OTOLARYNGOLOGY-HEAD AND NECK SURGERY耳鼻咽喉头颈外科学
OTOLARYNGOLOGY-HEAD AND NECK SURGERY(英文缩写 OTOLARYNG HEAD NECK),ISSN 0194-5998,eISSN 1097-6817,中文译名:耳鼻咽喉头颈外科学 是一本学术期刊。本页汇总该期刊的最新影响因子、分区信息以及最新收录于 PubMed 的文献,帮助您快速了解期刊全貌。
发文量统计区间：2025-09-27 至 2026-09-27，按本站收录文献的发表日期统计。
期刊介绍
历年影响因子趋势
| JCR 数据年份 | 影响因子 | JCR 分区 |
|---|---|---|
| 2021 | 5.591 | Q1 |
| 2022 | 3.400 | Q1 |
| 2023 | 2.600 | Q1 |
| 2024 | 2.500 | Q1 |
| 2025 | 2.600 | Q1 |
OTOLARYNGOLOGY-HEAD AND NECK SURGERY 最新收录文献
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1. Impact of Solid Organ Transplant History on Outcomes in Head and Neck Microvascular Reconstruction.
PMID:期刊:日期:2026-09-25To evaluate short-term postoperative outcomes and long-term survival following head and neck free tissue transfer (FTT) in solid organ transplant (SOT) recipients compared with matched non-transplant patients. Retrospective matched cohort study. Two tertiary academic centers and a national database (TriNetX). Adult patients undergoing head and neck FTT were identified from prospectively maintained multi-institutional databases and TriNetX. SOT recipients were matched 1:1 with non-SOT controls using propensity score matching. Primary outcomes included 30-day postoperative mortality and complications. Secondary outcomes included long-term overall survival (OS) and disease-free survival (DFS). In the multi-institutional cohort (36 SOT recipients matched to 36 controls), surgical and flap complications were comparable, but SOT recipients had higher rates of deep vein thrombosis (DVT) and urinary tract infection (UTI). Thirty-day mortality was higher among SOT recipients (11.1% vs 0%); CCI-adjusted Firth regression showed borderline increased odds of early mortality (OR 10.74; 95% CI 0.97-1494.70; p = 0.054). The DVT association attenuated to non-significance after adjusting for prior DVT/PE (OR 2.18; p = 0.654); UTI remained associated (OR 24.36; p = 0.002). OS was lower in SOT recipients at 1, 3, and 5 years (HR 2.16; 95% CI 1.06-4.42); DFS did not differ. In the TriNetX cohort (136 matched pairs), 30-day outcomes were similar; OS remained reduced at 3 and 5 years (HR 1.48; 95% CI 1.04-2.11). While perioperative outcomes are comparable, SOT recipients face higher medical complications, worse long-term survival, and possible increased early mortality, underscoring the need for careful selection and vigilant follow-up.
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2. Diagnosis and Management of Suprastomal Collapse After Pediatric Tracheostomy: A Phenotype-Directed Surgical Algorithm.
PMID:期刊:日期:2026-09-25To report institutional outcomes in pediatric suprastomal collapse and to describe a structured, phenotype-directed diagnostic and surgical management framework grounded in dynamic airway assessment and morphology-based operative selection. STUDY DESIGN: Retrospective cohort study. Tertiary pediatric airway reconstruction center. Consecutive pediatric patients undergoing operative correction of suprastomal collapse between December 2020 and July 2024 were reviewed. All patients underwent rigid bronchoscopy followed by dynamic flexible bronchoscopy after tracheostomy tube removal. Collapse was classified as anterior, posterior, lateral, or combined according to dynamic behavior, segment length, and cartilage integrity. Operative intervention was selected based on phenotype and structural characteristics. The primary outcome was successful decannulation. Twenty-five patients underwent 28 procedures. Mean age at first intervention was 6.3 years (range 0.8-21.2 years). Anterior or combined collapse was present in 18 patients and treated with primary anterior closure (n = 5), anterior external bioresorbable stent reinforcement (n = 4), tracheal resection and reconstruction (n = 7), or slide tracheoplasty (n = 2); all were successfully decannulated. Posterior collapse (n = 4) treated with posterior external stent tracheopexy achieved 75% decannulation. Lateral collapse (n = 3) treated with vertical external stenting achieved 100% decannulation. Overall decannulation success was 92%. Suprastomal collapse represents a heterogeneous spectrum of localized airway instability rather than a uniform pathologic entity. Phenotype-directed operative selection based on dynamic bronchoscopic classification is associated with favorable decannulation outcomes and offers a reproducible framework for surgical decision-making.
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3. Influence of Vitamin B12 Deficiency on Auditory and Vestibular Functioning: An Objective Test-Based Systematic Review.
