因子控制小鼠肝纤维化

    ITGBL1-MYH9 interaction in hepatic stellate cells acts as a mechanoregulator controlling liver fibrosis in mice.

  38. 孕期砷暴露:对母体和子代心血管健康的影响

    Arsenic Exposure During Pregnancy: Impacts to Maternal and Offspring Cardiovascular Health.

  39. 光学散射衍生的红细胞参数在快速识别和校正血脂干扰方面的临床应用

    Clinical utility of optical scatter-derived red blood cell parameters for the rapid identification and correction of lipemic interference.

  40. 胞质跨膜螺旋通过EMC6驱动的静电相互作用进入内质网膜

    Cytosolic transmembrane helices enter the ER membrane through EMC6-driven electrostatic interactions.

  41. 线粒体STING调控糖尿病心肌病中的糖酵解重编程

    Mitochondrial STING Governs Glycolytic Reprogramming in Diabetic Cardiomyopathy.

  42. 健脾柔肝法辅助乐伐替尼治疗:一项关于维持中晚期肝细胞癌相对剂量强度及减少毒性驱动停药的真实世界研究

    Jianpi Rougan Method in Support of Lenvatinib Therapy: A Real-World Study on Maintaining Relative Dose Intensity and Mitigating Toxicity-Driven Discontinuation in Intermediate-to-Advanced HCC.

  43. 锁骨内固定物取出适应证、时机和影像学检查的实践模式:一项针对德语区肩关节外科医生的调查

    Practice patterns in indications, timing, and imaging for clavicle hardware removal: a survey among German-speaking shoulder surgeons.

  44. 靶向肝星状细胞中的AREL1可减轻MASH相关肝纤维化

    Therapeutic targeting of AREL1 in hepatic stellate cells attenuates MASH-related liver fibrosis.

  45. 心血管-肾脏代谢综合征

    Cardiovascular-kidney-metabolic (CKM) syndrome.

  46. 门静脉多普勒在围手术期和重症监护医学中的应用:生理学、测量方法和临床应用

    Portal vein Doppler in peri-operative and critical care medicine: Physiology, measurement and clinical applications.

  47. 外泌体circ_0005397通过miR-204-5p/STAT6轴诱导M2巨噬细胞极化,促进TNBC进展

    Exosomal circ_0005397 promotes TNBC progression by inducing M2 macrophage polarization via the miR-204-5p/STAT6 axis.

  48. 在脂多糖诱导的子宫内膜炎中,藜提取物通过调节TLR4/SLC7A11信号通路减轻子宫内膜上皮细胞的铁下垂

    Clinopodium chinense extract alleviates ferroptosis of endometrial epithelial cells via regulating TLR4/SLC7A11 signaling pathway in lipopolysaccharide-induced endometritis.

  49. 药物诱导的低温在急性缺血性卒中中的转化潜力

    The translational potential of drug-induced hypothermia in acute ischemic stroke.

  50. 使用虚拟非对比光子计数CT区分机械血栓切除术后出血和造影剂外渗

    Differentiating Hemorrhage and Contrast Extravasation After Mechanical Thrombectomy Using Virtual Non-Contrast Photon-Counting CT.

  51. 解读多囊卵巢综合征:流行病学、分子机制、动物模型和不断扩大的治疗前景的综合综述

    Decoding polycystic ovary syndrome: an integrated review of epidemiology, molecular mechanisms, animal models, and the expanding therapeutic landscape.

  52. 主动脉夹层手术患者全身炎症反应指数与术后临床结果的相关性:荟萃分析的系统综述

    Association of systemic inflammation response index with postoperative clinical outcomes among operated patients with aortic dissection: a systematic review with meta-analysis.

  53. 从衰老到阿尔茨海默病:晚年大脑DNA甲基化变化一致

    From aging to Alzheimer's disease: concordant brain DNA methylation changes in late life.

  54. 用于可穿戴电子设备的低轮廓共形三频纺织天线,使用导电织物和PDMS

    Low-profile conformal triple-band textile antenna using conductive fabric and PDMS for wearable electronics.

  55. 解码精神分裂症的神经发育变化:神经源性改变的全面系统综述

    Decoding neurodevelopmental changes in schizophrenia: a comprehensive systematic review of neurogenic alterations.

  56. 一种新的非正则Src哺乳动物STE20样激酶1(MST1)-Akt/糖原合酶激酶-3β(GSK3β)通路驱动血小板活化和血栓形成

    A novel noncanonical Src-MST1-Akt/GSK3β pathway drives platelet activation and thrombosis.

  57. 巨噬细胞膜仿生脂质体靶向递送及ROS响应性释放celastrol缓解急性肾损伤

    Targeted delivery and ROS-responsive release of celastrol by a macrophage membrane biomimetic liposome alleviates acute kidney injury.

  58. 山楂原花青素提取物通过重塑肠道微生物群驱动的胆汁酸谱和调节FXR通路,减轻小鼠非酒精性脂肪肝

    {"_":"The hawthorn () procyanidin extract attenuates nonalcoholic fatty liver disease in mice remodeling the bile acid profile driven by gut microbiota and regulating the FXR pathway.","i":["Crataegus pinnatifida","via"]}

  59. 放置子宫栓对骨盆解剖的影响:一项使用直立MRI的前瞻性观察研究

    The Effect of Pessary Insertion on Pelvic Anatomy: A Prospective Observational Study Using Upright MRI.

  60. 毒液免疫疗法的衰退:患者特征和临床结果

    Declining venom immunotherapy: patient characteristics and clinical outcomes.

  61. DNMT1介导的中枢杏仁核至蓝斑回路导致小鼠慢性疼痛相关抑郁

    DNMT1-mediated central amygdala to locus coeruleus circuit contributes to chronic pain-related depression in mice.

  62. UFM1受体的系统发现揭示了DNA修复中指导非同源末端连接的调控模块

    Systematic discovery of UFM1 receptors reveals a regulatory module in DNA repair directing non-homologous end-joining.

  63. 新型a类β-内酰胺酶BAS-1的特性研究

    {"_":"Characterization of BAS-1, a novel class A β-lactamase encoded in .","i":["Bacteroides thetaiotaomicron"]}

  64. L5/S1前路腰椎椎间融合术:解剖学和技术考量

    L5/S1 anterior lumbar interbody fusion: anatomical and technical considerations.

  65. 肝硬化患者食管和胃静脉曲张的临床试验评估:一个集中式盲法评估系统

    Assessment of Esophageal and Gastric Varices in Patients With Cirrhosis for Clinical Trials: A Centralized Blinded Evaluation System.

  66. 疼痛沟通和外化的结构化和具体化框架(SAEF)

    A structured and embodied framework (SAEF) for pain communication and externalization.

  67. 病例报告:一名患有SLE和继发性APS的孕妇成功地非手术治疗了巨大的孤立性三尖瓣Libman Sacks心内膜炎

    Case Report: successful non-surgical management of massive isolated tricuspid Libman-Sacks endocarditis in a pregnant patient with SLE and secondary APS.

  68. FABP4在类风湿性关节炎相关性骨质疏松症中的潜在作用:综合生物信息学分析和实验验证

    The potential involvement of FABP4 in rheumatoid arthritis-associated osteoporosis: a comprehensive bioinformatics analysis and experimental validation.

  69. NLR炎症小体通路:代谢性疾病发病机制与治疗的关键靶点

    NLR inflammasome pathways: key targets for pathogenesis and therapy of metabolic diseases.

  70. 机器学习将PPARG确定为与CD14/NF-κB信号传导相关的败血症诊断生物标志物:综合转录组学和实验验证

    Machine learning identifies PPARG as a diagnostic biomarker for sepsis linked to CD14/NF-κB signaling: integrated transcriptomics and experimental validation.

  71. 基于临床数据的围绝经期妇女骨质减少的可解释预测机器学习模型:一项回顾性单中心研究

    An explainable predictive machine learning model of osteopenia for perimenopausal women based on clinical data: a retrospective single-center study.

  72. 用于金属增材制造中实时缺陷预测的数字孪生驱动多尺度建模

    Digital twin-driven multiscale modelling for real-time defect prediction in metal additive manufacturing.

  73. 牙周炎和类风湿性关节炎的机制证据

    Periodontitis and Rheumatoid Arthritis-Mechanistic Evidence.

  74. 整合炎症、胰岛素抵抗和内脏脂肪:在一项全国性前瞻性队列研究中,C-反应蛋白甘油三酯葡萄糖中国内脏脂肪指数(CTI-CVAI)与CKM 0-3期的心血管疾病风险相关

    Integrating inflammation, insulin resistance, and visceral adiposity: the C-reactive protein-triglyceride-glucose-Chinese visceral adiposity (CTI-CVAI) index is associated with cardiovascular disease risk across CKM stages 0-3 in a nationwide prospective cohort.

  75. DREAMSPHEN:一项随机对照研究,比较了基于患者精神病表型分层后精神分裂症谱系障碍患者抗精神病药物剂量减少与维持治疗的差异——个性化医疗方法的研究方案

    DREAMSPHEN: a randomised controlled study comparing dose reduction of antipsychotics vs maintenance treatment in schizophrenia spectrum disorder after stratification based on patients' psychotic phenotype - study protocol of a personalised medicine approach.

  76. 慢性阻塞性肺疾病合并胃肠功能障碍的中医护理干预:文献计量学和知识图谱分析,2015-2025

    Traditional Chinese Medicine Nursing Intervention in Chronic Obstructive Pulmonary Disease With Gastrointestinal Dysfunction: Bibliometric and Knowledge Graph Analysis, 2015-2025.

  77. 释放植物衍生天然产物的力量:对痴呆症相关疾病的认知健康和神经精神症状的治疗益处

    Unlocking the Power of Plant-Derived Natural Products: Therapeutic Benefits for Cognitive Health and Neuropsychiatric Symptoms in Dementia-Related Diseases.

  78. Spinosin对雄性小鼠的催眠作用是由腺苷A2A受体介导的

    {"_":"The Hypnotic Effect of Spinosin Is Mediated by Adenosine A Receptors in Male Mice.","sub":["2A"]}

  79. 重症监护室的败血症心肌病:超声心动图表型、整体纵向应变和右心室评估

    Septic Cardiomyopathy in the ICU: Echocardiographic Phenotypes, Global Longitudinal Strain, and Right Ventricular Assessment.

  80. 瘦腰肌面积与CLTI下肢血管重建术后的住院时间有关

    Lean Psoas Muscle Area Is Associated with Length of Stay After Lower Limb Revascularization for CLTI.

  81. 腹腔镜骶管固定与阴道骶管固定治疗盆腔器官脱垂:手术结果和生活质量的回顾性比较

    Laparoscopic Sacropexy Versus Vaginal Sacrospinous Fixation for Pelvic Organ Prolapse: A Retrospective Comparison of Surgical Outcomes and Quality of Life.

  82. 用于牙周炎治疗的微环境响应材料的最新进展

    Recent Advances in Microenvironment-Responsive Materials for Periodontitis Therapy.

  83. 面部创伤中咬合矫正的修复手术

    Revision Surgery for Occlusal Correction in Facial Trauma.

  84. 前胶原1在内质网中组装成相分离的冷凝物

    Procollagen 1 assembles into phase-separated condensates in the endoplasmic reticulum.

  85. 早期感染性休克中的血管加压素或液体

    Vasopressors or Fluids in Early Septic Shock.

  86. 妊娠14-22周子宫动脉多普勒在预测先兆子痫和宫内生长受限中的作用

    Role of uterine artery doppler at 14-22 weeks of gestation in predicting preeclampsia and intrauterine growth restriction.

  87. 急性有氧运动和任务重复对年轻人和老年人执行功能神经相关性的影响:一项交叉fMRI研究

    Effects of Acute Aerobic Exercise and Task Repetition on the Neural Correlates of Executive Function in Young and Older Adults: A Crossover fMRI Study.

  88. 中国东南部临床护士人工智能素养及其影响因素:潜在特征分析

    Artificial intelligence literacy and influencing factors among clinical nurses in southeastern China: a latent profile analysis.

  89. 护士人工智能素养概况及其与循证实践能力的关联:潜在概况分析

    Profiles of artificial intelligence literacy and associations with evidence-based practice competence among nurses: a latent profile analysis.

  90. 非洲裔加勒比人群糖尿病足溃疡微生物组的系统发育分析

    Phylogenetic Profiling of the Diabetic Foot Ulcer Microbiome of an Afro-Caribbean Population.

  91. 克隆造血中对睡眠和运动的突变依赖性反应

    Mutation-dependent responses to sleep and exercise in clonal haematopoiesis.

  92. Hetairos是一种基于组织学的人工智能模型,用于预测中枢神经系统肿瘤甲基化亚型

    Hetairos is a histology-based artificial intelligence model for predicting central nervous system tumor methylation subtypes.

  93. 组胺化通过机械转导信号轴改变胶原基质力学,减轻心肌梗死后的心脏纤维化

    Histaminylation alters collagen matrix mechanics and attenuates cardiac fibrosis post-myocardial infarction via mechanotransduction signaling axis.

  94. 优化血液取样策略,避免前臂甲状旁腺自体移植和动静脉瘘患者出现假PTH升高

    Optimization of blood sampling strategy to avoid spurious PTH elevation in patients with forearm parathyroid autotransplantation and arteriovenous fistula.

