FOLIA PARASITOLOGICA寄生虫学文集
FOLIA PARASITOLOGICA(英文缩写 FOLIA PARASIT),ISSN 0015-5683,eISSN 1803-6465,中文译名:寄生虫学文集 是一本学术期刊。本页汇总该期刊的最新影响因子、分区信息以及最新收录于 PubMed 的文献,帮助您快速了解期刊全貌。
发文量统计区间：2025-11-01 至 2026-10-31，按本站收录文献的发表日期统计。
期刊介绍
历年影响因子趋势
| JCR 数据年份 | 影响因子 | JCR 分区 |
|---|---|---|
| 2021 | 1.614 | Q3 |
| 2022 | 1.600 | Q3 |
| 2023 | 1.500 | Q3 |
| 2024 | 1.600 | Q3 |
| 2025 | 2.000 | Q3 |
FOLIA PARASITOLOGICA 最新收录文献
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1. Identificaton of novel Cystoisospora suis enolase 2 interaction proteins in IPEC-J2 cells using Co-IP/LC-MS.
1. 使用Co-IP/LC-MS鉴定IPEC-J2细胞中新型猪囊尾蚴烯醇化酶2相互作用蛋白PMID:日期:2026-08-31Enolase 2 (ENO2) is a crucial an important glycolytic enzyme involved in glycolysis and is also recognised as a multifunctional protein. However, its interacting proteins in intestinal porcine epithelial cells (IPEC-J2 cells) remain unclear. This study investigates the interacting proteins of Cystoisospora suis (Biester et Murray, 1934) ENO2 (CsENO2) in IPEC-J2 cells. According to our previous research, CsENO2 is highly expressed in sporulated oocysts. Co-immunoprecipitation/liquid chromatography-mass spectrometry (Co-IP/LC-MS) was conducted using the pcDNA3.1-Flag vector carrying the enolase 2 gene, which was transfected into IPEC-J2 cells to co-immunoprecipitate with cellular proteins. The Co-IP/LC-MS-based protein sequencing identified three cellular proteins: NME2, RPS3, and Vimentin. Subsequently, cDNAs encoding the complete coding sequences of these proteins were cloned into the pGEX-4T-1 expression vector. Immunofluorescence assays revealed the localisation of CsENO2 in sporulated oocysts and sporozoites. Most CsENO2 protein was found in the cytoplasm of sporulated oocysts. In sporozoites, CsENO2 protein was primarily distributed around and outside the nucleus. This study aims to identify CsENO2-interacting proteins in IPEC-J2 cells and determine the localisation of CsENO2 within sporulated oocysts and sporozoites.
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2. A new genus and three new species of tapeworms (Cestoda: Onchoproteocephalidea) in Erythrolamprus snakes (Colubridae: Dipsadinae) in South America.
2. 南美洲红斑蛇（Colubidae：Dipsadinae）中绦虫的一个新属和三个新种（Cestoda：Onchoproteocephalidea）PMID:日期:2026-08-26The species diversity of reptile parasites in the New World, including South America, remains poorly understood, and this also applies to tapeworms (Cestoda: Onchoproteocephalidea). Only 17 species of the non-monophyletic genus Ophiotaenia La Rue, 1911 have been recorded in reptiles in the Neotropical Region. In this paper, three new species are described from dipsadine snakes of the genus Erythrolamprus Boie (Colubridae) in Brazil and Paraguay, and a new genus, Penetrocestus, is proposed to accommodate these tapeworms that penetrate the intestinal wall of their hosts. The new genus differs from other proteocephalids parasitising snakes by the presence of a large apical glandular organ, which is larger than the suckers, and a large vaginal sphincter lined with a thick layer of chromophilic cells. Penetrocestus gen. n. is also characterised by a long and wide region ('metascolex') posterior to the scolex and a well-developed inner longitudinal musculature, which is weakly developed in most proteocephalids parasitising Neotropical snakes. Ophiotaenia joanae (de Chambrier et Paulino, 1997) from Xenodon neuwiedii Günther (Colubridae) in Brazil is transferred to Penetrocestus as its type species and as a new combination. Penetrocestus gorgonae sp. n. from Erythrolamprus aesculapii (Linnaeus) in Brazil, Penetrocestus jaegeri sp. n. from Erythrolamprus jaegeri (Günther) in Paraguay, and Penetrocestus tristani sp. n. from Erythrolamprus poecilogyrus (Wied-Neuwied) in Paraguay differ from Penetrocestus joanae (de Chambrier et Paulino, 1997) comb. n. and from each other by the position of the metascolex, width of the scolex, morphology of the terminal (distal) portion of the vagina, and the number of testes, as summarised in the key to their identification. The phylogenetic relationships of the new species are unknown, as they were collected more than 35 years ago and no tissues were fixed in ethanol for genetic characterisation, but the new data support the assumption of strict host specificity of reptilian tapeworms in the Neotropical Region.
