New Microbes and New Infections新微生物与新感染
New Microbes and New Infections(英文缩写 NEW MICROB NEW INFEC),ISSN 2052-2975,eISSN 2052-2975,中文译名:新微生物与新感染 是一本学术期刊。本页汇总该期刊的最新影响因子、分区信息以及最新收录于 PubMed 的文献,帮助您快速了解期刊全貌。
发文量统计区间：2025-11-01 至 2026-10-31，按本站收录文献的发表日期统计。
期刊介绍
New Microbes and New Infections 最新收录文献
-
1. A practical nomogram for predicting multidrug-resistant organism infection in a tertiary county-level hospital to guide antimicrobial therapy.
1. 一种用于预测三级县级医院多重耐药菌感染以指导抗菌治疗的实用列线图PMID:日期:2026-09-16The prevalence of multidrug-resistant organisms (MDROs) varies geographically, and uniform standards for its management are lacking. This retrospective single-center study included 1045 unique patients after excluding duplicate isolates from 1304 non-repetitive strains collected between January and December 2023. Multivariable logistic regression was used to identify MDRO predictors and construct a nomogram. Model performance was assessed by ROC curve, calibration curve, and decision curve analysis, with bootstrap internal validation (1000 resamples). A sensitivity analysis excluding ESBL was also performed. Six independent risk factors were identified: age ≥60 years (OR = 1.47), urinary tract infection(UTIs) (OR = 1.79), ESBL production(OR = 15.18), (OR = 3.66), (OR = 29.23), and (OR = 55.48). The bootstrap-corrected AUC was 0.82 (95%CI: 0.79-0.85), with a sensitivity of 85%, specificity of 70%, PPV of 47%, and NPV of 94%. Calibration was satisfactory (slope = 1.000, intercept = 0.000, Brier = 0.136, HL P = 0.926). After ESBL exclusion, the AUC decreased to 0.70, suggesting that other variables retained independent predictive value. Age ≥60 years, urinary tract infection, ESBL production, , , and were independent risk factors for MDRO infection. The nomogram demonstrated good discrimination and calibration in this cohort and may serve as a reference for MDRO risk stratification in county-level hospitals, though external validation is warranted.
-
2. {"_":" sp. nov. and sp. nov., two novel species isolated from the breast milk of Senegalese women.","i":["Pseudomonas senegalensis","Pseudomonas millioni"]}
2. 塞内加尔假单胞菌新种和米利奥尼假单胞菌新种，两种从塞内加尔妇女母乳中分离出的新物种PMID:日期:2026-09-12Two Gram-negative, aerobic, motile and non-spore-forming bacilli, designated strains Marseille-QA0332 and Marseille-QA0892, were isolated from the breast milk of nursing mothers in Senegal. Because both strains failed to be identified by matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry, a comprehensive taxonogenomic approach was employed to determine their taxonomic positions. The complete genomes consist of single circular chromosomes of 4,577,173 bp (63.65 mol% G + C) for strain Marseille-QA0332 and 4,658,126 bp (60.22 mol% G + C) for strain Marseille-QA0892. The 16S rRNA gene analysis revealed a sequence similarity of 97.98% between strain Marseille-QA0332 and BML-PP028, while COW39 was identified as its closest relative based on digital DNA-DNA hybridization (dDDH 26.7%) and whole genome phylogeny on Average Nucleotide Identity (ANIb 81.3%). For strain Marseille-QA0892, the 16S rRNA gene sequence showed 99.00% similarity to JCM_30078 its closest relative, with an ANIb of 75.0% and a dDDH value of 21.1%. All pairwise genomic values remained well below the established thresholds for bacterial species delineation, and whole genome phylogeny confirmed the stable placement of both novel lineages within the genus . Based on these polyphasic results, we propose the description of two novel species, sp. nov. (Marseille-QA0332 = CSUR QA0332 = CECT 31294; GenBank accession number JBUCKV000000000) and sp. nov. (Marseille-QA0892 = CSUR QA0892 = CECT 31318; GenBank accession number JBUCKW000000000).
-
3. Deciphering the genotypic profiles of Carbapenem-resistant Enterobacterales: A study from a tertiary care hospital in Bihar, India.