  95. 劳累性中暑相关急性肾损伤:新的动物和细胞模型

    Exertional heat stroke-related acute kidney injury: novel animal and cellular models.

  96. 基于aza香豆素的针对不同细胞器的极性探针,用于监测铁下垂和细胞衰老

    Polarity probes targeting different organelles based on aza-coumarin for monitoring ferroptosis and cellular senescence.

  97. 适应性Spo11 RNA编辑门控优化减数分裂I节奏和有丝分裂增殖,同时保持子囊孢子形成

    Adaptive Spo11 RNA editing gate optimizes meiosis I pace and mitotic proliferation while preserving ascospore formation.

  98. 芹菜素微球的制备及其对牙龈卟啉单胞菌的影响

    Preparation of apigenin-loaded microspheres and their effects against Porphyromonas gingivalis.

  99. RS2Z36的剪接调控控制着番茄的卵巢模式和果实生长

    Splicing regulation by RS2Z36 controls ovary patterning and fruit growth in tomato.

  100. 积极心理干预对自杀相关结果的影响:系统综述和荟萃分析

    Effects of positive psychological interventions on suicide-related outcomes: A systematic review and meta-analysis.

  101. 氟西汀相关不良事件信号,重点是癫痫发作:一项基于FAERS数据库、网络药理学和分子对接的研究

    Fluoxetine-associated adverse event signals with a focus on seizure: A study based on the FAERS database, network pharmacology, and molecular docking.

  102. 晨间蓝光疗法对成人原发性和合并失眠患者睡眠和日间症状的有效性:随机对照试验的系统评价和荟萃分析

    Effectiveness of morning blue light therapy on sleep and daytime symptoms in adults with primary and comorbid insomnia: A systematic review and meta-analysis of randomized control trials.

  103. 胰腺癌患者术前化疗后行肠系膜上动脉剥离或切除术后的神经源性腹泻:国际多中心回顾性研究

    Neurogenic diarrhoea after superior mesenteric artery divestment or resection for pancreatic adenocarcinoma following preoperative chemotherapy: international multicentre retrospective study.

  104. 2026年AHA/ACC/ADA/ASN心血管-肾脏代谢综合征预防、检测、评估和管理指南:美国心脏病学会/美国心脏协会临床实践指南联合委员会的报告

    2026 AHA/ACC/ADA/ASN Guideline for the Prevention, Detection, Evaluation, and Management of Cardiovascular-Kidney-Metabolic Syndrome: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.

  105. 远程缺血后处理可减轻神经炎症,并通过IL-9/JAK2-STAT5信号通路为蛛网膜下腔出血后的早期神经恢复提供潜在益处

    Remote Ischemic Postconditioning Attenuates Neuroinflammation and Suggests a Potential Benefit for Early Neurological Recovery after Subarachnoid Hemorrhage via the IL-9/JAK2-STAT5 Signaling Pathway.

  106. 2005年至2024年精益代谢功能障碍相关脂肪变性肝病(精益MASLD)的全球研究趋势:文献计量和可视化分析

    Global research trends of lean metabolic dysfunction-associated steatotic liver disease (lean MASLD) from 2005 to 2024: Bibliometric and visualization analysis.

  107. 四逆汤通过抑制HIF-1α依赖性外泌体整联蛋白信号传导抑制癌症肝转移

    Sini decoction inhibits colorectal cancer liver metastasis by suppressing HIF-1α-dependent exosomal integrin signaling.

  108. 严重发热伴血小板减少综合征流行病学动态的生态特征

    Ecological signature on the epidemiological dynamics of severe fever with thrombocytopenia syndrome.

  109. 结构化远程医疗社区卫生工作者临床医生反馈和糖尿病结果:一项随机临床试验

    Structured Telehealth Community Health Worker-Clinician Feedback and Diabetes Outcomes: A Randomized Clinical Trial.

  110. 间歇性PEG-IFN治疗可以增强HBsAg下降平台期慢性乙型肝炎患者的HBsAg丢失

    HBsAg loss in chronic hepatitis B patients with an HBsAg decline plateau can be enhanced by intermittent PEG-IFN treatment.

  111. 与针灸治疗慢性疼痛相关的脑功能改变:fMRI研究的范围综述

    Functional brain alterations associated with acupuncture for chronic pain: a scoping review of fMRI studies.

  112. 冠状动脉CT血管造影后严重碘造影剂外渗:病例报告

    Severe iodinated contrast extravasation following coronary CT angiography: A case report.

  113. 心脏血管中HIF2的激活会导致动脉重塑、扩张、血栓形成和炎症,从而重新引发川崎病的心脏受累

    Activation of HIF2 in Cardiac Vasculature Leads to Arterial Remodeling, Dilation, Thrombosis, and Inflammation, Recapitulating Cardiac Involvement in Kawasaki Disease.

  114. 循环4β-羟基胆固醇作为CYP3A4活性生物标志物:超越药物研发

    Circulating 4β-hydroxycholesterol as a biomarker of CYP3A4 activity: beyond drug development.

  115. Rehmaninoside D通过与c-Jun相互作用来破坏AP-1复合物并抑制MAPK/NF-κB信号传导,从而预防雌激素缺乏诱导的骨质疏松症

    Rehmannioside D prevents estrogen-deficiency induced osteoporosis by interacting with c-Jun to dismantle the AP-1 complex and suppress MAPK/NF-κB signaling.

  116. 低KIF4A表达与癌症进展和侵袭性表型相关

    Low KIF4A expression is associated with gastric cancer progression and aggressive phenotypes.

  117. 心理应激通过P物质蛋白水解失调和MRGPRX2依赖性肥大细胞活化加剧白癜风

    Psychological stress exacerbates vitiligo via dysregulated proteolysis of substance P and MRGPRX2-dependent mast cell activation.

  118. 铁老化:一种将铁超载、脂质过氧化和细胞衰老联系起来的新范式

    Ferro-aging: A novel paradigm linking iron overload, lipid peroxidation and cellular senescence.

  119. 高血清尿酸与糖尿病肾病进展有关:来自孟德尔随机化分析和动物研究的证据

    High serum uric acid is linked with diabetic kidney disease progression: Evidence from Mendelian randomization analysis and animal study.

  120. 小胶质细胞PICALM:血管性痴呆的新遗传驱动因素和治疗靶点

    Microglial PICALM: A novel genetic driver and therapeutic target in vascular dementia.

  121. 以湿愈合理论为指导,对透明质酸聚硅氧烷凝胶促进伤口修复的机理进行研究

    Mechanistic study on hyaluronic acid polysiloxane gel promoting wound repair guided by wet healing theory.

  122. 鉴定细胞外囊泡microRNAs作为Marek病病毒感染中干扰素α逃逸的潜在促进因素

    Identification of extracellular vesicle microRNAs as potential facilitators of interferon-alpha escape in Marek's disease virus infection.

  123. 通过临床批准的LNPs强制表达BATF可增强过继性T细胞疗法

    Enforced BATF expression via clinically approved LNPs enhances adoptive T-cell therapies.

  124. 运动诱导的超重和肥胖人群全身炎症生物标志物的变化:文献计量分析和荟萃分析综述

    Exercise-induced changes in systemic inflammatory biomarkers in overweight and obese populations: a bibliometric analysis and umbrella review of meta-analyses.

  125. 一种用于糖尿病创面治疗中免疫调节和实时监测的双功能诊疗微针贴片

    A dual functional theranostic microneedle patch for immunomodulation and real time monitoring in diabetic wound therapy.

  126. 重症监护败血症患者室上性心律失常的治疗

    Treatment of supraventricular arrhythmias in critical care patients with sepsis.

  127. 体外重组果蝇Arc衣壳将基因编辑器传递到营养不良的肌肉

    In vitro-reconstituted Drosophila Arc capsids deliver gene editors to dystrophic muscle.

  128. 14个甘油三酯葡萄糖(TyG)相关指标与中老年人新发心血管疾病的相关性:来自CHARLS和ELSA衰老队列的证据

    Association of 14 triglyceride-glucose (TyG)-related indices with new-onset cardiovascular disease in middle-aged and older adults: evidence from the CHARLS and ELSA aging cohorts.

  129. 用于下一代治疗的未开发微生物工厂:药用植物的内生真菌

    Untapped microbial factories for next-generation therapeutics: Endophytic fungi of medicinal plants.

  130. LCAT作为分子开关,在体外调节公鸡精子运动

    LCAT acts as a molecular switch and regulates rooster sperm motility in vitro.

  131. 教育方案和物理治疗管理对改善膝骨性关节炎患者疼痛、症状、日常生活活动和生活质量的影响:系统综述和荟萃分析

    Impact of education protocols and physiotherapeutic management in improving pain, symptoms, activities of daily living, and quality of life in patients with knee osteoarthritis: A systematic review and meta-analysis.

  132. 天然产物网织碱衍生的新型类似物的设计、合成和抗炎评价

    Design, synthesis, and anti-inflammatory evaluation of novel analogues derived from the natural product reticuline.

  133. 根据医疗器械进步协会/欧洲高血压学会/国际标准化组织(ISO 81060-2:2018/Amd.1:202/Amd.2:2024),验证YuWell YE680B自动上臂血压监测仪在儿科和成人人群中的准确性

    Validating the accuracy of the YuWell YE680B automated upper-arm blood pressure monitor in pediatric and adult populations according to the Association for the Advancement of Medical Instrumentation/European Society of Hypertension/International Organization for Standardization (ISO 81060-2:2018/Amd.1:2020/Amd.2:2024).

  134. Firsekibart治疗腹膜透析患者急性痛风发作:病例报告

    Acute gout attack in a peritoneal dialysis patient treated with Firsekibart: a case report.

  135. 溃疡性结肠炎和结肠炎相关癌症的炎症性基质老化

    Inflammatory Stromal Aging in Ulcerative Colitis and Colitis-Associated Cancer.

  136. 一种锰木犀草素共载抗氧化水凝胶,用于协同缓解椎间盘退变中的氧化应激和免疫调节

    A manganese-luteolin co-loaded antioxidant hydrogel for synergistic alleviation of oxidative stress and immunomodulation in intervertebral disc degeneration.

  137. 高脂饮食下γδT细胞在动脉粥样硬化中的作用和机制研究

    Study on the Role and Mechanism of γδ T Cells in Atherosclerosis Under a High-Fat Diet.

  138. 败血症和休克中的高乳酸血症:肾脏代谢的角度

    Hyperlactatemia in sepsis and shock: a renal metabolic perspective.

  139. 数字表型的因果发现框架

    A causal discovery framework for digital phenotyping.

  140. 三种多普勒比值指数预测晚发型胎儿生长受限不良围产期结局的比较

    Comparison of three Doppler ratio indices for predicting adverse perinatal outcomes in late-onset fetal growth restriction.

  141. 靶向乳酸盐-肉桂-葡萄糖摄取轴:隐丹参酮重编程癌症中代谢-表观遗传学串扰

    Targeting the lactate-lactylation-glucose uptake axis: Cryptotanshinone reprograms metabolic-epigenetic crosstalk in gastric cancer.

  142. 推进护理研究中的定性分析:将大型语言模型的文本分析严谨性和效率与访谈数据的人类编码分析进行比较

    Advancing qualitative analysis in nursing research: Comparing text analysis rigor and efficiency of large language models with human-coded analysis for interview data.

  143. 用于评估妊娠期糖尿病和子痫前期胎儿肺发育的多模式深度学习融合模型

    Multimodal deep learning fusion model for assessment of fetal lung development in gestational diabetes mellitus and pre-eclampsia.

  144. 癌症手术患者的循环肿瘤DNA与预后:荟萃分析和试验序列分析

    Circulating tumor DNA and prognosis in gastric cancer patients undergoing surgery: meta-analysis and trial sequential analysis.

  145. 针刺在卒中后运动恢复中的神经可塑性机制:一项随机多模态MRI试验

    Neuroplastic Mechanisms of Acupuncture in Post-Stroke Motor Recovery: A Randomized Multimodal MRI Trial.

  146. 1990-2023年全球肠道传染病、腹泻病和相应病因的负担:2023年全球疾病负担研究的系统分析

    Global burden of enteric infectious diseases, diarrhoeal diseases, and corresponding aetiologies, 1990-2023: a systematic analysis for the Global Burden of Disease Study 2023.

  147. 抗骨质疏松药物对骨折愈合和结果的影响:系统综述和荟萃分析

    The effects of anti-osteoporotic medication on fracture healing and outcomes: a systematic review and meta-analysis.

  148. Handelin通过靶向脂质运载蛋白-2和恢复自噬来抑制NF-κB信号传导,从而抑制破骨细胞生成和骨丢失

    Handelin inhibits osteoclastogenesis and bone loss by targeting lipocalin-2 and restoring autophagy to suppress NF-κB signaling.

  149. [副肿瘤综合征:早期识别和治疗的重要性]

    [Paraneoplastic syndromes: the importance of early recognition and treatment].

  150. 基于人工智能的心脏磁共振微血管阻塞组织学异质性预测主要不良心血管事件:一项多中心研究

    AI-based Histologic Heterogeneity of Microvascular Obstruction at Cardiac MRI for Predicting MACEs: A Multicenter Study.

  151. 儿童和青少年抑郁症患者使用选择性血清素再摄取抑制剂的药物警戒:使用FAERS数据库对血清素不良事件进行不成比例分析

    Pharmacovigilance of SSRIs in Children and Adolescents with Depression: Disproportionality Analysis of Serotonin Adverse Events Using the FAERS Database.