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3. Host switching via rare sex: Oncorhynchus mykiss as a vector in fusion of three Gyrodactylus salaris genomes into a sexual-clonal population on a landlocked Salmo salar (Monogenea, Platyhelminthes).
3. 通过罕见的有性生殖实现宿主转换：虹鳟作为载体，将三个鲑鱼三代虫基因组融合到内陆大西洋鲑（单殖吸虫纲，扁形动物门）上的有性-克隆种群中PMID:日期:2026-08-03The monogenean ectoparasite Gyrodactylus salaris Malmberg, 1957 was detected in 2001 on juveniles of landlocked Salmo salar Linnaeus in three rivers draining to Lake Kuitozero in the White Sea basin. The ancestry of the colony was studied by internal transcribed spacers of the nuclear ribosomal operon (ITS), mitochondrial COI gene and by 12 microsatellite markers. The maternal ancestor was a frozen heterozygotic and heteroplasmic diploid clone RBT marked by a ITS-1068, spread by rainbow trout and observed in Denmark, Norway, Finland and Russia. The clone combined genomes from two divergent matrilines, probably from grayling (Thymallus Linck) in the Southern Baltic basin (COI , 84 % bootstrap support) and in Balkans (COI , 99 %). The genetic distance of the 1545 bp sequences was dMCL = 0.025. The population in Kuitozero was a progeny of RBT females repeatedly inseminated by conspecific males. It was sexual but propagated as parthenogenetic clones. The derived population carried only COI . The microsatellite alleles of the RBT clone segregated with the paternal alleles following Mendelian model, with an excess of heterozygotes: He = 0.608, Ho = 0.883. Among 244 genotyped worms, 27 multilocus clones were observed, as segregated among the parr (FST = 0.824). Parental genotypes were not detected. The largest clone (104 worms) was heterozygotic in all 12 loci and was identified on fifteen fish, in two rivers and four years. The balancing selection (excess of heterozygotes) equalised the allelic frequencies and maximised the genetic variance available for purifying and adaptive natural selection on a new host. The two sexual episodes associated with three host switch steps offers a model to understand the evolution of the diverse host spectrum of host-specific Gyrodactylus von Nordmann, 1832.
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4. Special Issue: Does latent Toxoplasma infection mimic the immune profile of schizophrenia? Sex-specific cytokine and brain-marker alterations suggest partial overlap.
