尼泊尔三级医疗中心终末期肾衰竭患者对血液透析依从性感知重要性影响因素
Factors influencing perceived importance of haemodialysis adherence among end stage kidney failure patients in tertiary care centres in Nepal.
摘要(中文译文)
慢性肾衰竭是一个重大的全球公共卫生问题，需要肾脏替代治疗如透析。对透析依从性重要性的认知有助于决定患者如何理解和互动于影响透析依从性的态度、想法和行为。本研究旨在评估尼泊尔三级医疗中心终末期肾衰竭患者对血液透析依从性重要性的认知及其相关因素。这是一项于2025年5月至8月在尼泊尔两个三级医疗中心开展的横断面研究，纳入18岁及以上接受血液透析的患者。结局变量为对透析依从性重要性的认知，采用终末期肾病依从性问卷（ESRD-AQ）进行测量。自变量为社会人口学特征、透析相关特征及可及性因素。在研究的283名血液透析患者中，平均年龄为50.6岁，与已婚患者相比，单身患者的良好认知患病率更高（91%）[APR（调整患病率比）：1.12；95% CI（置信区间）：1.03-1.21]，与无父母陪伴的患者相比，有父母陪伴的患者良好认知患病率也更高（APR：1.14；95% CI：1.01-1.28）。该研究显示患者对血液透析依从性的认知良好，尤其是在单身患者和有父母陪伴的患者中。
Abstract
Chronic Kidney Failure is a significant global public health concern requiring kidney replacement therapy such as dialysis. Perception of the importance of adhering to dialysis helps to determine how patients interpret and interact with the influencing attitude, thoughts and behaviours towards adhering to dialysis. This study aimed to assess the perception of the importance of adherence to haemodialysis and its associated factors among end-stage Kidney failure patients in tertiary care centres in Nepal. This was a cross-sectional study conducted from May to August 2025 in two tertiary care centres in Nepal that included patients undergoing hemodialysis aged 18 years and above. The outcome variable was perception of the importance of adherence to dialysis and was measured using The End Stage Renal Disease Adherence Questionnaire (ESRD-AQ). The independent variables were socio-demographics, dialysis-related characteristics and accessibility factors. Among 283 hemodialysis patients in the study, their mean age was 50.6 years with higher prevalence of good perception (91%) among single [APR (adjusted prevalence ratio):1.12; 95% CI (confidence interval): 1.03-1.21)] and parents accompanying patients (APR:1.14; 95% CI:1.01-1.28) compared to married, and non-parent accompanying patients respectively. The study showed good perception of hemodialysis adherence, especially among singles and those accompanied by their parents.
如何引用
AMA
Pramita Shrestha, Anisha Koirala, Prajwal Satyal, Ashish Mani Bhurtel, Biraj Man Karmacharya. Factors influencing perceived importance of haemodialysis adherence among end stage kidney failure patients in tertiary care centres in Nepal.. PloS one. 2026; doi:10.1371/journal.pone.0351702.
APA
Pramita Shrestha, Anisha Koirala, Prajwal Satyal, Ashish Mani Bhurtel, Biraj Man Karmacharya (2026). Factors influencing perceived importance of haemodialysis adherence among end stage kidney failure patients in tertiary care centres in Nepal.. PloS one. https://doi.org/10.1371/journal.pone.0351702
GB/T 7714
Pramita Shrestha, Anisha Koirala, Prajwal Satyal, Ashish Mani Bhurtel, Biraj Man Karmacharya. Factors influencing perceived importance of haemodialysis adherence among end stage kidney failure patients in tertiary care centres in Nepal.[J]. PloS one, 2026 doi:10.1371/journal.pone.0351702.
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