Clinical Oral Investigations临床口腔研究
Clinical Oral Investigations(英文缩写 CLIN ORAL INVEST),ISSN 1432-6981,eISSN 1436-3771,中文译名:临床口腔研究 是一本学术期刊。本页汇总该期刊的最新影响因子、分区信息以及最新收录于 PubMed 的文献,帮助您快速了解期刊全貌。
发文量统计区间：2025-09-27 至 2026-09-27，按本站收录文献的发表日期统计。
期刊介绍
历年影响因子趋势
| JCR 数据年份 | 影响因子 | JCR 分区 |
|---|---|---|
| 2021 | 3.607 | Q2 |
| 2022 | 3.400 | Q2 |
| 2023 | 3.100 | Q1 |
| 2024 | 3.100 | Q1 |
| 2025 | 3.600 | Q1 |
Clinical Oral Investigations 最新收录文献
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1. Does individual pain threshold influence postoperative pain after connective tissue graft surgery?
PMID:日期:2026-09-25Postoperative pain and discomfort remain common concerns in periodontal plastic surgery involving gingival grafts; however, the influence of individual pain sensitivity on postoperative outcomes remains poorly understood. This study evaluated whether preoperative pain sensitivity is associated with postoperative pain intensity and analgesic consumption after coronally advanced flap (CAF) combined with subepithelial connective tissue graft (SCTG). In this exploratory clinical study, 25 participants undergoing CAF + SCTG were assessed preoperatively for psychological factors (pain catastrophizing and fear of pain) and cold pain sensitivity using a cold pressor test. Cold pain threshold (CPT) and cold pain tolerance (CPTol) were determined by recording the time to pain onset and maximum tolerated immersion in cold water, with corresponding visual analog scale (VAS, 0-100) scores. Postoperative pain, discomfort, and analgesic intake at donor and recipient sites were recorded daily for 14 days using VAS-based diaries. Hierarchical and K-means clustering identified postoperative pain profiles, and binomial logistic regression evaluated predictors of cluster membership. Two postoperative pain profiles were identified. Cluster 1 showed lower pain intensity and lower analgesic consumption, whereas Cluster 2 exhibited higher postoperative pain and greater analgesic use. Higher initial pain intensity during the cold pressor test significantly increased the odds of belonging to Cluster 2, with each unit increase associated with an approximately 11.2% increase in the odds of membership. In contrast, cold pain threshold, pain tolerance, and psychological variables were not associated with postoperative pain profiles. Preoperative pain intensity during a cold pressor test may help identify patients at greater risk of postoperative pain after CAF + SCTG, suggesting a simple approach for preoperative risk stratification. Assessment of individual pain sensitivity before surgery may help clinicians anticipate postoperative discomfort and tailor analgesic strategies to improve patient-centered outcomes following root coverage procedures.
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2. Biomechanical and weibull-based evaluation of bioceramic root filling and coronal restoration designs in apically resorbed premolars.
PMID:日期:2026-09-25This study aimed to evaluate the effects of different root canal filling strategies and coronal restoration types on the biomechanical behavior of mandibular premolars with simulated apical external root resorption using three-dimensional finite element analysis (FEA) combined with a two-parameter Weibull-based fracture probability assessment. MTA plug + gutta-percha + composite core and ceramic crown (MTA/GP/CC), MTA full-canal obturation + composite core and ceramic crown (MTA/CC), MTA plug + gutta-percha + hybrid-ceramic endocrown (MTA/GP/ECR), MTA full-canal obturation + hybrid-ceramic endocrown (MTA/ECR), Biodentine plug + gutta-percha + composite core and ceramic crown (B/GP/CC), Biodentine full-canal obturation + composite core and ceramic crown (B/CC), Biodentine plug + gutta-percha + hybrid-ceramic endocrown (B/GP/ECR), Biodentine full-canal obturation + hybrid-ceramic endocrown (B/ECR), and an intact tooth (IT). A 300 N oblique load was simulated for all models. FEA showed that the highest tensile stress in coronal restorations occurred in the MTA/GP/ECR model, whereas the lowest values were found in the MTA/ECR and B/ECR models. Within root dentin, maximum tensile stress was highest in the B/GP/CC model (0.683 MPa) and lowest in the MTA/ECR configuration (0.534 MPa). At 300 N, Weibull-based system fracture probabilities ranged from 0.0180% to 0.0192% for full-coverage crown (CC) designs and from 0.0157% to 0.0167% for ECR designs. For matched root-filling strategies, ECR configurations showed approximately 13-14% lower relative system fracture probabilities than the corresponding CC configurations. Complete bioceramic obturation combined with a hybrid-ceramic endocrown (ECR) showed a favorable biomechanical profile and the lowest relative Weibull-based system fracture probabilities among the evaluated configurations. Within this idealized FEA-Weibull framework, ECR restorations combined with full-canal bioceramic obturation showed modestly lower relative system fracture probabilities than matched full-coverage crown configurations. The probabilistic response was dominated by root dentin rather than by direct fracture contributions from the restorative materials.
