Advances in Nutrition营养学进展
Advances in Nutrition(英文缩写 ADV NUTR),ISSN 2161-8313,eISSN 2156-5376,中文译名:营养学进展 是一本学术期刊。本页汇总该期刊的最新影响因子、分区信息以及最新收录于 PubMed 的文献,帮助您快速了解期刊全貌。
发文量统计区间：2025-11-01 至 2026-10-31，按本站收录文献的发表日期统计。
期刊介绍
历年影响因子趋势
| JCR 数据年份 | 影响因子 | JCR 分区 |
|---|---|---|
| 2021 | 11.567 | Q1 |
| 2022 | 9.300 | Q1 |
| 2023 | 8.000 | Q1 |
| 2024 | 9.200 | Q1 |
| 2025 | 12.700 | Q1 |
Advances in Nutrition 最新收录文献
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1. Toward International Dietary Guidance: A Food Guide Pyramid for Human and Planetary Health.
1. 迈向国际膳食指南：促进人类与地球健康的食物指南金字塔PMID:日期:2026-09-23Dietary guidelines shape food policy, education, and food systems worldwide. Recent controversies in dietary guideline development, together with rising burdens of diet-related chronic disease and increasing environmental pressures, highlight the need for globally relevant dietary guidance aligned with both human and planetary health. We developed an evidence-informed International Food Guide Pyramid emphasizing optimal carbohydrate-containing staple foods. The International Carbohydrate Quality Consortium (ICQC) developed the proposed framework using a four-step evidence-review process involving comparison of major national and regional dietary guideline systems, integration of evidence syntheses and selected primary studies, and expert consensus. Quantitative intake ranges from the EAT-Lancet Commission reference diet informed the relative visual proportions of food groups, while the guiding principles were derived from convergence across dietary guideline systems and complementary evidence syntheses. The resulting pyramid depicts a plant-forward omnivorous dietary pattern supported by epidemiological and clinical evidence indicating benefits for cardiometabolic health and chronic disease prevention. Vegetables, fruits, whole grains, and legumes constitute foundational components of the pyramid. Nuts, seeds, and unsaturated plant oils are emphasized as primary fat sources, while foods high in saturated fat are generally limited. Animal-source foods are included in modest amounts, with plant protein sources emphasized, poultry and fish preferred over red meat, and dairy incorporated in modest amounts, consistent with dietary patterns associated with lower environmental impacts. Carbohydrate quality is emphasized through prioritization of whole-grain foods alongside traditional low-glycemic index grain staples, favoring carbohydrate sources rich in dietary fiber, intact plant cells, and micronutrients while limiting sugars consumed in low-nutrient forms, particularly sugar-sweetened beverages. The framework also accommodates vegan and other primarily plant-based dietary patterns. This evidence-informed International Food Guide Pyramid integrates quantitative modeling and qualitative evidence synthesis to provide a coherent, flexible, and globally adaptable dietary framework aligned with both human and planetary health. STATEMENT OF SIGNIFICANCE: This work presents an evidence-informed International Food Guide Pyramid developed through a structured synthesis of major national and regional dietary guideline systems, quantitative modeling from the EAT-Lancet Commission, and complementary evidence syntheses. By translating areas of convergence across these independent evidence-based sources into a practical visual framework, it provides a globally adaptable approach to dietary guidance that explicitly incorporates carbohydrate quality and both human and planetary health.
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2. The Incretin Mirage: Epigenetic Memory as a Potential Driver of Post-Treatment Weight Regain.
PMID:日期:2026-09-17While incretin receptor agonists deliver profound weight loss, clinical data reveal a consistent challenge: treatment discontinuation routinely triggers rapid weight regain. We define this phenomenon as the "Incretin Mirage"-a state where pharmacologically induced weight reduction temporarily conceals the persistent metabolic and neuroendocrine adaptations established during chronic obesity. Despite a lower body mass, key drivers of the disease, including adipocyte dysfunction and altered appetite signaling, retain a molecular imprint of obesity driven by persistent epigenetic marks. To explain why the body aggressively resists sustained weight loss after treatment cessation, we introduce the "Epigenetic Detent." This novel conceptual mechanism links adipocyte epigenetic memory with neuroendocrine plasticity to preserve a high-adiposity set-point. Consequently, the moment pharmacological suppression is lifted, this persistently defended set-point serves as a potential driver of weight regain. Achieving a durable therapeutic response therefore requires moving beyond transient appetite suppression. We advocate for a coordinated, multi-tiered strategy that couples lifestyle and environmental restructuring with next-generation epigenetic therapies capable of erasing these cellular marks and achieving a complete cellular metabolic reset.