  152. 丹参酮IIA通过调节PTEN和ATP酶抑制因子1抑制小鼠中与结肠炎相关的癌症中的上皮-间充质转变

    Tanshinone IIA Inhibits Epithelial-Mesenchymal Transition in Colitis-Associated Cancer in Mice by Regulating PTEN and ATPase Inhibitory Factor 1.

  153. P38 MAPK通路抑制对炎症期间牙周膜成纤维细胞代谢的影响

    Effects of P38 MAPK Pathway Inhibition on the Metabolism of Periodontal Ligament Fibroblasts During Inflammation.

  154. 在预测新发心脏代谢多发病率方面,估计的葡萄糖处置率优于其他13个胰岛素抵抗指标:来自中国健康与退休纵向研究(CHARLS)的纵向研究和来自全国健康与营养调查(NHANES)的横断面复制

    Estimated glucose disposal rate outperforms thirteen other insulin resistance indices in predicting new-onset cardiometabolic multimorbidity: a longitudinal study from the china health and retirement longitudinal study (CHARLS) and cross-sectional replication from the national health and nutrition examination survey (NHANES).

  155. 每日序贯器官衰竭评估(SOFA)-2分对30天死亡率的预测有效性

    Predictive validity of daily sequential organ failure assessment (SOFA)-2 score for 30-day mortality.

  156. 神经元和星形胶质细胞中干扰素-α/β受体-1的不同和联合缺失会破坏脑能量代谢,并导致帕金森氏痴呆

    Distinct and combined interferon-ɑ/β-receptor-1 loss in neurons and astrocytes disrupt brain energy metabolism and drive Parkinsonian dementia.

  157. 胶质母细胞瘤的肿瘤靶向干扰素-α基因治疗:一项1期试验

    Tumor-targeted interferon-α gene therapy for glioblastoma: a phase 1 trial.

  158. 严重主动脉瓣狭窄患者的循环ACE2水平和ACE I/D多态性

    Circulating ACE2 levels and ACE I/D polymorphism in severe aortic stenosis.

  159. 载银纳米羟基磷灰石/胶原类骨纳米复合材料的制备及其抗菌活性

    Preparation and antibacterial activities of silver nanoparticle-loaded hydroxyapatite/collagen bone-like nanocomposite.

  160. 临床脓毒症表型的多中心验证

    Multicenter Validation of Clinical Sepsis Phenotypes.

  161. 有核梭杆菌通过上调NNMT来调节烟酰胺代谢,以激活大肠杆菌相关癌症中的PARP1/MAPK信号传导

    Fusobacterium nucleatum regulates nicotinamide metabolism via the upregulation of NNMT to activate PARP1/MAPK signalling in colitis-associated cancer.

  162. 使用综合生物信息学分析破译皮肤利什曼病全身表现的分子基础

    Deciphering the Molecular Basis of Systemic Manifestations in Cutaneous Leishmaniasis Using Integrated Bioinformatics Analysis.

  163. 间质性肺病与STING通路

    Interstitial lung disease and the STING pathway.

  164. 远程缺血预处理和后处理减少了调节炎症反应和代谢途径的脑缺血损伤

    Remote ischemic perconditioning and postconditioning reduced cerebral ischemic injury modulating inflammatory responses and metabolic pathways.

  165. Ivonescimab联合化疗与tislelizumab联合化疗治疗晚期鳞状非小细胞肺癌(HARMONi-6):中国一项随机、双盲、3期试验的中期总生存率分析

    Ivonescimab plus chemotherapy versus tislelizumab plus chemotherapy in advanced squamous non-small-cell lung cancer (HARMONi-6): interim overall survival analysis of a randomised, double-blind, phase 3 trial in China.

  166. 制备用于化学机械抛光的稳定氧化铝悬浮液

    Preparation of Stable Alumina Suspensions for Chemical Mechanical Polishing.

  167. 同时发生的单形性嗜上皮性肠道T细胞淋巴瘤伴异常CD20表达与肺腺癌:一例病例报告及文献综述

    Concurrent monomorphic epitheliotropic intestinal T-cell lymphoma with aberrant CD20 expression and lung adenocarcinoma: A case report and literature review.

  168. 共同发生的精神疾病和内分泌、代谢和营养疾病的患病率和结果:基于对254154533份记录的总体审查的图谱

    Prevalence and outcomes of co-occurring psychiatric and endocrine, metabolic, and nutritional disorders: An atlas based on umbrella review of 254,154,533 records.

  169. 预防心力衰竭

    Prevention of heart failure.

  170. 血栓形成生物标志物:在重症肺炎早期诊断和预后中的应用价值

    Thrombosis biomarkers: utility in early diagnosis and prognosis of severe pneumonia.

  171. 环境颗粒物和极端天气事件对关节炎风险的协同作用:一项前瞻性队列研究

    Synergistic effects of ambient particulate matter and extreme weather events on arthritis risk: a prospective cohort study.

  172. AARS1通过重新连接Akt和NF-κB信号传导来抑制自噬和维持炎症,从而促进糖尿病肾病

    AARS1 promotes diabetic kidney disease through rewiring Akt and NF-κB signaling to suppress autophagy and sustain inflammation.

  173. 早期肠道微生物群与过敏性疾病:免疫调节机制和干预进展

    Early-life Gut Microbiota and Allergic Diseases: Immune Regulatory Mechanisms and Intervention Progress.

  174. 成纤维细胞生长因子-18(FGF-18)通过抑制TRIM28减轻ox-LDL诱导的内皮炎症和单核细胞粘附

    Fibroblast Growth Factor-18 (FGF-18) Attenuates ox-LDL-Induced Endothelial Inflammation and Monocyte Adhesion by Inhibiting TRIM28.

  175. IER3作为RFX5转录共激活因子,通过AKR1B10介导的p53转录调控促进肝细胞癌的进展

    IER3 as an RFX5 transcriptional co-activator promotes hepatocellular carcinoma progression via AKR1B10-mediated p53 transcriptional regulation.

  176. 除了减肥:肥胖药物的多系统益处

    Beyond weight loss: multisystem benefits of obesity medications.

  177. 阿尔茨海默病

    Alzheimer's disease.

  178. 人工智能驱动的膀胱镜诊断支持系统:多架构深度学习模型的临床应用

    Artificial Intelligence-Powered Cystoscopy Diagnostic Support System: Clinical Application of Multiarchitecture Deep Learning Models.

  179. 携带致病性KRAS突变并表达ER、PR和CD10的子宫粘液样炎性肌纤维母细胞肉瘤(MIMS)

    Uterine Myxoid Inflammatory Myofibroblastic Sarcoma (MIMS) Harboring Pathogenic KRAS Mutations and Expressing ER, PR, and CD10.

  180. 微塑料暴露通过肠心轴在血流动力学应激下加重心肌病

    Microplastic Exposure Aggravates Cardiomyopathy Under Hemodynamic Stress Through the Gut-Heart Axis.

  181. 2型糖尿病患者的生活质量和自我调节疲劳:个人掌握和健康促进行为的中介作用

    Quality of life and self-regulatory fatigue in patients with type 2 diabetes mellitus: the mediating effects of personal mastery and health-promoting behaviors.

  182. 严格定义的溃疡性结肠炎相关肿瘤内镜切除术后的长期结果:一项探索性回顾性队列研究

    Long-Term Outcomes After Endoscopic Resection for Strictly Defined Ulcerative Colitis-Associated Neoplasia: An Exploratory Retrospective Cohort Study.

  183. 食管胃交界癌患者经纵隔食管切除术的疗效

    Outcomes of transmediastinal esophagectomy for patients with esophagogastric junction cancers.

  184. 细菌氧化应激的生理生化

    The physiology and biochemistry of oxidative stress in bacteria.

  185. 脂多糖结合蛋白作为坏死性小肠结肠炎诊断的生物标志物

    Lipopolysaccharide-binding protein as a biomarker in the diagnosis of necrotizing enterocolitis.

  186. 在HER2-阳性的胃食管癌症中,扎尼他单抗与Tislelizumab的联合用药和不联合用药

    Zanidatamab with and without Tislelizumab in HER2-Positive Gastroesophageal Cancer.

  187. 休眠转换的多组学解析揭示了硅藻假微型海链藻休眠细胞长期存活的机制

    Multi-omics dissection of dormancy transition reveals mechanisms underlying long-term survival in the diatom Thalassiosira pseudonana resting cells.

  188. CNS1依赖性调节性T细胞从急性肺损伤中恢复

    CNS1-dependent regulatory T cells shape recovery from acute lung injury.

  189. 生物治疗持续时间对中重度银屑病无药物缓解的影响:一项回顾性队列研究

    Impact of Biologic Treatment Duration on Drug-Free Remission in Moderate-to-Severe Psoriasis: A Retrospective Cohort Study.

  190. 败血症的快速微生物诊断:当前和前瞻性方法的叙述性综述

    Rapid Microbiological Diagnostics for Sepsis: Narrative Review of Current and Prospective Approaches.

  191. 【细胞外囊泡在重症肺炎中的应用研究进展】

    [Research progress on the application of extracellular vesicle in severe pneumonia].

  192. 自体动静脉瘘(AVF)成熟的围手术期手术和麻醉预测因素:回顾性队列分析

    Peri-Operative Surgical and Anaesthetic Predictors of Autogenous Arteriovenous Fistula (AVF) Maturation: A Retrospective Cohort Analysis.

  193. 维持性血液透析患者血钴水平与动静脉瘘功能障碍的关系:一项多中心观察研究

    Association Between Blood Cobalt Levels and Arteriovenous Fistula Dysfunction in Patients Undergoing Maintenance Hemodialysis: A Multicenter Observational Study.

  194. 用于预测胸腰椎骨质疏松性椎体骨折的深度学习辅助放射学

    Deep Learning-Assisted Radiomics for Predicting Thoracolumbar Osteoporotic Vertebral Fractures.

  195. 根据基于测量的护理,住院青少年的症状有所改善

    Symptoms Improve for Inpatient Adolescents According to Measurement-Based Care.

  196. {"_":"通过抗氧化和MAPK/NF-κB介导的抗炎机制对乙醇/盐酸诱导的胃损伤的保护作用。","i":["荔枝草"]}

    {"_":"Gastroprotective Effects of via Antioxidant and MAPK/NF-κB-Mediated Anti-Inflammatory Mechanisms in Ethanol/HCl-Induced Gastric Injury.","i":["Salvia plebeia"]}

  197. 在人支气管肺泡癌细胞系NCI-H358中,一种高分子量的Planarian粘液触发了与UPR相关的细胞死亡途径

    A High-Molecular-Weight Fraction of Planarian Mucus Triggers UPR-Linked Cell Death Pathway in Human Bronchioalveolar Carcinoma Cell Line NCI-H358.

  198. 通过综合多组学和基于网络的方法揭示肝细胞癌背后的预后生物标志物

    Uncovering Prognostic Biomarkers Underlying Hepatocellular Carcinoma Through Integrative Multi-Omics and a Network-Based Approach.

  199. 济州本地人和移民胆囊息肉的患病率和危险因素:回顾性横断面研究

    Prevalence and Risk Factors of Gallbladder Polyps Among Jeju Natives and Migrants: Retrospective Cross-Sectional Study.

  200. 慢性血液透析患者的症状群和纵向进展:一项前瞻性单中心研究

    Symptom Clusters and Longitudinal Progression in Chronic Hemodialysis Patients: A Prospective Single-Center Study.

  201. 接受血液透析的动静脉瘘患者的生活经历:一项现象学研究

    Lived Experiences of Women with Arteriovenous Fistula Undergoing Hemodialysis: A Phenomenological Study.

  202. Mcl1作为连接炎症性肠病与结直肠肿瘤发生的分子开关

    Mcl1 as a Molecular Switch Linking Inflammatory Bowel Diseases to Colorectal Tumorigenesis.

  203. 从肠道稳态到大肠癌癌症:微生物肌苷信号的时空重编程

    From Gut Homeostasis to Colorectal Cancer: Spatial and Temporal Reprogramming of Microbial Inosine Signaling.

  204. CRISPR/Cas9工程Celegans长QT综合征模型中hERG孔结构域错义变体的运输和功能影响的体内分析

    In vivo analysis of trafficking and functional impact of hERG pore-domain missense variants in a CRISPR/Cas9-engineered Celegans model of long QT syndrome.

  205. FGFR2b蛋白过度表达在晚期癌症和胃食管交界癌中的全球流行率:两项贝马单抗III期研究的汇总分析

    Global prevalence of FGFR2b protein overexpression in advanced gastric cancer and gastroesophageal junction cancers: pooled analysis of two bemarituzumab phase III studies.

  206. NEFL⁺NEFM⁺ 髓系重编程细胞通过CX3CL1-CX3CR1介导的Tregs趋化性促进ccRCC的进展

    NEFL⁺NEFM⁺ myeloid-reprogrammed cells promote ccRCC progression through CX3CL1-CX3CR1-mediated Tregs chemotaxis.

  207. 加工低蛋白糙米对慢性肾病患者的影响

    Effects of processed low-protein brown rice on patients with chronic kidney disease.

  208. 阿联酋医院护士自我报告的数字健康素养和工作参与度

    Self-Reported Digital Health Literacy and Work Engagement Among Nurses in UAE Hospitals.

