Nutrients营养素
Nutrients(英文缩写 NUTRIENTS),ISSN 2072-6643,eISSN 2072-6643,中文译名:营养素 是一本学术期刊。本页汇总该期刊的最新影响因子、分区信息以及最新收录于 PubMed 的文献,帮助您快速了解期刊全貌。
发文量统计区间：2025-09-27 至 2026-09-27，按本站收录文献的发表日期统计。
期刊介绍
Nutrients 最新收录文献
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1. {"_":"Factors Associated with Dietary Behaviour During Pregnancy: An Insight from the Cohort.","i":["SaperePer"]}
PMID:日期:2026-09-07Diet during pregnancy plays a crucial role in promoting healthy dietary behaviours and positive maternal and child health outcomes. However, evidence regarding the factors associated with healthy dietary behaviours among pregnant women is limited. The study aims to assess the dietary behaviours of pregnant women and identify the sociodemographic, lifestyle, and health-related factors that influence their choices. This cross-sectional analysis included 1254 pregnant women recruited from two Northern Italian centres (Turin and Cuneo). Dietary behaviour was assessed using a questionnaire, which generated a diet-related scores. Associations between these scores and participants' characteristics were investigated using multivariable regression models. Overall, participants reported relatively favourable dietary habits and a low prevalence of risky behaviours. Higher socioeconomic position was found to be one of the strongest contributing factors to dietary behaviour (medium vs. low β (95% CI) = 1.18 (0.93, 1.42); high vs. low β (95% CI) = 1.57 (1.10, 2.04), both < 0.001). Higher dietary behaviour scores were positively associated with older maternal age, moderate physical activity, and better perceived physical and psychological health, whereas smoking and alcohol consumption were associated with lower scores. Dietary behaviour during pregnancy appears to be shaped by a complex interplay of socioeconomic, behavioural, and health-related factors rather than by nutritional knowledge alone. These findings highlight the need for tailored interventions that address the social and contextual features of dietary behaviour to encourage healthier habits during pregnancy.
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2. Vitamin (B1, B6, B12, D, and Folate) and Mineral (Iron, Selenium, and Magnesium) Status Across the Spectrum of Severe Obesity: An Integrative Multivariate Analysis of Metabolic and Nutritional Profiles.
PMID:日期:2026-09-07Obesity is frequently accompanied by metabolic dysfunction and micronutrient deficiencies, yet data on individuals with severe obesity (BMI ≥ 50 kg/m) remain limited. Understanding how vitamin and mineral status changes across the adiposity continuum may optimize personalized nutritional management in severe obesity. We analyzed anthropometric, metabolic, hepatic, and micronutrient parameters in a retrospective, single-center cohort of adults evaluated before bariatric surgery, with a BMI range of 30 to 91 kg/m (mean 48.7 ± 8.7). Measurements included bioimpedance-derived body composition, liver elastography (CAP and stiffness), and fasting laboratory parameters, vitamins B1, B6, B12, D, and folate and minerals (iron, selenium, and magnesium). Correlation analysis, principal component analysis (PCA), and random forest (RF) classification were applied to identify the variables most strongly associated with BMI and metabolic phenotypes. Several micronutrient concentrations, most notably vitamin D, folate and vitamin B6, declined progressively with increasing BMI. Vitamin D additionally correlated inversely with HbA1c. PCA revealed a separation of participants with extreme obesity driven by anthropometric and hepatic parameters, while micronutrients clustered inversely. RF classification identified HbA1c, hepatic enzymes (ALAT and γ-GT) and body-composition measures (waist circumference and visceral fat) as the strongest discriminators of T2DM, MASLD and high BMI, respectively. Combined MASLD and T2DM was associated with the most pronounced vitamin B6 depletion, whereas vitamin D was low across metabolic subgroups. Severe obesity is associated with distinct micronutrient depletion patterns that mirror metabolic deterioration. Integrating nutritional and metabolic profiling enables refined risk stratification and may, pending prospective validation, inform targeted supplementation strategies in individuals with severe obesity.
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3. Acceptability of a Korean Medicine-Based Obesity Program Among Patients Achieving Predefined Weight-Loss Targets: A Retrospective Mixed-Methods Study.