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3. Nutrition care and Dietetic Practice in Managing Metabolic and Endocrine Dysfunction in Polyendocrine Metabolic Ovarian Syndrome (PMOS): Implications and Opportunities in the Context of the Name Change of Polycystic Ovarian Syndrome (PCOS) to PMOS.
3. 多内分泌代谢性卵巢综合征（PMOS）中代谢与内分泌功能障碍管理中的营养照护与饮食实践：多囊卵巢综合征（PCOS）更名为PMOS背景下的影响与机遇PMID:日期:2026-09-16Polyendocrine metabolic ovarian syndrome (PMOS) affects 8-13% of women across the lifespan. Those with PMOS have reduced quality of life and increased risk of co-morbidities including elevated weight, eating disorders, gestational diabetes, type 2 diabetes and cardiovascular disease. PMOS is a major population in clinical dietetic practice and dietary intervention is the first-line approach recommended to target metabolic risk in the international evidence-based guidelines for assessment and management of PCOS. The past name, polycystic ovary syndrome (PCOS) was ovarian-centric and did not accurately reflect the pathophysiology, endocrine or metabolic dysfunction of the syndrome. The new name PMOS has been determined by a rigorous global consensus process including 56 organizations, >14,000 survey responses and consultation with experts and patients in workshops that identified the need for accurate medical representation of the syndrome and a stigma-reducing name. Dietitians encounter PMOS patients with increased cardiometabolic risk that also experience high rates of elevated weight, weight-stigma and eating disorders. Nutrition care of PMOS patients often involves managing these conditions, use of anti-obesity and diabetes medications, conferring with prescribing clinicians and navigating patient goals and preferences. Improved recognition of the metabolic risks can strengthen alignment with dietary management approaches and referral to nutrition care services as part of the multidisciplinary care needed in those with PMOS. Dietitians can play a key role in managing nutritional misinformation, supporting patient health literacy and nutritional self-management. The new name can contribute to expanded opportunities for nutritional research that targets endocrine and metabolic outcomes to improve the clinical care, health and well-being of those living with PMOS. STATEMENT OF SIGNIFICANCE: Polyendocrine metabolic ovarian syndrome (PMOS) is the new name for polycystic ovary syndrome. This perspective article highlights the rationale for the name change related to endocrine features and metabolic risk and the role nutritional management and dietetic practice, highlighting recent updates on dietary approaches, body weight, anti-obesity medications and eating disorders in PMOS.
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5. Letter to the Editor: Climate Change, Food Insecurity, and Pediatric Health: A Developmental Perspective.
5. 致编辑的信：气候变化、粮食不安全与儿科健康：发展的视角PMID:日期:2026-09-15该文献暂无摘要。
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6. Perspectives on the Nutritional Paradox in Uremia: A "Sensitize-Then-Feed" Framework for Protein-Energy Wasting.
6. 尿毒症中营养悖论的视角：蛋白质-能量消耗的“先增敏后喂养”框架PMID:日期:2026-09-09Protein-energy wasting (PEW) drives significant morbidity and mortality in advanced chronic kidney disease (CKD). Despite the implementation of comprehensive clinical guidelines and medical nutrition therapy, a subset of uremic patients may exhibit a defining "nutritional paradox." Unlike simple starvation, which responds to caloric and protein supplementation, CKD-associated cachexia is characterized by a potential systemic anabolic resistance. This renders standard nutritional interventions-including oral supplements and intradialytic parenteral nutrition-often insufficient. To elucidate the molecular hierarchy driving this barrier to nutritional therapy, we propose a model in which, during central dysregulation, gut-microbiome-derived uremic toxins, notably tryptophan metabolites, such as indoxyl sulfate, have been shown in experimental models to impair the blood-brain barrier integrity. This breach triggers significant hypothalamic neuroinflammation. Concurrently, proinflammatory cytokines (e.g., interleukin-1β, tumor necrosis factor-α) and stress-responsive circulating factors like growth differentiation factor 15 (GDF15) aberrantly reset the central metabolic set point via the melanocortin system, potentially contributing to anorexia and altered energy expenditure. Peripherally, the failure of critical nutrient-sensing axes-specifically, the ghrelin-ghrelin O-acyltransferase and insulin/insulin-like growth factor-1 signaling pathways-may impair the anabolic phosphoinositide 3-kinase/Akt/mechanistic target of rapamycin complex 1 cascade. This peripheral desensitization not only blunts the synthetic response to dietary amino acids but also precipitates a disruption of muscle proteostasis through ubiquitin-proteasome system hyperactivation and forkhead box O-mediated transcription. Concurrently, skeletal muscle undergoes significant mitochondrial bioenergetic dysfunction, further impairing nutrient utilization. By reframing PEW not simply as a state of nutrient deficiency, but as a broader dysregulation of hormonal signaling, we advocate a translational "sensitize-then-feed" therapeutic paradigm. We critically evaluate emerging targeted agents-including GDF15 antagonists, myostatin inhibitors, and ghrelin agonists. We propose that these agents could be investigated as metabolic modulators to potentially enhance the efficacy of tailored nutritional support in the uremic microenvironment.
