CLINICS IN DERMATOLOGY皮肤病学临床
CLINICS IN DERMATOLOGY(英文缩写 CLIN DERMATOL),ISSN 0738-081X,eISSN 1879-1131,中文译名:皮肤病学临床 是一本学术期刊。本页汇总该期刊的最新影响因子、分区信息以及最新收录于 PubMed 的文献,帮助您快速了解期刊全貌。
发文量统计区间：2025-09-28 至 2026-09-28，按本站收录文献的发表日期统计。
期刊介绍
历年影响因子趋势
| JCR 数据年份 | 影响因子 | JCR 分区 |
|---|---|---|
| 2021 | 2.797 | Q3 |
| 2022 | 2.700 | Q2 |
| 2023 | 2.300 | Q2 |
| 2024 | 2.200 | Q2 |
| 2025 | 3.500 | Q1 |
CLINICS IN DERMATOLOGY 最新收录文献
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1. Biopsy-Guided Cytokine Profiling as a Tool for Precision Medicine in Psoriasis.
PMID:日期:2026-09-24Psoriasis is a clinically heterogeneous inflammatory dermatosis characterized by diverse subtypes with variable therapeutic responses. While biologic therapies targeting TNF-α, IL-17, IL-23, and IL-36 pathways have transformed disease management, treatment selection remains largely empirical and is not routinely guided by tissue-level immune profiling. In this study, we performed quantitative immunohistochemical analysis of key cytokines, IL-17A, IL-17F, IL-23p19, IL-36γ, and TNF-α, across five psoriasis subtypes (guttate, inverse, palmoplantar, plaque, and pustular) using formalin-fixed paraffin-embedded skin biopsies. Cytokine-positive dermal cell populations were quantified using digital pathology, enabling subtype-specific comparison of inflammatory signatures. Distinct cytokine patterns were observed across subtypes. Pustular psoriasis demonstrated a prominent IL-17F and IL-36γ-dominant profile, whereas plaque psoriasis exhibited broad cytokine expression with relative IL-17A predominance. Palmoplantar psoriasis showed a mixed IL-17/IL-36 signature, while guttate and inverse subtypes displayed comparatively attenuated inflammatory profiles. Because cytokine expression was quantified within the dermal compartment, these findings should be interpreted as dermal inflammatory patterns rather than as measures of total tissue cytokine expression, particularly for IL-36γ, which is also strongly associated with keratinocyte-derived epidermal responses. These findings provide tissue-level evidence of immunologic heterogeneity across psoriasis subtypes and support the concept of cytokine-driven disease endotypes. Biopsy-based cytokine profiling may represent a promising, hypothesis-generating approach for characterizing lesion-specific inflammatory patterns and potentially informing individualized therapeutic strategies, although prospective studies linking tissue profiles with treatment response are required to establish clinical utility.
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2. Skin in the Frame: Educational Value of Historic Art in Dermatology.
PMID:日期:2026-09-24Historic artworks constitute a visual corpus for dermatology education; however, the literature has not been systematically evaluated against contemporary educational standards. This review characterizes published artworks depicting dermatologic disease and assesses their curriculum alignment, clinical accessibility, and skin tone diversity. This was conducted following PRISMA guidelines across 4 databases. Studies were included if they analyzed dermatologic conditions depicted in historic art and provided clinical diagnoses. Data were extracted on artwork characteristics, presence with the American Academy of Dermatology (AAD) Basic Dermatology Curriculum, availability in a clinical decision support system (VisualDx), and estimated skin tone using the Monk Skin Tone (MST) scale. 48 studies met the inclusion criteria, encompassing 77 unique artworks. Oil paintings comprised the dominant medium. A total of 34 distinct dermatologic diagnoses were identified, with alopecia-related conditions being the most depicted. Only 40.3% of the artworks depicted conditions represented in the American Academy of Dermatology Basic Dermatology Curriculum. In contrast, all artworks had their depicted conditions available in the clinical decision support system. Skin tone assessment revealed that 6 of 10 MST were represented; however, the distribution was heavily skewed towards lighter skin tones, with Monk 01-03 accounting for 81.2% of all ratings. The historic art literature in dermatology is diagnostically broad and accessible through contemporary clinical reference tools, yet, misaligned with the formal dermatology curriculum and underrepresention of darker skin tones. Intentional curation towards curriculum-prioritized topics and skin tone diversity would be needed for this work to serve as an educational and investigative resource across the full spectrum of dermatologic practice and research.