  209. 重新审视肝纤维化中的Wnt/β-Catenin信号传导:CBP和p300对转录状态的调控

    Reframing Wnt/β-Catenin Signalling in Liver Fibrosis: Transcriptional State Regulation by CBP and p300.

  210. 29000名患者JAK-STAT抑制剂感染风险的大规模荟萃分析

    Large-scale meta-analysis of infection risk with JAK-STAT inhibitors in 29,000 patients.

  211. 运动激素鸢尾素通过清除功能失调的线粒体来缓解类风湿性关节炎

    Exercise hormone irisin alleviates rheumatoid arthritis by removing dysfunctional mitochondria.

  212. 1类DISARM系统限制了肺炎克雷伯菌序列类型23中结合碳青霉烯酶编码质粒

    Class 1 DISARM system in restriction of conjugative carbapenemase-encoding plasmids in Klebsiella pneumoniae sequence type 23.

  213. 心肾共病患者容量管理的最佳证据总结

    Best Evidence Summary for Volume Management of Patients With Heart and Kidney Comorbidity.

  214. 乳腺动脉钙化作为未来心血管事件和死亡率的预测因素:系统综述和荟萃分析

    Breast Arterial Calcification as a Predictor for Future Cardiovascular Events and Mortality: A Systematic Review and Meta-analysis.

  215. 使用纳米孔自适应采样对严重发热伴血小板减少综合征病毒进行全基因组测序

    Whole-genome sequencing of severe fever with thrombocytopenia syndrome virus using nanopore adaptive sampling.

  216. 来自补肾活血方(BSHXF)的桃叶珊瑚苷和丹参醇通过影响髓核细胞改善椎间盘退变

    Aucubin and Tanshinol from Bu-Shen-Huo-Xue-Fang (BSHXF) improve intervertebral disc degeneration through affecting nucleus pulposus cell.

  217. 杜伐单抗联合安洛替尼与单独使用杜伐单抗作为扩展性小细胞肺癌的维持治疗(DURABLE):一项多中心、随机、II期试验和生物标志物分析

    Durvalumab plus anlotinib versus durvalumab alone as maintenance treatment in extensive-stage small-cell lung cancer (DURABLE): a multicenter, randomized, phase II trial and biomarker analysis.

  218. 一项由护士主导的针对血液透析终末期肾病成年人的足部护理教育干预:一项试点定量研究

    A nurse-led foot care educational intervention for adults with end-stage kidney disease on haemodialysis: A pilot quantitative study.

  219. 食用菌复方虫草素可预防对乙酰氨基酚引起的肝损伤

    Edible Fungus Compound Cordycepin Protects Against Acetaminophen-Induced Liver Injury.

  220. 与严重发热伴血小板减少综合征发生相关的环境因素的系统综述

    Systematic review of environmental factors associated with severe fever with thrombocytopenia syndrome occurrences.

  221. 严重发烧伴血小板减少综合征病毒从狗传播给家庭中的人类和猫

    Transmission of severe fever with thrombocytopenia syndrome virus from a dog to humans and a cat in a household cluster.

  222. 肠道-骨轴串扰:微生物驱动的免疫代谢神经网络在骨疾病和精确干预中的应用

    Gut-bone axis crosstalk: Microbiota-driven immune-metabolic-neural networks in bone disorders and precision interventions.

  223. 热响应型水净化:一种用于在农业废弃物滤料上精准构建抗菌ZnO的热切换分子刷

    Thermo-responsive water purification: a thermo-switchable molecular brush for precision engineering of antibacterial ZnO on agro-waste filters.

  224. 前交叉韧带(ACL)损伤运动员并发软骨损伤的治疗选择

    Treatment options for concomitant cartilage damage in the anterior cruciate ligament (ACL)-injured athlete.

  225. 基于机器学习的慢性阻塞性肺疾病急性加重期ICU患者多药耐药性风险预测模型的构建和内外验证

    Construction and internal-external validation of a machine learning-based risk prediction model for multidrug resistance in ICU patients with acute exacerbation of chronic obstructive pulmonary disease.

  226. 病例报告:Ivarmacitinib治疗难治性原发性皮肤淀粉样变

    Case Report: Ivarmacitinib in the treatment of refractory primary cutaneous amyloidosis.

  227. 妊娠期便秘和肠道微生物群:机制、干预措施及其对母婴健康的影响

    Gestational constipation and the gut microbiota: mechanisms, interventions, and implications for maternal and offspring health.

  228. 抗酸剂滥用——一例牛奶碱综合征

    Antacid Abuse - A Case of Milk-Alkali Syndrome.

  229. β-内酰胺酶抑制剂临床应用和发展综述:机制、谱和治疗应用

    {"_":"A Review of -Lactamase Inhibitors in Clinical Use and Development: Mechanisms, Spectrum, and Therapeutic Applications.","i":["β"]}

  230. 工程纳米药物触发ROS风暴,用于增强癌症治疗

    Engineered nanomedicine triggering ROS storms for enhanced cancer therapeutics.

  231. 慢性乙型肝炎的功能性治疗对肝细胞癌预防的影响:证据和临床意义

    Functional cure for chronic hepatitis B on hepatocellular carcinoma prevention: Evidence and clinical implications.

  232. 日本两个相邻流行县野猪感染严重发热伴血小板减少综合征病毒的血清学和分子评估

    Serological and molecular assessment of severe fever with thrombocytopenia syndrome virus infection in wild boars from two adjacent endemic prefectures in Japan.

  233. p53在帕金森病中调节线粒体功能和α-突触核蛋白聚集

    p53 regulates mitochondrial function and alpha-synuclein aggregation in Parkinson's disease.

  234. 基于TriNetX的队列研究表明,骨质疏松患者全肩关节置换术或逆行肩关节置换后,术后双膦酸盐治疗与较低的假体相关并发症有关

    Postoperative bisphosphonate therapy is associated with lower prosthesis-related complications after total or reverse shoulder arthroplasty in osteoporotic patients: a TriNetX-based cohort study.

  235. 经颅聚焦超声神经调控治疗创伤后应激障碍:新证据和突出挑战

    Transcranial focused ultrasound neuromodulation for post-traumatic stress disorder: Emerging evidence and outstanding challenges.

  236. 对炎症性乳腺癌症的免疫景观进行重新编程

    Reprogramming the Immune Landscape of Inflammatory Breast Cancer.

  237. 将Grad CAM扩展到DualNet

    Extending Grad-CAM to DualNet.

  238. 利血平诱导的小鼠抑郁症模型的开发和表征:一种综合的体内和计算机方法

    Development and characterization of a reserpine-induced mouse model of depression: An integrated in-vivo and in-silico approach.

  239. 子痫前期的病理生理学

    The pathophysiology of pre-eclampsia.

  240. 血液多组学揭示了与晚期肝硬化结果相关的脂质介质线粒体网络失调

    Blood multiomics reveal a dysregulated lipid mediator-mitochondrial network associated with the outcome of advanced cirrhosis.

  241. 聚乙二醇化重组非αIL-2培根利白素与西米普利单抗治疗晚期不可切除或转移性皮肤癌的1/2期研究

    Phase 1/2 study of pegenzileukin, a pegylated recombinant non-alpha IL-2, with cemiplimab for the treatment of advanced unresectable or metastatic skin cancers.

  242. 参灵降脂方通过NF-κB/NLRP3途径抑制血管炎症,减轻ApoE-/-小鼠动脉粥样硬化

    {"_":"Shenling Jiangzhi formula alleviates atherosclerosis in ApoE mice by inhibiting vascular inflammation via the NF-κB/NLRP3 pathway.","sup":["-/-"]}

  243. 甘草棘球蛋白对蜡样芽孢杆菌具有抗菌和抗生物膜作用:机制及其在牛奶保鲜中的应用

    Echinatin from licorice exhibits antibacterial and anti-biofilm effects against Bacillus cereus: Mechanism and application in milk preservation.

  244. 基于HPLC指纹图谱、化学计量学和网络药理学对结核菌质量标志物的综合分析

    Comprehensive Analysis of Quality Markers in Speranskia tuberculata based on HPLC Fingerprinting, Chemometrics, and Network Pharmacology.

  245. 乳酸菌和粘蛋白丝菌:在炎症性肠病和结直肠癌癌症中的新作用

    Lactate and <italic>Akkermansia muciniphila</italic>: Emerging Roles in Inflammatory Bowel Disease and Colorectal Cancer.

  246. 常染色体显性Alport综合征

    Autosomal Dominant Alport Syndrome.

  247. 气候风险、基础设施脆弱性和老龄化:克什米尔老年人经历的定性研究(印度)

    Climatic Risk, Infrastructural Fragility and Ageing: A Qualitative Study of Older Adults' Experiences in Kashmir (India).

  248. CKD患者透析前和透析阶段的自我管理意图和行为:基于保护动机理论的横断面研究

    Self-Management Intentions and Behaviors Among CKD Patients at Predialysis and Dialysis Stages: A Cross-Sectional Study Based on Protection Motivation Theory.

  249. 灵芝多糖通过调节去卵巢小鼠的肠道菌群来改善肝脏代谢紊乱

    {"_":" polysaccharides improve liver metabolic disorders by modulating gut microbiota of ovariectomized mice.","i":["Ganoderma lucidum"]}

  250. 织物增强仿生细胞迁移高速公路:微孔引导和血管无细胞基质调节,用于原位血管修复

    Fabric-reinforced biomimetic cell migration highway: Micropore guidance and vascular acellular matrix regulation for in situ vascular repair.

  251. 1990-2023年全球精神障碍患病率和负担的最新趋势:2023年全球疾病负担研究的系统分析

    Updated trends in the global prevalence and burden of mental disorders, 1990-2023: a systematic analysis for the Global Burden of Disease Study 2023.

  252. 异质风车形微型机器人的微纳架构,具有磁光热协同作用,可加速货物运输

    Micro-nanoarchitectonics of heterogeneous windmill-shaped microrobots with magneto-photothermal synergy for accelerated cargo delivery.

  253. Sauchinone通过激活皮肤成纤维细胞中的Keap1-Nrf2通路来抑制氧化应激和铁下垂,从而减轻UVB诱导的光老化

    Sauchinone attenuates UVB-induced photoaging by suppressing oxidative stress and ferroptosis through activation of the Keap1-Nrf2 pathway in dermal fibroblasts.

  254. 经口前庭内镜甲状腺切除术与开放手术治疗单侧甲状腺恶性肿瘤的疗效

    Efficacy of transoral vestibular endoscopic thyroidectomy versus open surgery in the treatment of unilateral thyroid malignancies.

  255. 电阻抗断层扫描检测肺栓塞灌注缺陷的准确性

    Accuracy of electrical impedance tomography to detect perfusion defects in pulmonary embolism.

  256. 重度抑郁症患者线粒体DNA变异与肠道微生物组之间的复杂相关性:全基因组关联分析

    Complex correlations between mitochondrial DNA variants and gut microbiome in major depressive disorder: a genome-wide association analysis.

  257. 术前抗重塑骨质疏松治疗与假体周围肱骨骨折风险增加有关

    Preoperative anti-remodeling osteoporotic therapy is associated with increased periprosthetic humeral fracture risk.

  258. CaWRKY8通过负调控防御相关基因的表达参与辣椒对辣椒轻度斑驳病毒的防御反应

    CaWRKY8 participates in the defense response of pepper to pepper mild mottle virus by negatively regulating the expression of defense-related genes.

  259. 减轻慢性肾病患者非正式护理人员负担的干预措施:系统综述和荟萃分析

    Interventions to Reduce Burden Among Informal Caregivers of People With Chronic Kidney Disease: Systematic Review and Meta-Analysis.

  260. 高压氧治疗在微生物感染相关疾病中的辅助作用

    The Adjunctive Role of Hyperbaric Oxygen Therapy in Microbial Infection-Related Conditions.

  261. 小儿阑尾切除术后残留的Hem-o-lok®夹子引起的慢性疼痛:手术切除的必要条件

    {"_":"Chronic pain from retained Hem-o-lok clips after pediatric appendectomy: the imperative for surgical removal.","sup":["®"]}

  262. 氟伏沙明调节免疫细胞系中的干扰素和炎症基因特征:狼疮再利用的计算机转录组学分析

    {"_":"Fluvoxamine modulates interferon and inflammatory gene signatures in immune cell lines: an transcriptomic analysis for lupus repurposing.","i":["in silico"]}

  263. 心力衰竭和衰老临床前模型中心脏脆弱性的评估——发现与临床之间的平行关系

    Assessment of Cardiac Frailty in Preclinical Models of Heart Failure and Ageing - Parallels Between Discovery and the Clinic.

  264. 在健全和截肢者人群中,基于sEMG的手运动学解码的生理感知潜在移位适应

    Physiology-aware latent shift adaptation for sEMG-based hand kinematics decoding across able-bodied and amputee populations.

  265. 突触素自身抗体介导小脑性共济失调的突触功能障碍

    Synaptophysin autoantibodies mediate synaptic dysfunction in cerebellar ataxia.

  266. 光声成像显示子痫前期小鼠模型中胎盘氧饱和度保持不变

    Optoacoustic imaging reveals preserved placental oxygen saturation in a mouse model of preeclampsia.

  267. 大气阻塞事件的时空探测和不确定性可视化

    Spatiotemporal Detection and Uncertainty Visualization of Atmospheric Blocking Events.

