BIOPOLYMERS生物聚合物
BIOPOLYMERS(英文缩写 BIOPOLYMERS),ISSN 0006-3525,eISSN 1097-0282,中文译名:生物聚合物 是一本学术期刊。本页汇总该期刊的最新影响因子、分区信息以及最新收录于 PubMed 的文献,帮助您快速了解期刊全貌。
发文量统计区间：2025-11-01 至 2026-10-31，按本站收录文献的发表日期统计。
期刊介绍
历年影响因子趋势
| JCR 数据年份 | 影响因子 | JCR 分区 |
|---|---|---|
| 2021 | 2.240 | Q3 |
| 2022 | 2.900 | Q3 |
| 2023 | 3.200 | Q2 |
| 2024 | 3.200 | Q2 |
| 2025 | 2.900 | Q2 |
BIOPOLYMERS 最新收录文献
-
1. Molecular Interactions Between Bacteriorhodopsin Protein Embedded Within Purple Membrane and the Surfaces of Polyvinyl Alcohol (PVA) and Graphene.
1. 嵌入紫膜中的细菌视紫红质蛋白与聚乙烯醇（PVA）和石墨烯表面之间的分子相互作用PMID:日期:2026-09-18Bacteriorhodopsin (bR), the light-driven proton pump of Halobacterium salinarum, is a promising candidate for bioelectronic and optoelectronic applications. Its utility in hybrid systems depends on how surrounding materials influence structural stability and photocycle dynamics. In this work, all-atom molecular dynamics simulations are conducted under isothermal-isobaric conditions to evaluate bR in three environments: its native purple membrane, adsorption onto graphene sheets, and incorporation within a polyvinyl alcohol (PVA) matrix. Across all systems, bR displayed preferential adsorption on the extracellular side of the membrane. Graphene promoted strong and stable interactions, preserving native electrostatic contacts, enhancing Van der Waals forces, and allowing conformational flexibility essential for photocycle transitions. In contrast, PVA generated weaker stabilization, a water-rich interface, and disruption of key electrostatic interactions, which constrained protein adaptability. These findings identify graphene as a favorable surface for maintaining both structural integrity and functional dynamics of bR, supporting its integration within PVA based scaffolds toward the development of bio-nano interfaces.
-
2. Pre-Esterification Dry Heat Treatment Enhances the Functional Properties of Starch Citrate: Enzyme Resistance and Water Absorption.
2. 酯化前干热处理增强柠檬酸淀粉的功能特性：酶抗性和吸水性PMID:日期:2026-09This study investigates how pre-esterification dry heat treatment (DHT) of corn starch at 170°C, 180°C, and 200°C influences the functional properties of subsequently synthesized starch citrates. Structural and morphological changes induced by DHT and esterification were analyzed using scanning electron microscopy, X-ray diffractometry, and Fourier-Transform Infrared spectroscopy. Starch citrates were characterized for their resistance to pancreatic α-amylase and amyloglucosidase, as well as their water absorption capacity (WAC) at 37°C. Results demonstrated a strong correlation between DHT temperature and the functional properties of the final citrate. Increasing the DHT temperature significantly increased the resistant starch fraction and WAC. Specifically, citrates from native starch had a resistant starch (RS) fraction of 91%, while citrates from starch pre-treated at 200°C exhibited a markedly increased RS fraction of 98% and a 64% increase in WAC. These findings indicate that DHT is an effective pre-treatment for enhancing the dietary fiber potential and hydration properties of starch citrates.
-
3. Biogenic Silver Nanoparticles-Loaded Collagen-L-Lysine Matrices in Gel and Spray Formulations for Improved Skin Wound Repair.
PMID:日期:2026-09Biogenic silver nanoparticles (AgNPs) are emerging as valuable candidates in biomedical research, offering advantages such as cost-effectiveness, eco-friendly preparation methods, and superior biocompatibility. Owing to the challenges in the treatment of chronic skin injury, this study utilizes biogenic AgNPs (synthesized using Shilajit as a reducing and stabilizing agent) to develop gel and spray formulations (constituting fish collagen and l-lysine) for wound-healing applications. FTIR analysis indicated the involvement of functional groups from the Shilajit extract in synthesizing crystalline spherical AgNPs of 140-160 nm diameter. EDAX analysis reported 0.6% (by weight) silver in both formulations, with major elemental peaks for nitrogen, carbon, and oxygen, indicating the presence of polysaccharides. The MTT assay on HDFa cells confirmed that both preparations were nontoxic, as validated by FDA staining, which signified intact cell morphology. In vivo findings demonstrated that ShilAgNPs-Fcol-Lys formulations promote rapid wound closure, effective extracellular matrix (ECM) deposition, advanced neovascularization, and improved tissue remodeling compared with controls and standard treatments. Well-organized collagen deposition and efficient remodeling were confirmed by histology and immunohistochemistry, with the spray formulation performing better than the gel. Thus, ShilAgNPs-Fcol-Lys formulations offer a biocompatible, safe, and cost-effective alternative for treating deep excisional wounds.