3. 解读耐碳青霉烯肠杆菌目细菌的基因型特征：一项来自印度比哈尔邦三级医疗医院的研究PMID:日期:2026-09-10Carbapenem-resistant Enterobacterales (CRE) present a critical challenge in healthcare, especially in low-resource settings, due to limited treatment options and high mortality rates. The global prevalence of CRE is on the rise, necessitating comprehensive understanding and strategies to combat this threat. Data on carbapenemase gene distribution among CRE from eastern India remain scarce. To characterize the distribution of carbapenemase genes among CRE isolates from a tertiary care hospital in Bihar, India, and to assess their correlation with phenotypic resistance patterns. Hospital-based cross-sectional study was conducted from July 2021 to July 2023 at a tertiary healthcare centre in Bihar, India. Phenotypic methods included mCIM, eCIM, and carbapenemase inhibition assays. Genotypic analysis employed multiplex PCR to detect blaNDM, blaIMP, blaVIM, blaKPC, and blaOXA-48. PCR products were visualised by gel electrophoresis. Descriptive analyses were used to summarize genotypic and phenotypic findings. Statistical analysis was performed using SPSS v.23. Among the 98 isolates subjected to multiplex PCR-based carbapenemase gene profiling (61.22%) and (33/98, 33.67%) were predominant. blaNDM was the most frequently detected gene, found in 62/98 isolates (63.27%), predominantly in and . Phenotypic and genotypic correlations were in complete agreement for Class A and Class B carbapenemases, but discrepancies were observed in Class D carbapenemase identification. All gene-detection rates below are expressed relative to this genotyped subset of 98 isolates. High blaNDM prevalence in Bihar's CRE isolates necessitates urgent surveillance and strict infection control. Recommended therapies include Cefiderocol or Ceftazidime-avibactam plus Aztreonam. Continued molecular research and diagnostic enhancements remain critical.
-
4. An integrated One Health surveillance on cyclosporiasis outbreaks in the United States.
4. 美国环孢子虫病暴发的综合性“同一健康”监测PMID:日期:2026-09-10该文献暂无摘要。
-
5. {"_":"The 2026 outbreak in the United Kingdom: Implications for food safety, imported-food surveillance, and supply-chain traceability.","i":["Salmonella Enteritidis"]}
5. {"_":"2026年英国疫情暴发：对食品安全、进口食品监测及供应链可追溯性的影响。","i":["肠炎沙门氏菌"]}PMID:日期:2026-09-09该文献暂无摘要。
-
6. Re-emerging syphilis among women of reproductive age: temporal dynamics, demographic drivers, inequalities and projections to 2046.
PMID:日期:2026-09-09Syphilis is a re-emerging sexually transmitted infection and a major threat to reproductive and maternal health. Previous studies have described the burden among women of reproductive age (WRA), but have not quantified the demographic drivers of rising case numbers or compared changes in absolute and relative socioeconomic inequality. We examined these questions from 1990 to 2021 and projected trends to 2046. We analyzed Global Burden of Disease Study 2021 estimates of syphilis incidence and prevalence among women aged 15-49 years in 204 countries and territories. Temporal patterns were assessed using Joinpoint regression and age-period-cohort analysis. Decomposition analysis quantified demographic and epidemiological drivers. Socio-demographic Index (SDI)-related inequalities were measured using the slope index of inequality and relative concentration index, and future burden was projected using Nordpred models. In 2021, the global age-standardized incidence and prevalence rates were 279.2 and 1057.3 per 100,000 women, corresponding to 5.36 million incident and 20.5 million prevalent cases. Burden remained concentrated in lower-SDI regions and among women aged 20-29 years. Population growth accounted for 97.97% of the increase in incident cases and 99.90% of the increase in prevalent cases, while population aging partly offset both increases. Absolute socioeconomic gaps narrowed, whereas relative inequality changed little. Period rate ratios increased again during 2017-2021, and annual incident cases were projected to reach 6.95 million by 2046. Stable age-standardized rates did not translate into fewer women affected. Demographic growth and persistent relative inequality should be considered in surveillance and service planning, particularly in lower-SDI settings.
-
7. Development and clinical validation of a colorimetric isothermal assay for rapid detection of monkeypox virus.
7. 用于猴痘病毒快速检测的比色等温检测方法的开发与临床验证PMID:日期:2026-09-08Monkeypox virus has re-emerged as a global public health concern, highlighting the need for rapid, accurate, and accessible diagnostic tools. Real-time quantitative polymerase chain reaction is the reference standard for MPXV detection; however, its reliance on specialized infrastructure limits use in decentralized and resource-limited settings. This study reports the development and clinical evaluation of a colorimetric isothermal amplification assay for the rapid MPXV detection. A loop-mediated isothermal amplification assay targeting the Orthopoxvirus genus-specific B6R gene and MPXV-specific F3L gene was developed, with human β-actin as an internal control. Reactions were performed at 65 °C for 40 min and interpreted by visual color change. Clinical performance was evaluated using 130 specimens. Analytical specificity was assessed using Vaccinia virus, Buffalopox virus, Herpes simplex virus, and Varicella zoster virus. qPCR served as the reference standard. In this retrospective single-centre evaluation, the assay showed complete concordance with qPCR, correctly identifying all 50 qPCR-positive and 80 qPCR-negative specimens. Detection was achieved across the observed Ct-value range; however, a formal analytical limit of detection was not established. No cross-reactivity was observed with non-Orthopox viruses, while expected differentiation from other Orthopoxviruses was achieved. The developed colorimetric isothermal assay provides a rapid, accurate, and equipment-minimal approach for MPXV detection. The assay demonstrated performance comparable to qPCR within the evaluated clinical panel, supporting its potential utility for diagnosis and surveillance, particularly in settings with limited molecular diagnostic capacity. Further validation in larger prospective multicentre studies is required to confirm its clinical utility across diverse settings.
