Annual Review of Chemical and Biomolecular Engineering化学与生物分子工程年度综述
Annual Review of Chemical and Biomolecular Engineering(英文缩写 ANNU REV CHEM BIOMOL),ISSN 1947-5438,eISSN 1947-5446,中文译名:化学与生物分子工程年度综述 是一本学术期刊。本页汇总该期刊的最新影响因子、分区信息以及最新收录于 PubMed 的文献,帮助您快速了解期刊全貌。
发文量统计区间：2025-09-28 至 2026-09-28，按本站收录文献的发表日期统计。
期刊介绍
历年影响因子趋势
| JCR 数据年份 | 影响因子 | JCR 分区 |
|---|---|---|
| 2021 | 9.700 | Q1 |
| 2022 | 8.400 | Q1 |
| 2023 | 7.600 | Q1 |
| 2024 | 12.800 | Q1 |
| 2025 | 13.100 | Q1 |
Annual Review of Chemical and Biomolecular Engineering 最新收录文献
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1. Sustainable Refrigerants, Policy Drivers, and Emerging Technologies.
PMID:日期:2026-06-01Heating, ventilation, air conditioning, and refrigeration (HVACR) systems are essential across residential, commercial, and industrial sectors but are critical energy consumers, and their refrigerant emissions and energy use present a major challenge to global sustainability goals. This state-of-the-art review moves beyond tracing the evolution of refrigerants to evaluate key international agreements, including the Kigali Amendment, and national regulations as primary drivers of the transition to sustainable refrigerants. It critically assesses current sustainable alternatives, including natural refrigerants and low-global warming potential synthetic options, such as hydrofluoroolefins, highlighting the trade-offs in their technical application, economic viability, safety, and infrastructure implications. Emerging solutions, including not-in-kind cooling technologies, innovative thermodynamic cycles, advanced materials, artificial intelligence, digitalization, and refrigerant lifecycle management, are examined to provide critical perspectives and guide future research, development, and deployment. By integrating regulatory, market, and technological insights, this review offers a comprehensive road map toward a sustainable, low-emission, and energy-efficient HVACR sector.
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3. A Resonant Life.
3. 和谐的生活PMID:日期:2026-06-01I embody the quintessential Californian spirit: Raised in Los Angeles, I spent weekends either at the beach or skiing at Big Bear, rode motorcycles, hiked the Sierras, and cherished the sounds of the Beach Boys and Creedence Clearwater Revival. Restless, undisciplined, and irreverent, I applied to only one college-UC Santa Barbara-mainly because that is where my high school friends were going. Although we like to think our intellect transcends culture, my childhood and teenage years were shaped by the rhythms of the 1960s: space flight, NASA, and virtually every episode of (often watched multiple times). Unmoored, I entered college intending to major in biochemistry but drifted into chemistry while also immersing myself in the physics curriculum. I earned a PhD in chemical physics at Caltech, yet chose to work with a chemical engineer. When my thesis advisor was suddenly killed, I completed my dissertation at Xerox Palo Alto Research Center, working on solar cell materials alongside Cambridge-educated physicists. While my chemistry peers pursued academic postdocs, I went instead to IBM Yorktown Heights, dividing my time between silane reactor engineering and amorphous semiconductor physics. Would I ever become anchored? Here is the rest of the story that led to 43 years on the Berkeley faculty. Including motorcycles.
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4. Jamming and Yielding in Dense Suspensions.
PMID:日期:2026-06-01Suspensions of particles dispersed in liquids are ubiquitous materials in industry and geophysics; relevant examples include cement and mud. At high particle concentration, in what is called a dense suspension, crowding induces multiscale interactions ranging from local, particle-level contact forces to macroscopic, system-spanning contact networks that dynamically evolve under applied shear. As the number of constraints on relative particle movement increases, the suspension viscosity rises, and eventually the material reaches a jammed state. In this review, we discuss frameworks developed to predict the rheological behavior of dense suspensions in the vicinity of jamming and describe the resulting flow-state diagram. Going beyond mean-field models, we discuss recent advances in understanding the contact network of spatially correlated particles. We also review recent developments for tailoring flow constraints at the particle level, both by particle geometry and by interactions induced by chemical bonds, which can be used to engineer the location and extent of different regimes in the flow-state diagram. We end with a set of issues and perspectives for future research, including possible ways to extend the current theoretical framework, apply simulations to suspensions comprising particles with more complex nonspherical or highly anisotropic shapes, and develop approaches to predict how molecular-scale details influence macroscopic flows.
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5. Beyond Clean: Unraveling Phase Behavior and Rheology of Soaps.