PMID:日期:2026-09-07: Although herbal medicine-based obesity treatment programs are used in obesity management, empirical research on patient acceptability remains limited. This study examined acceptability of a Korean medicine-based obesity treatment program (KM-OBP) among patients who achieved predefined weight-loss targets in routine clinical care. : Medical records and satisfaction survey data routinely collected during clinical practice at a single Korean medicine clinic were retrospectively analyzed. Patients had baseline body mass index (BMI) ≥ 30 kg/m and achieved both ≥10% weight loss and BMI ≤ 23 kg/m during follow-up. BMI trajectories and adverse-event occurrence were summarized descriptively. Satisfaction ratings were reported on a 5-point Likert scale, and free-text responses were retrospectively analyzed using the Theoretical Framework of Acceptability. : Of 3798 patients with a baseline BMI ≥ 30 kg/m and at least two BMI measurements, 37 (0.97%) met the predefined targets; 16 completed the satisfaction survey. Mean BMI change from the first to last measurement was -8.9 kg/m, and median change was -8.8 kg/m (interquartile range, -9.6 to -7.7). Common documented adverse events were constipation, nausea, and dizziness. Satisfaction ratings were descriptively high for the overall program, perceived helpfulness for obesity treatment, and herbal medicine. Among the 16 survey respondents, perceived weight-loss benefits, program structure, safety, and health improvement were described as facilitators of acceptability, whereas post-treatment weight regain, dietary burden, and financial concerns were described as barriers. : The findings characterize satisfaction and reported acceptability experiences among survey respondents within a highly selected target-achieving cohort. Interpretation is limited by outcome-based selection, potential non-response bias, the small survey sample, and the single-center design.
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4. Effects of Nutritional Supplements on Inflammatory Biomarkers in Overweight and Obese Adults: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials.
PMID:日期:2026-09-07: Obesity is frequently associated with chronic low-grade inflammation, which contributes to metabolic dysfunction. However, the comparative effects of nutritional supplements on inflammatory biomarkers in adults with overweight or obesity remain unclear. To address this gap, this paper presents a systematic review and network meta-analysis comparing 14 supplementation strategies for their effects on inflammatory biomarkers in this population. : PubMed, Embase, EBSCO, Web of Science, and the Cochrane Library were searched for randomized controlled trials published between January 2000 and January 2026. A frequentist random-effects network meta-analysis was conducted. Effects were reported as mean differences (MDs) with 95% confidence intervals (CIs), and interventions were ranked using the surface under the cumulative ranking curve (SUCRA). The confidence in network estimates was assessed using the Confidence in Network Meta-Analysis (CINeMA) framework. : A total of 60 randomized controlled trials were included. Green tea extract (MD = -2.57, 95% CI [-3.99, -1.15]) and curcumin (MD = -1.75, 95% CI [-2.74, -0.76]) both significantly reduced IL-6 levels. Synbiotics (MD = -12.25, 95% CI [-16.7, -7.8]), curcumin (MD = -2.59, 95% CI [-3.83, -1.35]) and probiotics combined with omega-3 (MD = -6.19, 95% CI [-9.12, -3.26]) had a favorable effect on TNF-α. Probiotics combined with omega-3 (MD = -1.74, 95% CI [-3.03, -0.46]), synbiotics (MD = -1.19, 95% CI [-1.85, -0.53]), zinc (MD = -1.18, 95% CI [-2.24, -0.11]), and curcumin (MD = -1.11, 95% CI [-2.14, -0.07]) all reduced CRP levels. Synbiotics (MD = 15.37, 95% CI [12.13, 18.61]) increased adiponectin levels. In contrast, no nutritional supplement significantly reduced leptin levels. Exploratory meta-regression suggested that age, exercise co-interventions, and the proportion of male participants may partly explain heterogeneity in selected outcomes. : Nutritional supplements showed biomarker-specific effects. Probiotics combined with omega-3 fatty acids, synbiotics, green tea extract, and curcumin may improve selected inflammatory biomarkers. However, differences in supplement dose, intervention duration, and participant characteristics warrant cautious interpretation and call for further high-quality trials.
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5. Camel Milk and Its Bioactive Components in Diseases Associated with Aging: A Narrative Review.
PMID:日期:2026-09-07Camel milk has long been used as a traditional health-promoting food, and growing biomedical evidence now supports its modulatory effects across multiple age-related conditions. This narrative review evaluates current experimental and clinical findings on the effects of camel milk across major categories of age-related disease, spanning metabolic dysregulation, cardiovascular pathology, neurological dysfunction, and immune-inflammatory conditions. Across these conditions, camel milk has been reported to modulate oxidative stress, chronic inflammation, and metabolic homeostasis through shared molecular pathways, including NF-κB, MAPK, PI3K/AKT, and PPAR-α/γ signaling. Mapping these effects against the twelve hallmarks of aging reveals particular engagement with chronic inflammation, deregulated nutrient sensing, and dysbiosis. Collectively, the available evidence supports a biologically plausible role for camel milk in modulating key pathological processes associated with age-related disease. However, the clinical evidence remains limited across most disease areas, and future research should prioritize standardized clinical trials and systematic mechanistic validation, with particular attention paid to the bioavailability and dose-response characterization of key bioactive components. This review provides an integrative synthesis of camel milk research within the hallmarks of the aging framework, offering a cross-disease mechanistic perspective that extends beyond single-disease or compositional approaches.