PMID:期刊:日期:2026-09-25To evaluate the effectiveness of objective audiological and vestibular assessments in detecting functional changes associated with vitamin B12 deficiency. A comprehensive literature search was conducted in PubMed, Scopus, Web of Science, and EMBASE databases. This PROSPERO-registered systematic review (CRD420251049105) followed a structured search strategy based on the PICO framework. Two independent reviewers screened titles, abstracts, and full texts of eligible studies. Data extraction and quality assessment were performed independently using the Mixed Methods Appraisal Tool (MMAT), with disagreements resolved by a third reviewer. Studies investigating objective auditory and vestibular assessments, including Auditory Brainstem Response (ABR), Otoacoustic Emissions (OAE), and Vestibular Evoked Myogenic Potentials (VEMP), in individuals with vitamin B12 deficiency were included. Eleven studies met the inclusion criteria. Evidence suggests that vitamin B12 deficiency affects neural conduction and cochlear function, as demonstrated by prolonged ABR latencies and reduced Transient Evoked OAEs (TEOAE) and Distortion Product OAEs (DPOAE) amplitudes. Vestibular findings were inconsistent, with some studies reporting absent cVEMP responses and others finding no significant association in ENG/VNG assessments. In infant populations, vitamin B12 supplementation resulted in partial or complete recovery of auditory conduction. Vitamin B12 deficiency adversely affects neural transmission and cochlear micromechanics. Objective electrophysiological assessments, such as ABR and OAE, are sensitive indicators of subclinical neuropathy. Although vestibular involvement remains inconclusive, integrating electrophysiological and behavioral assessments may facilitate early diagnosis and timely intervention to prevent irreversible auditory dysfunction.
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4. Improving Voice Outcomes After Transoral Laser Surgery for Early Glottic Cancer: A Systematic Review.
PMID:期刊:日期:2026-09-25To determine which intraoperative and postoperative interventions improve voice outcomes following transoral laser microsurgery (TLM) for early-stage glottic squamous cell carcinoma (T1-T2). English literature was searched on PubMed, OVID Medline, CINAHL, Embase, and Scopus. PRISMA guidelines were followed. Studies were excluded if patients received radiotherapy or non-TLM surgical approaches, had advanced-stage disease (>T2) or nonsquamous cell histology, had less than 5 participants, or were published in a non-English language. Commentaries, letters to the editor, literature reviews, and conference abstracts were also excluded. Two thousand and seventy-five articles were screened and 13 were included categorized into 4 domains: voice therapy (n = 2), injection augmentation (n = 2), intraoperative surgical modifications (n = 5), and postoperative reconstruction (n = 4). Voice therapy demonstrated significant benefit over controls in an RCT (VHI-30: -31.5 vs +3.35 points, P < .01). Modified Type III cordectomy preserving the inferior vocalis muscle achieved voice outcomes comparable to Type I/II resections with 85% complete glottic closure versus 33% with classical resection (P = .026). Injection augmentation showed no benefit for contralateral hyaluronic acid (RCT) and mixed results for ipsilateral autologous fat. Reconstruction procedures demonstrated postoperative improvements in select individuals but lacked standardized implant materials and comparative controls. Voice rehabilitation following TLM remains understudied. Current evidence supports structured voice therapy as an effective intervention. Modified Type III cordectomy demonstrates benefit in select patients with favorable tumor location. Injection augmentation is not yet supported but highlights an area of future research. Future multi-center randomized trials with standardized outcomes are needed to distinguish intervention effectiveness.
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5. Association of Depression and Anxiety With Postoperative Complications After Septoplasty With Turbinoplasty.
PMID:期刊:日期:2026-09-25Evaluate the association between comorbid depression and anxiety and postoperative complications following septoplasty with turbinoplasty, and assess whether treatment of these conditions influences surgical outcomes. Retrospective cohort study with propensity-score matched analysis. Multi-institutional database study utilizing the TriNetX Research Network. The TriNetX Research Network was utilized to identify patients undergoing septoplasty and concurrent turbinoplasty; propensity score-matched analyses were conducted after adjusting for demographics and medical comorbidities. Postoperative complication rates for anosmia, epistaxis, opioid prescription, emergency department (ED) visits, sinusitis, readmission, and septal perforation were compared among patients without depression or anxiety, patients with untreated depression/anxiety, and patients with medication-treated depression/anxiety. Patients (n = 5012 per group) without depression or anxiety had lower odds of epistaxis (OR 0.70, P = .0083), sinusitis (OR 0.62, P = .0019), ED visits (OR 0.52, P < .0001), hospital readmission (OR 0.55, P < .0001), and postoperative opioid prescription (OR 0.77, P < .0001) than patients with depression/anxiety. Patients (n = 4470 per group) with untreated depression/anxiety had higher odds of epistaxis (OR 3.94, P < .0001) but a lower 90-day risk of hospital readmission (OR 0.38, P < .0001) and opioid prescription (OR 0.69, P < .0001) compared to treated depression/anxiety. Comorbid depression or anxiety are associated with differences in outcomes following septoplasty with turbinoplasty. Future studies are needed to clarify the impact of treating psychiatric disorders on postoperative outcomes following otolaryngology procedures.
