COMPTES RENDUS BIOLOGIEScomptes rendus 生物学
COMPTES RENDUS BIOLOGIES(英文缩写 CR BIOL),ISSN 1631-0691,eISSN 1768-3238,中文译名:comptes rendus 生物学 是一本学术期刊。本页汇总该期刊的最新影响因子、分区信息以及最新收录于 PubMed 的文献,帮助您快速了解期刊全貌。
发文量统计区间：2025-09-27 至 2026-09-27，按本站收录文献的发表日期统计。
期刊介绍
历年影响因子趋势
| JCR 数据年份 | 影响因子 | JCR 分区 |
|---|---|---|
| 2021 | 2.357 | Q3 |
| 2022 | 2.000 | Q3 |
| 2023 | 0.700 | Q4 |
| 2024 | 0.600 | Q4 |
| 2025 | 0.800 | Q4 |
COMPTES RENDUS BIOLOGIES 最新收录文献
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1. Sexual dimorphisms in juvenile development under nutritionnal stress.
PMID:日期:2026-08-28Nutrition is a fundamental regulator of juvenile development. The persistently high global prevalence of childhood undernutrition and consequent stunting underscores the urgent need to better understand how nutritional status shapes developmental trajectories. Biological sex has recently emerged as a key risk factor for stunting, with boys consistently exhibiting greater vulnerability. This review examines the biological basis of sex differences in physiological adaptation to nutritional stress, focusing specifically on dietary protein deficiency during the juvenile period. Two critical developmental processes display pronounced sexual dimorphism under protein restriction: linear growth and reproductive maturation. Evidence from both preclinical and clinical studies indicates that juvenile protein restriction differentially affects these processes in males and females, highlighting the necessity of considering sex as a biological variable in experimental design and data interpretation. Shared endocrine signals, including Fibroblast Growth Factor 21, may contribute to these sex-specific adaptive responses. Further elucidating the nutritional, endocrine and metabolic mechanisms underlying sexually dimorphic outcomes of juvenile development is essential for enhancing the mechanistic value and translational relevance of preclinical and clinical research.
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2. The value of "One Health" modelling in zoonotic diseases epidemiology and public health.
PMID:日期:2026-08-17Assessing the impact of control and prevention strategies on zoonotic diseases in human populations requires the use of formal modelling frameworks, integrating animal, environmental and human data. However, such quantitative "One Health" approaches to guide public health interventions are, to date, overlooked. Their implementation could be facilitated by improved access to epidemiological, demographic, and contact data on different hosts, by improved training of epidemiologists and modellers through relevant multidisciplinary research career paths, and finally by improving institutional support for better visibility.
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3. Development is an evolutionary phenomenon.
PMID:日期:2026-08-12EvoDevo called homeotic genes "architect genes" because they "control" "body plans". The first metaphor involves purposefulness and brings finalism; the second one is cybernetic; the third one is idealistic/platonic. These are three ways of thinking that are incompatible with today's evolutionary theory. Using such ordering causal factors, EvoDevo partly stayed outside biology-and evolution as well-because in biology, order is not causal: it is a consequence that we need to explain. Natural selection is one of the concepts explaining the rise of apparent short-term biological order, or regularities. We no longer need the verb "to control" [Nijhout, Prog. Biophys. Mol. Biol., 169-170 (2022)]. Since genes are controlled [Noble, Interface Focus, 7 (2017)], just as much as they control, the notion of control in this context is not appropriate. It would be better to speak of "contribution". Natural selection and descent with modification, the two pillars of the Darwinian approach to life [Gayon, C. R. Palevol, 8 (2009)], are entering the soma. They are not restricted to the functioning of the adult soma, but also to the entire developing soma, avoiding "adultocentrism" [Minelli, Toward a Theory of Development (2014)]. The first pillar, natural selection within the body, anticipated by [Roux, Der Kampf der Teile im Organismus: Ein Beitrag zur Vervollständigung der Mechanischen Zweckmässigkeitslehre (1881); Roux, La lutte des parties dans l'organisme (2013)], but occulted during the past century [Heams, La lutte des parties dans l'organisme (2013b)], is now helping to explain cancer dynamics, aging, neurogenesis, etc. With the second pillar, it is now possible to construct the phylogeny of cells of a single developing organism, or to perform a phylogenetic analysis of metastases from a single patient. Ontogenesis and phylogenesis are no more two distinct processes: natural selection and descent with modification both contribute to explain both the developing individual and its stability, as well as the regularity of individuals of a same population from which we name species. The two pillars of evolutionary theory-descent with modification and natural selection-do occur within the developing organism itself and the resulting phenomenon is ontophylogenesis [Kupiec, L'ontophylogenèse. Évolution des espèces et développement de l'individu (2012)], which is actually studied by EvoDevo.
