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4001. 用于小胶质细胞选择性细胞松弛素D递送以调节急性脑损伤后神经炎症的多功能治疗诊断纳米载体平台

      Multifunctional theranostic nanocarrier platform for microglia-selective cytochalasin D delivery to modulate neuroinflammation after acute brain injuries.

4002. 富氧中空MOF作为纳米气泡，通过微针介导的声动力疗法增强对增生性瘢痕的治疗

      Oxygen-enriching hollow MOF as nanobubbles to enhance treatment of hypertrophic scar via microneedle-mediated sonodynamic therapy.

4003. 日本结肠镜检查肠道准备现状：基于网络的内镜医师调查（PRESS调查）

      Current Status of Bowel Preparation for Colonoscopy in Japan: A Web-Based Survey of Endoscopists (PRESS Survey).

4004. 炎症性肠病粪便脂质组的快速分析：一种用于探索性疾病分子特征描述和治疗监测的新方法

      Rapid fecal lipidome profiling in inflammatory bowel disease: A novel approach for exploratory disease molecular characterization and therapeutic monitoring.

4005. 逍遥散通过肠道菌群-脑轴发挥抗抑郁作用：一项fMRI与多组学整合研究

      Xiaoyao San exerts antidepressant effects via the gut microbiota-brain axis: An integrative fMRI and multiomics study.

4006. 一种整合前药纳米颗粒的低交联水凝胶调节神经炎症和ECM沉积，以增强脊髓再生

      A low-crosslinking hydrogel integrating prodrug nanoparticles modulates neuroinflammation and ECM deposition for enhanced spinal cord regeneration.

4007. 纳米病原体搭便车激活中性粒细胞以消除动脉粥样硬化斑块

      Nano-pathogenoids hitchhike activated neutrophils for eliminating of atherosclerosis plaques.

4008. 半胺化水凝胶-锰纳米颗粒杂化物通过微环境调节促进穿透性口腔皮肤瘘管的愈合

      Hemiaminal hydrogel-manganese nanoparticle hybrids boost healing of penetrating orocutaneous fistulas through microenvironmental regulation.

4009. 褪黑素调节的mRNA负载脂质纳米粒增强NRF2介导的间充质干细胞治疗肺纤维化

      Melatonin-tuned mRNA-loaded lipid nanoparticles enhance NRF2-mediated mesenchymal stem cell therapy for pulmonary fibrosis.

4010. 用于可穿戴应变传感器的超硬双网导电水凝胶，具有紫外线阻断、抗菌和抗冻性能

      Ultra-tough dual-network conductive hydrogel with UV-blocking, antibacterial properties and freeze resistance for wearable strain sensor.

4011. 用于膀胱癌症精确光免疫疗法的粘膜穿透NIR-II纳米药物

      Mucosa-penetrating NIR-II nanomedicine for precision photoimmunotherapy of bladder cancer.

4012. 一种基于辅酶的自稳定Janus贴片，用于无缝合糖尿病肌腱愈合的时空调节

      A coenzyme-based self-stabilized Janus adhesive patch for spatiotemporal regulation of sutureless diabetic tendon healing.

4013. 用于胶质母细胞瘤靶向siRNA递送穿过血脑屏障的聚磷酰胆碱修饰脂质体

      Polyphosphorylcholine-modified liposomes for glioblastoma-targeted siRNA delivery across the blood-brain barrier.

4014. 超声波诱导硝酸异山梨酯纳米颗粒释放一氧化氮，用于牙周炎的按需治疗

      Ultrasound-induced nitric oxide release from isosorbide dinitrate nanoparticles for on-demand therapy of periodontitis.

4015. 一种包裹牙囊干细胞衍生的小细胞外囊泡的免疫调节水凝胶可促进中性粒细胞清除和牙周骨再生

      An immunomodulatory hydrogel encapsulating dental follicle stem cell-derived small extracellular vesicles promotes neutrophil clearance and periodontal bone regeneration.

4016. 级联响应型仿生纳米颗粒重塑肿瘤代谢并增强铁死亡以实现侵袭性乳腺癌的协同治疗

      Cascade-responsive biomimetic nanoparticles remodel tumor metabolism and potentiate ferroptosis for synergistic therapy of aggressive breast cancer.

4017. 通过界面工程N-C/g-C3N4光电协同提高锌空气电池性能

      {"_":"Boosting zinc-air battery performance through interface-engineered N-C/g-CN photoelectric synergy.","sub":["3","4"]}

4018. 内源性荧光团的多波长光漂白动力学用于无标记组织表征，并具有利用机器学习估计肿瘤边界的潜力

      Multi-wavelength photobleaching kinetics of endogenous fluorophores for label-free tissue characterization with potential for tumor margin estimation using machine learning.

4019. 利用ATR-FT-IR光谱结合机器学习对基底细胞癌进行大分子表征

      Macromolecular characterization of basal cell carcinoma using ATR-FT-IR spectroscopy combined with machine learning.

4020. “玛丽认为约翰认为……”5至7岁儿童二阶心理状态归因的发展变化与个体稳定性

      "Mary thinks that John thinks that…" Developmental change and individual stability in attributing second-order mental states in 5 to 7-year-olds.

4021. 合作未能促进分享行为，但合作游戏和平行游戏均能增进4至6岁幼儿的友谊

      Collaboration fails to promote sharing behavior but both collaborative and parallel play boost friendship in young children aged 4 to 6.

4022. 身体内部、表面与外部：儿童和青年内感受、身体及导航表征的发展与组织

      Inside, on, and beyond the body: development and organization of interoceptive, bodily, and navigational representations in children and young adults.

4023. 设计功能性血管系统，重建交感-副交感神经回路，以恢复脊髓损伤后的膀胱功能

      Engineering functional vasculatures to reconstruct sympathetic-parasympathetic circuits for bladder function after spinal cord injury.

4024. Y-RBCEVs通过成骨作用和VCAN介导的CD44/PI3K/AKT依赖性巨噬细胞极化加速骨折修复

      Y-RBCEVs accelerate fracture repair through osteogenesis and VCAN-mediated CD44/PI3K/AKT-dependent macrophage polarization.

4025. 双模抗氧化剂和表观遗传协同作用减弱了骨关节炎的自我延续衰老周期

      Dual-modal antioxidant and epigenetic synergy attenuates the self-perpetuating senescence cycle in osteoarthritis.

4026. 儿童的身份融合：动态身份融合指数的验证

      Identity fusion in children: A validation of the Dynamic Identity Fusion Index.

4027. 学龄前儿童的新兴数字书写：跨任务情境下与新兴字母书写及视觉-运动整合的关联

      Emergent number writing in preschoolers: Association with emergent letter writing and visual-motor integration across task contexts.

4028. 纳米乙醇铜通过协同铜吸附和代谢氧化应激实现免疫增强的肝癌放射免疫治疗

      Nanoscale copper ethoxide enables immunologically enhanced hepatoma radio-immunotherapy via synergistic cuproptosis and metabolic oxidative stress.

4029. 水凝胶递送脱矿质骨基质，增强ROS引发的生物矿化和Trb3激活，以增强骨再生

      Hydrogel delivery of demineralized bone matrix augmented with ROS-triggered biomineralization and Trb3 activation for enhanced bone regeneration.

4030. 西地尼布与人血清白蛋白相互作用机制的生物物理学见解：体外和计算机模拟视角

      Biophysical insights into interaction mechanism of cediranib with human serum albumin: In-vitro and in-silico perspectives.

4031. 一种基于特征解耦和注意力机制的小样本近红外光谱分类方法：在黄芪中的应用

      A feature decoupling and attention-based method for small-sample NIR spectral classification: application to Astragalus membranaceus.

4032. 人工智能催化抗菌肽设计

      Artificial intelligence catalyzes antimicrobial peptide design.

4033. 一种新型Zn（II）探针，用于HeLa细胞中丙二酸/焦磷酸/草酸的双模识别和可编程生物成像

      A novel Zn(II) probe for dual-mode discernment of malonate/pyrophosphate/oxalate and programmable bioimaging in HeLa cells.

4034. Stigmasterol通过靶向IGF-1/PI3K/Akt/mTOR信号通路和调节Kisspeptin/GnRH轴来缓解中枢性早熟

      Stigmasterol alleviates central precocious puberty by targeting the IGF-1/PI3K/Akt/mTOR signaling pathway and modulating the Kisspeptin/GnRH axis.

4035. 一种携带衣康酸二甲酯的硼酸酯-酚醛网络纳米平台用于改善新生血管性年龄相关性黄斑变性

      A boronate-phenolic network nanoplatform carrying dimethyl itaconate for ameliorating neovascular age-related macular degeneration.

4036. 利用可见-近红外高光谱成像结合特征波长选择和光谱响应分析对羊肉中鸡肉掺假进行定量检测

      Quantitative detection of chicken adulteration in lamb by VIS-NIR hyperspectral imaging with characteristic wavelength selection and spectral response analysis.

4037. 利用注意力增强深度学习方法对山药进行产地鉴别拉曼光谱分析

      Raman spectral analysis of Chinese yam for geographical origin discrimination using an attention-enhanced deep learning approach.

4038. 通过基于SERS的传感平台对患者血浆中的麻醉药物进行术中监测

      Intraoperative monitoring of anesthetic drugs in patient plasma via a SERS-based sensing platform.

4039. 雌性BALB/c小鼠对博来霉素诱导的急性肺损伤反应的表征

      Characterization of responses to bleomycin-induced acute lung injury in female BALB/c mice.

4040. 手持式近红外光谱用于检测金黄色葡萄球菌接种相关的人离体骨变化

      Handheld near-infrared spectroscopy for detecting staphylococcal inoculation-associated changes in ex vivo human bone.

4041. 通过多源光谱融合对生物活性成分进行效应关联筛选和快速定量预测的综合策略

      An integrative strategy for effect-linked screening and rapid quantitative prediction of bioactive constituents via multi-source spectral fusion.

4042. 一种载体套载体系统：将钙纳米颗粒封装于β-环糊精-多糖水凝胶中用于维替泊芬递送及原位骨肉瘤放射增敏

      A carrier-within-a-carrier system with calcium nanoparticles encapsulated in β-cyclodextrin-polysaccharide hydrogel for verteporfin delivery and radiosensitization in orthotopic osteosarcoma.

4043. 在患有I型十二指肠狭窄的恶性胆道梗阻患者中，使用5.9-Fr输送系统通过前视内窥镜经毛细血管放置多孔覆盖金属支架

      Transpapillary Placement of a Multihole Covered Metal Stent Using a 5.9-Fr Delivery System Through a Forward-viewing Endoscope in Malignant Biliary Obstruction With Type I Duodenal Stenosis.

4044. 成人肝细胞作为类器官的瞬时培养可改善工程肝移植

      Transient culture of adult human hepatocytes as organoids improves engineered liver engraftment.

4045. 炎症触发的纳米药物递送微针靶向致病性COX2内皮细胞介导的糖萼降解以改善银屑病

      {"_":"Inflammation-triggered nanodrug delivery microneedles targeting pathogenic COX2 endothelial cell-mediated glycocalyx degradation to ameliorate psoriasis.","sup":["+"]}

4046. 氧化应激、衰老、代谢、SIRT1与肠道菌群：认知丧失的神经心脏基础

      Oxidative stress, aging, metabolism, SIRT1, and the gut microbiota: the neurocardiac basis of cognitive loss.

4047. 轴向手性1,1'-联萘酚的区域选择性直接芳基化：连接几何形状对聚集诱导发射、手性光放大和自组装微谐振器的影响

      Regioselective direct arylation of axially chiral 1,1'-binaphthols: impact of linkage geometry on aggregation-induced emission, chiroptical amplification, and self-assembled microresonators.

4048. 超声诱导级联纳米酶催化增强肿瘤细胞焦亡和全身抗肿瘤免疫

      Ultrasound-induced cascade nanozyme catalysis for enhanced tumor cell pyroptosis and systemic anti-tumor immunity.

4049. 使用高光谱成像和机器学习对混合物中的单个固体废物进行量化

      Quantification of individual solid wastes from a mixture using hyperspectral imaging and machine learning.

4050. 蒸制通过调节肠-肝轴中的肠道菌群-胆汁酸-FXR/NF-κB信号传导降低何首乌肝毒性

      Steaming reduces Polygonum multiflorum hepatotoxicity by modulating gut microbiota-bile acid-FXR/NF-κB signaling in the gut-liver axis.

4051. 神经性疼痛的植物治疗候选物：卵巢螺旋杆菌提取物显示出镇痛作用和良好的急性毒性特征

      A phytotherapeutic candidate for neuropathic pain: Helicteres ovata (Lam.) extract shows antinociceptive effects and favorable acute toxicity profile.

4052. 苯环连接的双氨基酸的不对称合成：CD/UV研究、DNA和血清白蛋白结合以及MCF-7细胞毒性

      Benzene-linked bis-amino acids via asymmetric synthesis: CD/UV studies, DNA and serum albumin binding, and MCF-7 cytotoxicity.

4053. GPC-net：一种用于小样本FTIR光谱定量的生成增强预测-校正神经网络及其在硬膜下血肿损伤时间中的应用

      GPC-net: a generative-augmented predictive-corrective neural network for small-sample FTIR spectral quantification with application to subdural hematoma injury time.

4054. 旁分泌信号和硫酸化低聚糖复合物对上皮间充质细胞伴侣的调节

      Regulation of epithelial-mesenchymal cell-cell partners by complexes of paracrine signals and sulfated oligosaccharides.

4055. 生物活性分子衍生的共价有机框架作为生物相容性支架用于酒精性肝病中靶向抑制AKR1B10

      Bioactive molecule-derived covalent organic frameworks as biocompatible scaffolds for targeted AKR1B10 inhibition in alcoholic liver disease.

4056. 水稻OsNrx3基因的第一个内含子OsNrx3i1作为合成启动子工程的候选内含子介导增强元件的特征

      {"_":"Characterization of , the first intron of rice gene, as a candidate intron-mediated enhancement element for synthetic promoter engineering.","i":["OsNrx3i1","OsNrx3"]}

4057. 筋骨草有机和水性叶、茎和根提取物的体内抗疟疾活性和急性毒性。-火腿。前D.唐

      In vivo antimalarial activity and acute toxicity of organic and aqueous leaf, stem and root extracts of Ajuga integrifolia Buch.-Ham. ex D. Don.

4058. 健脾补肾清肠化瘀方通过丁酸相关HDAC1抑制和Th17/Treg稳态缓解DSS诱导的结肠炎

      Jianpi Bushen Qingchang Huashi formula alleviates DSS-induced colitis through butyrate-associated HDAC1 inhibition and Th17/Treg homeostasis.

4059. 1-脱氧野尻霉素通过PI3K/AKT介导的线粒体保护和抗凋亡减轻糖尿病心肌病

      1-Deoxynojirimycin attenuates diabetic cardiomyopathy via PI3K/AKT-mediated mitochondrial protection and anti-apoptosis.

4060. 结核病治疗的进展：新的治疗方案、新的药物管道、宿主导向疗法和更新的管理指南

      Advances in tuberculosis treatment: novel regimens, new drug pipelines, host-directed therapies, and updated management guidelines.