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6. Diagnostic Performance of Vestibular-Evoked Myogenic Potentials for Acute Unilateral Vestibulopathy: A Systematic Review and Meta-analysis.
PMID:期刊:日期:2026-09-25The goal of this study is to evaluate the pooled diagnostic performance of cervical (cVEMP) and ocular (oVEMP) vestibular-evoked myogenic potentials for Acute Unilateral Vestibulopathy. MEDLINE, EMBASE, Scopus, and Cochrane Central were searched for relevant articles from inception to October 2025. We included prospective, retrospective, and cross-sectional studies evaluating the performance of cVEMP and oVEMP for the diagnosis of acute unilateral vestibulopathy in adult patients. The pooled estimates of the sensitivity and specificity of cVEMP and oVEMP in the diagnosis of acute unilateral vestibulopathy were calculated using a random-effects analysis that accounts for heterogeneity if present. Forest plots were constructed to combine the evidence identified during the systematic review. Forty-one studies were included; 15 contributed to diagnostic accuracy meta-analyses (519 patients, 577 controls). Pooled cVEMP sensitivity was 40% (95% CI, 0.30-0.50; I = 64.2%) and specificity 100% (95% CI, 0.00-1.00; I = 0%). Pooled oVEMP sensitivity was 74% (95% CI, 0.57-0.86; I = 55.9%) and specificity 99% (95% CI, 0.88-1.00; I = 0%). Abnormality rates were 40% for cVEMP (633/1540; I = 85.2%) and 67% for oVEMP (679/1135; I = 92.7%). Subgroup analyses revealed enhanced oVEMP sensitivity with air-conducted sound (76%) and tone-burst stimuli (82%), while cVEMP achieved superior sensitivity when elicited by bone-conducted vibration (49% vs 37% with air-conducted sound). VEMPs show high specificity but moderate sensitivity for diagnosing acute unilateral vestibulopathy, with oVEMP outperforming cVEMP because superior vestibular nerve involvement is more common. Therefore, VEMPs should be used as complementary rather than standalone tests alongside clinical and canal-based tests.
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7. Hormone Replacement Therapy and Recurrence Risk in Postmenopausal Idiopathic Subglottic Stenosis.
PMID:期刊:日期:2026-09-24To evaluate whether systemic hormone replacement therapy (HRT) influences recurrence outcomes in postmenopausal patients with idiopathic subglottic stenosis (iSGS). Retrospective cohort study. Tertiary academic medical center. Postmenopausal women (≥50 years) with iSGS who underwent laser-wedge excision between 2002 and 2024 were included. Patients were categorized by systemic HRT exposure (oral estrogen, progesterone, combined estrogen-progesterone, or transdermal estrogen) at or before their first surgery. Overdispersion was assessed for all Poisson models; given significant overdispersion, negative binomial regression with a log-offset for follow-up time was used as the primary model. Surgery-free intervals were analyzed using linear mixed models, and time to first recurrence using Cox regression. Models were adjusted for age, body mass index (BMI), parity, oophorectomy, follow-up length, surgery type, and serial intralesional steroid injections (SILSI) use. Among 125 patients, 96 had never used HRT (Never HRT) and 29 used HRT, including 19 actively using HRT at presentation (Current HRT), 5 past users, and 5 subsequent users. The HRT versus Never-HRT recurrence rate comparison was not significant (adjusted incidence rate ratio [IRR] = 0.81, 95% CI: 0.48-1.37, P = .422). However, Current HRT use was associated with a 53% lower adjusted recurrence rate versus Never-HRT use (adjusted IRR = 0.47, 95% CI: 0.25, 0.89, P = .0203). Surgery-free intervals and time to first recurrence trended longer in Current HRT users but were not statistically significant. Current HRT use at presentation was associated with significantly fewer recurrences in postmenopausal iSGS patients. These findings may inform individualized, shared decision-making regarding HRT use in this population. LEVEL OF EVIDENCE: 3
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8. Age-Related Interaction of Endolymphatic Hydrops and Hearing Loss in Meniere's Disease.