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3. Postoperative velopharyngeal function changes in cleft palate children: A long-term retrospective study.
PMID:日期:2026-09-25This study aimed to delineate the longitudinal trajectory of velopharyngeal function (VPF) following primary cleft palate repair and characterize potential associated parameters to inform early treatment planning. This retrospective study analyzed 313 consecutive patients who underwent primary cleft palate repair before age 5, with minimum 3‑year follow‑up and three postoperative timepoints. Patients with a history of professional speech therapy were excluded to observe the natural history of VPF. Data from medical records, perceptual speech evaluations, and imaging assessments were analyzed. A generalized additive model assessed the association between first follow‑up interval and VPF consistency. Multivariable logistic regression identified independent factors associated with VPF improvement and deterioration. Stable VPF across all follow‑ups was observed in 75.72% (237/313) of patients, while approximately one-quarter of patients (24.28%) demonstrated changes in VPF during longitudinal follow-up after primary palatoplasty. Longer first follow‑up interval was associated with higher consistency, with predicted probabilities of 80% at 2.16 years and 95% at 3.66 years post‑surgery. Patients with VPF changes underwent repair significantly later than stable patients (P = 0.001). Velar elevation angle was independently associated with VPF improvement (P < 0.001). Older age at repair (P = 0.033) and lower velopharyngeal ratio (P = 0.008) were independently associated with VPF deterioration. Patients with cleft palate exhibited long‑term instability in VPF following primary palatoplasty. Velar elevation angle was associated with VPF improvement, while older age at repair and lower velopharyngeal ratio were associated with deterioration. These findings provide preliminary evidence to support a risk-stratified follow-up strategy. However, the proposed framework is hypothesis-generating and requires external validation in prospective cohorts before clinical implementation.
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4. Incidental findings from panoramic radiographs: A systematic review with meta-analysis.
PMID:日期:2026-09-24The use of radiographs is widely spread, both among general dentists and specialists, since it provides a view of the oral and perioral tissues using a relatively easy-to-acquire and low-dose image. The aim of this systematic review was to critically appraise and summarize evidence from clinical studies on the prevalence of incidental findings from panoramic radiographs. Systematic literature searches without restrictions were undertaken in eight databases from inception up to January 2026 for studies reporting on incidental findings from panoramic radiographs of any dental patients. After duplicate study selection, data extraction, and risk-of-bias assessment using a custom tool based on the Joanna Briggs Institute's tool for prevalence studies, random-effects meta-analyses were performed, followed by subgroup, meta-regression, and sensitivity analyses. Twenty-five studies covering a total of 66 882 patients (44.1% male; average age 28.9 years) were included. The prevalence of incidental findings ranged from 5.2% to 88.1%, with average distribution prevalences between 22.9% and 53.1%, but heterogeneity was high across studies. Incidental findings were most often related to airways (30.9%), followed by teeth (12.2%), soft-tissue calcifications (9.4%), spine (7.4%), radiopacities (7.1%), and temporomandibular joint (1.8%). However, several methodological issues were present in the included studies (incomplete reporting of patient- or radiography-related details, incomplete categorization and reporting of the severity of findings, small sample sizes, and issues with research transparency). Evidence indicates that incidental findings are common in panoramic radiographs of dental patients. Although many incidental findings are clinically insignificant, some may have important implications. When a dental panoramic image is justified, it should be adequately assessed for incidental findings by either a specialist oral and maxillofacial radiologist or a dentist with appropriate training and experience.
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5. Subsequent depression in patients with lip and head and neck cancer: a population-based primary care analysis.