4061. 结核病诊断和生物标志物的进展，2020-26：科学证据、建议、差距和发展优先事项

      Advances in tuberculosis diagnostics and biomarkers, 2020-26: scientific evidence, recommendations, gaps, and developmental priorities.

4062. 结核病疫苗和预防性药物疗法的开发进展：目前的管道、证据和获取

      Advances in development of tuberculosis vaccines and preventive drug therapies: current pipeline, evidence, and access.

4063. 全球结核病流行状况：疾病负担、实现世卫组织终止结核病战略目标的进展及系统性挑战

      State of the global tuberculosis epidemic: burden, progress towards WHO End TB Strategy targets and systemic challenges.

4064. 机器学习赋能的表面增强拉曼光谱定量分析用于食品安全监测

      Machine learning enabled surface-enhanced Raman spectroscopy quantitative analysis for food safety monitoring.

4065. 增强压电胶原蛋白，具有对齐的微观结构，用于协同电拓扑骨骼肌再生

      Enhanced piezoelectric collagen with aligned microstructure for synergistic electro-topological skeletal muscle regeneration.

4066. 在Billroth II式重建伴肿瘤相关变形中，使用S-O夹进行牵引辅助内镜逆行胰胆管造影术用于困难胆管插管

      Traction-assisted Endoscopic Retrograde Cholangiopancreatography Using an S-O Clip for Difficult Biliary Cannulation in Billroth II Reconstruction With Tumor-associated Distortion.

4067. 关联彩色成像在早期癌症人工智能辅助诊断中的益处：倾向性评分调整的初步研究

      Benefit of Linked-Color Imaging in Artificial Intelligence-Assisted Diagnosis of Early Gastric Cancer: A Pilot Study With Propensity Score Adjustment.

4068. 真武汤改善实验性良性前列腺增生：与线粒体质量控制、氧化应激和凋亡调节有关

      Zhenwu Decoction ameliorates experimental benign prostatic hyperplasia: association with mitochondrial quality control, oxidative stress and apoptosis regulation.

4069. 利用高光谱成像和机器学习快速检测番茄表面农药残留

      Rapid detection of pesticide residues on tomato surfaces using hyperspectral imaging and machine learning.

4070. 使用多通吸收光谱对健康和胃病队列的N₂O呼气光谱进行确定性基线校正和线型建模

      Deterministic baseline correction and line-shape modeling for N₂O breath spectra from healthy and gastric-disease cohorts using multi-pass absorption spectroscopy.

4071. 合成多肽佐剂-抗生素联合用药可根除多微生物组装体、休眠细菌和细菌生物膜

      Synthetic polypeptide adjuvant-antibiotic combination eradicates polymicrobial assemblies, dormant bacteria and bacterial biofilm.

4072. 超小型纳米单催化剂诱导泛光症以抑制卵巢癌症：从患者来源的类器官到体内模型

      Ultrasmall nanosonocatalyst induces PANoptosis to suppress ovarian cancer: From patient-derived organoids to in vivo models.

4073. 分阶段疫苗接种运动的最佳时机：基于情景树的随机优化的启示

      Optimal timing for staged vaccination campaigns: Insights from scenario tree-based stochastic optimization.

4074. 核磁共振的人工智能前景

      The perspective of artificial intelligence for NMR.

4075. 固态核磁共振在研究金属有机框架中的应用和未来发展

      Applications and future development of solid-state nuclear magnetic resonance for investigating metal-organic frameworks.

4076. 用于筛选活细胞中抗癌剂的谷氨酰胺代谢的实时NMR分析

      Real-time NMR analysis of glutamine metabolism for screening anti-cancer agents in living cells.

4077. 揭示金鸡菊的皮肤保护材料基础。：民族药理学使用配体钓鱼方法指导多靶点酶抑制剂的发现

      Unveiling the skin-protective material basis of Coreopsis tinctoria Nutt.: Ethnopharmacology-Guided discovery of multi-target enzyme inhibitors using a ligand-fishing approach.

4078. {“_”：“结联草的UHPLC-MS/MS和GC-MS筛选及其对四氯化碳（CCl）诱导的HepG2细胞抗氧化应激和凋亡的补救作用。”，“sub”：[“4”]}

      {"_":"UHPLC-MS/MS and GC-MS screening of Synedrella nodiflora (L.) Gaertn. and its remedial effect in carbon tetrachloride (CCl)-induced HepG2 cells against oxidative stress and apoptosis.","sub":["4"]}

4079. 柴蒲汤在实验模型中的平喘作用：化学分析、探索性网络药理学和NLRP3/Caspase-1/GSDMD相关焦亡信号的评估

      Anti-asthmatic effects of Chai-Po-Tang in experimental models: chemical profiling, exploratory network pharmacology, and assessment of NLRP3/Caspase-1/GSDMD-related pyroptosis signaling.

4080. 肉桂水提取物对斑马鱼（Danio rerio）的胚胎毒性和致畸性：浓度依赖性发育毒性评估

      Embryotoxicity and teratogenicity of the aqueous extract of Cinnamomum verum in zebrafish (Danio rerio): a concentration-dependent developmental toxicity assessment.

4081. 桑叶黄酮通过重塑肠道微生物群胆汁酸轴和激活FXR信号传导来缓解2型糖尿病

      Mulberry leaf flavonoids alleviate type 2 diabetes by remodeling the gut microbiota-bile acid axis and activating FXR signaling.

4082. 超声门控纳米气泡用于脓毒症相关脑病中序贯性细胞焦亡阻断与机械转导神经修复

      Ultrasound-gated nanobubbles for sequential pyroptosis blockade and mechanotransductive neurorepair in sepsis-associated encephalopathy.

4083. 病理驱动的催化纳米酶集成黏附水凝胶打破高血糖-活性氧-缺氧循环以加速糖尿病血管化骨折愈合

      Pathology-driven catalytic nanozyme-integrated adhesive hydrogel disrupts the hyperglycemia-ROS-hypoxia loop to accelerate vascularized fracture healing in diabetes.

4084. 通过从头设计为凝析油状组件设计短序列元件

      Engineering short-sequence elements for condensate-like assemblies by de novo design.

4085. 用于改善心律失常患者心脏黑血和PSIR MRI质量的新脉冲序列

      New pulse sequence for improving cardiac black-blood and PSIR MRI quality in cases of arrhythmia.

4086. 使用miRNA和机器学习对阿尔茨海默病、路易体痴呆和额颞叶痴呆的比较筛查

      Comparative Screening of Alzheimer's Disease, Lewy Body Dementia, and Frontotemporal Dementia Using miRNA and Machine Learning.

4087. 肉苁蓉水提取物缓解功能性便秘的机制性见解：肠道微生物群重塑和与局部粘附相关的粘膜修复的整合

      Mechanistic insights into Cistanche deserticola aqueous extract in alleviating functional constipation: Integration of gut microbiota remodeling and focal adhesion-associated mucosal repair.

4088. 免疫调节性PanDR和SARS-CoV-2受体结合域抗原在细菌宿主细胞中的表达及免疫测定评估

      Expression and immunoassay assessment of immunomodulatory PanDR and SARS-CoV-2 receptor-binding domain antigen in bacteria host cell.

4089. 大建中汤通过肠道菌群-胆汁酸轴恢复腹泻型肠易激综合征大鼠的肠脑平衡

      Da-Jian-Zhong decoction restores the gut-brain balance in diarrhea-predominant irritable bowel syndrome rats via gut microbiota-bile acid axis.

4090. 唇形科植物对代谢综合征患者人体测量指标的影响：随机临床试验的系统评价与荟萃分析

      Impact of lamiaceae plants on anthropometric indices in patients with metabolic syndrome: A systematic review and meta-analysis of randomized clinical trials.

4091. 整合多组学和网络药理学于系统方法中：人参来源的Panaxadiol皂苷抗免疫介导的再生障碍性贫血的机制研究

      Integrating multi-omics and network pharmacology in a systems approach: a mechanism study of ginseng-derived panaxadiol saponins against immune-mediated aplastic anemia.

4092. 槟榔原花青素通过抑制TGF-β/Smad/ERK级联反应缓解肺纤维化：一种传统草药的验证

      Areca catechu L. procyanidins alleviate pulmonary fibrosis by suppressing the TGF-β/Smad/ERK cascade: Validation of a traditional herbal medicine.

4093. 加味舒郁丸通过调节海马信号传导和脂质代谢铁下垂轴改善脑缺血再灌注损伤

      Jiajian Shuyu Pills ameliorates cerebral ischemia-reperfusion injury by regulation hippo signaling and the lipid metabolism-ferroptosis axis.

4094. 重新审视PSMA介导的纳米载体肿瘤靶向性并增强PARP/EZH2抑制剂的共递送以实现有效的前列腺癌治疗

      Rethinking the PSMA-mediated tumor targeting of nanocarrier and potentiating co-delivery of PARP/EZH2 inhibitors for robust prostate cancer treatment.

4095. 均值回归环境噪声下具有潜伏细胞激活的HIV模型的随机阈值动力学

      Stochastic threshold dynamics of an HIV model with latent cell activation under mean-reverting environmental noise.

4096. 基于LC-MS分析、网络药理学和实验验证的升麻抗哮喘成分和机制研究

      Investigation of anti-asthmatic constituents and mechanisms of Cimicifugae Rhizoma based on LC-MS analysis, network pharmacology and experimental validation.

4097. 在低覆盖率测序数据中优化IBD片段推断和基因分型准确性的硬截止质量控制指标

      Optimizing hard cutoff quality control metrics for IBD segment inference and genotyping accuracy in low-coverage sequencing data.

4098. 减轻自动化错误期间的心理不适：一项混合方法研究

      Mitigating psychological discomfort during automation error: A mixed methods research.

4099. Platycodin D通过调节MAPK、NLRP3炎性体和干扰素信号传导来限制NDV的复制

      Platycodin D restricts NDV replication via modulation of MAPK, NLRP3 inflammasome and interferon signaling.

4100. Serenoa repens提取物上市后的安全性和潜在的阿司匹林相互作用：一项使用FAERS和网络毒理学的真实世界研究

      Post-marketing safety profile and potential aspirin interaction of Serenoa repens extract: A real-world study using FAERS and network toxicology.

4101. 基于锚点的快速平衡多视图聚类

      Anchor-based fast balanced multi-view clustering.

4102. 基于机器学习分类器的统一多类脑电图伪迹识别

      Unified Multi-Class Electroencephalogram Artifact Recognition Using Machine Learning Classifiers.

4103. 中国紫茎泽兰A通过靶向JAK2/STAT1通路和重塑肠道微生物群来缓解DSS诱导的溃疡性结肠炎和肠肝轴紊乱

      Callistephus A from Callistephus chinensis alleviates DSS-induced ulcerative colitis and gut-liver axis disruption by targeting the JAK2/STAT1 pathway and remodeling gut microbiota.

4104. 舒心口服液减轻异丙肾上腺素诱导的大鼠心肌纤维化：与TGF-β/Smad信号通路下调有关

      Shuxin oral liquid attenuates isoproterenol-induced myocardial fibrosis in rats: Association with downregulation of the TGF-β/Smad signaling pathway.

4105. 脉络舒通丸通过协调线粒体吞噬清除和铁蛋白抑制来缓解股骨骨折大鼠的肢体肿胀

      Mailuo Shutong pills alleviate limb swelling in femoral fracture rats by orchestrating mitophagic clearance and ferroptotic suppression.

4106. Calycinum Benth.-水蓼 L. 通过自噬激活和凋亡抑制对胃黏膜损伤的胃保护作用

      Gastroprotective effect of Daphniphyllum calycinum Benth.-Polygonum hydropiper L. against gastric mucosal injury through autophagy activation and apoptosis suppression.

4107. 马甲子提取物部分改善AOM/DSS诱导的小鼠结肠炎相关结直肠癌：来自转录组学和肠道菌群分析的见解

      Paliurus ramosissimus extract partially ameliorates AOM/DSS-induced colitis-associated colorectal cancer in mice: insights from transcriptomic and gut microbiota analyses.

4108. 针对凋亡细胞外囊泡的可注射水凝胶微球的工程衰老，减轻髓核细胞铁下垂对椎间盘退变的影响

      Engineered senescence-targeting apoptotic extracellular vesicles-laden injectable hydrogel microspheres mitigating nucleus pulposus cell ferroptosis against intervertebral disc degeneration.

4109. 人工智能驱动的生物分子设计：模态、模型与转化

      AI-driven biomolecular design: Modalities, models, and translation.

4110. 效力与覆盖率：疫苗接种计划对人口的影响

      Efficacy versus coverage: population-level impacts of vaccination schemes.

4111. 将低氧化石墨烯掺入静电纺聚（ε-己内酯）/明胶支架用于人胚胎干细胞来源的视网膜色素上皮细胞移植

      Incorporation of low-oxidation graphene oxide into electrospun poly(ε-caprolactone) /gelatin scaffolds for human embryonic stem cell-derived retinal pigment epithelium cell transplantation.

4112. {"_":"作为一种多功能益生菌用于炎症性肠病：机制、合生元策略和递送系统。","i":["植物乳杆菌"]}

      {"_":" as a multifunctional probiotic for inflammatory bowel disease: Mechanisms, synbiotic strategies, and delivery systems.","i":["Lactiplantibacillus plantarum"]}

4113. 银杏叶提取物50通过阻断早老素1/2条件双敲除小鼠的ATP-P2X7R轴来抑制神经炎症，从而缓解记忆和突触可塑性缺陷

      Ginkgo biloba extract 50 alleviates memory and synaptic plasticity deficits by inhibiting neuroinflammation via the blockage of ATP-P2X7R axis in presenilin 1/2 conditional double knockout mice.

4114. 可注射水凝胶介导的亚精胺递送通过氧化代谢触发肿瘤细胞焦亡以增强癌症治疗

      Injectable hydrogel-mediated spermidine delivery triggers tumor pyroptosis via oxidative metabolism for enhanced cancer therapy.

4115. 虎杖苷通过调节BMAL1来改善线粒体动力学节律紊乱，以预防和治疗代谢功能障碍相关的脂肪肝疾病

      Polydatin improves mitochondrial dynamics dysrhythmia by regulating BMAL1 to prevent and treat metabolic dysfunction-associated fatty liver disease.

4116. 自愈合药物支架水凝胶的原位工程化构建以阻断血小板驱动的术后转移

      In situ engineering of a self-healing drug-scaffold hydrogel to block platelet-driven postoperative metastasis.

4117. 用于增强缺血性卒中干细胞治疗的生物材料平台

      Biomaterial platforms for enhanced stem cell therapy in ischemic stroke.

4118. Chebulinic acid通过ACLY介导的脂质代谢重编程抑制NF-κB/TSLP信号轴，以改善特应性皮炎

      Chebulinic acid suppresses NF-κB/TSLP signaling axis via ACLY-mediated lipid metabolism reprogramming to ameliorate atopic dermatitis.