-
8. {"_":"Comparable severity of and malaria in hospitalized patients in the Peruvian Amazon.","i":["Plasmodium vivax","Plasmodium falciparum"]}
8. {"_":"秘鲁亚马逊地区住院患者中间日疟原虫和恶性疟原虫感染的严重程度相当。","i":["间日疟原虫","恶性疟原虫"]}PMID:日期:2026-09-08malaria has long been considered less severe than infection. However, there is growing evidence that can lead to severe and life-threatening disease, although its burden is likely to be underestimated, particularly in low-transmission settings.This study aimed to contextualize the application of World Health Organization (WHO) severe malaria criteria in a low-transmission setting by describing the clinical and parasitological profile of hospitalized malaria patients in the Peruvian Amazon. We conducted a retrospective hospital-based study at Hospital Regional de Loreto, Iquitos, Peru, from January 1, 2023, to October 30, 2025. The total hospital malaria caseload was determined from records assigned a laboratory-confirmed ICD-10 malaria diagnosis. The analytic cohort comprised hospitalized patients with microscopy-confirmed malaria who received intravenous artesunate because of severe malaria according to the WHO 2022 criteria, or inability to tolerate oral antimalarial treatment. During the study period, 519 laboratory-confirmed malaria diagnoses were recorded in the hospital; of these, 127 patients (24.5%) were hospitalized. Of these, 97 had infection (76.4%), 27 had infection (21.3%), 2 had mixed infection (1.6%), and 1 had infection (0.8%). Overall, 67 patients (52.8%) met criteria for severe malaria, which was observed in 51/97 patients with (52.6%) and 14/27 patients with (51.9%), with no significant difference between species. Notably, patients with malaria presented with severe manifestations including impaired consciousness, pulmonary oedema or acute respiratory distress syndrome, and shock. Laboratory differences between species were modest, although infections were associated with lower haemoglobin and glucose levels, while was associated with more marked thrombocytopenia. Clinical outcomes were generally favourable, with one death to which malaria-related complications may have contributed. contributed substantially to severe malaria in this low-transmission Amazonian setting and showed a severity profile similar to that of . The overlap observed between severe and non-severe presentations supports the contextual application of international severity criteria and continued recognition of the clinically important burden of malaria.
-
9. {"_":"A cross sectional seroprevalence study of and among patients with human immunodeficiency virus (HIV) in Iran.","i":["Bartonella quintana","Bartonella henselae"]}
9. {"_":"伊朗人类免疫缺陷病毒（HIV）患者中巴尔通体五日报亚种和汉赛巴尔通体的横断面血清流行病学研究。","i":["巴尔通体五日报亚种","汉赛巴尔通体"]}PMID:日期:2026-09-04and are among the most clinically relevant species infecting humans. While is a zoonotic pathogen maintained in animal reservoirs, is considered a human-restricted bacterium transmitted via the human body louse. Both species can cause a wide range of manifestations, particularly in immunocompromised individuals such as those with HIV/AIDS. This study aimed to estimate the prevalence of IgG and IgM seropositivity to these two species and to identify determinants of seropositivity. This cross-sectional study included 200 participants, comprising 97 HIV-positive patients, 53 patients with AIDS, and 50 healthy individuals as the control group. IgG antibodies against and were measured in all participants using an indirect immunofluorescence assay (IFA). In addition, IgM antibodies were assessed in a randomly selected subset of 48 participants. The overall seroprevalence of and IgG was 24.0% and 22.0%, respectively, while IgM seropositivity was 18.8% and 22.9%. No significant differences were observed in IgG prevalence among control, HIV, and AIDS groups. Individuals with a history of drug abuse had a more than threefold increased likelihood of IgG positivity. For , IgG prevalence was higher in the control and AIDS groups compared to HIV-positive individuals, though not statistically significant. The significant prevalence of IgG antibodies against both species and the presence of IgM antibodies in the selected study group, especially in HIV patients, demonstrate the clinical importance of these pathogens in at-risk populations. These findings emphasize the need for clinical vigilance in symptomatic immunocompromised patients.
-
10. {"_":"First human infection caused by in Japan.","i":["Nocardia gipuzkoensis"]}
10. {"_":"日本首次出现人类感染病例，由吉普斯夸诺卡菌引起。","i":["吉普斯夸诺卡菌"]}PMID:日期:2026-09-03An 80-year-old man with diffuse large B-cell lymphoma developed pulmonary nocardiosis caused by , with a concomitant central nervous system lesion. The isolate was identified as by gene sequencing. To our knowledge, this is the first reported human infection caused by in Japan.