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3. Ethical Obligations to Screen for Psychiatric Disorders and Suicidal Ideation in Patients with Alopecia Areata.
PMID:日期:2026-09-23Alopecia areata (AA) is associated with substantial psychosocial morbidity. Population-based studies have identified increased suicide-related risks, although findings are heterogeneous, which raises an ethical question regarding dermatologists' obligation to screen for psychiatric morbidity. Routine screening for depression and psychologic distress may reasonably form part of AA care. In contrast, formal suicide risk assessment should follow identification of suicidal ideation or other concerning clinical findings rather than be universally administered. This proportionate approach balances beneficence and nonmaleficence with the risks of overmedicalization, false-positive results, and limited referral resources. Screening should occur within a defined response pathway that includes assessment of positive findings, safety measures when indicated, crisis resources, and mental health referral. This approach allows dermatologists to address foreseeable psychologic harm while maintaining appropriate professional boundaries.
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4. Ethical issues when teledermatology employs tape-stripping molecular diagnostics.
PMID:日期:2026-09-23Teledermatology has narrowed geographic gaps in dermatologic care, but pigmented lesions are difficult to evaluate remotely. Mailed adhesive tape-stripping (TS) kits offer a potential noninvasive molecular adjunct, but their promised benefits (including fewer in-person visits, biopsies, and costs) remain largely unproven in practice. Herein we discuss the ethical pros and cons of TS in this setting and compare it to alternative investments such as primary care dermoscopy training and teledermoscopy. There remain unresolved concerns regarding TS cost, evidence of actual practice change, commercial oversight, data governance, and confidentiality in home specimen collection.
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5. GLP-1 Receptor Agonists in Dermatology: Prescribing Frameworks, Access, and the Emerging Pipeline.
5. GLP-1受体激动剂在皮肤科中的应用：处方框架、可及性与新兴研发管线PMID:日期:2026-09-23The rapid expansion of glucagon-like peptide-1 receptor agonist (GLP-1 RA) approvals has created a complex regulatory and practice environment for dermatologists. No GLP-1 RA currently holds a United States Food and Drug Administration (FDA)-approved dermatologic indication; all prescribing for cutaneous conditions - including psoriasis, hidradenitis suppurativa, and wound healing - remains off-label. This chapter examines the regulatory frameworks governing GLP-1 RA use in dermatology, encompassing the current FDA-approved landscape, legal and professional standards for off-label prescribing, obesity medicine certification as a competency pathway, the compounding controversy, and access, cost, and reimbursement barriers. Particular attention is given to the Anti-Kickback Statute (AKS) implications of manufacturer copay cards for Medicare beneficiaries, the Treat and Reduce Obesity Act, and evolving patient assistance strategies. Multidisciplinary collaboration, adverse event surveillance, the next-generation incretin pipeline, and ethical and equity considerations are also addressed. Practical recommendations are provided to guide dermatologists in navigating prescribing authority, reimbursement, pharmacovigilance, and the evolving evidence base.
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6. Diagnostic Orphaning: The dermatologist and the uninsured patients: What happens after the biopsy.