4. 专刊：潜伏性弓形虫感染是否模拟精神分裂症的免疫特征？性别特异性的细胞因子和脑标志物改变提示部分重叠PMID:日期:2026-06-25[中文摘要] 精神分裂症常伴有低度神经炎症。由于潜伏性弓形虫病（LT）在精神分裂症个体中更为普遍，我们检验了LT是否会产生一种与精神分裂症中所报道的生物标志物模式相似的标志物模式。我们使用多重免疫分析方法，对65名LT阳性个体和103名匹配的LT阴性对照者定量了15种细胞因子和15种脑损伤血液标志物。通过MANCOVA和PERMANOVA评估感染、年龄、性别及其交互作用的多变量效应。通过偏Kendall相关（控制年龄和性别）检验对单个生物标志物的效应。通过对由偏相关得出的相异性矩阵进行Mantel检验，评估内部相关结构的差异。LT与较高的KLK6、S100B和TDP-43以及较低的MIF相关；其他若干标志物显示出非显著但幅度可观的趋势。感染组的细胞因子显示IFN-γ、IL-1β和MCP-1降低，IL-13和IL-17升高。性别分层分析提示，对脑损伤标志物的效应在女性中更强，而对细胞因子的效应在男性中更强。相关结构也出现分化：感染者脑损伤标志物与细胞因子之间表现出更多负相关，而对照组主要呈正相关（Mantel r = 0.461，p = 0.043）。LT特征与精神分裂症在KLK6和S100B升高方面重叠，在男性中还表现为GDNF降低，但在MIF以及总体细胞因子模式方面形成对比（无一致的IL-6/TNF-α升高）。LT引起神经炎症和神经免疫改变，这些改变仅部分重现精神分裂症；其生物标志物模式及相互关系不同，这反对将LT视为精神分裂症相关神经炎症的主要驱动因素。
[英文摘要] Schizophrenia often features low-grade neuroinflammation. Because latent toxoplasmosis (LT) is more prevalent among individuals with schizophrenia, we tested whether LT yields a biomarker pattern resembling that reported in schizophrenia. We quantified 15 cytokines and 15 blood markers of brain injury in 65 LT-positive individuals and 103 matched LT-negative controls using multiplex immunoassays. Multivariate effects of infection, age, sex, and their interaction were assessed by MANCOVA and PERMANOVA. Effects on individual biomarkers were tested by partial Kendall correlation (controlling for age and sex). Differences in the internal correlation structure were evaluated with Mantel tests on dissimilarity matrices derived from partial correlations. LT was associated with higher KLK6, S100B, and TDP-43, and lower MIF; several other markers showed nonsignificant but sizable trends. Cytokines showed reduced IFN-γ, IL-1β, and MCP-1, and elevated IL-13 and IL-17 in the infected group. Sex-stratified analyses suggested stronger effects on brain-injury markers in women and on cytokines in men. Correlation structure also diverged: infected individuals exhibited more negative links between brain-injury markers and cytokines, whereas controls showed predominantly positive associations (Mantel r = 0.461, p = 0.043). The LT profile overlapped with schizophrenia in elevated KLK6 and S100B and, in men, reduced GDNF, but contrasted for MIF and for the overall cytokine pattern (no consistent IL-6/TNF-α elevation). LT entails neuroinflammatory and neuroimmune alterations that only partly recapitulate schizophrenia; the biomarker pattern and interrelationships differ, arguing against LT as the main driver of schizophrenia-related neuroinflammation.
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5. Lack of evidence for the presence of plastids in the evolutionary history of kinetoplastid protists.
5. 缺乏证据表明在动质体原生动物的进化历史中存在质体PMID:日期:2026-06-10The discovery of multiple metabolic enzymes encoded by genes of apparent plant or cyanobacterial origin in trypanosomatids led to the influential hypothesis that the common ancestor of Euglenozoa harboured a plastid that was subsequently lost in kinetoplastids. Here, we critically re-evaluate this hypothesis using an expanded, phylogenetically balanced dataset comprising 299 eukaryotic and 102 bacterial species. We reassess the evolutionary histories of 16 genes encoding proteins previously interpreted as evidence for an ancestral euglenozoan plastid using state-of-the-art maximum-likelihood and Bayesian phylogenetic approaches, supplemented by topology tests. Our analyses reveal that none of the examined genes provides compelling support for a plastid-bearing ancestor of Euglenozoa. Instead, these enzymes display heterogeneous evolutionary origins consistent with multiple independent horizontal gene transfer events between euglenozoans and diverse bacterial (distinct from cyanobacteria) and eukaryotic donors. Only the gene encoding a vacuolar H⁺-pyrophosphatase, an electrogenic proton pump, shows limited affinity to chloroplast-bearing lineages, and this signal alone is insufficient to infer plastid ancestry. Taken together, our results strongly suggest a horizontal gene transfer from various non-plastid bearing lineages over the hypothesis of plastid presence in the euglenozoan common ancestor with subsequent loss in kinetoplastids, diplonemids, and non-photosynthetic euglenids.