PMID:日期:2026-09-24Lip and head and neck cancer is associated with a significant psychological burden. However, there is a lack of evidence from German primary care regarding the association between lip and head and neck cancer and subsequent depression. Our study aimed to determine the association between lip and head and neck cancer diagnosis and subsequent depression diagnosis. Using the German Disease Analyzer database (IQVIA), we conducted a retrospective cohort study of adults (≥ 18 years) with incident lip and head and neck cancer (ICD-10 C00-C06) initially documented in general practices between 2005 and 2023. Individuals with prior mental health conditions were excluded. Lip and head and neck cancer patients were propensity-score matched (1:10) to cancer-free individuals. Incident depression diagnosis within five years after the index date was the primary outcome, analyzed using Kaplan-Meier curves and conditional Cox regression. The study included 1,852 patients with lip and head and neck cancer and 18,520 matched non-cancer individuals. Lip and head and neck cancer was associated with a higher incidence of subsequently diagnosed depression (hazard ratio (HR) = 1.62; 95% confidence interval (CI) 1.40-1.87). Tongue cancer was found to be the tumor site most consistently associated with subsequent depression across all subgroups (HR = 2.05; 95% CI 1.65-2.53); base-of-tongue cancer (C01) and tongue cancer (C02) showed independently consistent associations when analyzed separately (HR = 2.10 and HR = 2.01, respectively). Stronger associations were observed among adults aged 60 years or younger and men. Patients with distant metastasis showed a particularly strong association with subsequent depression (HR = 2.59; 95% CI 1.85-3.63). Patients with lip and head and neck cancer, particularly those with tongue cancer, younger individuals, and patients with metastases, showed a significantly higher incidence of subsequent depression. These results highlight the importance of systematic mental health screening and targeted psychosocial support in routine oncological and primary care settings to enhance patient outcomes.
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6. A randomised controlled trial comparing thermoformed and 3D-printed retainers in young adults: evaluation of surface roughness, surface morphology, and mechanical properties.
PMID:日期:2026-09-24This study aimed to evaluate and compare the surface roughness, surface morphology, and mechanical properties of direct 3D-printed retainers (3DPR) and thermoformed retainers (TFR) after six months of intraoral use. This study reports a secondary laboratory objective of a previously published randomised controlled trial (Boo et al. 2026) and included a subset of 10 participants (n = 5 per group). TFRs were fabricated using 1.0 mm Erkodur blanks, while 3DPRs were designed with a uniform thickness of 0.75 mm and printed using NextDent Ortho Flex resin. For each participant, unused upper and lower retainers served as controls, while the corresponding retainers were retrieved after six months of intraoral use. Surface roughness parameters (Ra and Rq) were measured on the cameo and intaglio surfaces using contact profilometry. Surface morphology was evaluated using scanning electron microscopy. Mechanical properties were assessed by instrumented indentation testing. Upper- and lower-arch measurements were averaged at the participant level for statistical analysis. The 3DPR group generally exhibited higher surface roughness values than TFR, with statistically significant differences observed at the intaglio surface at both time points and at the cameo surface after six months (Ra and Rq, p < 0.05). No significant within-group changes in Ra or Rq were observed over time. Surface morphology analysis demonstrated more pronounced surface irregularities in 3DPR compared with TFR, which showed relatively smooth surfaces. For mechanical properties, TFR demonstrated statistically significantly higher Martens hardness, indentation modulus, and indentation hardness than 3DPR at baseline (all p < 0.05), with further increases after six months, whereas 3DPR showed declines in these properties (p < 0.05). In this pilot laboratory study, 3DPR showed higher surface roughness and more significant decreases in indentation-based mechanical properties after six months of intraoral use compared to TFR, indicating potentially lower mechanical durability under these conditions. However, these findings should be interpreted cautiously given the small sample size.
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7. The DC/TMD Conundrum.
