MEDICINA CLINICA临床医学
MEDICINA CLINICA(英文缩写 MED CLIN-BARCELONA),ISSN 0025-7753,eISSN 1578-8989,中文译名:临床医学 是一本学术期刊。本页汇总该期刊的最新影响因子、分区信息以及最新收录于 PubMed 的文献,帮助您快速了解期刊全貌。
发文量统计区间：2025-09-27 至 2026-09-27，按本站收录文献的发表日期统计。
期刊介绍
历年影响因子趋势
| JCR 数据年份 | 影响因子 | JCR 分区 |
|---|---|---|
| 2021 | 3.200 | Q2 |
| 2022 | 3.900 | Q2 |
| 2023 | 2.600 | Q1 |
| 2024 | 2.100 | Q2 |
| 2025 | 2.800 | Q1 |
MEDICINA CLINICA 最新收录文献
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1. Use of pembrolizumab in HIV-associated progressive multifocal leukoencephalopathy: A four-case series.
PMID:日期:2026-09-01该文献暂无摘要。
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2. Optimising the duration of antimicrobial treatment in the era of Antimicrobial Stewardship Programs.
PMID:日期:2026-09-01The duration of antimicrobial treatment for bacteremia has changed radically over the last decade, with shorter regimens now being the norm, the duration is now seven days in most cases. This change, which has brought countless clinical and ecological benefits, has been made possible by independent clinical research led by PROA teams in their tireless efforts to improve antimicrobial use and combat AMR. The evidence is so strong in Enterobacterales that it is now considered inappropriate to treat uncomplicated bacteraemia caused by Escherichia coli, for example, for more than seven days. In other cases of bacteremia caused by Gram-negative bacilli, Gram-positive cocci, and Candida spp., clinical trials are needed to establish the optimal duration of antimicrobial treatment with certainty.
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3. Reduced serum IL-6 as a potential peripheral marker of amnestic mild cognitive impairment: A pilot study.
PMID:日期:2026-09-01Mild cognitive impairment (MCI) represents an intermediate state between age-related cognitive changes and early stages of dementia. People with amnestic subtype (aMCI) show higher risks of progression to dementia due to Alzheimer's disease. In this pilot study, the aim was to investigate whether cytokines could be potential peripheral markers associated with MCI. Women were recruited in Junín city, Buenos Aires, Argentina. Their cognitive performance was evaluated using a neuropsychological battery. Serum levels of IFN-γ, IL-1β, IL-2, IL-4 and IL-6 were analyzed by ELISA, and the type 2/type 1 balance was determined. Correlations between both parameters, as well as within-group analysis cytokines levels were evaluated. After cognitive evaluation, participants were classified as healthy controls (HC: n=14) or as aMCI (n=7). IL-6 levels were significantly decreased in the aMCI group compared with HC (p=0.047). IFN-γ showed no robust correlations within the HC group but presented a strong negative correlation with IL-2 (p=0.005) and IL-4 (p=0.052) in aMCI. Several correlations were found between cytokine levels, the type 2/type 1 balance and neurocognitive tests. We concluded that IL-6 decreased levels, altered correlation in cytokine profiles, together with performance on the neuropsychological battery, may serve as potential blood-markers of amnestic mild cognitive impairment.
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5. Subacute intermittent purpura: A cutaneous manifestation of cryoglobulinemic vasculitis.
PMID:日期:2026-09-01该文献暂无摘要。
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7. Tobacco-related and tobacco-attributable cancer mortality in Spain, 1999-2023: trends and gender inequalities.