PMID:日期:2026-06-01Soaps are some of the oldest surfactants known to humans and remain indispensable in modern health, personal care, and sustainability agendas. Still, the simple chemistry of salts of fatty acids reveals a rich, multiscale landscape of self-assembly and flow behavior that controls soap processing and sensorial attributes. This review integrates phase behavior with rheological analysis to demonstrate how distinct microstructures, ranging from micellar to liquid-crystalline phases, possess unique rheological signatures. We further demonstrate how the coexistence and combination of these phases in a product such as a soap bar introduce additional levels of structural and rheological complexity. In addition, we highlight how linear viscoelastic analysis resolves relaxation hierarchies and how yield stress and thixotropic responses are inherent to the multiphase brick-and-mortar microstructures in products such as soap bars. The complex rheology of soap bars necessitates constitutive models that incorporate elasticity, plasticity, and time-dependent structure to predict extrusion or stamping performance. We also explore how the microstructure relates to cleaning efficacy, foam richness, lather dynamics, and rinse feel by coupling rheology measures with in-use dilution behavior. Finally, we discuss open questions, challenges, and future directions for developing more sustainable products.
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6. The Nonequilibrium Self-Consistent Generalized Langevin Equation Theory of Glasses and Gels.
PMID:日期:2026-06-01The nonequilibrium self-consistent generalized Langevin equation theory of irreversible processes in liquids is a first-principles approach that allows for the derivation of general equations that describe the out-of-equilibrium and nonstationary relaxation of a liquid after a sudden quench or compression into an amorphous state. Proposed in 2010, the theory has since been systematically applied to describe a wide variety of model systems, with predictions rigorously and successfully validated against both experimental and simulated results. In this work, we briefly review the progress of this theoretical framework over the past 15 years, focusing on its applications to the description of the structural, dynamical, and rheological behavior of model glass- and gel-forming systems.
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7. Molecular Understanding of Free-Energy Landscapes.
PMID:日期:2026-06-01Free-energy surfaces (FESs) offer a unifying framework for understanding molecular-level structures, transformations, and thermodynamic stability. They distill the complexity of atomistic simulations into interpretable landscapes of metastable states, bridging molecular-level detail with macroscopic observables. This review provides researchers in molecular simulations, computational physical chemistry, and chemical engineering with a conceptual and practical guide to computing and interpreting FESs, from their statistical-mechanical foundations to modern machine learning approaches that are transforming the sampling, representation, and analysis of molecular systems.
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8. Protein Vesicles as Emerging Platforms for Drug Delivery, Vaccines, and Immunotherapy.
PMID:日期:2026-06-01Protein vesicles are spherical, hollow structures made entirely of folded proteins, fusion proteins, or polypeptides. Their intrinsic biocompatibility, nontoxicity, structural tunability, and cargo-loading capacity make them promising candidates for diverse biomedical applications. Although diverse forms of protein-based carriers have long been employed in drug, gene, and vaccine delivery, as well as in artificial antigen-presenting cells, vesicle architectures provide distinct advantages over free proteins, including enhanced stability, targeted delivery, and controlled release. We summarize recent advances in engineering protein vesicles and assess their current status within the broader landscape of synthetic vesicles in biomedicine. By comparing protein vesicles with liposomes, polymersomes, and virus-like particles, we highlight the limitations of conventional systems and underscore the unique benefits of protein-based assemblies. We further examine the emerging applications of protein vesicles in therapeutic delivery, diagnostics, and immunotherapy and discuss future directions needed to advance protein vesicle technologies toward clinical translation.
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9. Strategies to Improve the Stability and Translation of Therapeutic mRNAs.
PMID:日期:2026-06-01Therapeutic messenger RNAs (mRNAs) offer a versatile platform for treating a wide range of diseases, but their clinical efficacy hinges on optimizing both stability and translational efficiency. This review summarizes recent advances in strategies to enhance mRNA performance, with a focus on human therapeutics. We discuss secondary structure optimization, including artificial intelligence-guided design tools like RNAdegformer and LinearDesign, which balance structural stability and translational output. The roles of 5' and 3' untranslated regions in ribosome recruitment and mRNA decay are examined, highlighting sequence motifs and empirical design strategies that facilitate these processes. Chemical modifications, such as pseudouridine substitution, are shown to improve stability and reduce immunogenicity. Emerging approaches using circular RNA further extend transcript longevity. Finally, we review delivery technologies, including lipid nanoparticles, polymers, and extracellular vesicles, that protect mRNA and enable targeted cellular uptake. Together, these advances provide a road map for developing stable, efficient, and clinically viable mRNA-based therapeutics.
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10. Advancing Genetic Code Expansion in Live Cells Through Metabolic Engineering.
PMID:日期:2026-06-01Genetic code expansion (GCE) is the ability to encode polypeptide building blocks beyond the standard 20 the ribosome uses for protein translation, known as nonstandard amino acids (nsAAs). The broadening of chemical functionalities in proteins produced by live cells has generated substantial value across fundamental and applied research settings. However, a common limitation of GCE approaches is their reliance on the supplementation of chemically synthesized nsAAs to cell culture media. To overcome this limitation of nsAA sourcing, efforts have engineered systems for nsAA biosynthesis, often in the same host that performs GCE. In recent years, these works have reported new chemical targets obtained through biosynthesis, as well as additional rationale for combining metabolic engineering and GCE, particularly for synthetic biology applications. Here, we review this rapidly advancing field and provide our perspectives on technical and conceptual innovations.