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6. Whey Protein Peptides Self-Assembled Nanoparticles with Intrinsic Cholesterol Esterase Inhibition Enhance Stigmasterol Bioaccessibility and Hypocholesterolemic Effects.
PMID:日期:2026-09-07: Stigmasterol (St) holds promise as a natural cholesterol-lowering agent, yet its poor aqueous solubility and low bioaccessibility severely constrain its application in functional foods. : In this study, we exploited whey protein peptides (WPP) with intrinsic cholesterol esterase (CEase) inhibitory activity to construct St-loaded self-assembled nanoparticles. Subsequently, we investigated its physicochemical properties and formation mechanism and evaluated its hypocholesterolemic activity through animal experiments. : Driven by non-covalent hydrophobic and hydrogen-bonding interactions, the optimized St-loaded WPP nanoparticles (St@WPP) ((234.47 ± 1.36) nm) achieved a high encapsulation efficiency (EE) of 74.73% ± 2.19%. This nano-encapsulation markedly improved St dispersibility and storage stability, and significantly elevated its bioaccessibility from 9.00% ± 0.14% to 19.41% ± 0.69% after simulated gastrointestinal digestion. St@WPP administration effectively ameliorated dyslipidemia, as evidenced by reduced serum total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C), which may be associated with reduced intestinal cholesterol availability and increased fecal cholesterol content. Moreover, St@WPP alleviated hepatic steatosis, attenuated systemic inflammation, and rebalanced gut microbiota architecture. : Collectively, the WPP shell functions as a delivery carrier that improves the water solubility and bioaccessibility of St, thereby broadening its potential for application in low-fat or aqueous-based food systems. The resulting St@WPP exhibits notable cholesterol-lowering activity, positioning it as a promising functional food ingredient with potential benefits for cholesterol management.
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7. Sparing Muscle While Losing Fat: A Narrative Review of Ketogenic Diets and Lean Mass Preservation During Weight Loss.
PMID:日期:2026-09-07Clinically meaningful weight loss reduces fat mass but is commonly accompanied by loss of fat-free mass (FFM). Ketogenic diets are of interest because ketone bodies have plausible anabolic and anti-catabolic actions. This narrative review examined whether these mechanisms translate into preservation of lean compartments or skeletal muscle during weight loss in clinical studies. MEDLINE was searched via PubMed from database inception to 14 August 2026 using terms related to ketogenic exposure, body composition, muscle metabolism, and weight loss. Evidence was synthesised according to dietary context, energy and protein intake, population, exercise exposure, measurement modality, and timing relative to carbohydrate restriction or reintroduction. Acute human studies demonstrate biological effects of ketone bodies on muscle protein turnover and signalling, but these findings do not establish long-term tissue preservation during ketogenic weight-loss diets. Supervised very-low-energy ketogenic diets generally produce weight loss composed predominantly of fat mass; however, comparative meta-analyses report small yet larger reductions in FFM or lean body mass than non-ketogenic regimens. Because most studies used hydration-sensitive compartment methods rather than direct anatomical imaging of skeletal muscle, the contributions of glycogen, water, and non-muscle lean tissues remain uncertain. Energy deficit, protein intake, resistance exercise, baseline adiposity, age, metabolic health, and training status may modify the observed response. Current evidence is insufficient to determine whether ketosis itself has either a protective or harmful effect on contractile skeletal muscle during weight loss. Ketogenic diets may be effective short-term options for selected adults with obesity, particularly within supervised protocols, but adequate protein, resistance exercise, and monitoring of strength and physical function remain the best-supported muscle-preserving strategies.
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8. Beverage Co-Consumption Profiles, Sleep, and Fatigue in Professional Army Personnel.
