Journal of Infection and Public Health感染与公共卫生杂志
Journal of Infection and Public Health(英文缩写 J INFECT PUBLIC HEAL),ISSN 1876-0341,eISSN 1876-035X,中文译名:感染与公共卫生杂志 是一本学术期刊。本页汇总该期刊的最新影响因子、分区信息以及最新收录于 PubMed 的文献,帮助您快速了解期刊全貌。
发文量统计区间：2025-09-27 至 2026-09-27，按本站收录文献的发表日期统计。
期刊介绍
历年影响因子趋势
| JCR 数据年份 | 影响因子 | JCR 分区 |
|---|---|---|
| 2021 | 7.537 | Q1 |
| 2022 | 6.700 | Q1 |
| 2023 | 4.700 | Q1 |
| 2024 | 4.000 | Q1 |
| 2025 | 4.800 | Q1 |
Journal of Infection and Public Health 最新收录文献
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1. Epidemiological characteristics of cutaneous leishmaniasis in Fars Province, Southern Iran: A registry-based study, 2020-2024.
PMID:日期:2026-09-18Cutaneous leishmaniasis (CL) is a neglected tropical parasitic disease endemic in many parts of Iran, and Fars Province is recognized as one of the most important foci. Timely and accurate epidemiological data are essential for effective disease control and prevention. Accordingly, this study was designed to investigate the demographic and clinical epidemiological status of CL in Fars Province between 2020 and 2024. This retrospective registry-based surveillance study analyzed 12,183 laboratory-confirmed cases of cutaneous leishmaniasis (CL) recorded in the Fars Provincial Health Surveillance System between March 2020 and March 2024. Demographic, clinical, and parasitological variables including age, sex, occupation, nationality, place of residence, lesion count, anatomical location, and Leishmania species were extracted from the registry. The mean age was 30.02 ± 20.96 years (range: <1-99 years). Males accounted for 53.25% of cases (P < 0.001), and individuals aged ≤ 20 years represented the largest proportion of cases (P < 0.001). Urban residents comprised 67.3% of cases (P < 0.001). Two counties, Shiraz (37.81%) and Marvdasht (17.45%), accounted for more than half of all reported cases. Among the 4454 cases with available species data in the registry, Leishmania major was the predominant species (84.5%), while Leishmania tropica accounted for 15.5%. The proportion of cases recorded as L. tropica in the registry increased from 3.98% in 2022-27.20% in 2024. Housewives constituted the largest occupational group (26.9%). Most patients presented with a single lesion (44.32%), and the upper extremities were the most frequently affected anatomical site (38.33%). A significant association was observed between lesion count and sex (P = 0.003). Our findings reveal a disproportionate burden of reported CL cases among males and younger individuals, a substantial urban concentration of cases, and an increasing proportion of registry-recorded L. tropica cases among those with available species data. Shiraz and Marvdasht were identified as key transmission hotspots warranting immediate, targeted public health interventions. Collectively, these data offer a robust evidence base to guide resource allocation and stratified control efforts in high-risk areas.
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2. Early bacterial infectious complications following kidney transplantation: Epidemiology, microbiology and clinical outcomes.
PMID:日期:2026-09-18Early bacterial complications remain a major source of morbidity after kidney transplantation. We evaluated the epidemiology, microbiology, risk factors, and clinical implications of bacterial complications occurring within 60 days after kidney transplantation. We performed a retrospective cohort study of 365 consecutive adult kidney transplant recipients at a high-volume transplant center. Bacterial complications, microbiologic findings, risk factors, and clinical outcomes were analyzed. Multivariable logistic regression was used to identify factors independently associated with infection. Within 60 days after transplantation, 166 recipients (45.5%) developed at least one bacterial infection. Urinary tract infection (UTI) was the predominant complication, occurring in 142 recipients (38.9%), followed by surgical site infection (SSI) in 34 (9.3%) and bacteremia in 30 (8.2%). The median time to first infection was postoperative day 13 (IQR 8-21). Multi-site infection occurred in 45 recipients (27.1% of infected recipients; 12.3% of the overall cohort), with UTI present in 84.4% of cases. Among recipients with bacteremia, 80.0% had a concurrent UTI, and urine and blood cultures demonstrated organism concordance in 87.5% of cases. Gram-negative organisms predominated across infection sites, with Escherichia coli, Klebsiella species, and Pseudomonas aeruginosa among the most frequently isolated pathogens. Enterococcus faecalis was also frequently identified, particularly in urinary and surgical site cultures. On multivariable analysis, female sex (aOR 1.90, 95% CI 1.19-3.03; p = 0.007), longer pretransplant dialysis duration (aOR 1.09 per year, 95% CI 1.01-1.17; p = 0.027), and DGF (aOR 1.82, 95% CI 1.11-2.99; p = 0.018) were independently associated with bacterial complications. Bacterial complications are common during the early post-transplant period and are dominated by UTI. The frequent coexistence of UTI with bacteremia and SSI, together with high microbiologic concordance between urine and blood cultures, suggests that these complications are often interconnected rather than independent events. Strategies aimed at preventing UTI may help reduce the burden of more complex post-transplant bacterial complications.