4119. 一种用于人群暴露组全关联研究中血清化学混合物分析的新型靶向高通量工作流程

      A novel targeted high-throughput workflow for serum chemical mixture profiling in population exposome-wide association studies.

4120. 肿瘤微环境响应性自组装纳米疗法，整合化疗、抗血管生成和免疫刺激疗法治疗癌症三阴性乳腺癌

      Tumor microenvironment-responsive self-assembling nanotherapeutics integrating chemo-, anti-angiogenic, and immunostimulatory therapy for triple-negative breast cancer.

4121. 通过双智能体大语言模型框架实现高效且可泛化的文本数据集蒸馏

      Toward Efficient and Generalizable Text Dataset Distillation via a Dual-Agent Large Language Model Framework.

4122. 三味杜鹃方通过调节MAPK信号通路改善缺氧性肺损伤

      San-Wei-Du-Juan formula ameliorates hypoxic lung injury by regulating the MAPK signaling pathway.

4123. 昆葵保肾颗粒通过SIRT3/FOXO3a信号通路减轻糖尿病肾病：综合多组学分析

      Kunkui Baoshen Granule attenuates diabetic kidney disease via the SIRT3/FOXO3a signaling pathway: An integrated multi-omics analysis.

4124. 基于异配位钌（II）配合物的声催化剂触发gasdermin D棕榈酰化，以增强耐缺氧的非经典焦亡免疫疗法

      Heteroleptic ruthenium(II) complexes-based sonocatalysts trigger gasdermin D palmitoylation to augment hypoxia-resistant non-canonical pyroptotic immunotherapy.

4125. 益气活血方通过抑制NF-κB p65/NLRP3炎症小体相关的焦亡信号来改善子宫内膜异位症

      Yiqi Huoxue Formula ameliorates endometriosis by suppressing NF-κB p65/NLRP3 inflammasome-associated pyroptotic signaling.

4126. 急性肺损伤中的短链脂肪酸代谢及中医干预策略

      Short-chain fatty acid metabolism in acute lung injury and intervention strategies from traditional Chinese medicine.

4127. 姜黄素在MASLD动物模型中的最佳剂量窗口、制剂疗效及分子机制：系统评价与三水平荟萃分析

      Optimal dose window, formulation efficacy, and molecular mechanisms of curcumin in MASLD animal models: A systematic review and three-level meta-analysis.

4128. 过表达PTGFRN和IL-4的外泌体功能化Janus纤维支架用于增强异质性组织再生

      PTGFRN- and IL-4-overexpressing exosome-functionalized Janus fibrous scaffolds for enhanced heterogeneous tissue regeneration.

4129. 脂蛋白沉积策略构建细菌毒素触发的“吸附-成孔-免疫调节”级联反应智能微球用于脓毒症治疗

      Lipo-protein deposition strategy towards smart microspheres with bacterial toxin triggered "adsorption-pore formation-immune regulation" cascade reaction for sepsis treatment.

4130. 整合老年患者肺部微生物组、氨基酸代谢和宿主免疫反应，用于严重下呼吸道感染的诊断：一项多组学研究

      Integrating lung microbiome, amino acid metabolism, and host immune response in elderly patients for severe lower respiratory Infections diagnosis: a multi-omics study.

4131. 靶向脂质纳米颗粒上的细胞因子共呈递增强了体内T细胞工程

      Cytokine co-presentation on targeted lipid nanoparticles enhances in vivo T cell engineering.

4132. 利用普通小球藻来源的细胞外囊泡增强癌症免疫治疗

      Harnessing Chlorella vulgaris-derived extracellular vesicles for potentiated cancer immunotherapy.

4133. 能量响应型多催化纳米发电机水凝胶通过年龄/RAGE/PIEZO2轴协同增强糖尿病肌腱到骨的愈合

      Energy-responsive multi-catalytic nanogenerator hydrogels synergistically enhance diabetic tendon-to-bone healing via the ages/RAGE/PIEZO2 axis.

4134. 纳米酶催化的双电位电化学发光免疫传感器，用于同时检测作为肺癌生物标志物的CEA和NSE

      Nanozyme-catalyzed dual-potential electrochemiluminescence immunosensor for simultaneous detection of CEA and NSE as lung cancer biomarkers.

4135. 机器学习辅助的光电化学适配体传感器利用BiOBr/SrWO S型异质结监测纳布啡

      {"_":"Machine learning-assisted photoelectrochemical aptasensor for nalbuphine monitoring using a BiOBr/SrWO S-scheme heterojunction.","sub":["4"]}

4136. 多组学揭示地黄的作用机制。用阳春砂仁加工而成。治疗血虚综合征

      Multi-omics reveals the mechanism of Rehmannia glutinosa Libosch. Processed with Amomum villosum Lour. in treating blood deficiency syndrome.

4137. 游离DNA甲基化检测技术的创新进展与临床应用

      Innovative advances and clinical applications of cell-free DNA methylation detection technologies.

4138. 深度学习驱动的PET水解酶协同工程，用于消费后PET解聚

      Deep Learning-driven synergistic engineering of PET hydrolase for post-consumer PET depolymerization.

4139. 葛根-枳实-草药对通过PI3K/AKT/mTO通路双重调节IL-11驱动的炎症和恢复脂质稳态来改善急性酒精性肝损伤

      Flos Puerariae-Semen Hoveniae herb pair ameliorates acute alcohol-induced liver injury by dual-modulating IL-11-driven inflammation and restoring lipid homeostasis via the PI3K/AKT/mTO pathway.

4140. 地榆黄连散抗乙醇性胃损伤的血清药物化学综合评价：山奈酚和PI3K/AKT信号的参与

      Integrated serum pharmacochemistry-guided evaluation of Diyu Huanglian San against ethanol-induced gastric injury: involvement of kaempferol and PI3K/AKT signaling.

4141. 日本金丝桃。ex Murray通过TF/FVIIa介导的信号通路抑制肝细胞癌血管生成

      Hypericum japonicum Thunb. ex Murray inhibits hepatocellular carcinoma angiogenesis through the TF/FVIIa-mediated signaling pathway.

4142. 基于高光谱成像的双任务可学习光谱掩膜卷积神经网络用于川贝母粉的分级掺假检测

      Hyperspectral imaging-based dual-task learnable spectral mask convolutional neural network for hierarchical adulteration detection in Fritillaria (Beimu) powder.

4143. 上消化道出血患者临床管理中大型语言模型的评估：来自现实世界患者数据的见解

      Evaluation of Large Language Models in the Clinical Management of Patients With Upper Gastrointestinal Bleeding: Insights From Real-World Patient Data.

4144. 人肺型恶丝虫病中角质层形态的异常表现

      Unusual aspect of cuticular morphology in human pulmonary dirofilariasis.

4145. 羊肉脂肪加工通过调节代谢炎症骨轴增强淫羊藿的抗骨质疏松作用

      Mutton fat-processing enhances the anti-osteoporotic effect of Epimedium koreanum Nakai via regulating the metabolism-inflammation-bone axis.

4146. Orientin通过ROS/HIF-1α/GLUT1信号轴调节铁下垂和糖酵解来缓解溃疡性结肠炎

      Orientin alleviates ulcerative colitis by regulating ferroptosis and glycolysis via the ROS/HIF-1α/GLUT1 signaling axis.

4147. 含羞草（Mimosa gemmulata）精油依赖IL-10的抗伤害感受和抗炎效应的机制研究

      Mechanistic insights into IL-10-dependent antinociceptive and anti-inflammatory effects of Mimosa gemmulata essential oil.

4148. 无标记表面增强拉曼光谱与机器学习用于牛呼吸道疾病综合征病毒的快速分类和定量

      Label-free surface-enhanced Raman spectroscopy and machine learning for rapid classification and quantification of bovine respiratory disease complex viruses.

4149. 解码生化指纹：人工智能赋能的拉曼光谱用于快速表型抗菌药物敏感性测试

      Decoding biochemical fingerprints: Artificial intelligence-empowered Raman spectroscopy for rapid phenotypic antimicrobial susceptibility testing.

4150. 一种用于超灵敏电化学CEA检测的基于双互穿导电水凝胶的3D免疫界面

      A dual interpenetrating conductive hydrogel based 3D immunointerface for ultrasensitive electrochemical CEA detection.

4151. 基于多源数据融合和机器学习算法的菊花快速鉴别

      Rapid identification of Chrysanthemi Flos based on multi-source data fusion and machine learning algorithms.

4152. 用于SARS-CoV-2疫苗接种的淋巴结靶向mRNA递送精细调节肽-纳米复合物

      Lymph node-targeted mRNA delivery of fine-tuned peptide-nanocomplexes for SARS-CoV-2 Vaccination.

4153. 生化、激素及凝血检测的个性化参考区间：与基于人群的参考区间的比较

      Personalized reference intervals for biochemical, hormonal, and coagulation tests: Comparison with population-based reference intervals.

4154. 白术乙醇提取物的预防性给药。减轻金黄色葡萄球菌诱导的小鼠肺肠损伤：与传统除湿用途相关的解释性药理学证据

      Preventive administration of ethanol extract of Atractylodes lancea (Thunb.) DC. attenuates Staphylococcus aureus-induced lung-gut injury in mice: explanatory pharmacological evidence related to its traditional dampness-resolving use.

4155. 番荔枝果肉水溶性多糖对LPS诱导的斑马鱼胚胎的抗炎作用：网络药理学指导分析和实验验证

      Anti-inflammatory effects of water-soluble polysaccharides from Annona squamosa L. pulp in LPS-induced zebrafish embryos: Network pharmacology-guided analysis and experimental validation.

4156. 刺山柑在胃肠道和呼吸系统疾病中的民族药理学验证：来自体外、体内和计算机模型的证据

      Ethnopharmacological validation of Capparis spinosa L. in gastrointestinal and respiratory disorders: Evidence from in vitro, in vivo, and in silico models.

4157. 人气道来源的脱细胞细胞外基质水凝胶的表征及其对气道上皮细胞生长、组织和分化的影响

      Characterization of human airway-derived decellularized extracellulr matrix hydrogels and their effects on airway epithelial cell growth, organization and differentiation.

4158. 基因编程工程纳米器件触发AMPK和cGAS-STING激活之间的级联增强，用于结肠癌癌症声免疫疗法

      Genetically programmed engineered nanodevices trigger cascade reinforcement between AMPK and cGAS-STING activation for colon cancer sonoimmunotherapy.

4159. 机器学习赋能的无标记SERS微生物传感：迈向稳健、可泛化且可部署的工作流程

      Machine learning-enabled label-free SERS for microbial sensing: Toward robust, generalizable, and deployable workflows.

4160. 使用带有4臂-PEG隔离层石墨烯晶体管生物传感器特异性检测生物流体中的蛋白质

      Specific detection of protein in biofluids using graphene transistor biosensors with a 4arm-PEG isolation layer.

4161. 通过化学分析、有效性评估和仿生传感，在五原则框架下对菝葜候选质量标志物进行综合优先级排序

      Integrated prioritization of candidate quality markers for Smilacis Chinae Rhizoma under the five-principle framework through chemical profiling, effectiveness evaluation, and bionic sensing.

4162. 20,205名中国个体癌症易感基因次要发现的随访队列研究

      A follow-up cohort study on secondary findings in cancer predisposition genes from 20,205 Chinese individuals.

4163. 机器学习引导的协同多尺寸水凝胶微球设计用于骨关节炎治疗

      Machine learning-guided design of cooperative multi-size hydrogel microspheres for osteoarthritis therapy.

4164. Tubuloside A通过抑制NOX4相关的氧化应激、炎症、凋亡和线粒体功能障碍来减轻脓毒症诱导的小鼠脾损伤

      Tubuloside A mitigates sepsis-induced splenic injury in mice by suppressing NOX4-associated oxidative stress, inflammation, apoptosis, and mitochondrial dysfunction.

4165. 大獐牙菜治疗5-氟尿嘧啶诱导的腹泻的植物化学基础和机制见解

      Phytochemical basis and mechanistic insight of Swertia macrosperma in treating 5-fluorouracil-induced diarrhea.

4166. 基于高光谱成像辅助机器学习的西洋参微塑料胁迫生理响应检测及跨器官表征

      Detection and cross-organ characterization of physiological response to microplastic stress in Panax ginseng based on hyperspectral imaging assisted with machine learning.

4167. 基于CRISPR的ESKAPE耐药细菌诊断：从概念验证到即时检测

      CRISPR-based diagnostics for ESKAPE drug-resistant bacteria: From proof-of-concept to point-of-care.

4168. 鉴定枯草芽孢杆菌无质粒微生物细胞工厂开发的整合位点库

      {"_":"Identification of integration site library for the development of plasmid-free microbial cell factory in .","i":["Bacillus subtilis"]}

4169. {"_":"在毕赤酵母中高效表达全长三螺旋重组III型胶原。","i":["Pichia pastoris"]}

      {"_":"Efficient expression of full-length triple-helix recombinant type III collagen in .","i":["Pichia pastoris"]}

4170. 使用全层切除装置进行结直肠内镜下全层切除的临床结局：一项多中心研究

      Clinical Outcomes of Colorectal Endoscopic Full-Thickness Resection Using the Full-Thickness Resection Device: A Multicenter Study.

4171. 黄柏总生物碱通过调节ER线粒体轴恢复肠屏障完整性来改善溃疡性结肠炎

      Cortex Phellodendri total alkaloids ameliorate ulcerative colitis by restoring intestinal barrier integrity via modulation of the ER-mitochondria axis.

4172. 在铜腙诱导的脱髓鞘模型中，西洋参皂苷通过协调HMGCS1-NPC1-MAL介导的脂质代谢和重新平衡JAK-STAT信号传导来促进髓鞘再生

      Panax quinquefolius saponins promote remyelination via orchestrating HMGCS1-NPC1-MAL-mediated lipid metabolism and rebalancing JAK-STAT signaling in a cuprizone-induced demyelination model.

4173. 天然产物和传统药物对RAGE的调节：为炎症性疾病开辟了有前景的前景

      The modulation of RAGE by natural products and traditional medicines: Opening promising perspectives for inflammatory diseases.

4174. Parinari cureallifolia水性树皮提取物通过抗炎和骨再生机制减轻了伯氏疟原虫诱导的Wistar大鼠慢性骨丢失

      Parinari curatellifolia aqueous leaf-bark extract mitigates chronic Plasmodium berghei-induced bone loss in Wistar rats through anti-inflammatory and osteoregenerative mechanisms.

4175. 推进核退役和拆除的安全培训：整合基于MX的方法以提高能力发展

      Advancing safety training for nuclear decommissioning and dismantling: Integrating MX-based approaches for improved competency development.

4176. 芎芷祛风止痛颗粒通过调控HMGB1/TRPV1/MAPK信号轴缓解硝酸甘油诱导的偏头痛样痛觉及中枢神经炎症

      Xiongzhi Qufeng Zhitong Granule alleviates nitroglycerin-induced migraine-like nociception and central neuroinflammation by regulating the HMGB1 / TRPV1 / MAPK signaling axis.

