以小肠梗阻为首发表现的多灶性腹膜黏液癌:一例病例报告
Multifocal Peritoneal Mucinous Carcinoma Presenting as Small Bowel Obstruction: A Case Report.
Multifocal Peritoneal Mucinous Carcinoma Presenting as Small Bowel Obstruction: A Case Report.
累及小肠的黏液癌是肠梗阻的罕见病因,也是一种诊断上具有挑战性的疾病实体。当多灶性黏液沉积累及小肠和腹壁时,明确诊断并确定原发部位需要综合的临床病理学方法。我们报告一例42岁女性,表现为急性小肠梗阻。剖腹探查发现累及回肠和盲肠区域的多个病灶。主要梗阻性病灶位于回肠中段,伴有近端肠管扩张和远端肠管萎陷。另外在距第一个病灶约一米处及回盲瓣附近发现非梗阻性病灶,同时可见一盲肠病灶粘连于右侧输卵管。组织病理学检查显示多灶性黏液癌,伴有大量细胞外黏液池,其中含有恶性上皮细胞浸润肠壁及纤维脂肪组织。本病例突出了以肠梗阻为首发表现的多灶性黏液癌所构成的诊断挑战。认识这一罕见表现对于手术决策和术后肿瘤学评估具有重要意义。
Mucinous carcinoma involving the small bowel is a rare cause of intestinal obstruction and a diagnostically challenging entity. When multifocal mucinous deposits involve the small bowel and abdominal wall, establishing the diagnosis and identifying the site of origin requires an integrated clinicopathological approach. We present a case of a 42-year-old woman who presented with acute small bowel obstruction. Laparotomy revealed multiple lesions involving the ileum and cecal region. The primary obstructing lesion was located in the mid-ileum with proximal bowel dilatation and distal collapse. Additional non-obstructing lesions were identified approximately one meter distal to the first lesion and near the ileocecal valve, along with a cecal lesion adherent to the right fallopian tube. Histopathological examination demonstrated multifocal mucinous carcinoma with abundant extracellular mucin pools containing malignant epithelial cells infiltrating the intestinal wall and fibroadipose tissue. This case highlights the diagnostic challenge posed by multifocal mucinous carcinoma presenting as bowel obstruction. Awareness of this rare presentation is important for surgical decision-making and postoperative oncologic evaluation.
Haytham Mohammed Alzinati, Ahmed Zaki, Abdulmalek Ayman Arbach, Ahmed Fathi Mohamed Alsehily, Ahmed Elsayed Ibrahim Mattar, Ammar Mohamed Saleih Abdullah Basheir. Multifocal Peritoneal Mucinous Carcinoma Presenting as Small Bowel Obstruction: A Case Report.. Cureus. 2026; doi:10.7759/cureus.110258.
Haytham Mohammed Alzinati, Ahmed Zaki, Abdulmalek Ayman Arbach, Ahmed Fathi Mohamed Alsehily, Ahmed Elsayed Ibrahim Mattar, Ammar Mohamed Saleih Abdullah Basheir (2026). Multifocal Peritoneal Mucinous Carcinoma Presenting as Small Bowel Obstruction: A Case Report.. Cureus. https://doi.org/10.7759/cureus.110258
Haytham Mohammed Alzinati, Ahmed Zaki, Abdulmalek Ayman Arbach, Ahmed Fathi Mohamed Alsehily, Ahmed Elsayed Ibrahim Mattar, Ammar Mohamed Saleih Abdullah Basheir. Multifocal Peritoneal Mucinous Carcinoma Presenting as Small Bowel Obstruction: A Case Report.[J]. Cureus, 2026 doi:10.7759/cureus.110258.
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