PMID:期刊:日期:2026-09-24To examine the associations among age, endolymphatic hydrops (EH), and hearing thresholds in patients with Meniere's disease (MD) confirmed by gadolinium-enhanced inner ear magnetic resonance imaging (MRI), and to explore age-dependent effects of EH on hearing loss. Retrospective study. Tertiary medical center. We included 455 patients (910 ears) diagnosed with MD between January 2020 and April 2025. EH was graded using established vestibular and cochlear hydrops classification systems on Gd-enhanced inner ear MRI. Hearing thresholds (0.125-8 kHz) were obtained by pure-tone audiometry. Multivariable ordinal logistic regression assessed associations between age and EH grade. Generalized additive models with a Gamma distribution and log link were applied to evaluate nonlinear interactions between age and EH severity across low-, mid-, and high-frequency ranges and four-frequency averages. Age distribution did not differ significantly across EH laterality, site, or grade, and age was not independently associated with EH severity. Both EH grade and age were significantly associated with hearing thresholds (P < .05). Higher EH grades were consistently correlated with greater hearing loss in both unilateral and bilateral MD. In contrast, the influence of age was most evident at lower EH grades (I-III) and diminished in higher grades (IV-V). Age was not significantly associated with the presence or severity of EH in patients with MD. Higher EH grades were consistently associated with greater hearing loss. At the same time, the effect of age was most evident in mild-to-moderate EH grades and diminished in advanced stages.
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9. Treatment Duration and Clinical Response Patterns of Laryngopharyngeal Reflux Disease.
PMID:期刊:日期:2026-09-24To investigate the therapeutic response patterns in terms of duration, resistance, and therapeutic failure in patients with a confirmed LPRD diagnosis. Prospective study. University hospital. Patients with laryngopharyngeal symptoms and >1 pharyngeal reflux event on 24-h hypopharyngeal-esophageal impedance-pH monitoring were prospectively recruited (European Reflux Clinic, Jan 2017-Oct 2025). Based on LPRD pattern, they received diet/lifestyle measures plus alginate, magaldrate and/or PPIs in successive 3-month courses until significant symptom relief allowed discontinuation. Outcomes (RSS, RSA) and optimal treatment duration, success/weaning rates, and chronicity were assessed. A total of 361 consecutive patients completed the evaluations (214 females, 59.3%), with 135 (37.4%), 87 (24.1%), and 139 (38.5%) presenting mild, moderate, and severe reflux disease (IFOS classification), respectively. Of 304 patients with complete follow-up, 105 (34.5%) achieved complete response, occurring primarily at 6 weeks (27.6%), 3 months (42.9%), and 6 months (21.9%) posttreatment; 93/105 (88.6%) remained symptom-free after discontinuation. Symptoms stabilized in 148/304 (48.7%) patients continuing diet and lifestyle modifications with/without medication. Fluctuating relief and chronic course occurred in 21/304 (6.9%) and 30/304 (9.9%) despite drug class changes. Binary logistic regression revealed baseline IFOS classification as a significant predictor of complete response (P = .038, OR = 1.518, 95% CI [1.024-2.251]). Several LPRD patterns were identified: 34.5% achieved complete remission, 48.7% showed sustained symptom reduction, and 16.8% had fluctuating/chronic symptoms despite drug class changes. Baseline IFOS score predicts therapeutic trajectory and outcomes.
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10. CT-Based Osteitis Severity for Identifying Eosinophilic Endotype in Chronic Rhinosinusitis With Nasal Polyps.
PMID:期刊:日期:2026-09-24To determine whether computed tomography-based osteitis severity reflects the eosinophilic endotype and to compare its discriminatory performance with conventional mucosal radiologic scoring. Prospective cohort study. A tertiary referral otolaryngology hospital in Ho Chi Minh City, Vietnam. A total of 154 patients with chronic rhinosinusitis with nasal polyps were prospectively included. Osteitis severity was assessed using the Kennedy Osteitis Score. Tissue eosinophil density was quantified histopathologically, and eosinophilic endotype was defined as ≥10 eosinophils per high-power field. Associations were analyzed using Spearman correlation and multivariable regression. Receiver operating characteristic analysis evaluated the ability of this score and Lund-Mackay score to identify eosinophilic disease. Osteitis severity correlated with tissue eosinophil density (r = 0.45, P < .001) and Lund-Mackay score (r = 0.42, P < .001). In multivariable analysis, tissue eosinophils (β = 0.31, P < .001) and Lund-Mackay score (β = 0.31, P < .001) remained independently associated with osteitis severity. Receiver Operating Characteristic analysis showed good discrimination of eosinophilic endotype by Kennedy Osteitis Score (AUC = 0.777), outperforming Lund-Mackay score (AUC = 0.661). A threshold ≥1 yielded 69.6% sensitivity and 83.3% specificity. Computed tomography-based osteitis severity reflects tissue eosinophilia and outperforms conventional mucosal radiologic scoring, supporting its potential as a noninvasive imaging marker for preoperative endotype stratification.