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3. Factors affecting hand hygiene adherence among critical care healthcare workers: A systematic review.
PMID:日期:2026-09-17Hand hygiene (HH) is the most effective and cost-efficient strategy to prevent healthcare-associated infections, yet compliance remains suboptimal, particularly in intensive care units (ICUs) and emergency departments (EDs). This study aimed to analyse the main factors influencing HH compliance among healthcare workers in critical care settings. A systematic review of studies investigating barriers to HH adherence in ICUs and EDs was conducted according to PRISMA guidelines. Thirty studies published between 1994 and 2024 were included, mostly quantitative, with sample sizes ranging from 25 to 600 healthcare workers. The review identified major structural and organizational barriers, such as limited availability of materials, time constraints, suboptimal sink placement, high workload, and overcrowding. Personal factors, including skin irritation and glove use, as well as coworkers' attitudes, were also associated with reduced compliance. Persistent contextual barriers hinder HH adherence, underscoring the need for continuous education alongside organizational, logistical, and architectural support.
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4. Molecular epidemiology, genetic characteristics, and antimicrobial resistance of Staphylococcus capitis clinical isolates: First identification of the NRCS-A and proto-NRCS-A clones in Japan.
PMID:日期:2026-09-14A pathogenic clone of Staphylococcus capitis, NRCS-A, possesses specific virulence factors and shows broader antimicrobial resistance (AMR). The present study aimed to analyze the genetic characteristics and AMR profiles of S. capitis clinical isolates and determine the prevalence of the NRCS-A clone in Japan. S. capitis isolates from clinical specimens were analyzed for the presence of virulence factors and AMR-associated genes by PCR and sequencing. Genetic classification of S. capitis isolates was performed by an in-house multilocus sequence typing (MLST) based on four loci (arcC-rpoB-gap-tuf). A total of 194 S. capitis isolates (44 subsp. capitis and 150 subsp. urealyticus) were collected for 7 months. mecA was detected in 33% (63/194) of isolates (only subsp. urealyticus), while the most common AMR determinants identified were fosSC (77%, n = 150) and blaZ (59%, n = 114). Virulence factors associated with the NRCS-A clone, nsr and tarJ, were found in 20% (n = 39) and 37% (n = 71) of isolates, respectively. Both nsr and tarJ were present in 13 isolates (7%), among which three isolates had the traits of the NRCS-A clone (SCCmec-V with CRISPR/Cas-IIIA; SCCcad/ars/cop in two isolates), whereas the remaining 10 isolates were considered presumptive proto-NRCS-A clone (nsr+, tarJ+, CRISPR-Cas-IIIA/SCCmec-negative). By the MLST scheme, all the S. capitis isolates were differentiated into 48 STs and six major clonal complexes (CCs). Isolates assigned to the NRCS-A clone were classified as ST13 or ST14 in CC1, which was a minor lineage of S. capitis subsp. urealyticus. Similarly, most isolates of proto-NRCS-A clone were grouped into CC1, with ST13 being dominant. The present study first revealed the presence of NRCS-A and proto-NRCS-A clones among S. capitis clinical isolates in Japan. Careful monitoring and attention to these clones may be necessary in clinical settings.
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5. Rising global threat of hypervirulent Klebsiella pneumoniae: Insights into virulence factors, pathogenicity, and molecular mechanisms.
PMID:日期:2026-09-11Hypervirulent Klebsiella pneumoniae, a novel variant with unique phenotypic and genotypic features that enhance pathogenicity and epidemic potentiality, has become a serious worldwide public health emergency. Even healthy people can contract invasive infections from hypervirulent K. pneumoniae (hvKp), which shows higher virulence than classical K. pneumoniae (cKp). Because of its colonization in the human gut, it can spread and cause serious morbidity in community-acquired diseases like meningitis, endophthalmitis, and liver abscesses. To increase its pathogenic potential, hvKp possesses a distinct collection of virulence factors that go beyond antibiotic resistance. Capsule, fimbriae, siderophores and LPS are the major essential elements responsible for pathogenicity. Siderophores are a major class of secondary metabolites that play a key role in facilitating the transport of iron across bacterial cell membranes into the cytoplasm. This review examines numerous virulence factors that contribute to the infectious capacity of hvKp, including the polysaccharide capsule, biofilm formation, siderophore production (aerobactin, enterobactin, salmochelin, and yersiniabactin), and adhesins involved in host cell colonization and pathogenicity. Additionally, this review may evaluate the specific role of virulence regulatory genes in balancing antibiotic resistance and pathogenicity. Understanding these virulence genes and their mechanisms is essential for the development of effective diagnostic, preventive, and therapeutic approaches to address the escalating threat of hvKp pathogenesis. This is a novel and impactful review that should go beyond the description of virulence factors and pathogenicity and should highlight how understanding these mechanisms can inform the development of novel therapeutic strategies against hypervirulent Klebsiella pneumoniae (hvKp).