-
4. Bacterial Cellulose Membranes for Dye Removal: Adsorption Behavior, Thermodynamics, Regeneration, and Performance in Simulated Wastewater.
PMID:日期:2026-09Bacterial cellulose is a sustainable biopolymeric material with considerable potential for wastewater treatment due to its nanofibrous structure and abundance of hydroxyl groups. In this study, BC membranes were evaluated as adsorbents for organic dyes, focusing on pH effects, adsorption behavior, and reusability. Adsorption performance was influenced by pH, with significant differences among some conditions; pH 7 was selected for subsequent experiments based on adsorption performance and its practical relevance. Kinetic studies showed rapid initial adsorption followed by a slower approach to equilibrium, while the maximum experimental adsorption capacity for methylene blue (MB) reached 100.15 mg g. BC membranes were separately evaluated with MB, crystal violet, and methyl orange in the presence of inorganic salts, showing effective but dye-dependent removal. Reusability tests showed a progressive decline, with a 37.26% loss after five adsorption-desorption cycles. FTIR analysis indicated preservation of the main structural features of BC after adsorption. Hydrogen bonding and electrostatic interactions are proposed as plausible contributors to adsorption. Overall, BC membranes showed promising adsorption performance, although regeneration requires further optimization.
-
5. High-Efficiency Carboxymethylation Achieved by Enhancing Hydroxyl Accessibility Through Glycerol Pretreatment of Bacterial Cellulose.
PMID:日期:2026-08-31Due to its dense crystalline structure and extensive hydrogen bonding network, cellulose exhibits limited reactive accessibility and reactivity, which severely restricts the reaction efficiency, degree of substitution, and uniformity of cellulose modifications such as carboxymethylation. To overcome these limitations, this study developed a novel glycerol-based pretreatment strategy to disrupt the hydrogen bonding network of bacterial cellulose (BC), thereby improving its reactive accessibility. The results confirmed that glycerol pretreatment significantly enhanced the reactivity of BC. The reaction time for preparing carboxymethyl cellulose (CMC) from glycerol-pretreated powdered BC was reduced from 2 to 1 h, representing a 100% improvement in reaction efficiency. In addition, glycerol pretreatment facilitated the exposure of hydroxyl groups in BC, thereby increasing the degree of substitution of CMC from 0.297 to 0.433 and from 0.427 to a peak value of 0.626, an approximately 46% enhancement. In addition, the CMC films prepared from glycerol-pretreated BC exhibited significantly improved light transmittance, reaching over 95% in the wavelength range of 300-1000 nm. This study provides theoretical support and technical guidance for the efficient production of CMC, expands its application potential in high-end fields, and promotes the high-value utilization of cellulose resources.
-
6. Unraveling the Asymmetric Hydration Dynamics and Water-Mediated Stabilization in Collagen Heterotrimers.
PMID:日期:2026-08-31Collagen's triple helix structure is fundamental to the mechanical integrity of bodily tissues, and its stability is vital for optimal physiological function. While the stabilization mechanisms of simple, symmetric collagen homotrimers have been previously studied, the hydration dynamics of native-like collagen heterotrimers which comprise the vast majority of human collagens remain largely unexplored. In this study, we investigated the complex role of water in stabilizing heterotrimeric collagen model peptides (CMPs) using extensive molecular dynamics (MD) simulations. We examined structurally diverse AAB-type and ABC-type heterotrimers exhibiting varying experimental stability profiles to investigate how sequence asymmetry influences hydration organization and collagen stability. Our simulations revealed that water molecules dynamically organize around these complex structures, forming topological water networks (TWNs) via intermolecular hydrogen bonds. Quantitative analyses of peptide-water interactions, hydration-water dynamics, and normalized TWN counts, together with residue- and chain-resolved TWN characterization, demonstrated that hydration-shell organization is strongly sequence dependent and differs among heterotrimers with distinct thermal stabilities. In particular, the more thermally stable heterotrimers exhibited a greater propensity for hydration-shell water molecules to participate in cyclic TWNs, accompanied by reduced hydration-water mobility and favorable interchain hydrogen-bonding interactions. These findings extend our previous observations on collagen homotrimers and provide new atomistic insight into the sequence-dependent organization of hydration water surrounding collagen heterotrimers, suggesting that organized hydration water contributes to collagen stability in concert with interchain hydrogen bonding and hydration-water dynamics rather than acting as an independent stabilization mechanism.
-
7. Inherent α-Helix Around Tyrosine 183 in the Intrinsically Disordered Tail of the Multi-Site Docking Platform Gab1.
7. 多位点对接平台Gab1内在无序尾部中酪氨酸183周围固有的α-螺旋PMID:日期:2026-08-04The biological function of intrinsically disordered proteins is frequently coupled to short linear motifs, which serve as protein binding sites. This goes often hand in hand with local transient structural element formation. The intrinsically disordered C-terminal region of the multi-site docking protein Grb2-associated binder 1 (Gab1) contains several well-characterized phosphotyrosine pairs, whereas the Tyr162 and Tyr183 epitopes have remained practically unstudied. Here, we combine computational prediction, circular dichroism and high-resolution NMR spectroscopy (chemical shift and relaxation analyses) to structurally characterize a Gab1 fragment containing residues 142-203. The here determined NMR structure shows an α-helix for residues Pro180 to Ile187, with Tyr183 positioned centrally, while all other parts of the fragment, including the region around Tyr162, are disordered. This helical conformation is maintained upon changes in pH, variation of peptide lengths and phosphorylation status. The inherent helix around Tyr183 distinguishes the local structural environment of Tyr162 and Tyr183 within the intrinsically disordered Gab1 tail and provides a structural framework for future studies on interaction partners and potential functional roles of this structural motif.