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4. Integrating intraspecific trait variation and spatiotemporal variability of selection as levers of action in forest management.
PMID:日期:2026-07-02Adaptation is a polysemous word referring both to the state of being adapted and to the selection processes leading to this state. However, considering population adaptation only as an ultimate achievement in a static rather than dynamic perspective may lead to a double misperception: (i) that all adapted populations have depleted variation of adaptive traits and, therefore, low evolvability, and (ii) that adaptation systematically requires many generations. This static vision of adaptation as an achievement is particularly inappropriate for long-lived organisms like trees that continuously respond to selection and retain high levels of adaptive trait variation. This review proposes a baseline for a process-based approach of adaptation in trees, shedding new light on current challenges for forest management and forest genetic resources conservation in the context of global change.A first general section uses the genes-traits-fitness mapping framework to explore the effect of selection on different types of traits, depending on their links to other traits and fitness. In a second section, trait variation and coordination patterns observed in forest trees are interpreted in terms of biological constraints and response to selection. A third section investigates, for trees, how the genes-traits-fitness map varies in space and time with environmental conditions and developmental stages, resulting in spatiotemporal variability of selection. A fourth section reviews the impacts of forestry interventions on trait variation and selection. The conclusive section illustrates the integration of selection as a dynamic and partly manageable process in management thinking for forest genetic resource sustainable use and conservation.
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5. [Managing mixed forest stands : bridging the gap between silviculture and ecological theory].
PMID:日期:2026-06-26In this article, we illustrate the value of combining ecological theory and silviculture through the example of continuous cover forestry in mixed stands and the use of a forest dynamics model that addresses research questions in ecology and biogeography (MATREEX). In a context where diversification is a strategy promoted for the adaptation of forests to climate change, we explore how different species coexistence mechanisms (negative frequency dependence, relative nonlinearity, recruitment-survival trade-off) can be translated into silvicultural actions and test their effectiveness in terms of species coexistence. Our study focuses on two types of mixed stands known to be difficult to manage between sessile oak (Quercus petraea (Matt.) Liebl.) and common beech (Fagus sylvatica L.), on the one hand, and silver fir (Abies alba Mill.) and Scots pine (Pinus sylvestris L.), on the other hand.We show that preferential selection of the most abundant species (negative frequency dependence), which is easy to implement and already used in forest management, is very effective in favouring the least competitive species in the stand. The other mechanisms tested have only a limited influence on species proportions. Although these results must be interpreted with caution, taking into account the limitations of the model used, they provide initial findings that can be explored further using other approaches and give rise to hypotheses that can be tested in situ.
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6. [Which forests for which biodiversity under climate change?]
PMID:日期:2026-06-12Environmental changes, including climate change, put forest biodiversity under an unprecedented pressure. Yet, biodiversity plays a key role in the functioning of forest ecosystems and the quality of the services they provide to human societies. The spontaneous or "facilitated" adaptation of forests to climate change represents a new challenge for forest science and engineering. One challenge is to mobilize biodiversity to increase the resilience of forest ecosystems and preserve their functional integrity in the face of intensifying stresses and increased disturbance frequency. I first discuss three prerequisites: (i) understanding biodiversity as the legacy of local, regional, and global histories; (ii) considering biodiversity as a functional attribute of forest ecosystems; (iii) considering biodiversity as species assemblages that are patterned by natural and anthropogenic forcings that, in turn, affect the ecosystem's resilience to these forcings. I then analyze the foreseeable consequences for biodiversity of the three strategies currently implemented for forest adaptation in metropolitan France: free evolution of forests; managing forests to increase their resilience; and replacing existing forests with plantations of (often exotic) tree species supposed to be better adapted to forthcoming climate conditions. For each strategy, I outline a benefit/risk assessment. I conclude with the imperative need to revisit forest engineering based on the scientific outputs of functional ecology, where biodiversity-which is not limited to the number of tree species-is not an obstacle to forest management, but a lever for adaptation.
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7. {"_":"[Impacts of climate change on the functioning and productivity of agroecosystems: a focus on the impact of interactions between CO, temperature and water deficit].","sub":["2"]}
PMID:日期:2026-06-04Rising atmospheric CO2 concentrations and temperatures, as well as changes in water regimes, are major determinants of the functioning and productivity of agroecosystems. Although the individual effects of each of these factors have been extensively studied, their combined action remains poorly understood, despite the fact that these factors interact closely to shape future climate conditions. This article provides a synthesis of current knowledge on the combined impacts of rising CO2, temperatures and water deficiency on crop plants, with a particular focus on wheat. Following a review of the experimental setups used to study these interactions, we analyse the ecophysiological and agronomic responses of plants to different combinations of climatic factors, distinguishing between specific effects, interactions and compensatory mechanisms. Results from recent syntheses and meta-analyses highlight a high degree of variability in responses, depending on species, genotypes, phenological stages and experimental conditions. Experimental results, across all experimental setups, show in particular that the fertilising effect of CO2 does not generally compensate for the negative impacts of water and heat stress, particularly when these are combined. Finally, this article discusses the implications of these results for crop modelling and the prediction of agroecosystem productivity trajectories in a climate change context, emphasising the need to explicitly integrate interactions between climatic factors, biological processes and genetic variability.
