针对肠道微生物群的精准营养用于体重管理：机制和应用
Precision nutrition targeting the gut microbiota for weight management: mechanisms and applications.
摘要(中文译文)
肠道菌群是一个高度个体化的微生物群落，其在体重调节和代谢健康中的作用日益受到重视。本叙述性综述探讨了肠道菌群与体重管理之间的双向关联，重点关注涉及能量代谢、免疫调节、炎症反应和食欲控制的机制。我们还探讨了肠道菌群与宿主遗传/表观遗传因素在肥胖发生中的相互作用。本综述讨论了精准营养干预如何调节肠道菌群组成，以支持个性化体重管理策略。此外，我们探讨了人工智能与多组学技术的整合，概述了当前的挑战和未来方向。本综述旨在为将靶向肠道菌群的精准营养转化为临床和研究环境中的有效体重管理提供理论基础。
Abstract
The gut microbiota, a highly individualized microbial community, is increasingly recognized for its role in weight regulation and metabolic health. This narrative review examines the bidirectional associations between gut microbiota and weight management, focusing on mechanisms involving energy metabolism, immune modulation, inflammatory responses, and appetite control. We also explore the interplay between gut microbiota and host genetic/epigenetic factors in obesity development. The review discusses how precision nutrition interventions may modulate gut microbiota composition to support personalized weight management strategies. Furthermore, we address the integration of artificial intelligence and multi-omics technologies, outlining current challenges and future directions. This review aims to provide a theoretical foundation for translating gut microbiota-targeted precision nutrition into clinical and research settings for effective weight management.
如何引用
AMA
Liyuan Jin, Yuan Zhu, Yaozhe Ying, Pengcheng Yan, Huanzhi Jin, Zheyan Chen. Precision nutrition targeting the gut microbiota for weight management: mechanisms and applications.. Frontiers in microbiology. 2026; doi:10.3389/fmicb.2026.1806152.
APA
Liyuan Jin, Yuan Zhu, Yaozhe Ying, Pengcheng Yan, Huanzhi Jin, Zheyan Chen (2026). Precision nutrition targeting the gut microbiota for weight management: mechanisms and applications.. Frontiers in microbiology. https://doi.org/10.3389/fmicb.2026.1806152
GB/T 7714
Liyuan Jin, Yuan Zhu, Yaozhe Ying, Pengcheng Yan, Huanzhi Jin, Zheyan Chen. Precision nutrition targeting the gut microbiota for weight management: mechanisms and applications.[J]. Frontiers in microbiology, 2026 doi:10.3389/fmicb.2026.1806152.
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