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6. Temporal dynamics of parasite community in the three-spot cichlid Amphilophus trimaculatus from Tres Palos Lagoon, Guerrero, Mexico.
6. 墨西哥格雷罗州Tres Palos泻湖三斑慈鲷寄生虫群落的时间动态PMID:日期:2026-05-14The temporal dynamics of parasite communities of the Three-spot cichlid Amphilophus trimaculatus Günther 1867 was examined during an annual cycle. A total of 770 fishes were collected between March 2019 and February 2020 from a tropical costal lagoon. Thirteen taxa of metazoan parasites were identified, two of monoxenous and 11 of heteroxenous parasites. No significant changes were observed in the species composition of parasite communities in A. trimaculatus during a 12-yr period (2008-2020). The prevalence of infection of six heteroxenous parasites Austrodiplostomum ostrowskiae Dronen, 2009, Cladocystis cf. trifolium Poche, 1926, Clinostomum cf. tataxumui Sereno-Uribe, Pinacho-Pinacho, García-Varela et Pérez-Ponce de León, 2013, Crassicutis cichlasomae Manter, 1936, Southwellina cf. hispida Witenberg, 1932 and Contracaecum sp. varied between sampling months, and/or climatic seasons. Some species were more prevalent during some months of the dry season, while others during the rainy season, suggesting that these parasite populations respond differently to environmental changes. The environmental changes generated by the dry/rainy cycle may have affected the availability of intermediate host populations, and the feeding and reproductive behaviour of the host. Temporal variations in the infection levels of some parasite species generated important changes in the structure of the component communities over time. This study allows us to appreciate the sensitivity of parasite-host systems to environmental variability, and suggests that alterations to hydrological regimes could have significant consequences on parasite biodiversity in tropical brackish water environments.
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7. First report of adults of Acanthocephaloides irregularis from cuttlefish Sepia officinalis (Cephalopoda) in Tunisia: SEM observations and molecular analysis.
7. 突尼斯墨鱼（头足类）不规则棘突蛛成虫的首次报道：SEM观察和分子分析PMID:日期:2026-04-30[中文摘要] 在对采集自突尼斯北部比塞大潟湖的普通乌贼（Sepia officinalis，Linnaeus）进行寄生虫学调查期间，发现成虫期棘头虫附着于乌贼胃内壁。鉴于这些专性内寄生虫的终末宿主通常为脊椎动物，在头足类中发现成虫期棘头虫实属罕见。利用光学显微镜和扫描电子显微镜对雌雄虫体进行详细形态学检查，结果显示其与Acanthocephaloides irregularis Amin, Oğuz, Heckmann, Tepe et Kvach, 2011具有高度形态相似性。成功获得了细胞色素氧化酶亚基I（COI）基因604 bp的部分序列。基于COI基因的系统发育分析证实了该鉴定结果，显示突尼斯A. irregularis分离株与来自Gobius bucchichii Steindachner的A. propinquus（Dujardin, 1845）聚类关系密切。本研究首次记录了地中海海域S. officinalis中A. irregularis的感染，为其生活史、宿主特异性及在底栖食物网中的生态学意义提供了新见解。这一发现提出了关于头足类宿主在海洋环境中棘头虫传播动力学中所起作用的重要问题。
[英文摘要] During a parasitological survey of the common cuttlefish Sepia officinalis (Linnaeus) collected from the Bizerte Lagoon in northern Tunisia, adult acanthocephalans were found attached to the internal wall of cuttlefish stomach. The presence of adult acanthocephalans in cephalopods is unusual, given that definitive hosts for these obligate endoparasites are typically vertebrates. A detailed morphological examination of both sexes using light and scanning electron microscopy revealed high morphological similarities to Acanthocephaloides irregularis Amin, Oğuz, Heckmann, Tepe et Kvach, 2011. A partial sequence of 604 bp of the cytochrome oxidase subunit I (COI) gene was successfully generated. Phylogenetic analysis based on COI gene confirmed the identification, showing that the Tunisian isolate of A. irregularis clustered closely to A. propinquus (Dujardin, 1845) from Gobius bucchichii Steindachner. This study presents the first record of A. irregularis in S. officinalis in the Mediterranean Sea, offering new insights into its life cycle, host specificity, and ecological significance within benthic food webs. This finding raises important questions about the role of cephalopod hosts in the transmission dynamics of acanthocephalans in marine environments.
