JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY临床与实验神经心理学杂志
JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY(英文缩写 J CLIN EXP NEUROPSYC),ISSN 1380-3395,eISSN 1744-411X,中文译名:临床与实验神经心理学杂志 是一本学术期刊。本页汇总该期刊的最新影响因子、分区信息以及最新收录于 PubMed 的文献,帮助您快速了解期刊全貌。
发文量统计区间：2025-10-01 至 2026-09-30，按本站收录文献的发表日期统计。
期刊介绍
历年影响因子趋势
| JCR 数据年份 | 影响因子 | JCR 分区 |
|---|---|---|
| 2021 | 2.283 | Q3 |
| 2022 | 2.200 | Q3 |
| 2023 | 1.800 | Q3 |
| 2024 | 1.700 | Q3 |
| 2025 | 2.000 | Q2 |
JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY 最新收录文献
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1. Depression, not stroke, is associated with greater expressive suppression while emotion identification is preserved.
PMID:日期:2026-10-04Stroke is followed both by frequent depression and by reported alterations in emotional processing, yet these are rarely examined jointly, leaving it unclear whether emotional disturbances reflect the lesion or the concurrent depression. We aimed to separate the contributions of depression and of mild right-hemisphere stroke to two distinct components of socioemotional functioning: habitual emotion regulation and facial emotion identification. Sixty adults were studied in a 2 × 2 design crossing Stroke (survivors of mild right-hemisphere ischemic stroke with complete functional recovery, modified Rankin Scale = 0, vs. stroke-free) and Depression (clinically diagnosed vs. absent). Habitual regulation was assessed with the Emotion Regulation Questionnaire (cognitive reappraisal, expressive suppression) and identification with a six-emotion forced-choice task. Data were analyzed with factorial analyses of variance, with covariate-adjusted and non-parametric confirmation, and with a dimensional analysis relating depressive symptom severity to each outcome. Depression, not stroke, was the principal correlate of habitual regulation. Participants with depression reported greater expressive suppression than those without (F = 7.50, = .008, partial η = .12; Cohen's d = 0.74), independently of stroke and robust to adjustment for age and cognition. The parallel effect on reappraisal was directionally consistent but non-significant. Dimensionally, symptom severity correlated with suppression only. Facial emotion identification was preserved and did not differ across groups, with no Stroke × Depression interaction on any outcome. Stroke effects that were large in our earlier, less fully recovered sample were absent here. In well-recovered right-hemisphere stroke, depressive status rather than the lesion was associated with greater habitual reliance on expressive suppression, whereas emotion identification was intact. When emotional difficulties arise in such patients, concurrent depression rather than the lesion may warrant primary clinical attention. Given the modest sample and absence of lesion imaging, findings are provisional and require severity-stratified, imaging-informed replication.
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2. Executive functions are independently associated with health-related numeracy and self-perceived health literacy in applied contexts in healthy adults.
PMID:日期:2026-10-04Over a third of U.S. adults struggle with health literacy, which broadly describes the ability to access, understand, and use health-related information. Conceptual models highlight the importance of cognitive functions in health literacy, but limited empirical work has carefully examined the extent to which various aspects of cognition uniquely contribute to different dimensions of health literacy. Participants in this retrospective, harmonized study included 312 healthy adults who completed a battery of well-validated cognitive tests that measured their general fund of knowledge, attention, declarative memory, and executive functions (;). Participants also completed a performance-based measure of health-related numeracy (i.e., Expanded Numeracy Scale) and questionnaires assessing self-perceived health literacy in applied contexts (i.e., Brief Health Literacy Screening and eHealth Literacy Scale). After accounting for the influence of sociodemographics and general fund of knowledge parallel hierarchical regressions showed that measures of executive functions and memory explained a significant amount of variance in health-related numeracy and measures of executive functions explained a significant, but modest, amount of variance in self-perceived health literacy in applied contexts after accounting for the influence of sociodemographics and general fund of knowledge. Findings suggest that executive functions (i.e. generativity and cognitive flexibility) play a unique role in some aspects of personal health literacy among healthy adults. Future experimental studies might further dissect the role of executive functions in the expression and management of health literacy in at-risk clinical populations.
