从姜味白酒酒糟中提取的酵母培养物可以增强鹅的免疫功能和肠道健康
Yeast culture derived from Jiang-flavor Baijiu distiller's grains enhances immune function and gut health in geese.
摘要(中文译文)
本研究评估了饲粮中添加酱香型白酒酒糟酵母培养物（JBGC）对鹅免疫性能和肠道健康的影响。选取512只1日龄马冈鹅，随机分为4个饲粮处理组：0%（对照组）、2%、6%或10% JBGC，每处理8个重复，每重复16只鹅，试验期70天。JBGC添加对抗氧化和炎症反应呈现剂量和时间依赖性效应。与对照组相比，10% JBGC显著降低了第70天血清谷胱甘肽过氧化物酶活性和第28天总抗氧化能力（< 0.05），而6%和10% JBGC均提高了肝脏总超氧化物歧化酶活性（< 0.05）。在炎症标志物方面，10% JBGC降低了第70天血清IL-1β水平（< 0.05），且所有JBGC添加组（2%、6%和10%）在后期阶段IL-8水平均显著低于对照组（< 0.05）。此外，6%和10% JBGC提高了第70天抗炎细胞因子IL-10水平（< 0.05）。JBGC还改善了肠道形态和屏障功能：6%和10% JBGC增加了回肠绒毛高度（< 0.05）；10% JBGC提高了十二指肠长度和重量、空肠重量及小肠总重量；6% JBGC上调了occludin和claudin-5的蛋白表达（< 0.05）。尽管盲肠微生物α多样性无显著差异，但若干有益菌属呈现增加趋势。这些结果表明，JBGC可通过影响抗氧化状态、炎性细胞因子谱、肠道形态和屏障完整性，对鹅的免疫和肠道健康产生正向调节作用。
Abstract
This study evaluated the effects of dietary supplementation with Jiang-flavor Baijiu distiller's grains yeast culture (JBGC) on immune performance and intestinal health in geese. A total of 512 one-day-old Magang geese were randomly assigned to four dietary treatments 0% (control), 2%, 6%, or 10% JBGC with eight replicates per treatment and 16 birds per replicate, over a 70-day experimental period. JBGC supplementation exhibited dose- and time-dependent effects on antioxidant and inflammatory responses. Compared with the control, 10% JBGC significantly reduced serum glutathione peroxidase activity at day 70 and total antioxidant capacity at day 28 ( < 0.05), whereas both 6% and 10% JBGC increased hepatic total superoxide dismutase activity ( < 0.05). Regarding inflammatory markers, 10% JBGC lowered serum IL-1β at day 70 ( < 0.05), and all JBGC-supplemented groups (2%, 6%, and 10%) showed significantly lower IL-8 levels than the control during the later phase ( < 0.05). Additionally, 6 and 10% JBGC elevated the anti-inflammatory cytokine IL-10 at day 70 ( < 0.05). JBGC also improved intestinal morphology and barrier function: 6 and 10% JBGC increased ileal villus height ( < 0.05); 10% JBGC enhanced duodenal length and weight, jejunal weight, and total small intestinal weight; and 6% JBGC upregulated the protein expression of occludin and claudin?5 ( < 0.05). Although cecal microbial alpha diversity did not differ significantly, several beneficial bacterial genera showed increasing trends. These findings indicate that JBGC can positively modulate immune and intestinal health in geese by influencing antioxidant status, inflammatory cytokine profiles, intestinal morphology, and barrier integrity.
如何引用
AMA
Pan Tao, Fei Zhang, Yu-Jie Li, Xiao-Jie Chen, Yi-Ming Zuo, Zhen-Hong Peng, et al. Yeast culture derived from Jiang-flavor Baijiu distiller's grains enhances immune function and gut health in geese.. Frontiers in veterinary science. 2026; doi:10.3389/fvets.2026.1846477.
APA
Pan Tao, Fei Zhang, Yu-Jie Li, Xiao-Jie Chen, Yi-Ming Zuo, Zhen-Hong Peng, et al (2026). Yeast culture derived from Jiang-flavor Baijiu distiller's grains enhances immune function and gut health in geese.. Frontiers in veterinary science. https://doi.org/10.3389/fvets.2026.1846477
GB/T 7714
Pan Tao, Fei Zhang, Yu-Jie Li, Xiao-Jie Chen, Yi-Ming Zuo, Zhen-Hong Peng, et al. Yeast culture derived from Jiang-flavor Baijiu distiller's grains enhances immune function and gut health in geese.[J]. Frontiers in veterinary science, 2026 doi:10.3389/fvets.2026.1846477.
在 PubMed增强版 阅读全文
翻译全文 · AI 文献问答 · PDF 原文下载 · 引用导出