国际细胞学学院横滨系统与改良Masood评分指数在可触及乳腺病变细针穿刺细胞学中的比较分析
Comparative Analysis of the International Academy of Cytology Yokohama System and the Modified Masood Scoring Index in Fine Needle Aspiration Cytology of Palpable Breast Lesions.
摘要(中文译文)
乳腺癌在印度的发病率已超过宫颈癌，凸显了筛查和早期发现的重要性。三联检测，包括临床检查、乳腺X线摄影和细针穿刺细胞学检查（FNAC），对于评估可疑乳腺病变至关重要。FNAC是一种简便且微创的方法，能有效诊断良性和恶性病变，有助于治疗，尽管形态学特征重叠有时会导致诊断错误。本回顾性研究纳入2023年2月至2024年7月期间转诊至维迪沙阿塔尔·比哈里·瓦杰帕伊政府医学院病理科行FNAC的患者。细胞学玻片被调取并由两名受过培训的细胞病理学家在单盲条件下审阅，并应用了两种常用的细胞学分级系统，即国际细胞学学会（IAC）横滨分类和改良Masood评分指数（MMSI）。对可获得的乳腺病变组织病理学切片进行审阅，并与细胞学诊断进行相关性分析。共纳入约174例（在总计535例细针穿刺中）乳腺病变病例，这些病例均进行了细胞组织病理学检查。它们根据横滨系统和MMSI系统进行分类。以组织病理学为标准进行统计分析。IAC横滨系统在诊断准确性、敏感性和临床实用性方面优于MMSI。横滨系统基于恶性肿瘤风险（ROM）的五级结构提供了更清晰的管理路径并减少了模糊性，使其成为常规乳腺细胞病理学首选的通用报告系统。与MMSI相比，横滨系统提供了更优的诊断准确性、标准化的风险分层和实用的临床沟通。其全球验证的、基于ROM的框架使其成为首选且更可靠的报告标准。
Abstract
Breast cancer has surpassed cervical cancer in India, underscoring the importance of screening and early detection. Triple testing, including clinical examination, mammography, and fine needle aspiration cytology (FNAC), is crucial for assessing suspicious breast lesions. FNAC, a simple and minimally invasive method, effectively diagnoses benign and malignant lesions, aiding treatment, though overlapping morphological features can sometimes cause diagnostic errors. This retrospective study involves patients referred for FNAC to the Department of Pathology at Atal Bihari Vajpayee Government Medical College, Vidisha, from February 2023 to July 2024. Cytology slides were retrieved and reviewed by two trained cytopathologists on a single-blind basis, and two commonly used cytological grading systems, i.e., the International Academy of Cytology (IAC) Yokohama Classification and the Modified Masood Scoring Index (MMSI), were applied. Histopathology sections of available breast lesions were reviewed and correlated with cytological diagnoses. Around 174 (out of a total of 535 fine needle aspirations done) cases of breast lesions were taken into account, for which cytohistopathological examinations were done. They were categorized according to the Yokohama and MMSI systems. Statistical analysis was done using histopathology as the standard. The IAC Yokohama system demonstrated superior diagnostic accuracy, sensitivity, and clinical utility compared to the MMSI. The Yokohama system's risk of malignancy (ROM)-based, five-tiered structure provides clearer management pathways and reduced ambiguity, establishing it as the preferred universal reporting system for routine breast cytopathology. The Yokohama system provides superior diagnostic accuracy, standardized risk stratification, and practical clinical communication compared to the MMSI. Its globally validated, ROM-based framework makes it the preferred, more reliable reporting standard.
如何引用
AMA
Utkarsh Tripathi, Pragati Awasthi, Tina Rai. Comparative Analysis of the International Academy of Cytology Yokohama System and the Modified Masood Scoring Index in Fine Needle Aspiration Cytology of Palpable Breast Lesions.. Cureus. 2026; doi:10.7759/cureus.110506.
APA
Utkarsh Tripathi, Pragati Awasthi, Tina Rai (2026). Comparative Analysis of the International Academy of Cytology Yokohama System and the Modified Masood Scoring Index in Fine Needle Aspiration Cytology of Palpable Breast Lesions.. Cureus. https://doi.org/10.7759/cureus.110506
GB/T 7714
Utkarsh Tripathi, Pragati Awasthi, Tina Rai. Comparative Analysis of the International Academy of Cytology Yokohama System and the Modified Masood Scoring Index in Fine Needle Aspiration Cytology of Palpable Breast Lesions.[J]. Cureus, 2026 doi:10.7759/cureus.110506.
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