4177. 马尼氏小蠹乙酸乙酯提取物通过抑制细胞凋亡和抑制TLR4/NF-κB介导的神经炎症来改善缺血性中风

      Ethyl acetate extract of Poecilobdella manillensis Lesson ameliorates ischemia stroke through inhibiting cell apoptosis and suppressing TLR4/NF-κB-mediates neuroinflammation.

4178. 数据驱动方法可预测DNA返工实用性

      Data-driven methods allow prediction of utility of DNA rework.

4179. 铁路中的权威梯度：一项跨司法管辖区的系统评价与荟萃综合

      Authority gradients in rail: A cross-jurisdictional systematic review and meta-synthesis.

4180. 压力的分散注意力作用：执行注意力受损，疲劳感知延迟

      The distracting role of stress: Impaired executive attention and delayed fatigue perception.

4181. Ensaya：一种用于预测青少年和青年实际年龄的集成年龄模型

      Ensaya: An ensemble age model for prediction of chronological age in adolescents and young adults.

4182. 基于近红外高光谱成像与化学计量学的工业堆肥转化像素级评估：一种过程监测的早期预警工具

      Pixel-wise assessment of industrial compost transformation by NIR hyperspectral imaging and chemometrics: an early-warning tool for process monitoring.

4183. 机器学习辅助智能电化学平台：高灵敏度同时检测生物样本中的芦丁和木犀草素

      Machine learning-assisted smart electrochemical platform: High-sensitivity simultaneous detection of rutin and luteolin in biological samples.

4184. 在基于多糖的手性固定相上通过超临界流体色谱同时分离依折麦布及其七种立体异构体：优化与热力学分析

      Simultaneous separation of ezetimibe and its seven stereoisomers by supercritical fluid chromatography on a polysaccharide-based chiral stationary phase: Optimization and thermodynamic analysis.

4185. 绘制下一代佐剂免疫学的分析工具箱：表征技术和新兴趋势的文献计量分析（2006-2025）

      Mapping the analytical toolbox for next-generation adjuvant immunology: A bibliometric analysis of characterization techniques and emerging trends (2006-2025).

4186. 十二指肠壶腹肿瘤内镜乳头切除术后残留病例的额外治疗评估

      Evaluation of Additional Treatment for Residual Cases After Endoscopic Papillectomy of Duodenal Ampullary Tumors.

4187. 利用艾蒿中的一种新型合酶，在酿酒酵母中高效生产β-石竹烯

      {"_":"Highly efficient production of -caryophyllene in using a novel synthase from .","i":["β","Saccharomyces cerevisiae","Artemisia argyi"]}

4188. 三氟淫羊藿苷通过抑制铁下垂来上调脊髓α7nAChR，从而减轻由神经损伤引起的神经性疼痛

      Trifluoro-icaritin mitigates spared nerve injury-induced neuropathic pain by upregulating spinal α7nAChR through suppressing ferroptosis.

4189. 常规校正公式与基于机器学习的离子钙预测比较

      Comparing conventional correction formulas and machine learning-based prediction of ionized calcium.

4190. 单细胞质谱揭示由接触依赖性细胞间相互作用介导的代谢分歧

      Single-cell mass spectrometry reveals metabolic divergence mediated by contact-dependent cell-cell interactions.

4191. 通过基因组挖掘和体外生物合成从短芽孢杆菌B011中发现酪胺和胰酪胺的亮氨酸类似物

      {"_":"Discovery of leucine analogues of tyrocidines and tryptocidines from B011 through genome mining and biosynthesis.","i":["Brevibacillus brevis","in vitro"]}

4192. 胡椒（胡椒科）的代谢特征及其双重抗炎和抗尿结石作用

      Metabolic profiling of Piper regnellii (Piperaceae) and its dual anti-inflammatory and anti-urolithiatic effects.

4193. 人工智能在诊断软件中的应用：欧洲的验证、安全性和生命周期挑战

      Artificial intelligence in diagnostic software: validation, safety, and lifecycle challenges in Europe.

4194. 通过使用基因组尺度代谢模型的多组学综合分析，揭示视黄醇对细胞增殖的双相作用的关键分子网络

      Key molecular networks underlying retinol's biphasic effects on cell proliferation through multi-omics integrative analysis using genome-scale metabolic modeling.

4195. {“_”：“在沉香树中筛选萜类合酶导致发现沉香甾醇。”，“i”：[“云南沉香”]}

      {"_":"Terpene synthases screening in agarwood tree leads to the discovery of agarospirol.","i":["Aquilaria yunnanensis"]}

4196. 中药香素合胃颗粒治疗非糜烂性胃食管反流病合并肝胃郁热证：一项多中心、随机、双盲、安慰剂对照试验

      Chinese herbal medicine Xiangsu Hewei Granules in treating non-erosive gastroesophageal reflux disease with liver stomach stagnation heat syndrome: A multicentre, randomized, double-blind, placebo-controlled trial.

4197. 内镜超声引导下细针活检的有效性，并进行简化的宏观现场评估（附视频）

      Efficacy of Endoscopic Ultrasound-guided Fine Needle Biopsy With Simplified Macroscopic On-site Evaluation (With Video).

4198. 利用天然草本植物对抗铁死亡：对多囊卵巢综合征管理的意义

      Harnessing natural herbaceous plants against ferroptosis: Implications for managing polycystic ovary syndrome.

4199. Kisspeptin-10/基础LH比值可改善中枢性早熟和早熟的分化

      Kisspeptin-10/basal LH ratio improves differentiation of central precocious puberty and premature thelarche.

4200. Presepsin在脓毒症诊断和30天死亡率预测中优于传统生物标志物：一项在北非ICU队列中开展的多中心前瞻性研究

      Presepsin outperforms conventional biomarkers for Sepsis diagnosis and 30-day mortality prediction: A multicenter prospective study in a north African ICU cohort.

4201. 解码异喹啉生物碱的MSn裂解规则：一个全面的图谱

      {"_":"Decoding MS fragmentation rules of isoquinoline alkaloids: a comprehensive atlas.","sup":["n"]}

4202. RAA-CRISPR/Cas12a介导的SERS磁性生物传感器与便携式拉曼光谱仪相结合，用于快速、超灵敏地检测结节性皮肤病病毒

      RAA-CRISPR/Cas12a-mediated SERS magnetic biosensor combined with a portable Raman spectrometer for rapid and ultrasensitive detection of Lumpy skin disease virus.

4203. 用于手性LC-MS分离的柱串联技术可在复杂样品中解析三酰甘油对映异构体和区域异构体，无需流动循环

      Column coupling for chiral LC-MS separation resolves triacylglycerol enantiomers and regioisomers in complex samples without flow recycling.

4204. 用于食品安全的混合CQD传感器：MOF/MIP复合材料、AI集成及实际基质性能

      Hybrid CQD sensors for food safety: MOF/MIP composites, AI integration, and real-matrix performance.

4205. 一种机器学习辅助的防污策略用于提高电化学传感器的准确性

      A machine learning-helped antifouling strategy for improving the accuracy of electrochemical sensors.

4206. 过敏性疾病生物传感器：生物标志物检测与监测

      Biosensors for allergic diseases: Biomarker detection and monitoring.

4207. C反应蛋白作为出血性脑卒中的通用预后指标：脑出血与动脉瘤性蛛网膜下腔出血的荟萃分析

      C-reactive protein as a universal prognosticator in hemorrhagic stroke: a meta-analysis of intracerebral and aneurysmal subarachnoid hemorrhage.

4208. 处于可检测边缘的纳米塑料：分析极限、转变和对生物降解研究的影响

      Nanoplastics at the edge of detectability: Analytical limits, transformation, and implications for biodegradation studies.

4209. 桥本甲状腺炎患者循环网膜素-1和HMGB1水平

      Circulating omentin-1 and HMGB1 levels in patients with Hashimoto thyroiditis.

4210. 癌症中奥西妥西相关生物标志物的多组学分析

      Multi-omics profiling of oxeiptosis-associated biomarkers in cancer.

4211. 十二指肠金属和胆道塑料支架之间的机械联锁引起的小肠撞击

      Small-Bowel Impaction Caused by Mechanical Interlocking Between Duodenal Metal and Biliary Plastic Stents.

4212. 多发性I型胃神经内分泌肿瘤患者行胃窦切除术的临床结局：病例系列研究

      Clinical Outcomes of Antrectomy for Patients With Multiple Type I Gastric Neuroendocrine Tumors: A Case Series.

4213. 单形上趋性肠T细胞淋巴瘤患者空肠结肠瘘的内镜可视化

      Endoscopic Visualization of a Jejuno-Colonic Fistula in a Case of Monomorphic Epitheliotropic Intestinal T-Cell Lymphoma.

4214. 白球外观是异时性多发性胃癌的内镜预测因素

      White Globe Appearance Is an Endoscopic Predictor of Metachronous Multiple Gastric Cancers.

4215. 法医遗传学的下一个前沿：单细胞遗传分析及其不断扩大的作用

      The next frontier in forensic genetics: Single-cell genetic analysis and its expanding role.

4216. 鸢尾素作为慢性肾脏病中的多靶点肾脏保护介质：从分子机制到治疗前景

      Irisin as a multi-target renoprotective mediator in chronic kidney disease: from molecular mechanisms to therapeutic perspectives.

4217. 世界卫生组织对2000年至21年9种食源性化学品的全球、区域和国家疾病负担的估计：最新数据综合

      WHO estimates of the global, regional, and national disease burden of nine foodborne chemicals, 2000-21: an updated data synthesis.

4218. 多代母系家系线粒体DNA的遗传模式：线粒体全基因组测序的见解

      Inheritance patterns of mitochondrial DNA in multi-generational maternal pedigrees: Insights from mitochondrial whole-genome sequencing.

4219. 癌症BRAF突变的分子景观和先进诊断技术：从定量PCR和ddPCR到基于CRISPR-的平台

      Molecular Landscape and Advanced Diagnostic Technologies for BRAF Mutations in Cancer: From Quantitative PCR and ddPCR to CRISPR-Based Platforms.

4220. 腹腔镜手术中精神运动技能训练期间凝视行为的变化：一项纵向眼动追踪研究

      Changes in gaze behaviors during psychomotor skill training in laparoscopic surgery: A longitudinal eye tracking study.

4221. 个性化-隐私权衡如何影响Robotaxi adoption：来自移动第三空间的见解

      How personalization-privacy trade-offs influence Robotaxi adoption: Insights from mobile Third Places.

4222. 组织学幽门螺杆菌密度可能与中性粒细胞炎症活动的严重程度无关

      {"_":"Histological Density Might Not be Associated With the Severity of Neutrophilic Inflammatory Activity.","i":["Helicobacter pylori"]}

4223. 经口内镜下肌切开术中食管胃交界处的内镜伪扩张：（附视频）

      Endoscopic Pseudo-dilation of Esophagogastric Junction During Peroral Endoscopic Myotomy: (With Video).

4224. 化疗期间的最佳支架策略：首次介入时间对恶性肝门胆管梗阻患者生存率的影响

      Optimal Stenting Strategy During Chemotherapy: Impact of Time to First Reintervention on Survival in Malignant Hilar Biliary Obstruction.

4225. HER2低表达与HER2零表达早期乳腺癌的临床病理反应及生存结局：系统评价与荟萃分析

      Clinicopathological response and survival outcomes of HER2-low versus HER2-zero early breast Cancer: A systematic review and Meta-analysis.

4226. 巴西亚马逊地区的严重干旱以及结核病和艾滋病毒护理级联：对24年监测数据的贝叶斯结构间断时间序列分析

      Severe droughts and the tuberculosis and HIV care cascade in the Brazilian Amazon: a Bayesian, structural, interrupted time-series analysis of 24 years of surveillance data.

4227. 考察老年女性在自动驾驶汽车旅行中的压力

      Examining stress among older women during travel in autonomous vehicles.

4228. COSA：一种基于扩增子大规模平行测序的体液/组织来源、吸烟状况和实际年龄的综合甲基化预测面板

      COSA: A consolidated methylation-based prediction panel for body fluid/tissue of origin, smoking status, and chronological age using amplicon-based massively parallel sequencing.

4229. 评估临床语音AI模型的可解释性：来自两项用户研究的经验教训

      Evaluating the interpretability of clinical speech AI models: Lessons from two user studies.

4230. 在中枢和外周神经系统损伤中调节连接蛋白的气体传递子

      Gasotransmitters in the regulation of connexins in central and peripheral nervous system injuries.

4231. 人工智能时代的高压氧：整合与创新

      Hyperbaric oxygen in the artificial intelligence era: integration and innovation.

4232. 胃肠道快速进展惰性T细胞淋巴瘤病例报告

      Case Report of a Rapidly Progressive Indolent T-Cell Lymphoma of the Gastrointestinal Tract.

4233. 内镜超声引导下使用塑料支架进行肝胃吻合术中纤维吻合形成的机制：来自肝门周围胆管癌尸检病例的见解

      Mechanism of Fibrotic Anastomosis Formation in Endoscopic Ultrasound-guided Hepaticogastrostomy Using a Plastic Stent: Insights From an Autopsy Case of Perihilar Cholangiocarcinoma.

4234. 使用开源人工智能模型SEE-AI提高小肠胶囊内窥镜的效率和损伤检测

      Improved Efficiency and Lesion Detection in Small Bowel Capsule Endoscopy Using the Open-Source Artificial Intelligence Model SEE-AI.

4235. 慢性髓系白血病患者延迟性胃出血：活检后出血病例

      Delayed Gastric Bleeding in a Patient With Chronic Myeloid Leukemia: A Case of Post-Biopsy Bleeding.

4236. 预包装低残留饮食“透明”减少结肠镜检查所需的聚乙二醇溶液体积：一项探索性随机对照研究

      Prepackaged Low-Residue Diet "Clear-Through" Reduces the Required Volume of Polyethylene Glycol Solution for Colonoscopy Preparation: An Exploratory Randomized Controlled Study.

4237. 癌症内镜超声引导下细针穿刺治疗胃壁筛状纤维瘤模拟针道播种术一例报告。

      Desmoid Fibromatosis of the Gastric Wall Mimicking Needle Tract Seeding after Endoscopic Ultrasound-Guided Fine-Needle Biopsy for Pancreatic Cancer: A Case Report.

4238. 双重GLP-1/胰高血糖素受体激动在超重和肥胖症中的疗效和安全性：一项类别特异性系统评价和荟萃分析

      Efficacy and Safety of Dual GLP-1/Glucagon Receptor Agonism in Overweight and Obesity: A Class-Specific Systematic Review and Meta-Analysis.

4239. 临床神经生理学中的人工智能：IFCN手册章节

      Artificial intelligence in clinical neurophysiology: IFCN handbook chapter.

4240. 直肠癌伴腔内转移至十二指肠

      Rectal cancer with intraluminal metastasis to the duodenum.

4241. DO代谢标记结合AuNPs@PVP/SA水凝胶SERS平台用于活性乳酸菌的快速定量检测

      {"_":"DO metabolic labeling combined with AuNPs@PVP/SA hydrogel SERS platform for rapid quantitative detection of active lactic acid bacteria.","sub":["2"]}

4242. 帕立骨化醇减轻博来霉素诱导的肺纤维化：来自免疫组织化学和分子遗传学分析的见解

      Paricalcitol Attenuates Bleomycin-induced Pulmonary Fibrosis: Insights from Immunohistochemical and Molecular Genetic Analysis.