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6. Genomic landscape of Escherichia coli from swine to identify antibiotic resistance, pathogenicity, and dissemination potential: Implications for environmental and public health.
PMID:日期:2026-09-11The emergence of antimicrobial-resistant Escherichia coli in livestock, particularly swine, represents a growing concern for animal, environmental, and public health. Unorganized swine production systems may act as reservoirs for multidrug-resistant strains with zoonotic potential. This study analyzed E. coli isolates recovered from swine in Karnataka, India using antimicrobial susceptibility testing and PCR screening for ESBL/AmpC genes (bla, bla, bla, bla). Ten positive isolates were subjected to whole-genome sequencing (WGS) using the Illumina MiSeq platform and bioinformatic analyses included the identification of antimicrobial resistance genes (ARGs), virulence factors (VFs), mobile genetic elements (MGEs), plasmid replicons, and biofilm-associated genes. Molecular typing (MLST, serotyping, CH typing, Clermont phylogrouping) and comparative phylogenomic analysis were performed with 53 global swine-origin E. coli genomes. Multiplex PCR confirmed 25/29 isolates as E. coli and PCR identified ESBL and/or AmpC genes in 10 E. coli isolates (three - single ESBL genes, four- multiple ESBL genes, one -ESBL+ AmpC co-occurrence and two carrying only AmpC). WGS revealed 48 unique ARGs, with bla and sul1 being most prevalent, ESBL (bla) and AmpC (bla) genes were identified in two and three isolates, respectively. The integron-integrase genes (intI1/intI2) associated with dfrA17 in two isolates suggests involvement of MGEs in resistance gene carriage and virulome analysis identified 34 conserved virulence genes. High genetic diversity with nine sequence types, multiple phylogroups (A, B1, C, F, G), seven serotype combinations, and CH typing revealed alleles such as fimH58 and fumC4. High Simpson's diversity indices (0.978 for MLST; 0.952 for serotypes) confirmed this heterogeneity. Comparative phylogenomics indicated clustering of Indian isolates (e.g., ST624, ST117) with global lineages. The co-occurrence of diverse resistance determinants, VFs, and MGEs in swine E. coli highlights their genomic diversity. These findings underscore the need for integrated genomic surveillance and antimicrobial stewardship within a One Health framework.
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7. Bloodstream infection in patients with pyogenic liver abscess: Predictors, microbiological characteristics, and in-hospital outcomes.
PMID:日期:2026-09-11To investigate the predictors, microbiological characteristics, and in-hospital outcomes of bloodstream infection (BSI) in patients with pyogenic liver abscess (PLA). We conducted a retrospective single-center cohort study of patients with PLA who underwent blood culture testing during hospitalization between January 2011 and December 2023. Clinical, laboratory, imaging, microbiological, treatment, and in-hospital outcome data were compared between patients with and without BSI. Multivariable logistic regression was used to identify independent predictors of BSI, and adjusted models were applied to examine the associations between BSI and in-hospital outcomes. A total of 347 patients with PLA were included, of whom 47 (13.5%) had BSI. Compared with non-BSI patients, those with BSI more frequently had systemic inflammatory response syndrome on admission (48.9% vs. 24.4%), higher procalcitonin levels (23.46 vs. 5.69 ng/mL), lower ALB levels (27.53 vs. 31.20 g/L), and gas-forming abscesses (27.7% vs. 10.3%). In multivariable analysis, jaundice (OR 8.17, 95% CI: 1.90-35.06) and higher procalcitonin (OR 1.02, 95% CI: 1.00-1.05) were independently associated with BSI. Klebsiella pneumoniae was the predominant pathogen in both blood and pus cultures. BSI was associated with greater treatment burden and worse in-hospital resource utilization, including more frequent use of ≥ 3 antibiotics (40.4% vs. 18.3%), longer hospital stay (19.34 vs. 14.74 days), and higher hospitalization costs (5399.21 vs. 3888.42 USD). Further stratification by combined blood and pus culture results showed that the Blood+/Pus+ subgroup had the highest inflammatory burden, treatment intensity, and hospitalization burden. BSI in PLA was associated with a greater inflammatory burden, increased treatment intensity, and worse in-hospital resource utilization. Combined interpretation of blood and pus culture results may help identify patients with greater clinical burden and support early risk stratification, closer inpatient monitoring, and timely reassessment of antimicrobial therapy in PLA.
