回到基础：每日盐水湿敷是复发性儿童劈裂厚度皮肤移植失败的转折点
Back to Basics: Daily Saline Wet Dressings as a Turning Point in Recurrent Pediatric Split-Thickness Skin Graft Failure.
摘要(中文译文)
分层皮片移植（split-thickness skin grafting，STSG）是处理创伤性软组织缺损的常用重建技术。移植皮片的成功成活取决于充分的创面床准备和有效的感染控制。多重耐药菌感染仍是移植失败的主要原因，尤其是在复杂的儿童创伤病例中。我们报告一例既往健康的12岁男性，表现为双侧大腿软组织缺损，合并多重耐药菌感染和反复移植失败。尽管接受了多次手术清创、针对性抗生素治疗和负压创面治疗，仍出现持续性移植皮片坏死。随后对术后创面护理进行了调整，包括更早更换敷料及每日使用生理盐水湿敷。该方法使移植皮片成功成活并实现创面完全愈合，凸显了简单、低成本创面护理策略在改善复杂感染创面结局中的潜在作用。本病例强调了基础创面护理原则在复杂感染创面管理中的重要性。早期且频繁的创面评估，结合生理盐水敷料，可能对实现移植成功发挥关键作用，即使在多重耐药菌感染的情况下亦然。
Abstract
Split-thickness skin grafting (STSG) is a widely used reconstructive technique for managing traumatic soft tissue defects. Successful graft take depends on adequate wound bed preparation and effective infection control. Multidrug-resistant infections remain a major cause of graft failure, particularly in complex pediatric trauma cases. We report the case of a 12-year-old previously healthy male presenting with bilateral thigh soft tissue defects complicated by multidrug-resistant infections and repeated graft failure. Persistent graft necrosis occurred despite multiple surgical debridements, targeted antibiotic therapy, and negative pressure wound therapy. A modification in postoperative wound care was implemented, including earlier dressing changes and the use of daily saline wet dressings. This approach resulted in successful graft take and complete wound healing, emphasizing the potential role of simple, low-cost wound care strategies in improving outcomes in complex infected wounds. This case underscores the importance of fundamental wound care principles in the management of complex infected wounds. Early and frequent wound assessment, combined with saline-based dressings, may play a critical role in achieving graft success, even in the setting of multidrug-resistant infections.
如何引用
AMA
Jana H Mahdi, Elie Moukawam, Ziad R Hankach, George Ghanime, Ziad Sleiman. Back to Basics: Daily Saline Wet Dressings as a Turning Point in Recurrent Pediatric Split-Thickness Skin Graft Failure.. Cureus. 2026; doi:10.7759/cureus.108464.
APA
Jana H Mahdi, Elie Moukawam, Ziad R Hankach, George Ghanime, Ziad Sleiman (2026). Back to Basics: Daily Saline Wet Dressings as a Turning Point in Recurrent Pediatric Split-Thickness Skin Graft Failure.. Cureus. https://doi.org/10.7759/cureus.108464
GB/T 7714
Jana H Mahdi, Elie Moukawam, Ziad R Hankach, George Ghanime, Ziad Sleiman. Back to Basics: Daily Saline Wet Dressings as a Turning Point in Recurrent Pediatric Split-Thickness Skin Graft Failure.[J]. Cureus, 2026 doi:10.7759/cureus.108464.
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