-
8. Role of Water in Starch Mechanical Treatment.
8. 水在淀粉机械处理中的作用PMID:日期:2026-07-21The impact of initial moisture content (1.5%-20%) on the ball-milling of pea starch was investigated across multiple structural levels. Scanning electron microscopy revealed moisture-dependent deformation mechanisms: plastic flow and agglomeration in high-moisture granules versus pseudo-brittle fracture in low-moisture samples. Despite these differences, XRD-detectable crystallinity was eliminated within 5 min of treatment, independent of initial moisture content. Fourier transform infrared spectroscopy confirmed the loss of short-range molecular order, including helical and hydrogen-bonded contributions. Gel permeation chromatography demonstrated more severe molecular degradation in low-moisture starch, suggesting a possible two-stage degradation behavior, with a rapid initial decrease of molar mass followed by a slower regime as the material becomes predominantly amorphous. Consequently, ball-milling enhanced solubility in both cold (30°C) and hot (90°C) water, increasing it from less than 1% and ~25% to 60%-70%, respectively. The increased cold-water solubility is explained by the loss of crystallinity. In contrast, the rise in hot-water solubility indicates a more profound structural disintegration. We propose that this is related to the mechanochemical degradation of amylopectin, which may suppress the formation of amylopectin-rich remnants during gelatinization and thereby promote dissolution.
-
9. Fluorescent Leaf-Like Structures Formed by Self-Assembly of Green Fluorescent Protein.
9. 由绿色荧光蛋白自组装形成的荧光叶状结构PMID:日期:2026-07-21Green fluorescent protein (GFP) was originally obtained from Aequorea victoria and was successfully synthesized through recombinant technology. In this study, we revealed novel, fascinating insights into the properties of this well-known GFP by examining a traditional GFP separation process involving aqueous two-phase systems and several liquid chromatographs. We investigated the impact of organic solvents and salts on the conformation of GFP by measuring its fluorescence intensity and circular dichroism spectrum, and then proposed an optimized process to improve the yield of fluorescent GFP. We have noticed that fluorescent GFP migrates anomalously to ~37 kDa on non-heating SDS-PAGE due to retention of its compact β-barrel conformation, whereas the commonly reported 27 kDa migration corresponds to the fully heat-denatured, non-fluorescent form. Nevertheless, the most exciting discovery is that the purified GFP exhibited a remarkable ability to self-assemble into an intriguing fluorescent leaf-like structure upon evaporation-concentration under ambient conditions. To our knowledge, this represents the first direct visualization of such macroscopic fluorescent leaf-like assemblies formed by recombinant GFP, with fluorescence retained throughout the assembled morphology. This captivating phenomenon may have promising implications for protein-based nanomaterials and will inspire further exploration of protein self-assembly nanotechnology.
-
10. Zeolite-Reinforced PVA/Chitosan/Hyaluronic Acid Composite Films as Biocompatible Tissue Patches.
10. 沸石增强的PVA/壳聚糖/透明质酸复合薄膜作为生物相容性组织补片PMID:日期:2026-07-16Tissue patches are biomaterial-based structures designed to support the repair of damaged or functionally impaired tissues and are required to exhibit biocompatibility, mechanical integrity, and suitable surface characteristics. In this study, poly(vinyl alcohol) (PVA), chitosan (Chi), and hyaluronic acid (HA)-based composite films reinforced with zeolite (0-0.5% w/v) were developed and evaluated as potential tissue patch materials. The incorporation of zeolite significantly influenced the physicochemical and mechanical properties of the films. The elastic modulus decreased from 293.78 ± 64.47 N/mm for the zeolite-free film to 106.21 ± 9.50 N/mm at the highest zeolite content, indicating tunable flexibility. Water contact angle values increased from 46.09° to 67.23°, while maintaining overall hydrophilicity. The films exhibited rapid swelling behavior, reaching equilibrium within 30 min, and demonstrated controlled biodegradation with mass losses exceeding 75% after 42 days. Biological evaluations showed that all formulations maintained cell viability above 70%, with values ranging from 87.26% to 78.63%, and supported cell adhesion, confirming their biocompatible nature. The novelty of this study lies in demonstrating that low-concentration zeolite incorporation enables controlled tuning of mechanical, surface, and biological properties within a single PVA-Chi-HA system, without compromising biocompatibility. These findings highlight the potential of zeolite-reinforced composite films as multifunctional and customizable tissue patch candidates for tissue engineering applications.