  268. suPAR在肾损伤进展中的作用

    The Role of suPAR in Kidney Injury Progression.

  269. 体外膜肺氧合对危重患者抗菌药物暴露的影响:一项前瞻性观察性研究

    Impact of extracorporeal membrane oxygenation on antimicrobial exposure in critically ill patients: a prospective observational study.

  270. 人工智能辅助综合护理促进中国结肠镜检查(AICC)的采用:集群随机对照试验的研究方案

    Artificial intelligence-assisted integrated care to promote colonoscopy uptake (AICC) in China: study protocol for a cluster randomized controlled trial.

  271. 源自粪肠球菌的细胞外囊泡:炎症激活不依赖于内化作用

    Extracellular vesicles derived from Enterococcus faecalis: inflammatory activation does not require internalization.

  272. 冷冻活检与支气管镜肺活检钳:FROSTBIE-2随机临床试验

    Cryobiopsy vs Forceps for Bronchoscopic Lung Biopsy: The FROSTBITE-2 Randomized Clinical Trial.

  273. 组织修复中的代谢转变窗口:时机、边界条件与消退

    Metabolic Transition Windows in Tissue Repair: Timing, Boundary Conditions and Resolution.

  274. 病例报告:严重免疫相关心脏毒性后晚期PD-L1高鳞状细胞肺癌的长期存活率

    Case Report: Long-term survival in advanced PD-L1-high squamous cell lung cancer following severe immune-related cardiotoxicity.

  275. 心肌功能指数和多普勒参数在检测妊娠合并高血压疾病胎儿生长受限中的诊断价值

    Diagnostic value of the myocardial performance index and doppler parameters in detecting fetal growth restriction in pregnancies complicated by hypertensive disorders.

  276. 综合系统生物学和实验验证揭示了GALNT14作为脓毒症的新型诊断生物标志物和治疗靶点

    Integrative Systems Biology and Experimental Validation Unveil GALNT14 as a Novel Diagnostic Biomarker and Therapeutic Target for Sepsis.

  277. 配对单细胞分析揭示骨肉瘤的化疗耐药性

    Paired single cell analysis reveals chemotherapy resistance in osteosarcoma.

  278. 用于计算机断层扫描造影剂外渗检测的可解释知识引导算法

    Explainable Knowledge-Guided Algorithm for Contrast Extravasation Detection on Computed Tomography.

  279. 极端条件下的皮肤检查

    Skin examination in extreme conditions.

  280. 一种基于双联MIRA-LFD测定的牛PRNP基因indel多态性的快速视觉检测方法

    A rapid visual detection method for indel polymorphisms in the bovine PRNP gene based on a duplex MIRA-LFD assay.

  281. Nerandomilast治疗特发性肺纤维化和进行性肺纤维化:临床疗效、安全性和治疗位置

    Nerandomilast for Idiopathic Pulmonary Fibrosis and Progressive Pulmonary Fibrosis: Clinical Efficacy, Safety, and Place in Therapy.

  282. METTL3通过METTL3/IGF2BP3/MTA1/PI3K/AKT轴促进膀胱癌症的进展

    METTL3 promotes the progression of bladder cancer through the METTL3/IGF2BP3/MTA1/PI3K/AKT axis.

  283. 基于介孔聚多巴胺的仿生纳米递送系统:精准治疗的最新进展

    Mesoporous polydopamine-based biomimetic nanodelivery systems: recent advances in precision therapy.

  284. 衰老过程中运动诱导认知保护的新机制:D-氨基酸氧化酶/D-丝氨酸依赖性NMDAR信号调节

    A novel mechanism of exercise-induced cognitive protection in ageing: D-amino acid oxidase /D-serine-dependent modulation of NMDAR signalling.

  285. 基于深度学习的双域重建,用于呼吸门控肺SBRT中的不间断门控CBCT

    Deep learning-based dual-domain reconstruction for nonstop gated CBCT in respiratory gating lung SBRT.

  286. Dupilumab阻断IL-4/IL-13对2型炎症性疾病微生物组的影响:系统综述

    Impact of IL-4/IL-13 Blockade with Dupilumab on the Microbiome in Type 2 Inflammatory Diseases: A Systematic Review.

  287. 多囊卵巢综合征啮齿动物模型中kisspeptin/GnRH调节的神经递质和神经调节剂失衡及其对心理健康障碍的影响:系统综述

    Neurotransmitter and neuromodulator imbalance in kisspeptin/GnRH regulation in rodent models of polycystic ovary syndrome and its implications for mental health disorders: A systematic review.

  288. 近视和间歇性外斜视儿童的角膜塑形术:南京斜视队列

    Orthokeratology in children with myopia and intermittent exotropia: the Nanjing strabismus cohort.

  289. 肿瘤微环境中的cGAS STING信号:对免疫监测和治疗策略的影响

    cGAS-STING Signalling in the tumour microenvironment: Implications for immune surveillance and therapeutic strategies.

  290. 全膝关节置换术中的现代非骨水泥髌骨表面置换术与残余骨厚度的早期并发症发生率低有关

    Contemporary cementless patellar resurfacing in total knee arthroplasty is associated with a low early complication rate across residual bone thicknesses.

  291. 透析内蹬踏运动对透析充分性的影响:一项随机对照试验

    Effect of intra-dialytic pedaling exercise on dialysis adequacy: A randomized controlled trial.

  292. 采用直接反馈对齐的大规模现代深度学习架构的简化光学训练

    Streamlined optical training of large-scale modern deep learning architectures with direct feedback alignment.

  293. 揭示胶质母细胞瘤中强化干性和免疫抑制的反馈回路

    Uncovering a feedback loop in glioblastoma that reinforces stemness and immunosuppression.

  294. SFRT联合免疫治疗胰腺腺泡细胞癌大体积肝转移:病例报告

    SFRT combined with immunotherapy for bulky hepatic metastasis from pancreatic acinar cell carcinoma: a case report.

  295. 护士的数字素养、心理韧性和工作压力:病房环境的调节作用

    Digital literacy, psychological resilience, and work stress among nurses: the moderating role of ward environment.

  296. 聚乙二醇干扰素α治疗产后妇女慢性乙型肝炎病毒感染的疗效:一项多中心前瞻性研究

    Efficacy of pegylated interferon alpha in treating postpartum women with chronic hepatitis B virus infection: a multicenter prospective study.

  297. 整合多组学、孟德尔随机化和实验验证,揭示中药在绝经后骨质疏松症中的作用

    Integrating Multi-omics, Mendelian Randomization, and Experimental Validation to Unveil the Role of Traditional Chinese Medicine in Postmenopausal Osteoporosis.

  298. 使用无监督机器学习对先兆子痫进行表型分析:一项前瞻性队列研究

    Phenotyping Preeclampsia Using Unsupervised Machine Learning: A Prospective Cohort Study.

  299. 软骨下骨髓穿刺浓缩液注射改善膝骨性关节炎的临床结果并减少骨髓损伤:12个月的回顾性分析

    Subchondral bone marrow aspirate concentrate injection improves clinical outcomes and reduces bone marrow lesions in knee osteoarthritis: 12-month retrospective analysis.

  300. ALS中的单细胞和空间转录组综合分析揭示了外周到中心的免疫浸润和重编程

    Integrated single-cell and spatial transcriptomic profiling in ALS uncovers peripheral-to-central immune infiltration and reprogramming.

  301. 组织刚性相变形成形态发生梯度

    Tissue rigidity phase transition shapes morphogen gradients.

  302. 全膝关节置换术后胫骨假体周围骨折的危险因素:固定和植入物设计的影响

    Risk Factors for Tibial Periprosthetic Fractures After Total Knee Arthroplasty: The Influence of Fixation and Implant Design.

  303. 神经可塑性是双向的:通过力量训练来对抗与年龄相关的神经退化

    Neural plasticity is a two-way street: Counteracting age-related neural deterioration with strength training.

  304. 2025年国际炎症性乳腺癌症研讨会的科学亮点和观点

    Scientific highlights and perspectives from the International Inflammatory Breast Cancer Symposium 2025.

  305. 综合转录组学、分子对接和孟德尔随机化分析揭示了肾脏缺血再灌注损伤中的微生物丙酸JUN通路

    Integrated transcriptomic, molecular docking, and mendelian randomization analysis reveal a microbial-propionate-JUN pathway in renal ischemia-reperfusion injury.

  306. 年轻人和老年人的运动功能和非周期性皮层电活动

    Mobility Function and Aperiodic Electrocortical Activity in Younger and Older Adults.

  307. 胎儿脐动脉和大脑中动脉的彩色多普勒超声参数有助于诊断妊娠期高血压疾病和评估高龄产妇的严重程度

    Color Doppler Ultrasound Parameters of Fetal Umbilical Artery and Middle Cerebral Artery Assist in Diagnosing Hypertensive Disorder of Pregnancy and Evaluating the Severity in Women of Advanced Maternal Age.

  308. 巨噬细胞转分化为肌成纤维细胞通过MERTK-SPP1-SRC-TKS5信号轴参与肺纤维化

    Macrophage-to-Myofibroblast Transdifferentiation Contributes to Pulmonary Fibrosis via the MERTK-SPP1-SRC-TKS5 Signaling Axis.

  309. 抑郁症状与糖尿病、慢性肾病和晚年体力活动的关系

    Associations of Depressive Symptoms With Diabetes, Chronic Kidney Disease, and Physical Activity in Later Life.

  310. 近视儿童干眼病风险预测模型的开发和验证

    Development and validation of a risk prediction model for dry eye disease in myopic children.

  311. 整合网络药理学和实验验证策略,研究药用和食用柑橘植物对抗阿尔茨海默病的机制和关键黄酮类化合物

    Integrating network pharmacology and experimental validation strategies to investigate the mechanisms and key flavonoids in medicinal and edible citrus plants against Alzheimer's disease.

  312. 围手术期右美托咪啶鼻喷雾剂改善胸腔镜肺手术患者的术后睡眠:一项前瞻性随机对照试验

    Perioperative dexmedetomidine nasal spray improves postoperative sleep in patients undergoing thoracoscopic lung surgery: a prospective, randomized controlled trial.

  313. 纳米传感器中的死亡密码:外泌体调节程序性细胞死亡的机制和进展

    The death code in nanomessengers: Mechanisms and advances in the regulation of programmed cell death by exosomes.

  314. 三七加工驱动的化学转化和药理学变化

    Processing-driven chemical transformations and pharmacological shifts in Panax notoginseng.

  315. 马来西亚的沙门氏菌:爆发、污染源、血清型分布和抗菌素耐药性模式

    Salmonella in Malaysia: Outbreaks, contamination sources, serovar distribution and antimicrobial resistance patterns.

  316. 危重肥胖患者的气道管理

    Airway management in critically ill patients with obesity.

  317. 双尺度脂质体组装使高海拔肺水肿和急性肺损伤中的肺泡巨噬细胞靶向基因递送成为可能

    Dual-Scale Liposomal Assembly Enables Alveolar Macrophage-Targeted Gene Delivery in High-Altitude Pulmonary Edema and Acute Lung Injury.

  318. 冠状动脉旁路移植术后的二级预防:2026年更新:美国心脏协会的科学声明

    Secondary Prevention After Coronary Artery Bypass Graft Surgery: 2026 Update: A Scientific Statement From the American Heart Association.

  319. 没食子酸通过调节肠道微生物群和抑制NF-κB/MAPK信号通路的激活来预防DSS诱导的结肠炎

    Gallic Acid Protects Against DSS-Induced Colitis by Modulating Gut Microbiota and Suppressing the Activation of NF-κB/MAPK Signaling Pathway.

  320. 线粒体作为细胞稳态和应激反应的综合枢纽

    Mitochondria as an Integrative Hub of Cellular Homeostasis and Stress Response.

  321. 匈牙利癌症患者门诊姑息治疗后的症状改善和相关的ESAS领域。

    Symptom Improvement and Interrelated ESAS Domains Following Outpatient Palliative Care in Hungarian Cancer Patients.

  322. 冬油菜较低的抽薹高度提高了其对冷胁迫的耐受性和对北方干旱寒冷地区的适应性

    {"_":"Lower Bolting Height of Winter Rapeseed ( L.) Enhances Cold Stress Tolerance and Adaptability to Arid-Frigid Regions in Northern China.","i":["Brassica napus"]}

  323. 肺脑轴介导经鼻给药的唾液酸乳杆菌及其EV递送的代谢产物在血管性痴呆中的神经保护作用

    The lung-brain axis mediates the neuroprotective effects of nasally administered L. salivarius and its EV-delivered metabolite in vascular dementia.

  324. 柠檬酸协同羧甲基壳聚糖/生物活性玻璃矿化膜:牙本质仿生矿化、促进结合和抗菌性能

    Citric acid synergized carboxymethyl chitosan/bioactive glass mineralizing film: Dentin biomimetic mineralization, bonding promotion and antibacterial performance.

  325. 具有病理侵袭性特征的非小细胞肺癌的节段切除术与肺叶切除术:多中心3期试验JCOG0802/WJOG4607L的事后补充分析

    Segmentectomy Versus Lobectomy in NSCLC With Pathologically Invasive Features: A Post Hoc Supplementary Analysis of Multicenter, Phase 3 Trial JCOG0802/WJOG4607L.