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8. COVID-19's illness script: From its origins to the present day. A Tinguely-like kinetic sculpture.
PMID:日期:2026-09-10Illness scripts (IS) are mental representations of diseases formed through formal and experiential learning. Rich and mature IS are promptly activated in contextual information, expediting diagnosis and management. The COVID-19 IS developed atypically-experts had to build it without prior knowledge. This study examines its evolution from early pandemic stages to the present, assessing its richness, maturity, uncertainties, influencing factors, and its impact on clinical supervision. A qualitative study was conducted at Geneva University Hospitals from December 2022 to May 2023. Volunteer physicians from various divisions participated in semi-structured interviews, which were recorded, transcribed, coded, and analyzed using deductive and inductive thematic approaches. The theoretical frameworks concerning IS development, richness, and maturity, as well as situated cognition theory, were used in the analysis. Twenty physicians participated. The COVID-19 IS, developed from diverse sources, is now rich and mature. COVID-19 is primarily viewed as a respiratory infection, especially in vulnerable patients, with corticosteroids and supplemental oxygen as primary treatments. However, instability remains: atypical presentations still occur, viral variants raise treatment concerns, and long COVID introduces additional complexity. Political, institutional, and individual factors shape the IS. While the IS itself was shared across seniority levels, participants reported an erosion of the supervisor's epistemic authority: attending physicians saw a threat to trainees' formation, chief residents a shift toward collaborative reasoning, and residents a move from knowledge transmission to relational support. The pandemic harmed medical training, as COVID-19 overexposure led to poor IS development for common illnesses. Despite atypical construction, the COVID-19 IS has become rich and mature, though some uncertainties persist. Moreover, it is operational and effective. It was shaped through dynamic interactions across multiple levels-from the immediacy of patient encounters to the broader institutional and sociopolitical contexts in which clinical practice unfolds.
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9. Associations of age, COVID-19 vaccination, and SARS-CoV-2 infection history with health-related quality of life in a community-based longitudinal cohort in Singapore.
PMID:日期:2026-09-09To assess associations between COVID-19 infection, Long COVID, and health-related quality of life (HR-QoL) in a prospective community serological cohort in Singapore. Participants with mild or no infection were followed over 30 months (from August 2020). HR-QoL was measured using the SF-36 at visits 5 and 6 (December 2022-September 2023). Mixed-effects linear regression models examined associations between infection status and SF-36 domains, adjusting for sociodemographic and clinical factors, with age-time since infection interactions. Among 1106 participants (aged 16-94 years), COVID-19 infection was associated with lower HR-QoL, with associations differing by age and time since infection. Participants aged ≥ 65 years had lower physical and mental HR-QoL, including beyond one-year post-infection. Among participants aged 16-64 years, lower HR-QoL was observed during the first 45 days after infection. Long COVID symptoms were associated with lower HR-QoL across multiple domains. Receipt of ≥ 3 mRNA vaccine doses was associated with higher physical and mental HR-QoL scores. Post-COVID HR-QoL differed substantially by age. Older adults had lower HR-QoL across multiple domains, whereas younger participants showed lower HR-QoL primarily during the early post-infection period. Vaccination and the absence of Long COVID were associated with better HR-QoL outcomes.
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10. A changing climate of infections: Humidity is associated with Escherichia coli bloodstream infections in Tokyo, 2014-2024.
PMID:日期:2026-09-08Seasonal variations in bloodstream infections (BSIs) have been reported for several bacterial species. The independent effects of weather variables, such as humidity, temperature, precipitation, and bright sunshine duration have not been fully considered. We analyzed monthly BSI incidence rates at Teikyo University Hospital, Tokyo, from January 2014 through December 2024. Incidence was defined as the number of new BSI cases per 10,000 inpatient-days each month. Meteorological data were obtained from the Japan Meteorological Agency. Absolute humidity (AH) was residualized against temperature and calendar-month fixed effects (AH) to isolate the humidity component independent of temperature and seasonality. Monthly BSI counts were analyzed using negative binomial regression models with a log link and an offset for monthly inpatient-days to assess associations with weather variables. During the 11-year period, AH demonstrated a significant association with Escherichia coli (E. coli)-specific BSI incidence (IRR 1.11 [95% CI 1.01-1.21], p = 0.029). In contrast, other weather variables, such as temperature, precipitation and bright sunshine duration showed no association with all-cause and E. coli-specific BSIs. We found that rising humidity was associated with increased E. coli-specific BSI incidence. Because increments in temperature and humidity are both expected with global warming, continued surveillance of climate-related trends in bloodstream infections is warranted.