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8. Description of Ophthalmonema diodontis gen. et sp. n. (Nematoda: Cystidicolidae), a parasite of the eye and surrouding tissues of porcupinefishes (Diodon spp.), with a key to cystidicolid genera.
8. 眼虫diodontis gen.et sp.n.（线虫：囊尾蚴科）的描述，这是一种豪猪（Diodon spp.）眼睛和周围组织的寄生虫，是囊尾蚴属的关键PMID:日期:2026-04-23[中文摘要] 建立了一个新的线虫属和种，眼线虫属双齿种（Ophthalmonema diodontis gen. et sp. n.）（囊线虫科），基于从一尾水族箱饲养的斑点鳍刺豚鱼（Diodon hystrix Linnaeus，刺豚科，鲀形目）双眼采集的雌性标本（雄性未知），该鱼最初捕获于美国佛罗里达州沿海水域。通过光学显微镜和扫描电子显微镜检查发现，该线虫的口部结构，特别是存在两块显著大、圆形、相对的背腹板，每块板通过一条窄桥与假唇的内端相连，在所有囊线虫科属中是独特的。此前分别从加勒比海和澳大利亚南部水域的D. hystrix和Diodon nicthemerus Cuvier眼部及周围组织报道的描述不充分的囊线虫科线虫，被鉴定为Metabronema sp.或囊线虫科未定属种，现被认为属于新种O. diodontis。提供了囊线虫科属的检索表。
[英文摘要] A new nematode genus and species, Ophthalmonema diodontis gen. et sp. n. (Cystidicolidae), are established based on female specimens (males remain unknown) collected from both eyes of an aquarium-kept spot-fin porcupinefish, Diodon hystrix Linnaeus (Diodontidae, Tetraodontiformes), originally caught in coastal waters off Florida, USA. Examination by light (LM) and scanning electron microscopy (SEM) revealed that the mouth structure of this nematode, particularly the presence of two conspicuously large, rounded, opposing dorsoventral plates, each connected by a narrow bridge to the inner end of the pseudolabium, is unique among all cystidicolid genera. Inadequately described cystidicolid nematodes previously reported from the eye and surrounding tissues of D. hystrix and Diodon nicthemerus Cuvier in the Caribbean Sea and in waters off southern Australia, respectively, as Metabronema sp. or Cystidicolidae gen. sp. are considered to belong to the new species O. diodontis. A key to cystidicolid genera is provided.
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9. Three decades of research on molecular genetic characteristics of Echinococcus spp.: a bibliometric study.