PMID:日期:2026-09-07Active-duty military personnel may use caffeinated and sweetened beverages to manage alertness and fatigue, but co-occurring beverage behaviours are rarely examined. We identified beverage-frequency co-consumption profiles in Spanish Army personnel and tested their cross-sectional associations with self-reported sleep and habitual physical fatigue. This cross-sectional study included 1155 active-duty Spanish Army personnel. Latent classes were estimated from ordinal frequencies of caffeinated beverages, sugar-sweetened beverages, and energy drinks; these indicators represented frequency categories rather than caffeine dose, sugar intake, or standardized serving size. Adjusted outcome models incorporated classification uncertainty and controlled for demographic, occupational, training, hydration, alcohol, smoking, and recruitment-cohort covariates. A three-class solution identified lower-frequency (47.7%), intermediate-frequency (28.3%), and higher-frequency (24.0%) profiles. Compared with the lower-frequency profile, the higher-frequency profile was associated with 0.230 h less sleep per night (95% CI -0.416 to -0.045; q = 0.022), 2.129 percentage points lower sleep efficiency (95% CI -4.177 to -0.082; q = 0.041), and 0.395 points greater habitual physical fatigue (95% CI 0.077 to 0.714; q = 0.022). Sensitivity analyses were directionally consistent. Beverage-frequency responses clustered into three profiles. The higher-frequency profile was cross-sectionally associated with shorter self-reported sleep, lower sleep efficiency, and higher habitual physical fatigue. The sleep-duration contrast was approximately 13.8 min/night, but the clinical or perceptible relevance of the sleep-efficiency and fatigue differences cannot be established from these self-reported measures. Prospective studies with product-specific dose and timing data are required to establish temporality and practical relevance.
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9. Opinions of European Dietitians About Communications Promoting Healthy Eating: An International Comparative Study.
PMID:日期:2026-09-07: Dietitians play a pivotal role in promoting healthy eating, yet their perspectives on effective communication channels and campaign priorities remain under-researched, particularly in cross-national contexts. This study compared European dietitians' opinions on communication channels and priority topics for healthy eating campaigns targeting different age groups. : A cross-sectional survey was conducted among 131 dietitians from Poland ( = 56), France ( = 36), the United Kingdom ( = 26), and Germany ( = 13). Participants rated the importance of 19 communication channels on a 5-point scale and selected three priority topics from 16 options for children, adults, and elderly populations. Data were analysed using one-way ANOVA with Bonferroni post-hoc tests and Chi-square tests (significance at < 0.05). : Interpersonal channels-dietitians' own recommendations (M = 4.10) and recommendations from family/friends (M = 4.02)-were rated the highest across all countries. Significant national differences emerged for digital channels: Polish dietitians rated social media the highest, while British dietitians were the most sceptical (apps: Poland 3.73 vs. UK 2.81, < 0.001). Limiting processed foods (60.3%) and increasing fruit/vegetable consumption (59.5%) were top child priorities, with national variations for fast food (Poland 28.6% vs. France 5.6%, = 0.006). For elderly populations, dietary diversity (49.6%) and fruit/vegetable intake (42.7%) led in terms of priorities; salt limitation was prioritised only in Poland (23.2%) and France (16.7%), = 0.017. : While European dietitians agree on interpersonal communication and core nutritional messages, national contexts shape digital tool perceptions and campaign priorities. Culturally sensitive, targeted nutrition communication strategies are needed to address diverse population needs across Europe.
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10. Positive and Negative Attitudes Toward Artificial Intelligence and E-Healthy Diet Literacy Among Adults: A Partial Least Squares Structural Equation Modeling Study.
PMID:日期:2026-09-07: This study aimed to examine the association between e-healthy diet literacy (e-HDL) and general attitudes toward artificial intelligence (AI) among adults. : This cross-sectional study included 610 adults aged 19-64 years. Data were collected through face-to-face interviews using a questionnaire consisting of five sections, including sociodemographic characteristics, digital nutrition information practices, AI use in nutrition and dietetics, the e-Healthy Diet Literacy Questionnaire (e-HDLQ), and the General Attitudes toward Artificial Intelligence Scale (GAAIS). Descriptive statistics, validity and reliability analyses, correlation analyses, and Partial Least Squares Structural Equation Modeling (PLS-SEM) were performed. Statistical significance was accepted at < 0.05. : The mean age of the participants was 33.07 ± 11.36 years, and 50.8% were female. The measurement model demonstrated acceptable reliability and convergent validity. Structural model analysis showed that positive attitudes toward AI were positively associated with e-HDL (β = 0.243, < 0.001), whereas negative attitudes toward AI were negatively associated with e-HDL (β = -0.232, < 0.001). Among the e-HDLQ dimensions, the strongest loading was observed for finding e-healthy diet information (β = 0.844), followed by applying e-healthy diet information (β = 0.641), digital healthy eating literacy (β = 0.636), judging e-healthy diet information (β = 0.308), and understanding e-healthy diet information (β = 0.277). Together, positive and negative attitudes toward AI explained 12.2% of the variance in e-HDL (R = 0.122), indicating a modest explanatory contribution. : Positive and negative attitudes toward AI were independently associated with e-HDL among adults. Although the explained variance was modest, AI attitudes may represent one of several factors associated with digital nutrition literacy, warranting further investigation in future studies.