新出现的重要蜱传病原体的研究进展
Research progress on emerging and important Tick-Borne pathogens.
摘要(中文译文)
蜱是重要的媒介节肢动物，可携带并传播多种病原微生物，对全球公共卫生构成严重威胁。本研究综述了莱姆病相关病原体、发热伴血小板减少综合征病毒（SFTSV）、蜱传脑炎病毒（TBEV）、阿龙山病毒（ALSV）等主要及新发蜱传病原体的研究进展，重点关注其基因组多样性、致病性、传播与免疫逃逸及混合感染。此外，总结了新型检测技术[成簇规律间隔短回文重复序列（CRISPR）、宏基因组二代测序（mNGS）、微流控技术]在蜱传病原体中的应用。研究强调了当前研究的局限性，包括疫苗研发滞后和监测体系不完善。最后，对未来研究方向进行了展望，为蜱传疾病的防控提供理论参考。
Abstract
Ticks are important vector arthropods, which can carry and transmit a variety of pathogenic microorganisms, and pose a serious threat to global public health. This study reviews the research progress of the main and emerging tick-borne pathogens, such as Lyme disease related , Thrombocytopenia Syndrome Virus (SFTSV), Tick-borne Encephalitis Virus (TBEV), Alongshan virus (ALSV), etc., focuses on their genomic diversity, pathogenicity, transmission and immune escape, co- infection. In addition, the application of new detection technology [Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR), metagenomic next-generation sequencing (mNGS), microfluidics] in Tick-Borne pathogens is summarized.It highlights current research limitations, including delayed vaccine development and inadequate surveillance systems. Finally, future research directions are prospected, providing theoretical references for the prevention and control of tick-borne diseases.
如何引用
AMA
Gang Duan, Linghan Kong, Sicheng Duan, Shujun Nie, Wanjiang Gu. Research progress on emerging and important Tick-Borne pathogens.. Frontiers in microbiology. 2026; doi:10.3389/fmicb.2026.1866307.
APA
Gang Duan, Linghan Kong, Sicheng Duan, Shujun Nie, Wanjiang Gu (2026). Research progress on emerging and important Tick-Borne pathogens.. Frontiers in microbiology. https://doi.org/10.3389/fmicb.2026.1866307
GB/T 7714
Gang Duan, Linghan Kong, Sicheng Duan, Shujun Nie, Wanjiang Gu. Research progress on emerging and important Tick-Borne pathogens.[J]. Frontiers in microbiology, 2026 doi:10.3389/fmicb.2026.1866307.
在 PubMed增强版 阅读全文
翻译全文 · AI 文献问答 · PDF 原文下载 · 引用导出