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3. Dot counting test time and errors in U.S. veterans.
PMID:日期:2026-09-21Prior studies have explored potential improvements to the Dot Counting Test's efficiency at detecting invalid neuropsychological performance. The present study examined the classification accuracy and clinical utility of typical scoring (E-score), total response time, error scores, and two abbreviated versions. United States military veterans within the VA healthcare system, n=137, mean age=39.1 (SD=9.0), were administered a battery of neuropsychological tests including the DCT and seven other performance validity tests. These veterans were referred for current cognitive complaints in the context of a reported history of head injury and were OIF/OEF/OND era veterans evaluated between 2016 and 2023. . Sensitivity and specificity at various cutoff scores were calculated for all variables. The highest classification accuracy at an optimal specificity level was found for the full DCT time score and the DCT-6 time score (for both, sensitivity = 64.3, specificity = 92.6). While the classification accuracy for the E-score was strong, accuracy of the total time score and DCT6 time score were slightly better in this sample. The advantage of time-only scores was demonstrated in this study while the inclusion of error count in DCT score was shown to have a negligible benefit to classification accuracy. All DCT indices evaluated herein, E-scores and time-only scores for the full test and abbreviated forms, demonstrated effective classification accuracy and are supported for use in evaluations with younger veterans and similar clinical populations.
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4. Recognition memory as a neuropsychological marker of progression in early-stage Alzheimer's disease: a 24-month prospective cohort study.
PMID:日期:2026-09-16Alzheimer's disease (AD) is the leading cause of dementia, and amnestic mild cognitive impairment (a-MCI) is considered its prodromal stage. Recognition memory is commonly assessed with yes/no tasks, although conventional scoring often overlook false alarms. Signal Detection Theory (SDT) measures, particularly discriminability (d-prime), may better detect early recognition deficits and predict progression to AD dementia. In this prospective cohort study, 278 older adults with a-MCI were followed for 24 months. Participants underwent clinical and neuropsychological assessment, including the Rey Auditory Verbal Learning Test. Recognition was decomposed into hits, false alarms, and d-prime. A subsample underwent amyloid and tau biomarker assessment by cerebrospinal fluid and/or imaging. Mixed-effects models examined longitudinal change and prediction of conversion to AD dementia. Delayed recall, recognition hits, and d-prime declined significantly over time, with steeper trajectories among converters. Converters showed an early and marked d'prime reduction during the first 12 months, mainly related to increased false alarms. Lower baseline d-prime and greater early decline independently predicted conversion after adjustment for demographic, global cognition, and AD biomarkers. SDT-derived recognition indices, especially d'prime, provide clinically relevant prognostic information in a-MCI. Adding d' to delayed recall and biomarkers may improve risk stratification, follow-up planning, and selection for disease-modifying trials.
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5. Cross-sectional relationships between memory scores and neurodegeneration biomarkers in patients with suspected cognitive impairment.
PMID:日期:2026-09-08We aimed to examine whether additional metrics derived from the CERAD Word List Memory Test (WLMT) such as acquisition patterns, error frequencies, and consolidation efficiency, are associated with cerebrospinal fluid (CSF) biomarkers of amyloid and tau pathology, as well as magnetic resonance imaging (MRI) ratings of brain atrophy and small vessel disease, in individuals with suspected cognitive impairment who nonetheless perform within normative ranges on the traditional WLMT measures. We included 109 patients from a memory clinic setting (46% female, median age 69.5 years, 55.1% with normal AD biomarkers, 25.7% in the AD continuum) that underwent comprehensive neuropsychological assessment, CSF biomarker analysis, and visual MRI rating. Associations between traditional and additional memory scores and the biomarkers were examined using regression analyses, controlling for demographic variables and adjusting for multiple comparisons. Correlations were modest and partly mediated by demographics. Traditional scores showed the strongest links, but additional scores "lost access" and "learning ratio" were also associated with lower Aβ CSF levels (ρ = -.23, = .034) and medial‑temporal lobe atrophy (e.g. learning ratio, ρ = -.30, = .036), suggesting sensitivity to subtle learning‑consolidation inefficiencies. High burden of white matter hyperintensities was associated with intrusion errors (U = 807.5, < .05, d' = 0.23) and less stable learning (U = 613.0, < .01, d' = 0.41). Both traditional and additional memory scores can assist early detection and risk stratification of neurodegenerative disease in patients with normative performance, but these findings require replication in larger, more heterogeneous cohorts.