PMID:日期:2026-09-23Uninsured patients may receive an accurate dermatologic diagnosis and appropriate recommendation, yet remain unable to obtain treatment, because diagnostic and therapeutic services are often delivered by separate entities. We term this "diagnostic orphaning": the patient has a diagnosis, a clinician, and perhaps a referral, but no feasible route for care. This contribution proposes an adequate pathway, as an ethical standard for determining when efforts to address financial barriers constitute an adequate treatment plan.??? An adequate pathway preserves clinical integrity, is reasonably feasible, and includes accountable follow-through. Clinical integrity requires disclosure of the preferred treatment, reasonable alternatives, and consequences of delay or nontreatment; less costly care is ethical only when medically acceptable and its limitations are transparent. Practical feasibility requires attention as to whether a receiving site??? will accept the patient, whether care can occur within an appropriate interval, and whether the full episode??? of care is affordable. Accountable follow-through requires verification of subsequent handoffs and a contingenc, should a referral fail. These obligations should reflect disease urgency, likely harm from delay, and the potential benefit of further coordination; they do not require clinicians to guarantee access or personally finance the treatment plan. Practices and health systems should support referral coordination and comprehensive financial assistance, while professional organizations and government address barriers beyond individual clinicians' control. Pathway adequacy distributes responsibility according to each stakeholder's capacity to help patients to obtain care.
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7. Decision-Relevant Transparency in The Dermatology Residency Match.
PMID:日期:2026-09-23Program signaling and the financial demands of dermatology residency applications make transparency increasingly consequential. Applicants need clear guidance before committing resources, while programs need discretion to assess varied strengths and fulfill their educational missions. We propose decision-relevant transparency as an ethical standard for reconciling these interests. Information warrants disclosure when it could reasonably change whether or where an applicant applies, signals, rotates, interviews, or ranks. Programs should distinguish eligibility rules from established preferences and explain expectations concerning applicant backgrounds, research years, visiting rotations, and signaling. These expectations should be public, understandable, and current before applicants act on them. The obligation is strongest when a policy would exclude an applicant from consideration and should extend to commitments that involve substantial applicant time or money. Programs need not disclose confidential deliberations, rank lists, or exact scoring weights, nor provide individualized feedback to every unsuccessful applicant. Responsibility for implementation rests with programs that control selection information, national organizations that can coordinate reporting, mentors who help students interpret disclosures, and applicants who use them. Structured advising is particularly important for students without a home dermatology program. This approach seeks to reduce reliance on private access to information while preserving holistic review, applicant privacy, and a reasonable workload for selection committees.
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8. Forensic Dermatology of Tattoos: Part 2. Types of Tattoos that can Present in a Forensic Setting.
PMID:日期:2026-09-23A tattoo is created by inoculating pigment into the skin. It is a form of body modification. Tattoos are an essential feature in forensic dermatology. The forensic dermatology of tattoos is presented in four contributions. Part 1) discusses the epidemiology of tattoos in a forensic setting (Clin Dermatol 2027; xxx.xxx). Part 2) examines the types of tattoos that can present in a forensic setting. The third contribution in the series (Part 3) considers the cutaneous diseases, infections, lesions, and malignancies with tattoos in a forensic setting. The fourth paper in the series (Part 4) discusses the forensic aspects of tattoos. Forensic-associated tattoos can present as medical tattoos, breast cancer-associated tattoos, mucosal tattoos, and cosmetic tattoos. Medical tattoos can provide crucial insight into a person's health history. Radiotherapy tattoos, nipple-areola-complex tattoos, and post-mastectomy tattoos are breast cancer-associated camouflage. The cornea, gastrointestinal tract, lips, and oral mucosa are potential locations of mucosal tattoos. The forensic evaluation may reveal one or more cosmetic tattoos; the presence of a cosmetic tattoo may assist in identifying an unknown decedent. Comprehension of the forensic significance of tattoos is important for forensic investigators who evaluate those with tattoos.
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9. Workplace Accommodations for Alopecia Areata: A Framework for Dermatologists.
PMID:日期:2026-09-22Alopecia areata (AA) may impair occupational functioning through psychosocial distress, disease visibility, concerns regarding hair-prosthesis displacement, and unwanted disclosure. Importantly, occupational impairment may not parallel the extent of visible hair loss. Workplace accommodations can reduce barriers to employment, but dermatologists may face uncertainty regarding when accommodation is appropriate, what information to provide employers, and how to balance immediate support with long-term adaptation. We propose a practical five-step framework for evaluating workplace accommodation requests in AA.
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10. Synthetic Patients as a New Validation Standard for Artificial Intelligence in Dermatology.
PMID:日期:2026-09-22该文献暂无摘要。