SPINAL CORD脊髓
SPINAL CORD(英文缩写 SPINAL CORD),ISSN 1362-4393,eISSN 1476-5624,中文译名:脊髓 是一本学术期刊。本页汇总该期刊的最新影响因子、分区信息以及最新收录于 PubMed 的文献,帮助您快速了解期刊全貌。
发文量统计区间：2025-09-28 至 2026-09-28，按本站收录文献的发表日期统计。
期刊介绍
历年影响因子趋势
| JCR 数据年份 | 影响因子 | JCR 分区 |
|---|---|---|
| 2021 | 2.473 | Q2 |
| 2022 | 2.200 | Q2 |
| 2023 | 2.100 | Q1 |
| 2024 | 2.200 | Q1 |
| 2025 | 1.800 | Q2 |
SPINAL CORD 最新收录文献
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1. Efficacy of combined repetitive transcranial magnetic stimulation and occupational therapy in spinal cord injury patients: a randomized controlled clinical study.
PMID:日期:2026-09-22Randomized controlled trial, clinical trial. Impact evaluation of combined occupational therapy (OT) and transcranial magnetic stimulation (rTMS) on upper limb function in patients with spinal cord injury (SCI). National Rehabilitation Center, Seoul, Korea. This randomized controlled trial included patients with cervical SCI. One treatment group received OT and rTMS, while the other received OT and sham-rTMS, three times per week for 5 weeks. The primary study outcome (change in upper limb function) was assessed using the graded and redefined assessment of strength, sensibility, and prehension (GRASSP) and hydraulic hand dynamometer. Secondary outcomes included results from the Korean versions of the Spinal Cord Independence Measure III (KSCIM-III), visual analog scale (VAS), modified Ashworth scale (MAS), and Beck Depression Inventory-II. Intervention (IG) and control groups (CG) included 14 and 15 randomly assigned patients, respectively. The IG showed substantial improvements in strength, sensation, and perception when compared to CG. The KSCIM-III results showed greater improvements in IG than in CG. VAS, MAS, and BDI scores increased for pain, spasticity, and depression, respectively, in both groups. Shoulder pain increased significantly in the CG and BDI scores increased significantly in both groups. OT and rTMS combination therapy may contribute to upper extremity function improvements and more independence for patients with SCI.
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2. Blood flow restricted exercise with and without transcutaneous spinal cord stimulation via telehealth in persons with tetraplegia. A protocol for randomized clinical trial.
PMID:日期:2026-09-19A single site randomized clinical trial; Richmond, VA, USA. To determine the effect of 16 weeks of home-based blood flow restriction-enhanced neuromuscular electrical stimulation (BES) and non-invasive transcutaneous spinal cord stimulation (TSS) with mass practiced (MP) training on cervical neuroplasticity and upper extremity function in individuals with tetraplegia. The program is supported by a telehealth-based approach designed to improve adherence. Forty-four adults (18-70 years) with incomplete cervical SCI (AIS B-D; injury level C8 or above) will be randomized to TSS + BES + MP or sham TSS + BES + MP for 30 weeks. All participants, accompanied by a caregiver, will complete a 4-week education and training phase (2 weeks on-site, 2 weeks via telehealth), followed by 16 weeks of telehealth-supervised home training. Baseline assessments will occur before training (BL1) and after the education phase (Phase 1, BL2). Post-intervention (P1) testing will follow 16 weeks of home-based training (Phase 2), with an additional follow-up (Fw) after an 8-week washout period to evaluate any carry-over effects (Phase 3). The first 15 months will serve as a feasibility phase without randomization; data from these participants will be included within the TSS + BES + MP group. