具有既往心理健康挑战和长期新冠肺炎的种族化加拿大人的症状、功能和工作参与情况：一项横断面研究
Symptom, Functional, and Work Participation Profiles Among Racialized Canadians with Pre-Existing Mental Health Challenges and Long COVID: A Cross-Sectional Study.
摘要(中文译文)
长新冠（Long COVID）与持续的多系统症状相关，但人们对其如何影响具有交叉脆弱性的个体——例如种族化身份与既存心理健康状况——知之甚少。本研究旨在对这一人群的症状负担、功能结局和心理健康进行描述性刻画。研究在加拿大51名自认为种族化、具有既存心理健康状况并报告长新冠症状的成年人中开展了一项横断面探索性研究。参与者完成了一项在线调查，其中包括对症状、疲劳、劳力后不适、认知功能、心理健康和残疾的经验证测量工具。采用描述性统计对结局进行总结。参与者报告总体症状负担为轻度至中度，呼吸和心理领域的得分最高。在工作、社交和日常活动方面的功能损害为中度（工作与社会适应量表均值=17.35；世界卫生组织残疾评定量表2.0均值=16.61；新冠后功能状态量表均值=2.20）。疲劳和劳力后不适较为显著（改良疲劳影响量表均值=43.39；DePaul症状问卷-劳力后不适均值=22.47），认知困难亦常被报告（感知缺陷问卷均值=33.43）。焦虑和抑郁得分分别处于轻度和中度范围（广泛性焦虑障碍量表-7均值=9.27；患者健康问卷-9均值=11.43）。研究发现了具有临床意义的疲劳、劳力后不适和抑郁，同时各生活领域存在中度功能受限。研究结果支持将长新冠概念化为一种协同病（syndemic）状况，并强调需要开展以公平为导向的研究、康复和公共卫生策略。
Abstract
Long COVID is associated with persistent, multi-system symptoms, yet little is known about how it affects individuals with intersecting vulnerabilities, such as a racialized identity and pre-existing mental health conditions. This study aimed to descriptively characterize the symptom burden, functional outcomes and mental health in this population. A cross-sectional, exploratory study was conducted among 51 adults in Canada who self-identified as racialized and as having a pre-existing mental health condition and reported long COVID symptoms. Participants completed an online survey, including validated measures of symptoms, fatigue, post-exertional malaise, cognitive function, mental health and disability. Descriptive statistics were used to summarize outcomes. Participants reported a slight to moderate overall symptom burden, with the highest scores in respiratory and psychological domains. Functional impairment was moderate across work, social and daily activities (Work and Social Adjustment Scale mean = 17.35; World Health Organization Disability Assessment Schedule 2.0 mean = 16.61; Post COVID-19 Functional Status Scale mean = 2.20). Fatigue and post-exertional malaise were notable (Modified Fatigue Impact Scale mean = 43.39; DePaul Symptom Questionnaire-Post-Exertional Malaise mean = 22.47), and cognitive difficulties were commonly reported (Perceived Deficits Questionnaire mean = 33.43). Anxiety and depression scores were in the mild to moderate range respectively (General Anxiety Disorder-7 mean = 9.27; Patient Health Questionnaire-9 mean = 11.43). Clinically relevant fatigue, post-exertional malaise, and depression were found, alongside moderate functional limitations across life domains. The findings support the conceptualization of long COVID as a syndemic condition and underscore the need for equity-informed research, rehabilitation and public health strategies.
如何引用
AMA
Maryam Shahzad, Sana Siddiqui, Chloe Lau, De-Lawrence Lamptey, Victor E Ezeugwu, Geoffrey Maina, et al. Symptom, Functional, and Work Participation Profiles Among Racialized Canadians with Pre-Existing Mental Health Challenges and Long COVID: A Cross-Sectional Study.. Healthcare (Basel, Switzerland). 2026; doi:10.3390/healthcare14121726.
APA
Maryam Shahzad, Sana Siddiqui, Chloe Lau, De-Lawrence Lamptey, Victor E Ezeugwu, Geoffrey Maina, et al (2026). Symptom, Functional, and Work Participation Profiles Among Racialized Canadians with Pre-Existing Mental Health Challenges and Long COVID: A Cross-Sectional Study.. Healthcare (Basel, Switzerland). https://doi.org/10.3390/healthcare14121726
GB/T 7714
Maryam Shahzad, Sana Siddiqui, Chloe Lau, De-Lawrence Lamptey, Victor E Ezeugwu, Geoffrey Maina, et al. Symptom, Functional, and Work Participation Profiles Among Racialized Canadians with Pre-Existing Mental Health Challenges and Long COVID: A Cross-Sectional Study.[J]. Healthcare (Basel, Switzerland), 2026 doi:10.3390/healthcare14121726.
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