  326. 多囊卵巢综合征的新名称:多内分泌代谢性卵巢综合征:一个多步骤的全球共识过程

    Polyendocrine metabolic ovarian syndrome, the new name for polycystic ovary syndrome: a multistep global consensus process.

  327. 急性呼吸窘迫儿童的氧饱和度阈值(OxyKids):一项多中心、开放、平行组、随机临床试验

    Oxygen saturation thresholds in children with acute respiratory distress (OxyKids): a multicentre, open, parallel-group, randomised clinical trial.

  328. 乳腺癌精准医疗中多维靶向探针的研究进展

    Advances in multi-dimensional targeting probes for precision medicine of breast cancer.

  329. 有限元分析指导的气泡微针协同设计:控制尖端分离,实现快速经皮和舌下给药

    FEA-guided co-design of bubble microneedles: controlled tip separation for rapid transdermal and sublingual delivery.

  330. 初步角妊娠的临床结果和实际管理意义:系统综述和汇总分析(2010-2025)

    Clinical outcomes and practical management implications in rudimentary horn pregnancies: a systematic review and pooled analysis (2010-2025).

  331. 脑耐力训练调节结构-功能耦合并提高足球专项表现:多模态MRI研究

    Brain Endurance Training Modulates Structure-Function Coupling and Enhances Soccer-Specific Performance: A Multimodal MRI Study.

  332. 探索零透视前沿:电生理手术中的当前工具、证据与未来方向

    Navigating the Zero Fluoroscopy Frontier: Current Tools, Evidence and Future Directions in Electrophysiology Procedures.

  333. 依从性和遗传变异性是高海拔地区补充l-精氨酸/l-瓜氨酸成功的决定因素——一项试点研究

    Compliance and Genetic Variability Are Determinants of the Success of l-Arginine/l-Citrulline Supplementation in High Altitude-A Pilot Study.

  334. 甘油三酯葡萄糖腰重指数:老年肌少症性肥胖患者轻度认知障碍的新生物标志物

    Triglyceride-Glucose-Waist-to-Weight Index: Novel Biomarker for Mild Cognitive Impairment in Older People With Sarcopenic Obesity.

  335. 同时重建球尿道和肛门括约肌复合体:创伤管理中双重修复的病例报告

    Simultaneous reconstruction of bulbar urethra and anal sphincter complex: A case report on dual repair in trauma management.

  336. 心血管-肾脏代谢综合征0-3期患者C-反应蛋白甘油三酯葡萄糖及其改良指标的累积暴露和动态轨迹与心血管疾病的相关性:基于CHARLS的纵向分析

    Association of cumulative exposure and dynamic trajectories of the C-reactive protein-triglyceride-glucose and its modified indices with cardiovascular disease in individuals with cardiovascular-kidney-metabolic syndrome stages 0-3: a longitudinal analysis based on CHARLS.

  337. 脂质纳米粒子介导的IL-33mRNA和STING激动剂的共同递送调节乳腺癌症微环境并增强免疫疗法

    Lipid nanoparticle-mediated co-delivery of IL-33 mRNA and STING agonist modulates the breast cancer microenvironment and potentiates immunotherapy.

  338. 基于生物信息学和机器学习识别与肝硬化和肌肉减少症相关的PTPRR基因

    Identification of PTPRR gene associated with cirrhosis and sarcopenia based on bioinformatics and machine learning.

  339. 头颈癌患者多原发恶性肿瘤的模式:一项为期20年的单机构队列研究

    Patterns of multiple primary malignancies in patients with head and neck cancer: a 20-year single-institution cohort study.

  340. 生态因素和遗传特征与致病性蜱传病毒的生态普遍性有关

    Ecological factors and genetic features are associated with ecological generalism in pathogenic tick-borne viruses.

  341. 白藜芦醇调节sFRP4/Wnt信号通路,并保持缺血性卒中大鼠血脑屏障的完整性

    Resveratrol modulates the sFRP4/Wnt signaling Pathway and preserves blood-brain barrier integrity in rats with ischemic stroke.

  342. Romidepsin抑制NRF2,并通过诱导KRAS突变肿瘤细胞的自噬性细胞死亡来增强阿达格司的疗效

    Romidepsin inhibits NRF2 and enhances the efficacy of adagrasib by inducing autophagic cell death in KRAS-mutant tumor cells.

  343. 社区居住的老年人大脑“脏态”白质与认知能力下降和痴呆症风险的关系

    Cerebral "Dirty-Appearing" White Matter in Relation to Cognitive Decline and Dementia Risk in Community-Dwelling Older Adults.

  344. 定制化角膜交联术治疗圆锥角膜的临床结局与安全性:系统评价与荟萃分析

    Clinical Outcomes and Safety of Customized Corneal Cross-linking for Keratoconus: A Systematic Review and Meta-analysis.

  345. 基于多媒体平台的老年糖尿病患者家庭护理管理

    Multimedia Platform-based Home Care Management for Elderly Patients with Diabetes.

  346. 非典型失神癫痫持续状态患者的遗传景观:一项系统综述

    Genetic landscape of patients with atypical absence status epilepticus: A systematic review.

  347. 超声支气管镜引导下经支气管纵隔冷冻活检的诊断率与组织病理学评估:两种隧道方法的的前瞻性比较

    Diagnostic yield and histopathological assessment of endobronchial ultrasound-guided transbronchial mediastinal cryobiopsy: a prospective comparison of two tunnelling approaches.

  348. 端粒酶逆转录酶通过激活BMP4/Smad1通路介导骨质疏松症的骨形成

    Telomerase reverse transcriptase mediates bone formation for osteoporosis via activating BMP4/Smad1 pathway.

  349. 迷迭香酸减轻颞叶皮层与年龄相关的EEG复杂性损失:复发量化分析

    Rosmarinic acid mitigates age-related loss of EEG complexity in temporal cortex: a recurrence quantification analysis.

  350. PD-L1/CTLA-4检查点抑制剂相关免疫毒性和全身器官损伤的机制驱动因素

    Mechanistic drivers of PD-L1/CTLA-4 checkpoint inhibitor-associated immune toxicity and systemic organ injury.

  351. 卡塔尔大学学生智能手机使用问题与干眼症症状严重程度之间的关系:一项横断面研究

    The relationship between problematic smartphone use and dry eye disease symptom severity among Qatar University students: A cross-sectional study.

  352. 大韩民国釜山丛林斑疹伤寒的流行趋势和区域危险因素:2019-2023年

    Epidemiological trends and regional risk factors for scrub typhus in Busan, Republic of Korea: 2019-2023.

  353. 情绪困扰在毁容性皮肤病中的作用:从大脑皮肤轴的角度来看

    The role of emotional distress in disfiguring skin diseases: A view from brain-skin axis.

  354. 胎盘生长因子和子宫动脉多普勒预测子痫前期、胎儿生长受限和早产

    Placental Growth Factor and Uterine-Artery Doppler for Prediction of Preeclampsia, Fetal Growth Restriction and Early Preterm Birth.

  355. 神经肌肉阻滞对接受腺样扁桃体切除术的高危儿童阿片类药物消耗的影响:一项随机对照试验

    Effect of neuromuscular blockade on opioid consumption in high-risk children undergoing adenotonsillectomy: A randomized-controlled trial.

  356. 面向资源受限物联网设备低速率隐蔽攻击检测的联邦稀疏学习框架

    Federated sparse-learning framework for detecting low-rate stealth attacks in resource-constrained IoT devices.

  357. 经腰骶部神经调控治疗大便失禁的随机假对照试验

    Randomized Sham-Controlled Trial of Translumbosacral Neuromodulation Therapy for Fecal Incontinence.

  358. 人类大脑中依赖经验的快速结构变化:系统综述

    Experience-dependent rapid structural changes in the human brain: A systematic review.

  359. 人类衰老的多模式时钟

    Multimodal clocks of human aging.

  360. Yakuchinone A通过SESN2/AKT1/NRF2通路减轻衰老肝脏的肝脏缺血再灌注损伤

    Yakuchinone A alleviates hepatic ischemia-reperfusion injury in aging livers via the SESN2/AKT1/NRF2 pathway.

  361. 使用新型3D MOF荧光传感器对奶粉中甲硝唑残留进行超灵敏和选择性检测

    Ultrasensitive and selective detection of metronidazole residues in milk powder using a novel 3D MOF fluorescent sensor.

  362. 高温下耐力运动的碳水化合物补充:系统综述和实用建议

    Carbohydrate supplementation for endurance exercise in the heat: a systematic review with practical recommendations.

  363. 在以西班牙裔为主的社区环境中实施的综合心脏代谢基因检测项目

    An integrated cardiometabolic genetic testing program in a predominantly Hispanic population within a community setting.

  364. 从中国龙游县一例严重发热伴血小板减少综合征的临床病例中了解大别病毒的遗传学

    Genetic insights into dabie bandavirus from a clinical case of severe fever with thrombocytopenia syndrome in Longyou County, China.

  365. 咀嚼功能和虚弱:来自NHANES和CHARLS的见解

    Masticatory function and frailty: insights from NHANES and CHARLS.

  366. GOLD科学委员会对慢性阻塞性肺病加重和心血管风险的看法

    A GOLD Science Committee Perspective on Exacerbations and Cardiovascular Risk In COPD.

  367. 利用线粒体动力学相关风险特征预测肺腺癌的预后和肿瘤微环境

    Leveraging mitochondrial dynamics-related risk signatures to predict the prognosis and tumor microenvironment of lung adenocarcinoma.

  368. 一项以社区为基础的运动干预,以减少韩国中风幸存者受伤的功能风险因素:一项试点随机对照试验

    A community-based exercise intervention to reduce functional risk factors for injury among stroke survivors in South Korea: a pilot randomized controlled trial.

  369. MOPHEUS-Lung:atezolizumab+贝伐单抗+立体定向身体放射治疗转移性非小细胞肺癌患者的生物标志物和临床反应

    MORPHEUS-Lung: biomarkers and clinical response to atezolizumab + bevacizumab + stereotactic body radiotherapy in patients with metastatic non-small cell lung cancer.

  370. 利用自然语言处理评估青光眼护理的随访模式

    Leveraging Natural Language Processing to Assess Follow-Up Patterns in Glaucoma Care.

  371. PROS1的长第一内含子调节小鼠和人类组织中的蛋白S表达

    A long first intron of PROS1 modulates protein S expression across tissues in mice and humans.

  372. 单侧颞叶癫痫患者小脑脑网络异常侧化对语言的影响及其机制

    Effect and mechanism of lateralization of cerebellar-cerebral network abnormalities on language in patients with unilateral temporal lobe epilepsy.

  373. 替罗非班静脉注射替尼普酶治疗急性缺血性卒中:即刻随机临床试验

    Intravenous Tirofiban After Tenecteplase in Acute Ischemic Stroke: The INSTANT Randomized Clinical Trial.

  374. 跨越互补参考系的时间的神经表示

    Neural representation of time across complementary reference frames.

  375. 肉桂醛通过靶向USP18抑制[公式:见正文]-肾上腺素能受体泛素化并抑制TAK1/NF-[公式:见正文]B信号通路改善缺血性心力衰竭

    Cinnamaldehyde Ameliorates Ischemic Heart Failure by Targeting USP18 to Inhibit [Formula: see text]-Adrenergic Receptor Ubiquitination and Suppress TAK1/NF-[Formula: see text]B Signaling Pathway.

  376. {“_”:“综合转录组分析结合验证揭示了TMEM140在牙周炎和脑衰老之间的联系。”,“i”:[“体外”]}

    {"_":"Integrated transcriptomic profiling combined with validation reveals the involvement of TMEM140 in the link between periodontitis and brain aging.","i":["in vitro"]}

  377. 膝骨性关节炎的关节内脂肪衍生细胞疗法:随机对照试验的系统综述

    Intra-articular adipose-derived cell therapies for knee osteoarthritis: a systematic review of randomized controlled trials.

  378. SN38 PLGA纳米颗粒在小鼠结肠炎相关癌症模型中提供持续的抗肿瘤功效并改善结肠炎严重程度

    SN38 PLGA nanoparticles provide sustained antitumor efficacy and ameliorate colitis severity in a murine colitis-associated cancer model.

  379. 肾功能衰竭不仅仅是肾脏病学家的问题

    Renal failure isn't just a nephrologist problem.

  380. 关注脂蛋白(a)

    Focus on lipoprotein(a).

  381. 结合化学分析、网络药理学和体外验证的综合方法,揭示脑康II汤抗血管性痴呆的多靶点机制

    An Integrated Approach Combining Chemical Profiling, Network Pharmacology, and In Vitro Validation to Uncover the Multitarget Mechanisms of Naokang II Decoction against Vascular Dementia.

  382. IBD与癌症交界处的Th9细胞:致癌作用中的上下文依赖因子

    Th9 cells at the intersection of IBD and colorectal cancer: a context-dependent factor in carcinogenesis.

  383. 临床儿科护士数字素养现状及影响因素:一项横断面研究

    Current status and influencing factors of digital literacy among clinical pediatric nurses: a cross-sectional study.

  384. 甘油三酯葡萄糖指数和抗Ro52抗体用于原发性干燥病患者心血管疾病的鉴定

    Triglyceride-glucose index and anti-Ro52 antibody for identification of cardiovascular disease in patients with primary Sjögren's disease.

