乌干达西南部一所三级教学医院的少女怀孕合并症
Comorbidities of Adolescent Pregnancy at a Tertiary Teaching Hospital in Southwestern Uganda.
Comorbidities of Adolescent Pregnancy at a Tertiary Teaching Hospital in Southwestern Uganda.
背景 青少年妊娠在全球范围内带来重大健康挑战。每年,发展中地区有数百万少女怀孕。在乌干达,青少年妊娠仍然常见,且存在明显的地区差异。社会经济状况低下、受教育程度有限或面临避孕措施获取障碍的青少年更容易发生非意愿妊娠。这些妊娠可能导致多种健康并发症,包括早产、小于胎龄儿、产后抑郁、贫血和尿路感染(UTIs)。方法 2024年7月至9月在乌干达姆巴拉拉市姆巴拉拉区域转诊医院三级机构开展了一项横断面研究,纳入前来产前保健(ANC)就诊或分娩的青少年孕妇。数据收集包括临床检查(血压和上臂中围(MUAC))和实验室检测(血红蛋白、HIV、乙型肝炎、随机血糖和尿液分析)。通过结构化问卷收集社会人口学和产科特征数据。数据使用STATA版本17(StataCorp LLC,College Station,TX,USA)进行分析,合并症依据临床标准定义,如高血压、贫血、HIV感染、子痫前期、高血糖和UTIs。结果 共纳入252名参与者。中位年龄为18.5岁。大多数已婚(81.7%)、居住在农村(54.5%)、已完成初等教育(52%),且未使用过现代避孕措施(84.5%)。在参与者中,10.4%处于包办婚姻,31%为意外妊娠,4%曾参与性交易。平均ANC就诊次数为四次。值得注意的是,99.6%的参与者至少患有一种合并症,3.2%患有两种或以上。最常见的合并症包括UTIs(53.0%)、贫血(34.8%)和HIV感染(8.7%)。较少见的疾病包括乙型肝炎(0.4%)、高血糖(7.4%)和子痫前期(1.2%)。结论 青少年妊娠中合并症患病率高,尤其是UTIs、贫血和HIV。改进这些疾病的筛查和管理可降低孕产妇和新生儿的发病率和死亡率。
Background Adolescent pregnancy presents significant health challenges worldwide. Each year, millions of teenage girls in developing regions become pregnant. In Uganda, teenage pregnancy remains common, with marked regional variations. Adolescents in low socioeconomic situations, with limited education, or who face barriers to contraceptive access are more prone to unintended pregnancies. These pregnancies may result in multiple health complications, including premature births, small for gestational age babies, postpartum depression, anaemia, and urinary tract infections (UTIs). Methods A cross-sectional study was conducted at the tertiary institution of Mbarara Regional Referral Hospital, Mbarara, Uganda, from July to September 2024, including adolescent pregnant women who presented for antenatal care (ANC) attendance or delivery. Data collection involved clinical examinations (blood pressure and mid-upper arm circumference (MUAC)) and laboratory tests (haemoglobin, HIV, hepatitis B, random blood sugar, and urinalysis). Data on socio-demographic and obstetric characteristics were collected through a structured questionnaire. Data were analysed using STATA version 17 (StataCorp LLC, College Station, TX, USA), with comorbidities defined by clinical criteria such as hypertension, anaemia, HIV infection, pre-eclampsia, hyperglycaemia, and UTIs. Results Of the total, 252 participants were enrolled. The median age was 18.5 years. Most were married (81.7%), rural residents (54.5%), had completed primary education (52%), and had not used modern contraceptives (84.5%). Among participants, 10.4% were in arranged marriages, 31% had unplanned pregnancies, and 4% had engaged in transactional sex. The average ANC attendance was four visits. Notably, 99.6% of participants had at least one comorbidity, and 3.2% had two or more. The most common comorbidities included UTIs (53.0%), anaemia (34.8%), and HIV infection (8.7%). Less common conditions included hepatitis B (0.4%), hyperglycaemia (7.4%), and pre-eclampsia (1.2%). Conclusion Adolescent pregnancies show a high prevalence of comorbidities, particularly UTIs, anaemia, and HIV. Improved screening and management of these conditions could reduce maternal and neonatal morbidity and mortality.
Onesmus Byamukama, Charles Tushabomwe-Kazooba, Michael Kanyesigye, Annah Amwikirize, Arnold Kamugisha, Moses Ntaro, et al. Comorbidities of Adolescent Pregnancy at a Tertiary Teaching Hospital in Southwestern Uganda.. Cureus. 2026; doi:10.7759/cureus.109957.
Onesmus Byamukama, Charles Tushabomwe-Kazooba, Michael Kanyesigye, Annah Amwikirize, Arnold Kamugisha, Moses Ntaro, et al (2026). Comorbidities of Adolescent Pregnancy at a Tertiary Teaching Hospital in Southwestern Uganda.. Cureus. https://doi.org/10.7759/cureus.109957
Onesmus Byamukama, Charles Tushabomwe-Kazooba, Michael Kanyesigye, Annah Amwikirize, Arnold Kamugisha, Moses Ntaro, et al. Comorbidities of Adolescent Pregnancy at a Tertiary Teaching Hospital in Southwestern Uganda.[J]. Cureus, 2026 doi:10.7759/cureus.109957.
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