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6. Validation and interpretation of the Persian Multiple Sclerosis Neuropsychological Screening Questionnaire.
PMID:日期:2026-09-08Cognitive impairment affects between 50 and 60% of people with multiple sclerosis (PwMS). Cognitive impairment usually includes problems with memory, speed of processing information, learning, and executive functions. This can impact everyday activities and quality of life. The Multiple Sclerosis Neuropsychological Screening Questionnaire (MSNQ) is a short and easy-to-use tool for patients that helps patients report perceived cognitive difficulties. The objective of this study was to validate the Persian of patient-reported MSNQ (MSNQ-P). The study included 140 Persian-speaking PwMS, with a mean age of 37.9 years and predominantly female (90%). Exploratory factor analysis (EFA) was utilized to analyze the MSNQ-P's factor structure. Internal consistency was assessed through Cronbach's alpha and test-retest reliability was evaluated with intraclass correlation coefficient (ICC). Convergent validity was evaluated by correlating the MSNQ-P with the Symbol Digit Modalities Test (SDMT). EFA confirmed that the MSNQ-P is unidimensional after excluding one item, leading to a 14-item version with strong factor loadings. The 15-item MSNQ-P demonstrated high internal consistency (Cronbach's alpha = 0.934), which improved after item reduction (Cronbach's alpha = 0.940). The test-retest reliability showed excellent results (ICC = 0.990). The 14-item MSNQ-P was correlated with SDMT ( = -0.585, -value < 0.001), Beck Anxiety Inventory (BAI) ( = 0.358, -value < 0.001), and Beck Depression Inventory-II (BDI-II) ( = 0.593, -value < 0.001), supporting the tool's convergent validity. This study highlights the validity and reliability of the Persian 14-item MSNQ-P for assessing cognitive impairments in PwMS.
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7. Examining reaction time variables to detect invalid performance on the TOMM 2: comparing mTBI to simulators using two procedures.
PMID:日期:2026-09-07Two studies are presented involving simulator designs to investigate the utility of reaction time (RT) indices from the first two trials of the computerized TOMM 2. A sample of largely mild traumatic brain injuries (TBI) was compared to simulators whose correct responding was below the traditional passing score of 45/50 but not significantly below chance. In Study 1, 47 healthy participants were presented a scenario in which they were given the to malinger for financial compensation; a procedure that more closely parallels real-world settings where individuals are incentivized to malinger but are not explicitly instructed to do so. Reaction time indices for those who chose to simulate were compared to 30 individuals who experienced a diagnosed TBI. Both the Coefficient of Variation (CoV) of RT and the standard deviation of RT for Trial 2 differentiated simulators from those with TBIs. In Study 2, 69 individuals were explicitly instructed to feign in a more traditional simulator design and compared on the TOMM 2 reaction time indices. The findings from Study 1 were replicated, showing both standard deviation and CoV of RT in Trial 2 differentiated between TBIs and simulators, and the effect size for the CoV of RT was larger. Classification statistics were maximized using a base rate of 40%. The present findings provide preliminary evidence for the utility of the TOMM 2 reaction time measures in detecting subnormal performance, especially when respondents score below the typical passing score of 45, but do not score significantly below chance on the performance validity test.
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8. Can lexical properties of words produced on a semantic fluency task distinguish older adults with cognitive decline from older adults with stable cognitive scores?
