描述逆行肾内手术中柔性和可导航抽吸输尿管入路鞘管的流量-压力关系
Characterizing the flow-pressure relationship for flexible and navigable suction ureteral access sheaths in retrograde intrarenal surgery.
摘要(中文译文)
探讨逆行肾内手术（RIRS）中使用柔性可导航吸引输尿管通道鞘（FANS）时灌注流量与肾内压（IRP）之间的关系，并确定维持IRP低于30 mmHg阈值所需的最大灌注流量。采用新鲜离体猪肾模型建立测压系统以测量IRP。通过穿刺入上、下肾盏的针管测量IRP。使用不同镜鞘比的柔性输尿管镜（F-URS）和FANS模拟RIRS。FANS连接负压吸引装置，吸引压力设定为0.02 MPa（150 mmHg）。在无吸引、排气口开放和排气口关闭条件下，记录不同灌注流量下的IRP，同时调整F-URS和鞘在肾内的位置。在镜鞘比为0.716时，无吸引和排气口开放条件下，灌注流量为150和250 ml/min时IRP超过30 mmHg的安全阈值。然而，在流量为300 ml/min时，排气口关闭条件下IRP仍低于安全阈值。在镜鞘比为0.75时，无吸引、排气口开放和排气口关闭条件下，灌注流量分别为150、250和300 ml/min时IRP超过30 mmHg。RIRS期间应用负压吸引时，FANS维持IRP低于30 mmHg阈值的最大灌注流量增加。此外，在相同负压条件下，最大灌注流量随镜鞘比增加而降低。
Abstract
To characterize the relationship between irrigation flow and intrarenal pressure (IRP), and determine the maximum irrigation flow rate for maintaining IRP below threshold of 30 mmHg during retrograde intrarenal surgery (RIRS) with the flexible navigable suction ureteral access sheath (FANS). Fresh ex vivo porcine kidney model were used to establish a manometric system for measuring IRP. IRP was measured through needle tubes punctured into the upper and lower calyces. Flexible ureteroscopes (F-URS) and FANS with varying scope-to-sheath ratios were used to simulate RIRS. The FANS was connected to a vacuum suction device with a suction pressure set at 0.02 MPa (150 mmHg). IRPs were recorded at different irrigation flow rates under no-suction, vent-open, and vent-close conditions, while adjusting the positions of the F-URS and sheath within the kidney. At a scope-to-sheath ratio of 0.716, IRPs exceeded the safe threshold of 30 mmHg at irrigation flow rates of 150 and 250 ml/min under no-suction and vent-open conditions. However, at a flow rate of 300 ml/min, IRPs remained below the safe threshold under vent-closed conditions. At a scope-to-sheath ratio of 0.75, IRPs exceeded 30 mmHg at irrigation flow rates of 150, 250, and 300 ml/min under no-suction, vent-open, and vent-close conditions, respectively. The maximum irrigation flow rate to maintain IRP below the 30 mmHg threshold for the FANS during RIRS increased with the application of negative pressure. Furthermore, under the same negative pressure conditions, the maximum irrigation flow rates decreased as the scope-to-sheath ratio increased.
如何引用
AMA
Haiwen Huang, Tianfu Ding, Daxun Luo, YangYang Xu, Yunfei Fan, Boxing Su, et al. Characterizing the flow-pressure relationship for flexible and navigable suction ureteral access sheaths in retrograde intrarenal surgery.. Scientific reports. 2026; doi:10.1038/s41598-026-59731-0.
APA
Haiwen Huang, Tianfu Ding, Daxun Luo, YangYang Xu, Yunfei Fan, Boxing Su, et al (2026). Characterizing the flow-pressure relationship for flexible and navigable suction ureteral access sheaths in retrograde intrarenal surgery.. Scientific reports. https://doi.org/10.1038/s41598-026-59731-0
GB/T 7714
Haiwen Huang, Tianfu Ding, Daxun Luo, YangYang Xu, Yunfei Fan, Boxing Su, et al. Characterizing the flow-pressure relationship for flexible and navigable suction ureteral access sheaths in retrograde intrarenal surgery.[J]. Scientific reports, 2026 doi:10.1038/s41598-026-59731-0.
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