  385. 经皮耳迷走神经刺激对有产前抑郁倾向的剖宫产妇女产后抑郁的预防作用:一项随机对照试验方案

    Preventive effect of transcutaneous auricular vagus nerve stimulation on postpartum depression in cesarean women with antenatal depressive tendency: a randomized controlled trial protocol.

  386. 万古霉素诱导的中国老年患者急性肾损伤:一项多中心回顾性队列研究

    Vancomycin-induced acute kidney injury in older Chinese patients: a multicenter retrospective cohort study.

  387. 症状性遗传性ATTR淀粉样变性伴周围神经病变的神经和皮肤活检以及脂肪抽吸对淀粉样蛋白的敏感性

    Sensitivity of Nerve and Skin Biopsy and Fat Aspirate for Amyloid in Symptomatic Hereditary ATTR Amyloidosis With Peripheral Neuropathy.

  388. GnRH神经元中雌激素受体的表达:回到未来

    Estrogen receptor expression in GnRH neurons: back to the future†.

  389. 中老年人24小时休息活动节律和表观年龄加速

    Twenty-Four-Hour Rest-Activity Rhythms and Epigenetic Age Acceleration in Middle-Aged and Older Adults.

  390. 良性前列腺增生引起的下尿路症状的管理:AUA指南(2026)第一部分:介绍和评估

    Management of Lower Urinary Tract Symptoms Attributed to Benign Prostatic Hyperplasia: AUA Guideline (2026) Part I: Presentation and Evaluation.

  391. 基线甘油三酯胆固醇体重指数和心血管疾病发病风险:来自CHARLS和ELSA队列的证据

    Baseline triglyceride-cholesterol-body weight index and risk of incident cardiovascular disease: evidence from the CHARLS and ELSA cohorts.

  392. 针刺治疗慢性阻塞性肺疾病急性加重的疗效:网络荟萃分析

    Efficacy of acupuncture in managing acute exacerbation of chronic obstructive pulmonary disease: a network meta-analysis.

  393. 严重发热伴血小板减少综合征的环境、气候和社会风险因素以及气候变化的影响

    Environmental, climatic, and social risk factors of severe fever with thrombocytopenia syndrome and the implications of climate change.

  394. 化学抑制细菌免疫系统可复活被抑制的噬菌体

    Chemical suppression of a bacterial immune system revives repressed phages.

  395. 肿瘤来源的外泌体的调节和癌症相关成纤维细胞的重编程用于结直肠癌癌症治疗

    Modulation of tumor-derived exosomes and reprogramming of cancer-associated fibroblasts for colorectal cancer therapy.

  396. 老年关节置换术患者术前睡眠障碍和术后谵妄:一项前瞻性队列研究

    Preoperative sleep disturbance and postoperative delirium in elderly joint replacement patients: a prospective cohort study.

  397. 混合现实自动系统在脑膜瘤切除开颅手术中提高精准度:一项多中心研究

    A MiXed-Reality automatic system for enhanced precision in craniotomy procedure for meningioma resection: A multicentric study.

  398. Daraxonasib在先前治疗的晚期RAS-突变的癌症中的作用

    {"_":"Daraxonrasib in Previously Treated Advanced -Mutated Pancreatic Cancer.","i":["RAS"]}

  399. 磷酸二酯酶抑制剂在男性生殖健康中的治疗应用:叙述性综述

    Therapeutic applications of phosphodiesterase inhibitors in male reproductive health: narrative review.

  400. 心房颤动患者的心肾代谢表型和不良临床结果

    Cardio-Kidney-Metabolic Phenotypes and Adverse Clinical Outcomes in Patients With Atrial Fibrillation.

  401. 时间I型IFN信号协调流感后的保护性和致病性炎症

    Temporal type I IFN signaling orchestrates protective and pathogenic inflammation post-influenza.

  402. 2型糖尿病心力衰竭事件的预测:DM-heart研究的基本原理和设计

    Prediction of incident heart failure in type 2 diabetes mellitus: Rationale and design of the DM-HEART study.

  403. 具有协同位点和级联ROS消除的金属有机复合物工程人工金属酶治疗脑缺血再灌注损伤

    Metal-Organic Complex-Engineered Artificial Metalloenzymes With Synergistic Site and Cascade ROS Elimination to Treat Cerebral Ischemic-Reperfusion Injury.

  404. 间充质干细胞来源外泌体在消化系统恶性肿瘤中的多面性作用:机制与治疗意义

    The multifaceted roles of mesenchymal stem cell-derived exosomes in digestive system malignancies: mechanisms and therapeutic implications.

  405. 机器学习应用于蛋白质组学、代谢组学和多组学生物标志物,用于诊断和风险分层保留射血分数(HFpEF)的心力衰竭:系统综述

    Machine Learning Applied to Proteomic, Metabolomic, and Multi-Omics Biomarkers for the Diagnosis and Risk Stratification of Heart Failure With Preserved Ejection Fraction (HFpEF): A Systematic Review.

  406. 开发临床评分系统,以预测临床诊断的血管性勃起功能障碍患者对低强度冲击波治疗的反应:一项前瞻性、非随机、单臂、干预性研究

    Development of a clinical scoring system to predict response to low-intensity shock wave therapy in clinically diagnosed vasculogenic erectile dysfunction: a prospective, non-randomized, single-arm, interventional study.

  407. 泛素修饰酶作为肠道炎症中的细胞命运调节因子

    Ubiquitin-Modifying Enzymes as Cell-Fate Regulators in Intestinal Inflammation.

  408. UFSP2-C1orf27复合体将新生GPCR定位到用于ER出口管制的ufmylation系统

    The UFSP2-C1orf27 complex positions nascent GPCRs to the ufmylation system for ER export control.

  409. 医院废水中抗生素耐药性风险演变和多菌控制策略的进展

    Advances in the evolution of antibiotic resistance risks in hospital wastewater and multibarrier control strategies.

  410. 对马来西亚西部彭亨丛林斑疹伤寒阳性地区野外采集的恙螨(蜱螨:恙螨科)和小型哺乳动物进行恙虫病东方体(立克次体:立克次体科)的学术调查和检测

    Acarological investigation and detection of Orientia tsutsugamushi (Rickettsiales: Rickettsiaceae) in field-collected chiggers (Acari: Trombiculidae) and small mammals from scrub typhus positive localities in Pahang, West Malaysia.

  411. 晚间右美托咪啶鼻喷雾剂对腹腔镜胆囊切除术患者术后睡眠障碍的影响:一项多中心、前瞻性、随机、双盲、对照试验的方案

    Effect of evening dexmedetomidine nasal spray on postoperative sleep disturbance in patients undergoing laparoscopic cholecystectomy: protocol for a multicentre, prospective, randomised, double-blind, controlled trial.

  412. 一种靶向多功能NS2A蛋白的正黄病毒抑制剂,这是一种以前未鉴定的靶点。

    An orthoflavivirus inhibitor targeting multifunctional NS2A protein, a previously unidentified target.

  413. 妊娠期腹腔镜胆囊切除术:五年单中心经验

    Laparoscopic cholecystectomy during pregnancy: A five-year single-centre experience.

  414. 干细胞因子及其受体c-Kit对癌症引起的骨痛的贡献

    The contribution of stem cell factor and its receptor c-Kit to cancer-induced bone pain.

  415. 通过整合化学同位素标记和基于知识的预测发现新的乳酰基代谢物

    Discovery of Novel Lactoyl-Metabolites by Integrating Chemical Isotope Labeling and Knowledge-Based Prediction.

  416. 将筛查引导的近红外适配传感器集成到便携式平台中,用于定量现场检测N1甲基腺苷

    {"_":"Integration of a screening-guided near-infrared aptasensor into a portable platform for quantitative on-site detection of N-methyladenosine.","sup":["1"]}

  417. 2个月大婴儿重度百日咳合并肺动脉高压的早期静脉-动脉体外膜肺氧合与气道清除技术:病例报告

    Early venoarterial extracorporeal membrane oxygenation with airway clearance techniques in severe pertussis with pulmonary hypertension in a two-month-old infant: a case report.

  418. ENO2驱动肿瘤细胞诱导的M2巨噬细胞极化,促进结直肠癌癌症肝转移

    ENO2 drives tumor cell-induced M2 macrophage polarization to promote colorectal cancer liver metastasis.

  419. 远程缺血预处理联合低强度阻力训练在行动障碍老年人中的可行性和可接受性:一项随机对照的试点试验方案。

    Feasibility and acceptability of remote ischemic conditioning combined with low-intensity resistance training in older adults with mobility impairments: A randomized controlled pilot trial protocol.

  420. 乙型肝炎:综述

    Hepatitis B: A Review.

  421. 慢性心力衰竭患者的充血和肾功能

    Congestion and renal function in patients with chronic heart failure.

  422. 肠鼻轴中的关键信使:肠道微生物代谢产物在变应性鼻炎免疫调节中的机制

    Key messengers in the gut-nose axis: mechanisms of gut microbial metabolites in the immunomodulation of allergic rhinitis.

  423. 全球英语主导的医疗保健人工智能话语:对X上的#AIinHealthcare运动的三年纵向分析

    Global English-language-dominated discourse on artificial intelligence in healthcare: a three-year longitudinal analysis of the #AIinHealthcare movement on X.

  424. 预防卒中相关性肺炎的多学科分层非药物气道清除干预:一项准实验研究

    Multidisciplinary and stratified non-pharmacological airway clearance intervention to prevent stroke-associated pneumonia: a quasi-experimental study.

  425. 经皮耳迷走神经刺激缓解二甲双胍相关胃肠道不良事件并优化血糖控制:一项随机、假对照试点试验方案

    Transcutaneous auricular vagus nerve stimulation to alleviate metformin-associated gastrointestinal adverse events and optimize glycaemic control: a randomized, sham-controlled pilot trial protocol.

  426. 病毒性出血热治疗和疫苗开发的成就和挑战:最新综述。

    Achievements and Challenges in Therapy and Vaccines Development of Viral Hemorrhagic Fevers: An Up-to-Date Review.

  427. 创新的口腔纳米纤维,可同时输送他达拉非和达泊西汀治疗勃起功能障碍和早泄

    Innovative Buccal Nanofibers for Dual Delivery of Tadalafil and Dapoxetine for Erectile Dysfunction and Premature Ejaculation Conditions.

  428. 三叶草提取物(Liboost®)的黄酮类成分和潜在性增强特性的分子基础

    {"_":"Flavonoid Composition and Molecular Basis of the Potential Sexual-Enhancing Properties of a Extract (Liboost).","i":["Turnera diffusa"],"sup":["®"]}

  429. 40岁以下女性子宫内膜息肉与生育力低下:病理生理学、生育结局及临床管理

    Endometrial Polyps and Subfertility in Women Under 40: Pathophysiology, Fertility Outcomes, and Clinical Management.

  430. 评估食管癌和癌症患者生成性人工智能反应的准确性和可读性

    Assessing the Accuracy and Readability of Generative Artificial Intelligence Responses for Esophageal and Gastric Cancer Patients.

  431. 从再生机制到临床实践:泌尿学和性医学中富血小板血浆的现状、争议和未来前景

    From Regenerative Mechanisms to Clinical Practice: Current Status, Controversies, and Future Perspectives of Platelet-Rich Plasma in Urology and Sexual Medicine.

  432. 静脉注射利多卡因对纤维肌痛患者睡眠和生活质量的影响:一项观察性研究

    The Effect of Intravenous Lidocaine Treatment on Sleep and Quality of Life in Fibromyalgia: An Observational Study.

  433. 基于运动的外周动脉疾病心脏康复

    Exercise-Based Cardiac Rehabilitation for Peripheral Artery Disease.

  434. 多组学分析确定ANLN是非小细胞肺癌复发和转移的预后生物标志物

    {"_":"Multi-Omics Analyses Identify as a Prognostic Biomarker for Recurrence and Metastasis in Non-Small Cell Lung Cancer.","i":["ANLN"]}

  435. 大豆和野生大豆叶片对青桃白蛉饲养性能的比较影响

    {"_":"Comparative Effects of and Leaves on Rearing Performance.","i":["Glycine max","Glycine soja","Clanis bilineata tsingtauica"]}

  436. 肠道微生物群和自闭症谱系障碍:当前研究和治疗见解

    The Gut Microbiota and Autism Spectrum Disorder: Current Research and Therapeutic Insights.

  437. 内皮糖萼在慢性肾脏病和高血压病理生理学中的作用:从分子机制到临床生物标志物

    The Role of Endothelial Glycocalyx in the Pathophysiology of Chronic Kidney Disease and Hypertension: From Molecular Mechanisms to Clinical Biomarkers.

  438. 有毒重金属暴露与偏头痛之间的关系以及抗炎饮食的调节作用:一项基于人群的横断面研究

    The relationship between toxic heavy metal exposure and migraine and the modulatory role of an anti-inflammatory diet: A population-based cross-sectional study.

  439. 美国成年人C-反应蛋白甘油三酯葡萄糖指数与骨关节炎的相关性:来自NHANES的证据(2017-2020)

    Association between C-reactive protein-triglyceride glucose index and osteoarthritis in US adults: Evidence from NHANES (2017-2020).

  440. 中国中老年人甘油三酯葡萄糖虚弱指数与心脏代谢多发病率的关系:一项全国性前瞻性队列研究

    The association between triglyceride glucose-frailty index and cardiometabolic multimorbidity among Chinese middle-aged and older adults: a national prospective cohort study.