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8. Autogenic transitions in individuality.
PMID:日期:2026-06-02Major evolutionary transitions in individuality occur when previously independent entities become components of a new unit whose parts share a reproductive fate. Most discussions focus on transitions arising through the integration of independent lineages. Less attention has been given to the possibility that transitions might originate from within a lineage, where internally generated components become incorporated into the parent-offspring system and inherited as part of a higher-level individual. Such cases would constitute what I term autogenic transitions in individuality. Biological and cultural precedents in which lineages generate novel entities that subsequently influence their own evolution are first examined. In most cases such innovations remain embedded within existing individuals, although transmissible cancers demonstrate that internally generated lineages can also form distinct Darwinian populations. These comparisons clarify the conditions under which internally generated systems might give rise to new evolutionary individuals. The emergence of artificial intelligence (AI), and its growing entanglement with human development and social organisation, make it timely to examine such possibilities. Three routes are considered: (1) centralised, non-replicating AI systems that influence human evolution through persistent creation of conditions that cause selection to work at the collective level; (2) replicating AI lineages capable of entering egalitarian associations with humans; (3) AI systems transmitted across generations as components of the human developmental system. The first alters selection without generating reproduction of the composite, whereas the latter two create conditions under which humans and AI could form evolving composite lineages. Autogenic transitions therefore extend evolutionary theory by identifying routes by which new evolutionary individuals may arise when components generated within a lineage become incorporated into systems of reproduction and inheritance, and by helping to recognise plausible transitions that might otherwise be overlooked because such components first appear as subordinate products or tools rather than as candidate parts of a new evolutionary individual.
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9. Assessing the potential effects of climate change on future forest composition in France.
PMID:日期:2026-05-21Climate change is already affecting French forests: rising temperatures, altered precipitation, and more frequent extreme events are driving shifts in species distributions, reduced productivity, and increased tree mortality. Anticipating future forest composition requires understanding species' exposure to future climatic conditions, their sensitivity to these conditions, and their capacity to adapt or migrate. Regional contrasts are marked, with stronger warming and drying in northeastern and Mediterranean regions, while parts of western France are comparatively less affected. Observations show high vulnerability of temperate species such as Fagus sylvatica and Picea abies, whereas Mediterranean species (e.g. Pinus pinaster, P. halepensis) appear more resistant at present.Future changes will depend on climate change evolution intensity, site and stand characteristics, species composition, and adaptive capacity. Initially, adaptive management-adjusting stand structure, promoting diversity, and managing density, water, and species selection-can mitigate impacts and buy time. Under higher vulnerability, species replacement may become necessary-ideally by favoring drought-tolerant species already present through natural regeneration, or otherwise through assisted migration using drought-adapted provenances of native species or non-native species with suitable traits. Uncertainties about ecosystem resilience and the effectiveness of management measures underline the need for integrative, site-specific strategies to sustain ecosystem services and effectively guide future forest composition under ongoing climate change.
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10. Adhesion-mediated force transmission regulates cell competition in epithelia.
PMID:日期:2026-05-13Organs and tissues consist of a precise arrangement of different cell types, all playing a specific role to fulfil the biological function of the tissue. Small changes in cellular phenotypes or behaviour can lead to developmental defects, tissue malfunctions or the emergence of diseases. Therefore, tissue integrity, health and function are maintained through different quality control mechanisms. One highly conserved mechanism is cell competition, through which cells of reduced fitness are eliminated. Cells can employ various strategies to eliminate each other. Those include the exertion of mechanical forces, but its role in determining the competition outcome remains unclear. Here, we report that heterogeneities in force transmission capabilities mediated by cell-cell adhesion differences lead to cell competition. We show that increased force transmission endows collectives of cells with a fitness advantage, as it provides increased resistance to elimination forces. Elimination forces are generated from large stress fluctuations, emerging at the interfaces of competing cell populations. Besides promoting the removal of unfit cells in a wide range of biological conditions where local cell-cell adhesion heterogeneities are observed, this mechanism might be of general importance for the generation and maintenance of tissue boundaries.