4243. 评估TikTok和哔哩哔哩上GLP-1受体激动剂健康信息的质量和可靠性：公共卫生信息疫情的横断面分析

      Assessing the quality and reliability of health information on GLP-1 receptor agonists on TikTok and Bilibili: a cross-sectional analysis of the public health infodemic.

4244. 前沿组织：外科肿瘤学中的共识知情框架

      Cutting-edge organization: A consensus-informed framework in surgical oncology.

4245. 多功能分子包封剂——环糊精：理化性质、安全性、溶解度、生物利用度及其在制药和食品中的应用

      Multifunctional molecular encapsulating agents - Cyclodextrins: Physicochemical properties, safety, solubility, bioavailability and applications in pharmaceuticals and foods.

4246. 着陆和切割任务中惯性测量单元对下肢关节角度的有效性和可靠性：系统综述和荟萃分析

      Validity and reliability of inertial measurement units on lower limb joint angles during landing and cutting tasks: A systematic review and meta-analysis.

4247. 全氟烷基化聚合物构建体绕过内体包埋，刺激增殖和非增殖细胞中的跨核递送

      Perfluoroalkylated polymeric constructs bypass endosomal entrapment to stimulate transnuclear delivery in proliferating and non-proliferating cells.

4248. 纳米纤维几何形状在最小二肽细胞外基质模型中指导癌症细胞增殖和侵袭

      Nanofiber geometry directs cancer cell proliferation and invasion in a minimalist dipeptide extracellular matrix model.

4249. 用于增强析氧反应的中间体功能化内源性质子中继体

      Intermediate functionalized endogenous proton relays for enhanced oxygen evolution reaction.

4250. Zn1Cu（1 1 1）单原子合金上CN偶联的机理研究

      {"_":"Mechanistic insights into CN coupling on ZnCu(1 1 1) single-atom alloy for electrocatalytic urea synthesis from CO and NO.","sub":["1"]}

4251. 具有催化抗氧化活性的Ru/CoMn-LDH@CTP纳米酶通过抑制脂质过氧化减轻心肌糖脂毒性

      Ru/CoMn-LDH@CTP nanozymes with catalytic antioxidant activity alleviate myocardial glucolipotoxicity through inhibition of lipid peroxidation.

4252. 成人ADHD的个体化结构与功能额纹状体连接映射

      Individualised Structural and Functional Frontostriatal Connectivity Mapping in Adult ADHD.

4253. 单次触发区刺激后的静息态局部脑功能同步：经典三叉神经痛患者中伴与不伴诱发性疼痛的比较

      Resting-state local brain functional synchronization after a single trigger-zone stimulation: with versus without evoked pain in classical trigeminal neuralgia patients.

4254. 约旦中部孕妇妊娠期贫血的患病率及危险因素

      Prevalence and Risk Factors of Maternal Anemia Among Pregnant Women in Central Jordan.

4255. 一种热力学有利的分子计算机

      A thermodynamically favoured molecular computer.

4256. 饲喂不同水平破碎红花籽的泌乳脂尾Turki-Qashqaei母羊的脂质利用效率及代谢反应

      Lipid utilization efficiency and metabolic responses in lactating fat-tailed Turki-Qashqaei ewes fed graded levels of cracked safflower.

4257. 睡眠时长和质量的性别差异：对高血压风险的影响

      Sex Differences in Sleep Duration and Quality: Implications for Hypertension Risk.

4258. 儿童炎症性肠病的营养监测与干预

      Nutritional Monitoring and Intervention in Paediatric Inflammatory Bowel Disease.

4259. 具有终末免疫耗竭表型的甲状腺乳头状癌与淋巴结转移风险增加相关：一项结合流式细胞术和TCGA的探索性研究

      Papillary Thyroid Carcinoma with Terminal Immune Exhaustion Phenotype Correlates with Increased Risk of Lymph Node Metastasis: An Exploratory Study Combining Flow Cytometry and TCGA.

4260. 杏仁核在睡眠与焦虑复杂关系中的作用

      Role of the Amygdala in the Complex Relationship Between Sleep and Anxiety.

4261. 可解释人工智能决策支持工具的临床可用性及多模态模型在非小细胞肺癌中的评估

      Clinical usability of an explainable AI decision support tool and evaluation of multimodal models in NSCLC.

4262. SGK2促进NEDD4L介导的ACSL4泛素化以抑制铁死亡并缓解糖尿病肾病

      SGK2 Promotes NEDD4L-Mediated ACSL4 Ubiquitination to Inhibit Ferroptosis and Alleviate Diabetic Kidney Disease.

4263. 手术室护士的患者安全能力：一项多中心横断面研究中与安全态度、系统思维和职业倦怠的关联

      Patient Safety Competency Among Operating Room Nurses: Associations With Safety Attitudes, Systems Thinking and Burnout in a Multicentre Cross-Sectional Study.

4264. 使用OrganoIDNet算法实时监测肿瘤患者来源类器官中CAR T细胞动态

      Real-time monitoring of CAR T cell dynamics in tumor patient-derived organoids using the OrganoIDNet algorithm.

4265. 灵芝与蛹虫草的发酵技术：工艺优化、生物活性化合物转化及功能性食品开发进展

      Fermentation technology of Ganoderma lucidum and Cordyceps militaris: advances in process optimization, bioactive compound transformation, and functional food development.

4266. 乳酸菌作为益生菌缓解牛疾病机制的最新研究：综述

      The current studies on the mechanisms of lactic acid bacteria as probiotics in the alleviate of bovine diseases: a review.

4267. 可视化未来：全息可视化对微创贴面预备教学的影响：一项随机对照试验

      Visualizing the future: impact of holographic visualization on teaching minimally invasive veneer preparation: a randomized controlled trial.

4268. MGAT5通过Nrf2/HO-1信号通路调控糖尿病肾病中的铁死亡

      MGAT5 regulates ferroptosis via the Nrf2/HO-1 signaling pathway in diabetic nephropathy.

4269. UCMamba：螺旋扫描和顺序对比学习溃疡性结肠炎严重程度评分的视觉状态空间模型

      UCMamba: Visual State Space Model for Ulcerative Colitis Severity Scoring with Spiral Scan and Sequential Contrastive Learning.

4270. [癌症]

      [Colorectal Cancer].

4271. 机器人辅助内镜黏膜下剥离的文献计量学绘图：研究趋势、协作网络和新兴主题

      Bibliometric mapping of robot-assisted endoscopic submucosal dissection: research trends, collaboration networks, and emerging themes.

4272. 当归芍药散对孕鼠孕酮撤退诱导的子宫炎症的免疫调节作用

      Immunomodulatory Effects of Tokishakuyakusan on Progesterone Withdrawal-Induced Uterine Inflammation in Pregnant Mice.

4273. 熵激增在硬碳中诱导短晶粒无序，实现超快钠储存

      Entropy surge induced short-crystallite disorder in hard carbon enabling ultrafast sodium storage.

4274. 用于类固醇激素分析的分子印迹聚合物：设计策略、识别机制及检测应用

      Molecularly Imprinted Polymers for Steroid Hormone Analysis: Design Strategies, Recognition Mechanisms, and Detection Applications.

4275. 基于胰高血糖素样肽-1的药物用于超重或肥胖非糖尿病成人减重的疗效和安全性比较：随机对照试验的网络荟萃分析

      Comparative efficacy and safety of glucagon-like peptide 1 based drugs for weight loss in adults with overweight or obesity without diabetes: network meta-analysis of randomised controlled trials.

4276. 四硫代钼酸铵通过NRF2-GPX4轴改善庆大霉素暴露后的听觉和前庭功能

      Ammonium tetrathiomolybdate improves auditory and vestibular function after gentamicin exposure via the NRF2-GPX4 axis.

4277. 缅甸义齿修复治疗的障碍与能力：一项横断面调查

      Barriers and Capacity for Prosthetic Dental Care in Myanmar: A Cross-sectional Survey.

4278. 免疫评分作为结直肠癌的预后标志物

      Immunoscore as a prognostic marker in colorectal cancer.

4279. 对CD40L错义变异A123E、S222F和G257R的计算分析预测X连锁高IgM综合征中CD40结合和三聚体稳定性发生改变

      Computational analysis of CD40L missense variants A123E, S222F, and G257R predicts altered CD40 binding and trimeric stability in X-linked hyper-IgM syndrome.

4280. 研究阿拉伯大学生对新冠肺炎疫苗犹豫和接受的决定因素：一项区域范围界定审查

      Examining determinants of COVID-19 vaccine hesitancy and acceptance among Arab university students: A regional scoping review.

4281. 表达FIPV刺突蛋白S1亚基的重组刚地弓形虫：针对弓形虫病和猫传染性腹膜炎的概念验证方法

      Recombinant Toxoplasma gondii expressing FIPV spike protein S1 subunit: A proof-of-concept approach against toxoplasmosis and feline infectious peritonitis.

4282. 瑞马唑仑联合艾司氯胺酮用于老年ERCP患者麻醉的安全性和有效性：一项随机对照试验

      Safety and Efficacy of Remimazolam Combined with Esketamine for Anesthesia in Elderly Patients Undergoing ERCP: A Randomized Controlled Trial.

4283. 可解释的机器学习能够早期识别结直肠癌癌症手术中的财务风险和资源优化

      Interpretable machine learning enables early identification of financial risk and resource optimization in colorectal cancer surgery.

4284. {"_":"复方改善失眠小鼠的睡眠结构并减轻海马损伤。","i":["夏枯草"]}

      {"_":" Compound Improves Sleep Architecture and Attenuates Hippocampal Injury in Insomnia Mice.","i":["Prunella vulgaris"]}

4285. 高血压中的数字健康素养与共享决策：自我效能感和患者激活的序列中介作用

      Digital health literacy and shared decision-making in hypertension: Sequential mediation by self-efficacy and patient activation.

4286. 非处方雾化曲安奈德在治疗造口周围坏疽性脓皮病中的应用：病例系列研究

      The use of over-the-counter aerosolized triamcinolone acetonide in the treatment of peristomal pyoderma gangrenosum: a case series.

4287. 用于过氧化氢深层组织成像的放射余辉纳米探针的合成

      Synthesis of radioafterglow nanoprobes for deep-tissue imaging of hydrogen peroxide.

4288. 微塑料和纳米塑料作为新兴的肠-脑轴干扰物：机制见解、健康影响和未来方向

      Microplastics and nano-plastics as emerging gut-brain axis disruptors: mechanistic insights, health implications, and future direction.

4289. 马兹度肽对肥胖或超重成年人的疗效和安全性：一项基于美国的多中心2期随机安慰剂对照临床试验

      Efficacy and safety of mazdutide in adults with obesity or overweight: a US-based, multicentre, phase 2, randomised, placebo-controlled clinical trial.

4290. 开发和评估基于人工智能的临床决策支持系统以优化乳腺多学科团队会议

      Development and evaluation of AI-based clinical decision support system for streamlining breast multidisciplinary team meetings.

4291. 鼠尾草素通过Nrf2介导的肾脏炎症和铁死亡调控减轻糖尿病肾病

      Salvigenin alleviates diabetic nephropathy through Nrf2-mediated modulation of renal inflammation and ferroptosis.

4292. 非酶糖基化转铁蛋白引起的铁过载通过调控PI3/AKT信号通路和Nrf2表达触发氧化应激和铁死亡，促进糖尿病肾损伤

      The iron overload caused by non-enzymatically glycated transferrin triggers oxidative stress and ferroptosis by regulating the PI3/AKT signalling pathway and the expression of Nrf2 to promote renal damage in diabetes.

4293. 用于锂硫电池的硫化钼：调控策略与催化化学综合评述

      Molybdenum Sulfides for Li-S Batteries: A Comprehensive Review of Modulation Strategies and Catalytic Chemistry.

4294. 梭杆菌属基因工程中规避限制-修饰系统的方法

      Methods for the Evasion of Restriction-Modification Systems During Genetic Engineering of Fusobacterium Species.

4295. 光老化聚氯乙烯微塑料通过TXNIP-NLRP3介导的炎症放大加重气道上皮屏障功能障碍

      Photoaged Polyvinyl Chloride Microplastics Aggravate Airway Epithelial Barrier Dysfunction via TXNIP-NLRP3-Mediated Inflammatory Amplification.

4296. 九种GLP-1受体激动剂的多重LC-HRMS方法的开发和验证及其药物应用

      Development and validation of a multiplexed LC-HRMS method for nine GLP-1 receptor agonists and its pharmaceutical application.

4297. 拓展ABCD1突变谱：X连锁肾上腺脑白质营养不良中的一个新变异

      Expanding the ABCD1 mutation spectrum: a novel variant in X-linked adrenomyeloneuropathy.

4298. 育龄期手术室医护人员对生殖危害的认知和保护经验：一项定性研究

      Perceptions and protective experiences regarding reproductive hazards among operating room healthcare workers of childbearing age: a qualitative study.

4299. 绝经过渡期与癫痫：聚焦治疗学

      The Menopause Transition and Epilepsy: A Focus on Therapeutics.

4300. 从诊断到治疗：患者对癌症照护的态度

      From diagnosis to treatment: patients' attitudes toward cancer care.

4301. PDGF刺激的角膜基质细胞在排列胶原纤维上的运动性和迁移模式被核心蛋白聚糖抑制

      PDGF-Stimulated Corneal Keratocyte Motility and Migration Patterns on Aligned Collagen Fibrils Are Inhibited by Decorin.

4302. 自闭症谱系障碍的早期检测方法：从临床筛查到多模态人工智能

      Early Detection Methods for Autism Spectrum Disorder: From Clinical Screening to Multimodal AI.

4303. 运动干预对轻度至中度脊柱侧凸青少年的影响：荟萃分析

      Effects of exercise interventions on adolescents with mild to moderate scoliosis: a meta-analysis.

4304. 仅骨寡转移性膀胱癌的立体定向体部放疗：一项多机构经验

      Stereotactic body radiotherapy for bone-only oligometastatic bladder Cancer: a multi-institutional experience.

4305. 头孢吡肟/恩美唑巴坦治疗肠杆菌目感染的真实世界结局：一项回顾性描述性研究

      Real-world outcomes of cefepime/enmetazobactam for Enterobacterales infections: a retrospective descriptive study.

4306. V-ATPase介导的管状胰高血糖素受体激活的肾脏保护作用

      Renoprotective effects of tubular glucagon receptor activation mediated by V-ATPase.

4307. NSUN2通过KLF4/GPX4轴抑制铁下垂，以保护干细胞和组织

      NSUN2 suppresses ferroptosis via the KLF4/GPX4 axis to preserve stem cells and tissues.

4308. 滤泡性淋巴瘤转化的特征是基质和巨噬细胞室的细胞因子相关重塑

      Follicular Lymphoma Transformation is Characterized by Cytokine-associated Remodeling of Stromal and Macrophage Compartments.