  441. 薄膜扩散梯度技术在地表水降雨事件中药物原位监测的研究与应用

    Investigation and application of diffusive gradients in thin films for in situ monitoring of pharmaceuticals in surface water during rainfall events.

  442. 登革热蛋白酶介导巨噬细胞的活化和极化。

    Dengue protease-mediated activation and polarization of macrophages.

  443. 新疆帕米尔高原高海拔肺动脉高压的蛋白质组学研究

    Proteomic study of high-altitude pulmonary hypertension in the Xinjiang Pamir highlanders.

  444. 护生数字素养与临床决策能力的关系:一项横断面研究

    The relationship between digital literacy and clinical decision-making skills among student nurses: a cross sectional study.

  445. 谁会失败?识别非骨水泥全膝关节置换术后无菌性松动的风险

    Who Fails? Identifying Risks for Aseptic Loosening After Cementless Total Knee Arthroplasty.

  446. IGF2BP3通过ETV4介导的GCH1调节抑制铁蛋白脱失,促进癌症进展。

    IGF2BP3 promotes gastric cancer progression by inhibiting ferroptosis through ETV4-mediated regulation of GCH1.

  447. 协调优化大肠杆菌中3'-磷酸腺苷-5'-磷酸硫酸盐(PAPS)的供应和磺基转移酶的表达,以生产高硫酸化程度的硫酸软骨素A。

    Coordinated optimization of 3'-phosphoadenosine-5'-phosphosulfate (PAPS) supply and sulfotransferase expression in Escherichia coli for production of chondroitin sulfate A with high sulfation degree.

  448. 衰老相关的CCL8+衰老巨噬细胞招募CCR1+中性粒细胞以促进NETs形成并损害脑膜淋巴引流

    {"_":"Aging-Associated CCL8 Senescent Macrophages Recruit CCR1 Neutrophils to Promote NETs Formation and Impair Meningeal Lymphatic Drainage.","sup":["+","+"]}

  449. 根据糖尿病肾病分期,2型糖尿病患者的维生素D和心血管自主神经病变

    Vitamin D and cardiovascular autonomic neuropathy in type 2 diabetes mellitus according to diabetic kidney disease stage.

  450. 超重或肥胖个体的母体脂溶性维生素轨迹和婴儿出生体重

    Maternal fat-soluble vitamin trajectories and infant birth weight in individuals with overweight or obesity.

  451. 心血管疾病中的免疫炎症代谢相互作用:从基本机制到临床翻译的综述

    Immuno-inflammatory-metabolic interactions in cardiovascular diseases: a review from basic mechanisms to clinical translation.

  452. 溃疡性结肠炎中的结直肠癌癌症:揭示机制并推进监测和化学预防

    Colorectal cancer in ulcerative colitis: unraveling mechanisms and advancing surveillance and chemoprevention.

  453. 使用GHRH受体类似物的间充质干细胞治疗通过调节AQP4和线粒体ER串扰来解决卒中后血管源性水肿

    Mesenchymal Stem cell therapy with GHRH receptor analog resolves post-stroke vasogenic edema via modulating AQP4 and mitochondria-ER crosstalk.

  454. 肌肉减少症与颈动脉斑块之间的关联:炎症生物标志物的中介分析

    The association between sarcopenia and carotid artery plaque: a mediation analysis of inflammatory biomarkers.

  455. TyHGB与2型糖尿病患者高尿酸血症和痛风的关系

    Association between TyHGB and hyperuricemia and gout in patients with type-2 diabetes mellitus.

  456. 中药治疗变应性鼻炎的多靶点机制

    Multi-target mechanisms of Chinese herbal medicine in the treatment of allergic rhinitis.

  457. 与多器官衰竭和异常皮肤表现相关的致命性严重发热伴血小板减少综合征:血红性鼻炎(褐狗蜱)传播的证据

    Fatal severe fever with thrombocytopenia syndrome associated with multiorgan failure and unusual cutaneous manifestations: evidence of Rhipicephalus sanguineus (Brown Dog Tick) transmission.

  458. 检查健康信息查询中的用户AI交互模式

    Examining user-AI interaction patterns in health-Information queries.

  459. 佐剂给药益生菌对接受选择性血清素再摄取抑制剂治疗的抑郁症男性性功能的影响:一项双盲随机对照试验

    Adjuvant administration probiotic effects on sexual function in depressant men undergoing selective serotonin reuptake inhibitor treatment: a double-blinded randomized controlled trial.

  460. 探讨脓毒症相关心脏功能障碍的机制和管理

    Exploring the mechanisms and management of sepsis-related cardiac dysfunction.

  461. 铁下垂驱动的衰老环是骨关节炎进展的中枢放大器

    Ferroptosis-Driven Senescence Loop as a Central Amplifier of Osteoarthritis Progression.

  462. {"_":"腺苷A受体和A受体在睡眠障碍中的作用:机制与治疗意义。","sub":["1","2A"]}

    {"_":"Adenosine A and A Receptors in Sleep Disorders: Mechanisms and Therapeutic Implications.","sub":["1","2A"]}

  463. 原位自组装刺激反应性导电水凝胶通过PPARα/NFκB信号调节心肌梗死炎症稳态,增强hiPSC-CMs的治疗效果

    In situ self-assembled stimulus-responsive and conductive hydrogel modulate myocardial infarction inflammatory homeostasis via PPARα/NFκB signaling and enhance the therapeutic efficacy of hiPSC-CMs.

  464. 非酒精性脂肪性肝病患者自我管理教育的证据总结

    Evidence Summary for Self-Management Education in Patients with Non-Alcoholic Fatty Liver Disease.

  465. 伴有肾损伤的神经元核内包涵体疾病的免疫学特征:多中心队列的探索性分析

    Immunological characterization of neuronal intranuclear inclusion disease with kidney injury: an exploratory analysis in a multi-center cohort.

  466. 星形胶质细胞中的PTP1B驱动病原体诱导的神经变性

    PTP1B in astrocytes drives pathogen-induced neurodegeneration.

  467. 中国一个高发区严重发热伴血小板减少综合征的传播性不断上升

    Escalating transmissibility of severe fever with thrombocytopenia syndrome in a high-endemic region of China.

  468. 针对自闭症谱系障碍儿童左初级运动皮层的加速连续θ脉冲刺激:多中心随机假对照试验

    Accelerated continuous theta burst stimulation targeting left primary motor cortex for children with autism spectrum disorder: multicentre randomised sham controlled trial.

  469. 压力损伤严重程度和轨迹:澳大利亚卫生区的一项为期5年的队列研究

    Pressure injury severity and trajectory: A 5-year cohort study in an Australian health district.

  470. 关注差距:儿童期和青春期边缘智力功能的系统综述

    Mind the Gap: A Systematic Review of Borderline Intellectual Functioning in Childhood and Adolescence.

  471. 针对脂质-纤维化信号串扰进行抗纤维化治疗

    Targeting lipid-fibrotic signaling crosstalk for antifibrotic therapy.

  472. 癌症头颈部脑转移201例分析

    Brain metastasis in head and neck cancer: an analysis of 201 cases.

  473. 多囊卵巢综合征胰岛素抵抗和糖代谢改变的分子机制:范围综述

    Molecular mechanisms of insulin resistance and altered carbohydrate metabolism in PCOS: a scoping review.

  474. 仿生核壳微胶囊通过提高非孢子细菌的稳定性和存活率来增强植物的耐盐性

    Bio-inspired core-shell microcapsules enhance plant salinity tolerance by improving stability and survival of non-spore bacteria.

  475. 生成性人工智能与网络搜索在患者教育中的应用:OSA信息质量的比较评估

    Generative AI vs web search for patient education: a comparative evaluation of OSA information quality.

  476. 肠道微生物群调节在预防和治疗肝硬化患者少肌症中的作用:一项叙述性综述

    Role of gut microbiota modulation in preventing and treating sarcopenia in patients with liver cirrhosis: A narrative review.

  477. 父系昼夜节律紊乱通过精子microRNAs影响后代认知

    Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs.

  478. 谁在写疫情?国家权力、个体主体性和中国应对新冠肺炎的历史现状

    Who writes the pandemic? State power, individual subjectivity, and the history of the present in China's COVID-19 response.

  479. 追踪和评估基于社区的TeSting的前瞻性呼吸结果(项目保护):一项基于社区的、对美国成年人急性呼吸道感染的前瞻性研究——队列分析

    Prospective Respiratory Outcomes from Tracking and Evaluating Community-based TeSting (Project PROTECTS): a community-based, prospective study of acute respiratory infections among adults across the USA - cohort profile.

  480. 具有机器人反馈的混合SSVEP运动图像BCI用于中风患者上肢运动康复的可行性

    Feasibility of a hybrid SSVEP-motor imagery BCI with robotic feedback for upper limb motor rehabilitation in stroke patients.

  481. 多模态大语言模型、单峰ChatGPT 5.0和人类临床专家在伤口护理认证考试中的力量:横断面比较研究

    The Power of Multimodality in Multimodal Large Language Models, Unimodal ChatGPT 5.0, and Human Clinical Experts on a Wound Care Certification Examination: Cross-Sectional Comparative Study.

  482. 腺苷A2A受体控制反复束缚应激大鼠中水通道蛋白-4的错误定位

    {"_":"Adenosine A Receptors Control the Mis-Localization of Aquaporin-4 in Rats Subject to Repeated Restraint Stress.","sub":["2A"]}

  483. 河北省蜱病毒组多样性的转录组分析

    Metatranscriptomic Analysis of Tick Virome Diversity in Hebei Province, China.

  484. 希腊护士在临床护理实践中采用人工智能的数字技能和准备情况

    Digital Skills and Readiness of Greek Nurses for Artificial Intelligence Adoption in Clinical Nursing Practice.

  485. Zingerone通过降低颞叶癫痫大鼠模型中海马神经元的内在兴奋性来缓解急性癫痫发作

    Zingerone alleviates acute seizures by reducing intrinsic hippocampal neuronal excitability in a rat model of temporal lobe epilepsy.

  486. 6周盆底肌训练对健康年轻男性神经肌肉活动的影响:一项初步研究

    Effects of a 6-week pelvic floor muscle training on neuromuscular activity in healthy young men: a pilot study.

  487. 人造和天然非营养性甜味剂会在几代人之间引发不同的肠道和遗传反应

    Artificial and natural non-nutritive sweeteners drive divergent gut and genetic responses across generations.

  488. 脂肪是驱动因素,而不是旁观者:肥胖相关勃起功能障碍的现代综合

    Adipose as a Driver, Not a Bystander: A Modern Synthesis of Obesity-Related Erectile Dysfunction.

  489. 糖尿病足溃疡患者念珠菌耐药性:系统评价和荟萃分析

    Candida Drug Resistance in Patients With Diabetic Foot Ulcers: A Systematic Review and Meta-Analysis.

  490. 什么是翼下颌缝?筋膜的汇合,而不是离散的结构

    What Is the Pterygomandibular Raphe? A Confluence of Fasciae Rather Than a Discrete Structure.

  491. 代谢状态改变了C-反应蛋白甘油三酯葡萄糖指数腰高比对主要不良心脑血管事件的预测值:中国健康与退休纵向研究(CHARLS)的一项前瞻性队列研究

    Metabolic status modifies the predictive value of the C-reactive protein-triglyceride-glucose Index-waist-to-height ratio for major adverse cardiovascular and cerebrovascular events: a prospective cohort study from the China Health and Retirement Longitudinal Study (CHARLS).

  492. 想知道:微生物组、过敏性疾病和抗菌化学物质

    Itching to know: the Microbiome, Allergic Disease, and Antimicrobial Chemicals.

  493. 血浆蛋白质组和自闭症谱系障碍:全蛋白质组孟德尔随机化与临床分析

    Plasma proteome and autism spectrum disorder: Integrative proteome-wide Mendelian randomization with clinical profiling.

  494. 巨噬细胞共表达特征能够对胶质母细胞瘤进行稳健的预后预测

    A macrophage co-expression signature enables robust prognostic prediction in glioblastoma.

  495. 基于老年评估的弥漫性大B细胞淋巴瘤老年患者治疗:二十年临床经验的结果

    Geriatric assessment-based therapy for older patients with diffuse large B-cell lymphoma: results of a two-decade clinical experience.

  496. 糖尿病足感染的病原体特征和炎症生物标志物:与疾病严重程度的相关性

    Pathogen profile and inflammatory biomarkers in diabetic foot infections: correlation with disease severity.

  497. 限制计算机断层扫描期间造影剂外渗的风险因素和策略:范围综述

    Risk factors and strategies to limit contrast media extravasation during computed tomography: A scoping review.

  498. 通过局部加速碳化模拟贵金属RWGS活性的应变Ni-WC纳米岛

    Strained Ni-WC nano-islands by localized accelerated carbonization emulate noble-metal RWGS activity.

  499. 维生素D3与三联疗法协同作用,通过c-Raf/MEK/ERK途径根除小鼠幽门螺杆菌感染

    {"_":"Vitamin D in synergy with triple therapy to eradicate Helicobacter pylori infection in mice via the c-Raf/MEK/ERK pathway.","sub":["3"]}

  500. 帕金森病和痴呆症患者的团体认知刺激疗法

    Group Cognitive Stimulation Therapy for people living with Parkinson's disease and dementia.