PMID:日期:2026-09-01Tobacco is the leading risk factor for multiple cancers. Changes in smoking patterns make it essential to assess trends in mortality from tobacco-related cancers in Spain between 1999 and 2023, by sex, age and autonomous community, as well as to estimate tobacco-attributable cancer mortality in individuals aged ≥35years and explore gender inequalities. Deaths from cancers strongly associated with tobacco use (ICD-10: C00-15; C32-34; C67) were analyzed for the period 1999-2023. Age-adjusted mortality rates were calculated and trends were assessed using joinpoint regression models. Tobacco-attributable mortality was estimated by combining smoking prevalence, relative risks for current and former smokers, and the number of deaths, obtaining population attributable fractions in individuals aged ≥35years. Between 1999 and 2023, mortality decreased among men for all studied cancers (-27.9% for lung cancer; -56.4% for laryngeal cancer). In women, mortality increased for lung cancer (+104.1%), lip-oral cavity-pharynx cancer (+30.0%) and laryngeal cancer (+16.3%), with the greatest increase observed among women aged 55-69years (+219.1% in lung cancer). Across autonomous communities, men showed widespread declines, whereas increases were observed in most regions among women. Between 2000 and 2023, tobacco use caused more than 600,000 cancer deaths (two-thirds due to lung cancer). Mortality from tobacco-related cancers shows divergent trends by sex, highlighting the need to strengthen tobacco control and prevention policies with a gender perspective, and to continue monitoring smoking patterns and related mortality.
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8. Prevalence and determinants of long COVID and SARS-CoV-2 reinfection in the Spanish adult population: A nationwide public health survey.
PMID:日期:2026-09-01Long COVID is an emerging public health concern with heterogeneous prevalence. Evidence on the impact of reinfection and vaccination remains limited, especially in Spain. We conducted a prospective online cohort survey between January 2024 and April 2025, gathering data on demographics, vaccination, symptoms, comorbidities, and reinfection history from Spanish adults (n=1018). Long COVID was defined per NICE guidelines as symptoms persisting beyond eight weeks after viral clearance. Multivariate logistic regression identified associated factors. Of 972 participants (332 men, 640 women), long COVID prevalence was 14.3% (n=139). Female sex (OR: 1.70; 95% CI: 1.10-2.57; p=0.014) and chronic obstructive pulmonary disease (COPD) (OR: 4.14; 95% CI: 1.28-13.42; p=0.018) increased risk. Mixed vaccination schedules raised risk compared to Pfizer-only regimens (OR: 1.30; 95% CI: 1.04-1.62; p=0.020). Reinfection, reported by 47.2%, was also a risk factor (OR: 1.64; 95% CI: 1.12-2.42; p=0.012). Frequent long COVID symptoms included anosmia, dyspnea, pneumonia, and myalgia. This national cohort underscores the persistent burden of long COVID in Spain. Female sex, COPD, reinfection, and mixed vaccination schedules are key associated factors, with implications for targeted prevention strategies and vaccination policies.
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9. Impact of diagnostic delay in COVID-19 index cases on SARS-CoV-2 transmission to household contacts.
PMID:日期:2026-09-01Diagnostic delay in COVID-19 index cases may increase household transmission of SARS-CoV-2. A prospective epidemiological study was conducted to analyze SARS-CoV-2 infection among household contacts of confirmed COVID-19 cases. Recruitment of index cases and their household contacts took place in eight primary care centers. This study included 227 index cases and 329 household contacts and examined the association between the time from symptom onset to index case diagnosis and the household transmission rate of SARS-CoV-2. The prevalence of infection among contacts was 38.9%, increasing with age and reaching 60.6% among individuals aged 65 years or older. Diagnostic delays longer than two days were associated with a higher risk of infection: contacts exposed to index cases diagnosed with a 3-4-day delay had twice the risk compared with those diagnosed earlier (adjusted odds ratio, aOR=2.1; 95% CI: 1.1-3.7). Older age was confirmed as a risk factor (aOR=6.0; 95% CI: 2.3-15.7), while previous SARS-CoV-2 infection and vaccination of the index case were identified as protective factors (aOR=0.5; 95% CI: 0.3-0.9 and 0.3; 95% CI: 0.1-0.6, respectively). These findings demonstrate that diagnostic delay significantly increases household virus transmission, particularly among older adults, highlighting the need to strengthen early detection mechanisms and ensure rapid access to diagnostic testing in all settings.
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10. Iron-deficiency anemia secondary to autoimmune gastritis and celiac disease.
PMID:日期:2026-09-01该文献暂无摘要。