4309. 基于人工智能的颞下颌关节紊乱病和慢性口面部疼痛预后建模：一项关键的概念综述

      Artificial intelligence-based prognostic modeling in temporomandibular disorders and chronic orofacial pain: a critical conceptual review.

4310. 超越雄激素剥夺治疗：晚期前列腺癌的新一代激素治疗和新兴联合方案

      Beyond androgen deprivation therapy: Next-generation hormonal therapies and emerging combination approaches in advanced prostate cancer.

4311. 6PPD-醌破坏MARCHF2-EXOC7泛素轴，驱动足细胞铁死亡和氧化还原失衡

      6PPD-quinone disrupts the MARCHF2-EXOC7 ubiquitin axis to drive ferroptosis and redox imbalance in podocytes.

4312. 生物反馈治疗与盆底物理治疗在便秘和大便失禁治疗中的实际应用差异显著

      Biofeedback Therapy and Pelvic Floor Physical Therapy in the Treatment of Constipation and Fecal Incontinence Are Very Different in Real-World Practice.

4313. 补肺益肾方Ⅲ有效成分配伍治疗COPD的机制及枢纽基因鉴定

      Mechanism of effective-component compatibility of Bufei Yishen formula Ⅲ in COPD and identification of hub genes.

4314. 多激动剂中单独使用胰高血糖素受体信号传导和与胰高血糖蛋白样肽-1受体信号传导联合使用的心血管效应：一篇以翻译为重点的叙述性综述

      Cardiovascular Effects of Glucagon Receptor Signaling Alone and Combined With Glucagon-Like Peptide-1 Receptor Signaling in Multiagonists: A Narrative Review With a Translational Focus.

4315. [护士发展支持能力量表的信效度检验：繁体中文版（DSCSN-TC）]

      [The Reliability and Validity Examination of the Development Support Competency Scale for Nurses: Traditional Chinese Version (DSCSN-TC)].

4316. 可注射热敏性聚(2-乙基-2-噁唑啉)-聚(L-丙氨酸)水凝胶具有增强的力学性能和延长的体内持久性

      Injectable and thermosensitive poly(2-ethyl-2-oxazoline)-poly(L-alanine) hydrogel with enhanced mechanical performance and extended in vivo persistence.

4317. 妊娠期睡眠障碍与妊娠期高血压疾病之间的关联：队列研究的系统综述与荟萃分析

      Association between sleep disorders during pregnancy and hypertensive disorders of pregnancy: A systematic review and meta-analysis of cohort studies.

4318. 利用深度学习和全基因组测序在92种中枢神经系统相关疾病中探索药物重定位机会

      Drug repurposing opportunities across 92 CNS-related conditions using deep learning and whole-genome sequencing.

4319. 缺血性脑卒中老年人生活空间移动性的促进因素与障碍因素：基于COM-B的描述性定性研究

      Facilitators and barriers of life-space mobility in older adults with ischemic stroke: a descriptive qualitative study based on the COM-B.

4320. 通过表型驱动的罕见变异评估揭示46,XY性发育障碍中隐藏的遗传因素：一项初步研究

      Uncovering Hidden Genetic Contributors to 46,XY Disorders of Sex Development Through Phenotype-Driven Rare Variant Assessment: A Pilot Study.

4321. ASO实践指南系列：可切除结直肠癌

      ASO Practice Guidelines Series: Resectable Colorectal Cancer.

4322. 基于GnRH的免疫去势疫苗：比较分析及其在减少公猪膻味中的作用

      GnRH-Based Immunocastration Vaccines: Comparative Analysis and Role in Boar Taint Reduction.

4323. 泰吉利定与舒芬太尼患者自控静脉镇痛对老年腹腔镜结直肠癌手术患者胃肠功能恢复的影响：一项随机对照试验

      Tegileridine versus Sufentanil Patient-Controlled Intravenous Analgesia for Gastrointestinal Recovery in Elderly Patients Undergoing Laparoscopic Colorectal Cancer Surgery: A Randomized Controlled Trial.

4324. SIRT3抑制通过介导线粒体功能障碍和内皮-间充质转化促进与年龄相关的血管损伤

      SIRT3 inhibition promotes age-associated vascular impairment by mediating mitochondrial dysfunction and endothelial-to-mesenchymal transition.

4325. 肠道微生物群通过血浆代谢物对体格生长和认知表现的因果效应：一项孟德尔随机化研究

      Causal effects of gut microbiota on physical growth and cognitive performance via plasma metabolites: A Mendelian randomization study.

4326. 鸡传染性贫血病毒的完整基因组测序、进化动力学及致病性评估，以上埃及为重点，揭示与疫苗株相关的遗传变异性

      Full genome sequencing, evolutionary dynamics, and pathogenicity evaluation of chicken infectious anemia virus with emphasis on Upper Egypt reveals genetic variability linked to vaccinal strains.

4327. 基于人工智能的遗传性视网膜疾病诊断临床医生决策支持系统：一项多中心随机试验

      AI-based clinician decision support system for diagnosis of inherited retinal diseases: a multicenter, randomized trial.

4328. 急性COVID-19和长新冠综合征背后的IL-6家族细胞因子：机制、生物标志物和干预策略

      IL-6 family cytokines behind acute COVID-19 and Long COVID syndrome: Mechanisms, biomarkers, and intervention strategies.

4329. HUWE1通过RMC1靶向线粒体，促进神经发育

      HUWE1 targets mitochondria via RMC1 to promote neurodevelopment.

4330. 维持性血液透析患者中性粒细胞与淋巴细胞比值和C反应蛋白与白蛋白比值与肾性贫血的关系

      Association of Neutrophil-to-Lymphocyte Ratio and C-Reactive Protein-to-Albumin Ratio with Renal Anemia in Maintenance Hemodialysis Patients.

4331. 迈向青少年边缘型人格障碍的混合评估框架：关于人格功能、数字生物标志物和人工智能辅助评估的简要综述

      Toward a hybrid assessment framework for adolescent borderline personality disorder: a mini review of personality functioning, digital biomarkers, and AI-supported assessment.

4332. 职业使命感对护理实习生患者安全能力的影响：自主学习能力和临床思维能力的链式中介效应

      The impact of career calling on nursing interns' patient safety competency: a chained mediating effect of self-directed learning ability and clinical thinking ability.

4333. 通过琉球曲霉发酵和超声处理增强豆渣生物转化和蛋白质回收

      Enhanced okara bioconversion and protein recovery through Aspergillus luchuensis fermentation and ultrasound processing.

4334. 重新构想木质素增值：合成生物学赋能的可持续芳香碳生物制造

      Reimagining Lignin Valorization: Synthetic Biology-Enabled Sustainable Aromatic Carbon Biomanufacturing.

4335. 退变性腰椎侧凸伴椎管狭窄：Cobb角应如何指导减压与融合的决策？一项系统综述

      Degenerative lumbar scoliosis with stenosis: how should Cobb angle inform decompression versus fusion? A systematic review.

4336. 一锅法双交联明胶/海藻酸盐水凝胶用于3D打印肉类类似物的微观结构和质构调控

      One-pot dual-crosslinked gelatin/alginate hydrogels for microstructure and texture regulation in 3D-printed meat analogues.

4337. 脑损伤重新激活驱动瞬时LGE类中间神经元产生和整合的发育程序

      Brain injury reactivates a developmental program driving genesis and integration of transient LGE-class interneurons.

4338. 两例无CGG三核苷酸重复扩增的脆性X综合征新病例。临床-分子特征及文献综述

      Two new cases of fragile X syndrome without CGG triplet expansion. Clinical-molecular characterization and review of the literature.

4339. 病毒性肺炎血清脂质体重塑：从病理生理学到治疗学

      Serum lipidome remodeling in viral pneumonia: from pathophysiology to therapeutics.

4340. 裂解性多糖单加氧酶（LPMOs）：生物质多糖降解中的双刃剑

      Lytic polysaccharide monooxygenases (LPMOs): A double-edged sword in biomass polysaccharide degradation.

4341. 学校中面向青少年心理健康与福祉的自然项目范围综述

      A scoping review of nature-based programmes in schools for mental health and wellbeing in young people.

4342. 子宫内膜异位症与心血管疾病之间的关联：来自英国生物银行的见解

      Association Between Endometriosis and Cardiovascular Disease: Insights From the UK Biobank.

4343. 贝母辛通过抑制JAK/STAT通路减轻炎症和铁死亡，从而改善糖尿病肾病

      Peimisine ameliorates diabetic nephropathy by attenuating inflammation and ferroptosis through inhibition of the JAK/STAT pathway.

4344. 轻度至中度AECOPD合并和不合并肺气肿的临床和预后差异：一项为期3年的多中心前瞻性研究

      Clinical and prognostic differences in mild to moderate AECOPD with and without emphysema: a 3-year multicenter prospective study.

4345. 连续培养中合成基因电路的绝对定量表征

      Characterization of Synthetic Gene Circuits with Absolute Quantification in Continuous Culture.

4346. 心力衰竭的复杂性

      Heart failure through the lens of complexity.

4347. 药物对超重或肥胖成年人的比较效果：系统综述和网络荟萃分析

      Comparative effects of drugs for adults with overweight or obesity: systematic review and network meta-analysis.

4348. 识别病毒的塑料抗体：基于分子印迹聚合物的光学传感

      Plastic antibodies that see viruses: optical sensing with molecularly imprinted polymers.

4349. 聚苯乙烯纳米塑料的肠肝循环通过损伤肠神经元促进肠道炎症

      Enterohepatic Circulation of Polystyrene Nanoplastics Promotes Intestinal Inflammation by Impairing Enteric Neurons.

4350. 基于新型影像表型的慢阻肺精准治疗：可治疗特征方法

      Precision treatment of COPD based on novel imaging phenotypes: a treatable traits approach.

4351. 动脉粥样硬化和血管钙化的区域异质性

      Territorial heterogeneity of atherosclerosis and vascular calcification.

4352. 整合黏弹性成像与微血管超声的多参数超声检查用于慢性肾病的诊断与分期

      Multiparametric Ultrasonography Integrating Viscoelastic Imaging and Microvascular Ultrasound for Diagnosis and Staging of Chronic Kidney Disease.

4353. 双胰高血糖素样肽-1和胰高血糖蛋白受体激动剂马兹度肽对肥胖和/或2型糖尿病主要中国成年人的疗效和安全性：系统评价和荟萃分析

      Efficacy and Safety of the Dual Glucagon-Like Peptide-1 and Glucagon Receptor Agonist Mazdutide in Predominantly Chinese Adults With Obesity and/or Type 2 Diabetes: A Systematic Review and Meta-Analysis.

4354. 冠内屏障位置对漂白效果和过氧化物扩散的影响

      Effect of Intracoronal Barrier Location on Bleaching Efficacy and Peroxide Diffusion.

4355. 黄芪和丹参注射液通过SERCA/SIRT1介导的Ca2+调节提供心脏保护

      {"_":"Astragalus membranaceus and Salvia miltiorrhiza injections confer cardioprotection via SERCA/SIRT1-mediated Ca regulation.","sup":["2+"]}

4356. 妇科癌症的前哨淋巴结活检。

      Sentinel Lymph Node Biopsy for Gynecologic Cancers.

4357. 抗GnRH疫苗Improvac对成年母猫（Felis catus）发情活动及卵巢和子宫形态的影响

      Effects of an Anti-GnRH Vaccine Improvac on Estrous Activity, and Ovarian and Uterine Morphology in Adult Queens (Felis catus).

4358. 整合单细胞和空间转录组学揭示间质性膀胱炎/膀胱疼痛综合征患者的基质-免疫-血管串扰

      Integrated single-cell and spatial transcriptomics reveal stromal-immune-vascular crosstalk in patients with interstitial cystitis/bladder pain syndrome.

4359. PNPLA3 I148M变异体通过iPSC衍生模型中的AMIGO2上调激活肝星状细胞

      PNPLA3 I148M Variant Activates Hepatic Stellate Cells via AMIGO2 Upregulation Using iPSC-Derived Model.

4360. 来源于c-Cbl相关蛋白的内源性肽可拮抗其对先天性巨结肠症中肠神经嵴细胞定植的抑制作用

      Endogenous Peptide Derived from c-Cbl-Associated Protein Counteracts Its Inhibitory Effect on Enteric Neural Crest Cell Colonization in Hirschsprung Disease.

4361. 长链非编码RNA介导前列腺癌中的内分泌信号传导和耐药性

      Long noncoding RNAs mediate endocrine signaling and resistance in prostate cancer.

4362. 使用常规12导联心电图机器学习对“运动员心脏”进行分类：CHIEF研究中男性精英3000米跑者数据

      Classification of "Athlete's Heart" using machine learning of conventional 12-lead ECG: male elite 3,000-m runner data in the CHIEF study.

4363. 设计和映射级联催化路径以实现Li-S电池中多硫化物的平衡转化

      Designing and mapping cascade catalysis pathway for balanced polysulfide conversion in Li-S batteries.

4364. 铗蠓属（毛蠓亚属）蠓类的整合形态学与DNA条形码分析：泰国南部一个利什曼病流行疫点中的隐存多样性及多种利什曼原虫的首次分子检测

      Integrative morphological and DNA barcoding analysis of Forcipomyia (Lasiohelea) midges: cryptic diversity and first molecular detection of multiple Leishmania species in a leishmaniasis-endemic focus in Southern Thailand.

4365. 早期与延迟启动双联抗菌挽救治疗对MRSA菌血症临床结局的影响

      Impact of early vs delayed initiation of dual antimicrobial salvage therapy on clinical outcomes in MRSA bacteremia.

4366. 伊朗不孕症治疗体验：定性证据的系统评价与Meta综合研究方案

      Infertility treatment experiences in Iran: protocol for a systematic review and meta-synthesis of qualitative evidence.

4367. 利用转录组学分析鉴定乳腺癌中的枢纽基因、单核苷酸多态性及潜在药物靶点

      Identification of Hub Genes, Single-Nucleotide Polymorphisms, and Potential Drug Targets In Breast Cancer Using Transcriptomic Analysis.

4368. 从修复到再生：数字牙科3D打印策略综述

      From Restoration to Regeneration: A Review of 3D Printing Strategies in Digital Dentistry.

4369. DAPK3-DCAF1通路调节ZBP1蛋白的稳定性，以协调卵巢癌症治疗的泛光症

      The DAPK3-DCAF1 pathway regulates ZBP1 protein stability to orchestrate PANoptosis for ovarian cancer therapy.

4370. 使用fNIRS探索功能性便秘患者的脑活动差异：一项病例对照研究

      Exploring brain activity differences in functional constipation using fNIRS: a case-control study.

4371. lncRNA LINC00052通过海绵状miR-106b-5p减轻败血症相关的急性肺损伤

      Attenuation of sepsis-associated acute lung injury by lncRNA LINC00052 via sponging miR-106b-5p.

4372. 中国孕妇身体形象现状及影响因素研究：混合方法研究

      A study on current status and influencing factors of pregnant women's body image in China: A mixed-methods study.