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8. Letter to the Editor: Reconsidering the Leap from Descriptive Association to Causal Safety in the Beginnings Study.
8. 致编辑的信：重新审视Beginnings研究中从描述性关联到因果安全性的跨越PMID:日期:2026-09-04该文献暂无摘要。
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9. Toward an Optimal Diet for Health in Asia: The Asian-Mediterranean Dietary Pattern.
9. 亚洲健康最佳饮食：亚洲地中海饮食模式PMID:日期:2026-08-27With rapid population aging and lifestyle transitions, Asian countries are facing a growing burden of diet-related noncommunicable diseases (NCDs). Optimal nutrition is central to preventing NCDs and promoting healthy aging. Traditional Asian diets have many strengths, including abundant vegetables, plant-based proteins, functional foods, and nutrient-preserving cooking methods such as steaming and stewing. However, they also have limitations, including widespread use of refined carbohydrates and high sodium intake. In recent decades, the nutrition transition toward energy-dense, highly processed diets has further exacerbated these existing challenges and contributed to declining dietary quality. Despite efforts across Asia to establish healthy dietary frameworks, the region's diverse food cultures and limited research make it challenging to conceptualize a unified, culturally appropriate, and evidence-based dietary pattern. The Mediterranean diet has gained global recognition for its health benefits. However, its direct application in Asia is limited by cultural, culinary, and food system differences. In this Perspective article, the Asian-Mediterranean diet (AMED) is proposed as a culturally adapted framework that preserves the evidence-based principles of the Mediterranean diet while integrating healthy Asian foods and culinary practices. It emphasizes plant-based proteins such as soy products, healthy plant oils like canola and sesame oils, whole grains including brown rice and millet, abundant seasonal fruits and vegetables, seafood and poultry, and traditional functional foods such as fermented foods and teas. Nutrient-preserving cooking methods, together with moderate use of condiments, are encouraged. A 20-wk randomized controlled trial in Singapore is underway to evaluate the feasibility, acceptability, adherence, and health effects of AMED. As evidence accumulates, AMED has the potential to provide a scalable strategy that bridges Mediterranean evidence with Asian food cultures, promoting healthier and longer lives across Asian populations.
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10. {"_":"Expert Perspectives on Diagnosis and Management of Vitamin B Deficiency in Adults.","sub":["12"]}
10. 成人维生素B12缺乏症诊断和治疗的专家观点PMID:日期:2026-08-25There is no universally-accepted definition of vitamin B deficiency despite the severity of its medical consequences if not properly diagnosed and treated. B deficiency can arise either from inadequate dietary intake, in particular in vegans/vegetarians, or various causes of impaired uptake/availability. The latter include H. pylori and auto-immune gastritis, other causes of malabsorptions and drug side effects. Vitamin B deficiency can display diverse clinical signs and symptoms, including hematological, neurological, psychiatric and thromboembolic manifestations. The minutes and conclusions of three workshops at the FASEB "B-Vitamins and One Carbon Metabolism" Scientific Research Conferences (2022, 2024) and the 2025 International Conference on One-Carbon Metabolism, B-Vitamins and Homocysteine, the examination of the literature and the NICE/DELPHI guidelines allowed us to identify gaps and issues on diagnostic criteria and definition, evaluation of causation, and treatment strategies of vitamin B deficiency across different health care settings in adults >18 y. Our perspective is to address these gaps and issues in global guidelines to be evaluated by the IUNS (International Union of Nutrition Societies). We identified 4 main goals: 1) definition of vitamin B deficiency; 2) assessment of causality; 3) differential diagnosis and evaluation of nutritional and metabolic co-morbidities; and 4) treatment and follow-up. The objective of such guidelines should be to reduce both under- and over- diagnoses of vitamin B deficiency by integrating clinical scoring, biomarker algorithms, and to consider cause-specific treatment pathways, This should ultimately improve patient outcomes worldwide and, by arriving at uniform diagnostic criteria, facilitate the conduct, interpretation, and integration of research observations. STATEMENT OF SIGNIFICANCE: This work is the first effort to design globally applicable clinical guidelines for adult vitamin B12 deficiency that explicitly integrate clinical scoring, biomarker algorithms, and systematic assessment of causality and co-morbid nutritional states. Unlike existing regional guidelines, it proposes a combine use of the GRADE and Delphi frameworks to develop global guidelines for diagnosis and management of vitamin B12 deficiency.