PMID:日期:2026-09-24The goal of any disease classification system, based on the core principles of translational and evidence-based medicine, is to develop management plans that provide appropriate high-quality patient care based on accurate diagnoses, according to the core principles of translational medicine. Within these premises, the current classification schemes that are available in the field of temporomandibular disorders (TMDs) practice are hardly clinically useful and patient oriented. The publication of the Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) is a milestone achievement that serves as a foundation of the discipline, but it clearly lacks the needed impact on the everyday practice and treatment planning. From being the potential solution to the necessity of standardizing TMD classification, the DC/TMD became an enigma in search of a solution: how to progress and move on to embed current evidence-based knowledge into a diagnostic and classification schemes that can be adopted both for academic and clinical purposes? This manuscript provides an overview of the reasons why the time has come to rethink, reconceptualize and reconfigure the currently accepted concepts and develop concepts based on the current body of evidence that provide improved clinical usefulness and medical semantics. There will be a long and difficult task ahead, but it is time to get to work and try solving the DC/TMD conundrum for the advancement of our field and enhanced care for our patients. The field of orofacial pain and temporomandibular disorders is constantly evolving, and the need for patient-oriented, clinical-friendly classification systems that facilitate treatment plan is emerging.
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8. Load-bearing capacity and Weibull characteristics of inlay-retained fixed dental prosthesis: Effect of zirconia type, bonded substrate and aging.
PMID:日期:2026-09-24This study evaluated the load-bearing capacity and reliability of different zirconia materials used for inlay-retained fixed dental prostheses (IRFDPs), considering the influence of substrate type (tooth substrate or resin composite) and thermo-mechanical aging. IRFDPs (N = 160) were fabricated using four zirconia materials: IPS e.max ZirCAD LT (3Y-TZP), Katana YML (3Y-5Y graded zirconia), Katana HTML Plus, and Katana STML (n = 40 each). Restorations were adhesively cemented onto tooth or resin composite substrates and tested either under dry conditions or after thermo-mechanical aging (1,200,000 cycles, 50 N, 5-55 °C). Fracture load was determined using monotonic load-to-fracture testing. Data were analyzed using two-way ANOVA and Tukey's test (α = 0.05). Reliability of durability was assessed using Weibull analysis. Under dry conditions, material (p = 0.0047), substrate (p = 0.0237), and their interaction (p = 0.0004) significantly influenced fracture load. YML-composite (1406 ± 386 N) and HTML-composite (1142 ± 249 N) showed higher values than STML-composite (553 ± 246 N). No significant differences were observed on tooth. substrate After aging, material and interaction effects remained significant (p < 0.05). HTML-tooth showed the highest fracture load (1727 ± 351 N), while STML-composite showed the lowest (718 ± 292 N). Weibull analysis indicated comparable reliability after aging. Zirconia type and substrate significantly influenced mechanical performance of IRFDPs. High-translucent and graded zirconia showed substrate-dependent behavior, whereas 3Y zirconia was more stable. Zirconia selection and bonding substrate influence fracture resistance of IRFDPs. High-translucent zirconia requires careful substrate selection, while 3Y zirconia provides more consistent performance in posterior applications.
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9. Comparative evaluation of intraoral pH using different directives of sports drink and mouthguard among adolescents participating in contact sports.
PMID:日期:2026-09-24To evaluate and compare tooth surface pH and salivary pH at various time intervals using different directives of sports drink and mouthguard among adolescents involved in contact sports. This study involved 125 athletes aged 10-19 years, each provided with a mouthguard customized to their dentition. During a 40-minute physical activity session, participants consumed a sports drink either with or without water and with or without a mouthguard at 10-minute intervals. Salivary and tooth surface pH levels were recorded at baseline and at each break. The study was conducted over four consecutive weeks in four phases- Phase 1 (Sports drink without mouthguard), Phase 2 (Sports drink and water without mouthguard), Phase 3 (Sports drink with mouthguard), Phase 4 (Sports drink and water with mouthguard), altering the directives for sports drink consumption and mouthguard use. Data was analysed using Power BI and Python 3.11.4, with one-way ANOVA and Tukey's post hoc test for statistical comparisons. The results demonstrated that wearing a mouthguard helped maintain tooth surface and salivary pH stability when consuming sports drinks, with or without water. In contrast, without a mouthguard (phases 1 and 2), a significant pH drop was observed (p < 0.05), particularly at 20 and 30 min, though partial recovery occurred with water intake. The study underscores the dual role of mouthguards, that is, not only their well-established benefit in preventing dental trauma, as reported in previous studies, but also their potential function as a protective barrier against acid-induced enamel demineralization. However, further well-designed studies are required to confirm and substantiate these beneficial effects of mouthguard use. The findings of this study provide clear guidelines for the safe consumption of sports drinks among adolescent athletes, while also emphasizing the dual role of mouthguards in preventing both dental trauma and the erosive effects of these beverages. CTRI/2023/10/058189.