4373. 与米氮平治疗重度抑郁症反应相关的神经病理生理变化：自下而上多巴胺能通路和前额叶控制网络的见解

      Neuropathophysiological changes associated with mirtazapine treatment response in major depressive disorder: insights into bottom-up dopaminergic pathways and prefrontal control networks.

4374. 穆勒棘轮作用下的通才进化

      Evolution of generalism under Muller's ratchet.

4375. 尿路上皮癌的组织亚型和分化：组织学、基因组学和管理意义

      Histological Subtypes and Divergent Differentiation of Urothelial Carcinoma: Histology, Genomics, and Management Implications.

4376. 超越LUMIR挑战：通往基础注册模型的路径

      Beyond the LUMIR challenge: The pathway to foundational registration models.

4377. 电沉积磷酸钙涂层对骨植入物早期炎症反应的免疫调节作用

      Immunomodulatory effect of electrodeposited calcium phosphate coatings on early inflammatory response to bone implant.

4378. 光学相干断层扫描量化的视网膜特征与心血管-肾脏-代谢综合征0-3期心血管风险之间的关联：一项前瞻性英国生物银行队列分析

      Association between optical coherence tomography-quantified retinal features and cardiovascular risk in cardiovascular-kidney-metabolic syndrome stages 0-3: An analysis of a prospective UK biobank cohort.

4379. DMEK、DSAEK和重复PKP治疗PKP后内皮衰竭：系统综述和荟萃分析，结合临床决策因素的图形综合

      DMEK, DSAEK, and repeat PKP for endothelial failure after PKP: systematic review and meta-analysis with a graphical synthesis of clinical decision factors.

4380. [抗抑郁药的临床应用：个体药物的优势和机会]

      [Clinical application of antidepressants: Advantages and opportunities for individual drugs].

4381. 结核分枝杆菌外泌体和金属耐药性的演变

      {"_":"Effluxosomes and the evolution of metal resistance in .","i":["Mycobacterium tuberculosis"]}

4382. 泌尿生殖系统肿瘤学中的人工智能：发表趋势和系统综述

      Artificial intelligence in genitourinary oncology: publication trends and systematic review.

4383. 从肠道微生态学角度看与免疫检查点抑制剂相关的心血管不良事件：肠道微生物群的潜在作用和研究进展

      Cardiovascular Adverse Events Associated with Immune Checkpoint Inhibitors from the Perspective of Gut Microecology: Potential Roles and Research Advances of the Gut Microbiota.

4384. 髂内动脉修复和增强保护（ELFIRE）手术的耐久性肢体开窗术的中期结果

      Midterm Outcomes of the Endurant Limb Fenestration With Internal Iliac Artery Repair and Enhanced Preservation (ELFIRE) Procedure.

4385. 药学技术人员在医院病房中的作用和影响：系统综述

      Roles and impact of pharmacy technicians on hospital wards: a systematic review.

4386. 病例报告：接受局部化疗的DLBCL玻璃体视网膜淋巴瘤局部免疫调节介质的纵向分析

      Case Report: Longitudinal analysis of local immunoregulatory mediators in a DLBCL vitreoretinal lymphoma receiving local chemotherapy.

4387. 解读消化系统肿瘤中的肿瘤内微生物群：机制和新的治疗策略

      Deciphering intratumoral microbiota in digestive system tumors: mechanisms and emerging therapeutic strategies.

4388. 从尿酸到痛风石：痛风石形成的多阶段分子和细胞机制

      From uric acid to tophi: multistage molecular and cellular mechanisms of tophi formation.

4389. 肝细胞癌中的免疫代谢重编程：机制、生物标志物与治疗意义

      Immunometabolic Reprogramming in Hepatocellular Carcinoma Mechanisms, Biomarkers, and Therapeutic Implications.

4390. 探索银屑病和银屑病性关节炎中肠道微生物组的关联：范围综述

      Exploring the Gut Microbiome's Association in Psoriasis and Psoriatic Arthritis: A Scoping Review.

4391. 临床肿瘤学中的生成性人工智能和大型语言模型

      Generative Artificial Intelligence and Large Language Models in Clinical Oncology.

4392. 新生儿和儿童氨基糖苷类引起的听力损失的机制、预防和管理：翻译综述

      Mechanisms, prevention, and management of aminoglycoside-induced hearing loss in neonates and children: a translational review.

4393. 罗沙度他汀治疗慢性肾病贫血的血栓形成结果和死亡率：随机试验的系统评价和荟萃分析

      Thrombotic outcomes and mortality with roxadustat for anemia in chronic kidney disease: a systematic review and meta-analysis of randomized trials.

4394. 对有自杀意念的重度抑郁症患者肠道微生物群改变的新见解：宏基因组分析

      Novel insights into gut microbiota alterations in major depressive disorder with suicidal ideation: a metagenomic analysis.

4395. 放线菌在水产养殖中的双重作用：代谢益处和有害影响的系统综述

      The dual role of Actinobacteria in aquaculture: a systematic review of metabolic benefits and detrimental effects.

4396. 白桦脂酸通过调节TLR4/MyD88/NF-κB信号轴和NLRP3炎症小体通路减轻小鼠感染性心肌病

      Betulinic acid mitigates septic cardiomyopathy in mice through modulating the TLR4/MyD88/NF-κB signaling axis and NLRP3 inflammasome pathway.

4397. 肺纤维化中的内皮细胞视角：从细胞命运决定、细胞间通讯和EndoMT到新兴疗法

      The Endothelial Cell Perspective in Pulmonary Fibrosis: From Cell Fate Decisions, Intercellular Communication, and EndoMT to Emerging Therapies.

4398. 考虑给药时间的盐酸伊立替康给药可减轻大鼠延迟性腹泻

      Irinotecan Hydrochloride Administration Considering Dosing-Time Attenuates Delayed Diarrhea in Rats.

4399. 使用表面分子印迹聚合物修饰的丝网印刷电极对铜绿假单胞菌进行超灵敏无标记电化学检测

      {"_":"Ultrasensitive Label-Free Electrochemical Detection of Using a Surface Molecularly Imprinted Polymer-Modified Screen-Printed Electrode.","i":["Pseudomonas aeruginosa"]}

4400. 罗哌卡因-地塞米松给药后唾液皮质醇反应：一项随机临床试验

      Salivary Cortisol Response After Ropivacaine-Dexamethasone Administration: A Randomized Clinical Trial.

4401. 多组分制剂的有效性：胃食管反流症状患者的前瞻性观察研究

      Effectiveness of a Multicomponent Formulation: A Prospective Observational Study in Patients with Gastroesophageal Reflux Symptoms.

4402. 抗变色系统（ADS）对碱硅酸盐和复合树脂光学稳定性的影响：氯己定与咖啡协同染色效应的比较研究

      Impact of Anti-Discoloration System (ADS) on the Optical Stability of Alkasite and Composite Resins: A Comparative Study on the Synergistic Staining Effect of Chlorhexidine and Coffee.

4403. 与TALD病例相关的酒店供水系统嗜肺军团菌的混合职业风险评估

      {"_":"A Hybrid Occupational Risk Assessment of in Hotel Water Systems Associated with TALD Cases.","i":["Legionella pneumophila"]}

4404. 以患者为中心的沟通和行为指导：牙科实践中培训师-医生模式的探索性评估

      Patient-Centred Communication and Behavioural Guidance: An Exploratory Evaluation of the Trainer-Doctor Model in Dental Practice.

4405. 2岁以下IgE介导的鸡蛋过敏儿童早期口服巴氏消毒蛋清免疫治疗：一项具有历史对照的前瞻性研究

      Early Oral Immunotherapy with Pasteurized Egg White in Children Younger than Two Years with IgE-Mediated Egg Allergy: A Prospective Study with Historical Controls.

4406. 活化的巨噬细胞通过PIEZ01-NFATC2/REL轴促进垂体卒中中TNF-α相关肿瘤细胞坏死

      Activated Macrophages Promote TNF-α-Associated Tumor Cell Necroptosis in Pituitary Apoplexy Through the PIEZO1-NFATC2/REL Axis.

4407. {“_”：“心房颤动的系统性分子改变和miR-34a表达：一项前瞻性探索性生物标志物研究”，“i”：[“TP53”，“SIRT-1”]}

      {"_":"Systemic Molecular Alterations of , , and miR-34a Expression in Atrial Fibrillation: A Prospective Exploratory Biomarker Study.","i":["TP53","SIRT-1"]}

4408. 激素受体阳性、HER2阴性转移性癌症中-CDK4/6后抑制剂的治疗方法：当前证据和新策略——叙述性综述

      Post-CDK4/6 Inhibitor Therapeutic Approaches in Hormone Receptor-Positive, HER2-Negative Metastatic Breast Cancer: Current Evidence and Emerging Strategies-A Narrative Review.

4409. 中国队列中SARS-CoV-2 IgM、IgG和中和抗体的表达水平，以及新冠肺炎患者的肽特异性抗体检测

      Expression levels of SARS-CoV-2 IgM, IgG, and neutralizing antibodies in a Chinese cohort and detection of peptide-specific antibodies in COVID-19 patients.

4410. 脑脊液和血浆pTau-181、pTau-217和pTau-231对阿尔茨海默病的诊断准确性：诊断荟萃分析

      Diagnostic accuracy of CSF and plasma pTau-181, pTau-217, and pTau-231 for Alzheimer's disease: a diagnostic meta-analysis.

4411. 腺苷受体信号传导在血管疾病中的作用：从分子机制到靶向治疗

      Adenosine receptor signaling in vascular diseases: from molecular mechanisms to targeted therapeutics.

4412. EdgeFusionNet：通过边缘云协作架构上的轻量级跨模式注意力融合，为乒乓球训练提供实时多模式反馈

      EdgeFusionNet: real-time multimodal feedback for table tennis training via lightweight cross-modal attention fusion on edge-cloud collaborative architecture.

4413. [人工智能驱动的癌症三级淋巴结构评估：从显微镜分析到临床转化]

      [Artificial intelligence-driven assessment of tertiary lymphoid structures in breast cancer: From microscopic analysis to clinical translation].

4414. [HLA-B27改变肠道微生物组成并促进肠道炎症易感性]

      [HLA-B27 alters gut microbial composition and promotes susceptibility to intestinal inflammation].

4415. PVCA分类在指导颈部血管损伤管理策略方面的有效性

      Efficacy of PVCA classification in guiding management strategies for cervical vascular trauma.

4416. 靶向NEK9通过重塑免疫抑制微环境与肝细胞癌的免疫治疗协同作用

      Targeting NEK9 synergises with immunotherapy in hepatocellular carcinoma by remodelling the immunosuppressive microenvironment.

4417. FLT3L分泌cDC1的原位免疫增强小鼠非小细胞肺癌的抗肿瘤免疫，并与PD-1阻断协同作用

      FLT3L-secreting cDC1 in situ vaccination enhances antitumor immunity and synergizes with PD-1 blockade in murine non-small cell lung cancer.

4418. 开发和验证可解释的机器学习模型，用于预测原发性腹膜炎危重患者的急性肾损伤：一项多中心队列研究

      Development and validation of an explainable machine learning model for predicting acute kidney injury in critically ill patients with primary peritonitis: a multicenter cohort study.

4419. 减轻新生儿重症监护室医护人员的道德痛苦：试点项目

      Mitigating Moral Distress in Neonatal Intensive Care Unit Healthcare Professionals: A Pilot Program.

4420. 正畸矫治器拆除期间的情绪状态与疼痛体验：四种去粘接方案的评估

      Emotional State and Pain Experience During Orthodontic Appliance Removal: Evaluation of Four Debonding Protocols.

4421. 将机器学习技术集成到基于心电图的多类心律失常分类和可解释性分析中

      Integration of Machine Learning Techniques in ECG-Based Multiclass Arrhythmia Classification with Explainability Analysis.

4422. 分子印迹方法在电化学蛋白质生物传感器开发中的进展与展望

      Progress and Perspectives of Molecular Imprinting Methods in the Development of Electrochemical Protein Biosensors.

4423. 增强酿酒酵母单细胞蛋白生产的代谢与合成生物学策略

      Metabolic and Synthetic Biology Strategies for Enhancing Single-Cell Protein Production in Saccharomyces cerevisiae.

4424. 经济毒性：不平等及其对心血管疾病的影响

      Financial Toxicity: Inequities and Impact on Cardiovascular Disease.

4425. 嗜铬细胞瘤引起的异位ACTH综合征：两例患者的诊断挑战与手术结局

      Ectopic ACTH syndrome caused by pheochromocytoma: diagnostic challenges and surgical outcomes in two cases.

4426. 青蒿素相关自身免疫性甲状腺炎治疗策略：趋化因子-受体网络、甲状腺空间生物学及分子机制

      Artemisinin-Related Therapeutic Strategies for Autoimmune Thyroiditis: Chemokine-Receptor Networks, Spatial Thyroid Biology, and Molecular Mechanisms.

4427. 左心室肥厚的诊断方法：综述

      Diagnostic Approach to Left Ventricular Hypertrophy: A Review.

4428. 皮层灰白质对比度改变先于无痴呆老年人的淀粉样蛋白-β阳性和宏观结构变化

      Cortical gray-white matter contrast alterations precede amyloid-β positivity and macrostructural changes in older adults without dementia.

4429. 伊朗西部蜱和小反刍动物中的克里米亚-刚果出血热病毒：流行病学见解和基因分型

      Crimean-congo haemorrhagic fever virus in ticks and small ruminants in western Iran: epidemiological insights and genotyping.

4430. 在ALS中，与运动神经元状态相关的紧急疾病先于细胞死亡

      An emergent disease-associated motor neuron state precedes cell death in ALS.

4431. 1，021例儿童胰腺肿瘤的系统综述和汇总分析

      Systematic Review and Pooled Analysis of 1,021 Children With Pancreatic Tumors.

4432. 法国男性尿路感染的细菌流行病学：专家综述

      Bacterial epidemiology of male urinary tract infections in France: An expert review.

4433. 一例伴有瘤颈动脉粥样硬化、模拟梭形动脉瘤的大脑中动脉分叉部宽颈囊状动脉瘤：示例病例

      A wide-necked saccular aneurysm of the middle cerebral artery bifurcation with neck atherosclerosis mimicking a fusiform aneurysm: illustrative case.

4434. 护理专业学生对老年人的态度：系统综述和荟萃分析

      Attitudes of nursing students toward older adults: a systematic review and meta-analysis.

4435. 普通人群血浆动脉粥样硬化指数与主动脉瓣钙化的相关性：一项回顾性观察队列研究

      The correlation between the atherogenic index of plasma and aortic valve calcification in the general population: a retrospective observational cohort study.

4436. 新西兰Aotearoa地区Wolfram综合征与糖尿病：表型及对GLP-1受体激动剂治疗的反应

      Wolfram syndrome and diabetes mellitus in Aotearoa, New Zealand: Phenotype and response to GLP-1 receptor agonist therapy.

4437. 一株引起免疫鸭群暴发的强毒鸭肠炎病毒的分离、鉴定及致病性分析

      Isolation, identification and pathogenicity analysis of a virulent duck enteritis virus strain causing outbreak in vaccinated duck flocks.