9. 棘球属物种分子遗传特征研究三十年：一项文献计量学研究PMID:日期:2026-02-24Research on the molecular genetics of Echinococcus has advanced significantly owing to its relevance in understanding genetic variation, host-parasite interactions, and the transmission of Echinococcus species. A bibliometric analysis was performed using RStudio (Bibliometrix) and VOSviewer to evaluate molecular genetic research on Echinococcus spp. published between 1985 and 2025. Data were extracted from Scopus, Web of Science, PubMed, Europe PMC, and ProQuest. The analysis revealed a steady rise in publications on Echinococcus molecular genetics, accelerating from the early 2000s and peaking around 2017, with a slight decline after 2023, reflecting fluctuations in research activity. Comparative analysis showed Echinococcus consistently surpassed Schistosoma, Taenia, and soil-transmitted helminths, peaking at 60 articles in 2020-2021. Early publications achieved high mean Total Citations (TC) per year, followed by a stable trend, indicating lasting impact. Leading journals included Parasitology Research (Germany; 70 articles, H-index 114), Veterinary Parasitology (Netherlands; 62, H-index 150), Parasitology (UK; 53, H-index 173), Acta Tropica (Netherlands; 34, H-index 122), and PLOS Neglected Tropical Diseases (USA; 28, H-index 172). Tehran University of Medical Sciences (54 articles) led institutions. Influential authors included D. P. McManus and T. Romig. Multinational studies (484 publications) had higher citations than single-country (474). Iran (121), China (116), and Italy (53) led global contributions, emphasising collaboration, genotyping, phylogeny, and veterinary applications. This bibliometric study underscores the evolving trends in Echinococcus molecular genetics, providing valuable insights for researchers and stakeholders to guide future investigations and collaborative strategies in controlling echinococcosis.
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10. Harmless parasites? Infections with Hemolivia mauritanica (Apicomplexa: Adeleorina: Karyolysidae) and Haemocystidium spp. (Apicomplexa: Haemosporida: Haemoproteidae) have a negligible impact on white cell counts in tortoise hosts.
10. 无害的寄生虫？ Mauritanian血寄生虫（顶复门：Adeleorina目：Karyolysidae科）和血囊虫属（顶复门：血孢子虫目：血变形虫科）的感染对陆龟宿主的白细胞计数影响微乎其微PMID:日期:2025-11-28The pathogenicity of haemogregarines and their effects on the health status of ectothermic hosts remain largely unexplored. In this study, we examined the impact of Hemolivia mauritanica (Sergent et Sergent, 1904) infection on the differential leukocyte count (DLC) as a measurable indicator of health in tortoise hosts. A total of 206 blood smears were analysed, including 181 from spur-thighed tortoises (Testudo graeca Linnaeus) and 25 from marginated tortoises (Testudo marginata Schoepff). Light microscopy was used to identify infected individuals, determine DLC, and quantify parasitaemia levels. Overall, H. mauritanica was detected in 125 of 181 (69%) T. graeca samples and 21 of 25 (84%) T. marginata samples. To assess whether infection influenced DLC, we statistically compared leukocyte profiles between infected and uninfected individuals. Additionally, we evaluated the effects of other factors, including host species, parasitaemia intensity, sex, age, and the month and year of blood collection. Wilcoxon rank-sum tests revealed that parasitaemia and age had a statistically significant effect on DLC in T. graeca. Further analysis using linear models showed a significant association between parasitaemia and DLC, specifically affecting azurophils in T. graeca and basophils in T. marginata. Nine T. graeca tortoises positive for H. mauritanica were co-infected with haemosporidian parasites of the genus Haemocystidium Castellani et Willey, 1904, specifically three with Haemocystidium anatolicum (Orkun et Güven, 2013) and six with Haemocystidium caucasicum (Krasilnikov, 1965). Although co-infection itself was not statistically significant, a separate analysis of Haemocystidium parasitaemia revealed a significant effect on lymphocyte DLC. Furthermore, the frequent presence of mitotic and polychromatophilous erythrocytes in H. mauritanica-infected tortoises suggests a potential increase in erythrocyte regeneration.