PMID:日期:2026-08-28Deficits in semantic fluency are commonly observed across many types of dementia. However, deficits in semantic fluency are not always representative of a decline in language skills. Prior studies have suggested that the examination of the lexical properties of words produced on semantic fluency tasks may reveal disruptions in discrete cognitive processes that could assist in the detection of specific types of dementia. The mean word frequency, age of acquisition, and phonological neighborhood size of items generated on a semantic fluency task (fruits and vegetables) were compared between a sample of individuals with mild cognitive impairment or dementia (cognitively impaired, = 65) and a sample of healthy older adults with normal cognition who were cognitively stable over an average of 5 years following initial assessment (cognitively stable, = 72). Relations of these variables to scores on tests of language, executive functioning, and processing speed were also explored. After controlling for age and education, the cognitively impaired group produced words of higher mean word frequency and lower mean age of acquisition than the cognitively stable group. Mean phonological neighborhood displayed the opposite pattern to expectations, with the cognitively stable group generating words with more phonological neighbors. Relations of evaluated word properties to tests of varied cognitive domains were explored in the overall sample, with mixed results. Word properties of items generated on a semantic fluency task differed between cognitively impaired and cognitively stable groups. Future studies should investigate word properties of semantic fluency responses in the context of severity of cognitive impairment, thoroughly examine susceptibility to sociocultural factors, evaluate if findings are consistent across semantic fluency tasks, and explore ability to offer incremental validity for differential diagnosis and early detection over total scores alone.
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9. Alternative forms of the parametric Go/No-Go task: development and comparison.
PMID:日期:2026-08-24The Parametric Go/No-Go (PGNG) task assesses cognitive domains, including executive functioning and processing speed, within three difficulty levels. The PGNG task was originally developed for clinical and research assessments, in only one version (using target consonants, XYZ). The study aims to develop six alternative tri-consonant forms of the preexistent form and to test their equality. We hypothesized performance differences between each difficulty level of a given PGNG version, and that, in contrast, all the tri-consonant alternate versions would be equivalent in performance. A total of 349 participants were recruited online to complete one of seven task versions - each a unique tri-consonant variation with three difficulty levels. The dependent variables measured were Percentage of Correct Target (PCT), Percentage of Correct Inhibition (PCI), Efficiency, Response Time (RT), and Response Time Coefficient of Variation (RTCoV). For each version, we found level 1 to be the most challenging compared to level 2, and level 3 to be the most challenging, with the lowest accuracy and the longest response time. No differences were found in RTCoV measure across any of the tri-consonant versions. However, differences between tri-consonant versions were observed depending on the specific performance measures and levels of the PGNG. As expected, there were differences between difficulty levels on all measures and versions, with performances being globally different in levels 1, 2, and 3. The overall results showed that all the tri-consonant versions were similar on temporal measures (RT and RTCoV). Four tri-consonant versions (XYZ, BCM, NPV, and RST) were similar in terms of performance on all five performance measures. The observed differences are discussed through Baddeley's model of working memory and the implication of multisensory information.
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10. Age at menopause and subjective cognitive symptoms predict digital cognitive outcomes at the gynecological Well-Woman visit.
PMID:日期:2026-08-19Women are at increased risk for Alzheimer's Disease (AD). Growing evidence suggests that the menopausal transition may represent a vulnerable window for development of AD-related pathology. Yet, women are diagnosed with AD later than men. Conducting routine cognitive screenings and integrating information about both cognitive symptoms and age at menopause may help address sex-based disparities in detection and prevention. This study investigated whether subjective cognitive symptoms, in combination with age at menopause, were associated with performance on a digital cognitive task in postmenopausal women. 183 postmenopausal women (mean age = 63.8, range = 45-85) were recruited after their Well-Woman visit. Participants completed the Screener for Cognitive Problems in Everyday Life (SCoPE) to assess subjective cognitive symptoms, followed by a sensitive measure of objective cognition: the Linus Health Digital Clock and Recall (DCR™). Information was also collected on age at menopause. We examined associations of subjective cognitive symptoms and age at menopause with digital cognitive performance, adjusting for age, education and depression. Model fit was evaluated using adjusted R, AIC, and BIC. 48.1% of women reported one or more cognitive symptoms on the SCoPE. On objective testing, 73.2% scored in the normal range, 20.8% in the borderline range, and 6.0% in the impaired range. SCoPE total score was negatively associated with objective cognitive performance in adjusted models (B = -.12, = .03). Age at menopause showed a significant quadratic association with cognitive performance (B = -0.006, <.001). SCoPE total was not associated with DCR subtests, while age at menopause predicted both Delayed Recall and Clock Drawing. Subjective cognitive symptoms and age at menopause were associated with lower performance on a sensitive, objective cognitive test. Findings support routine cognitive screening and suggest that subjective cognitive symptoms as well as age at menopause are associated with cognitive function.