4438. 白藜芦醇通过抑制AKT/mTOR信号通路减轻神经源性膀胱纤维化和尿路上皮细胞焦亡

      Resveratrol Alleviates Neurogenic Bladder Fibrosis and Urothelial Pyroptosis by Inhibiting the AKT/mTOR Signaling Pathway.

4439. 岛叶及岛盖-岛叶癫痫发作起源的运动过度性发作：一项系统性综述

      Hyperkinetic Seizures in Insular and Insulo-Opercular Seizure Onset: A Systematic Review.

4440. 大学生体力活动与自我控制的关系：特质焦虑的中介作用

      The relationship between physical activity and self-control in college students: the mediating role of trait anxiety.

4441. 基于分子印迹的伪酶联免疫吸附测定：最新进展

      Molecular imprinting-based pseudo-ELISA: recent advances.

4442. 慢性瘙痒的脊髓与脊髓上机制：从神经回路到神经-免疫-微生物轴

      Spinal and supraspinal mechanisms of chronic itch: from neuronal circuits to the neuro-immune-microbial axis.

4443. 瓦伯格效应提供了有助于肿瘤细胞抵抗的特性

      The Warburg effect provides attributes that facilitate tumor-cell resistance.

4444. 线粒体基因快速丢失对细胞器蛋白质组的影响

      The Effects of Rapid Mitochondrial Gene Loss on Organellar Proteomes.

4445. 80岁及以上人群中失眠的患病率及相关因素：一项横断面研究

      Prevalence of insomnia and related factors in individuals aged 80 years and over: a cross-sectional study.

4446. 优化免疫检查点抑制剂诱导的炎性关节炎的管理：病例系列和文献综述

      Optimizing management of immune checkpoint inhibitor-induced inflammatory arthritis: A case series and literature review.

4447. 针对年龄相关性听力损失老年人的基于网络的游戏化听觉-认知双任务训练：一项试点随机对照试验

      Web-Based Gamified Auditory-Cognitive Dual-Task Training for Older Adults With Age-Related Hearing Loss: Pilot Randomized Controlled Trial.

4448. 黄芪对子痫前期大鼠炎症和细胞凋亡的影响

      The effects of Astragalus membranaceus on inflammation and apoptosis in rats with preeclampisa.

4449. 细胞衰老的血浆蛋白质组学特征预测人类疾病

      Plasma proteomic signatures of cellular aging predict human disease.

4450. 精准医学不可避免地向罕见病规模队列发展的轨迹：对机器学习和深度学习的影响

      Precision medicine's inevitable trajectory toward rare-disease-sized cohorts: implications for machine learning and deep learning.

4451. 护理实习生潜在的伦理敏感性和相关因素

      Latent profiles of ethical sensitivity and correlates in nursing interns.

4452. 来自泰国发酵大豆（Thua-nao）的染料木素通过双重抑制NF-κB和MAPK信号通路减轻骨关节炎发病机制：来自离体、计算和体外模型的证据

      Genistein from Thai Fermented Soybean (Thua-nao) Attenuates Osteoarthritis Pathogenesis via Dual Inhibition of NF-κB and MAPK Signaling: Evidence from Ex Vivo, Computational, and In Vitro Models.

4453. 综合音乐和职业治疗对神经源性脊柱侧凸儿童运动和自主神经功能的影响

      Effects of Integrated Music and Occupational Therapy on Motor and Autonomic Function in Children with Neurogenic Scoliosis.

4454. 豌豆蛋白强化发酵杏仁饮料对百草枯诱导氧化应激的增强保护潜力

      Enhanced Protective Potential of a Pea Protein-Fortified Fermented Almond Beverage Against Paraquat-Induced Oxidative Stress.

4455. 靶向乙酰肝素酶介导的糖萼降解作为抑制EMT驱动肺纤维化的新策略

      Targeting heparanase-mediated glycocalyx degradation as a novel strategy to inhibit EMT-driven pulmonary fibrosis.

4456. 运动诱发性致心律失常性心肌病的重新分类：在一名男性运动员中检测到致病性PKP2变异

      Reclassification of Exercise-Induced Arrhythmogenic Cardiomyopathy: Detection of a Pathogenic PKP2 Variant in a Male Athlete.

4457. {"_":"整合多组学分析揭示宫颈阴道生态网络及其与载量的关联。","i":["沙眼衣原体"]}

      {"_":"Integrated multi-omics analysis uncovers cervicovaginal ecological networks and their association with load.","i":["Chlamydia trachomatis"]}

4458. 蒸汽爆破灵芝多糖的酶辅助提取及其得率、结构表征与免疫调节活性

      {"_":"Enzyme-Assisted Extraction of Polysaccharides from Steam-Exploded and Its Yield, Structural Characterisation, and Immunomodulatory Activity.","i":["Ganoderma lucidum"]}

4459. 一种具有触发收缩和持续抗菌释放的形状记忆水凝胶用于急性感染伤口愈合

      A shape-memory hydrogel with triggered contraction and sustained antibacterial release for acute infected wound healing.

4460. 特发性肺纤维化中焦虑和抑郁的患病率：系统评价与荟萃分析

      Prevalence of anxiety and depression in idiopathic pulmonary fibrosis: a systematic review and meta-analysis.

4461. 白杨素通过抑制NOX2依赖性铁死亡和STING/NLRP3介导的炎症反应减轻干眼进展

      Chrysin Attenuates Dry Eye Progression by Suppressing NOX2-Dependent Ferroptosis and STING/NLRP3-Mediated Inflammatory Responses.

4462. 喹唑啉通过增强神经干细胞的增殖和分化减轻内耳损伤

      Quinazoline alleviates inner ear damage by enhancing the proliferation and differentiation of neural stem cells.

4463. 艾司氯胺酮加速腹腔镜妇科手术患者丙泊酚麻醉苏醒：一项随机对照试验

      Esketamine Accelerates Emergence from Propofol Anesthesia in Patients Undergoing Laparoscopic Gynecological Surgery: A Randomized Controlled Trial.

4464. 二极管激光治疗复发性阿弗他口炎和口腔扁平苔藓的疗效：一项系统综述

      Efficacy of Diode Laser Therapy in Managing Recurrent Aphthous Stomatitis and Oral Lichen Planus: A Systematic Review.

4465. OrgLine：一种利用检测器引导提示的通用类器官形态测量流程

      OrgLine: A versatile pipeline for organoid morphometry using detector-guided prompts.

4466. 在肿瘤微环境中提供抗原和共刺激的mRNA LNP疫苗增强CAR-T细胞功能（CART-Vac）

      mRNA-LNP vaccine providing antigen and co-stimulation in the tumor microenvironment enhances CAR T cell function (CART-Vac).

4467. 硫醇化壳聚糖-硬脂酸硫醇连接仿生水凝胶用于轴突再生和神经组织再生

      Thiolated Chitosan-Stearic Acid Thiol-Linked Biomimetic Hydrogels for Axonal Regrowth and Neuronal Tissue Regeneration.

4468. 爱泼斯坦-巴尔病毒疫苗的进展

      Progress toward an Epstein-Barr virus vaccine.

4469. 9mg马兹度肽治疗中国肥胖成年人的减肥：GLORY-2随机临床试验

      Treatment With 9-mg Mazdutide for Weight Reduction in Chinese Adults With Obesity: The GLORY-2 Randomized Clinical Trial.

4470. 脑梗死对认知和言语能力的影响

      Effects of cerebral infarction on cognitive and speech performance.

4471. ALKBH5通过m6A RNA甲基化调节FOXA1表达，促进顺铂耐药口腔鳞状细胞癌的进展：资助

      {"_":"ALKBH5 promotes the progression of cisplatin-resistant oral squamous cell carcinoma by regulating FOXA1 expression via mA RNA methylation : Funding.","sup":["6"]}

4472. 炎症相关临床体征在检测干眼病中MMP-9表达的诊断效用：一项横断面结膜印迹细胞学和微滴数字PCR研究。

      Diagnostic utility of inflammation-associated clinical signs in detecting MMP-9 expression in dry eye disease: A cross-sectional conjunctival impression cytology and droplet digital PCR study.

4473. 大型语言模型在泌尿外科决策支持中的表现：一项基于指南的尿石症比较评价

      Performance of large language models in urological decision support: a guideline-based comparative evaluation in urolithiasis.

4474. 靶向DMPK的反义介导基因治疗恢复1型强直性肌营养不良的心脏离子通道功能和电稳定性

      Antisense-mediated gene therapy targeting DMPK restores cardiac ion channel function and electrical stability in myotonic dystrophy type 1.

4475. 妊娠期及产后乳腺癌的临床和病理特征及预后：一项多中心回顾性研究

      Clinical and Pathological Characteristics and Prognosis of Breast Cancer During Pregnancy and Postpartum: A Multicenter Retrospective Study.

4476. {"_":"鱼鳞状P掺杂碳纳米片/NiSe-CoSe异质结中间层实现协同催化与限域用于高性能锂硫电池隔膜。","sub":["2","2"]}

      {"_":"A Fish-Scale-like P-Doped Carbon Nanosheet/NiSe-CoSe Heterojunction Interlayer Enabling Synergistic Catalysis and Confinement for High-Performance Li-S Battery Separators.","sub":["2","2"]}

4477. ATAD3A通过线粒体溶酶体接触和脂酰化限制主动脉夹层

      ATAD3A Limits Aortic Dissection via Mito-Lysosome Contacts and Lipoylation.

4478. 股骨头早期骨坏死的放松时间图：一项活体仔猪模型研究

      Relaxation Time Mapping of Early-Stage Osteonecrosis of the Femoral Head: An In Vivo Piglet Model Study.

4479. 前列腺癌症：分期、进展和治疗

      Prostate Cancer: Staging, Progression, and Treatment.

4480. 人脐血干细胞疗法、手术和再生康复对慢性脊髓损伤的多模式治疗：临床综述

      Multimodal Treatment of Chronic Spinal Cord Injury With Human Cord Blood Stem Cell Therapy, Surgery, and Regenerative Rehabilitation: Clinical Review.

4481. 烟酰胺核糖通过促进记忆分化和代谢适应性增强过继性T细胞治疗

      Nicotinamide riboside enhances adoptive T cell therapy by promoting memory differentiation and metabolic fitness.

4482. 黑果越橘（Vaccinium myrtillus L.）水溶性花青素通过靶向ALOX15介导的脂质过氧化 alleviates 糖尿病肾病

      Water-soluble anthocyanins from Vaccinium myrtillus L. alleviate diabetic kidney disease by targeting ALOX15-mediated lipid peroxidation.

4483. 调查重症监护护士道德困扰与述情障碍水平之间的关系：一项描述性和相关性研究

      Investigating the Relationship Between Moral Distress and Alexithymia Levels Among Intensive Care Nurses: A Descriptive and Correlational Study.

4484. 植物代谢产物和中药配方在胃癌前病变和癌症中调节糖酵解-OXPHOS可塑性的潜在作用：证据的关键评估

      Potential roles of plant metabolites and Traditional Chinese Medicine formulas in regulating glycolysis-OXPHOS plasticity in gastric precancerous lesions and gastric cancer: a critical appraisal of the evidence.

4485. 血小板调控驱动皮肤炎症和瘙痒的神经免疫轴

      Platelets Orchestrate a Neuroimmune Axis Driving Cutaneous Inflammation and Itch.

4486. 731种免疫细胞与膀胱炎之间的因果关联分析：一项双样本双向孟德尔随机化研究

      Causal association analysis between 731 immune cells and cystitis: A 2-sample, bidirectional Mendelian randomization study.

4487. 尺骨鹰嘴骨巨细胞瘤伴移位病理性骨折经病灶内刮除及钢板固定成功治疗：一例报告

      Giant Cell Tumor of the Olecranon With a Displaced Pathological Fracture Successfully Treated by Intralesional Curettage and Plate Fixation: A Case Report.

4488. 用鼠李糖乳酪杆菌发酵的异质琼胶和含石莼聚糖海藻的功能和营养谱变化

      Changes in the functional and nutritional profiles of heterogeneous agarans and ulvan-bearing seaweeds fermented with Lacticaseibacillus rhamnosus.

4489. NLRP3炎症抑制通过抑制铁下垂减轻糖尿病肾损伤：体内和体外模型的机制见解

      NLRP3 Inflammasome Inhibition Attenuates Diabetic Kidney Injury via the Suppression of Ferroptosis: Mechanistic Insights from In Vivo and In Vitro Models.

4490. 评估组织光学灌注压方法在伴和不伴动脉中层钙化的糖尿病患者中的应用

      Evaluating the Tissue Optical Perfusion Pressure Method in Diabetic Patients with and Without Media Arterial Calcification.

4491. 慢性鼻窦炎中情绪负担的性别差异…… (原文已截断)

      Gender Differences in Emotional Burden in Chronic Rhinosinusitis: The Role of Sleep-Related Impairment.

4492. 细菌性菌群失调在不孕不育中的作用：BIOME研究方案——一项丹麦多中心前瞻性观察性队列研究

      Role of bacterial dysbiosis in infertility: the BIOME study protocol for a Danish multicentre prospective observational cohort study.

4493. 细胞死亡相关标志物的差异表达可能反映了渗出性和非渗出性猫感染性腹膜炎中不同的肾脏损伤模式

      Differential expression of cell death-associated markers may reflect distinct renal lesion patterns in effusive and non-effusive feline infectious peritonitis.

4494. 探索混合现实技术在机器人辅助腹腔镜肾上腺部分切除术中的优势

      Exploring the advantages of mixed reality technology in Robot-assisted laparoscopic partial adrenalectomy.

4495. 一线的阿曲南：一种治疗金属β-内酰胺酶耐药性的双药途径

      Aztreonam-avibactam at the frontline: A dual-agent approach to metallo-β-lactamase resistance.

4496. 关于PSVD或NCPF新通用定义和诊断标准的多学会共识声明

      A multisociety consensus statement on a new common definition and diagnostic criteria for PSVD or NCPF.

4497. 基于生物电阻抗分析的肌少症性肥胖表型指数与肌少症性肥胖：与社区老年人衰弱、跌倒和骨质疏松症的关联

      Bioelectrical impedance analysis-based Sarcopenic Obesity Phenotype Index versus sarcopenic obesity: associations with frailty, falls, and osteoporosis in community-dwelling older adults.

4498. {"_":"系统重编程球形红细菌以高效生物合成辅酶Q10和卟啉。","i":["Rhodobacter sphaeroides"]}

      {"_":"Systematic Reprogramming of for Efficient Biosynthesis of Coenzyme Q10 and Porphyrins.","i":["Rhodobacter sphaeroides"]}

4499. 蟾蜍灵转录后抑制STAT3，以缓解糖尿病肾病中的肾铁凋亡和肾小管间质纤维化

      Bufalin post-transcriptionally suppresses STAT3 to alleviate renal ferroptosis and tubulointerstitial fibrosis in diabetic kidney disease.

4500. 红光和蓝光对话调控气孔以实现节水作物

      The red and blue light dialog of stomatal regulation for water-efficient crops.

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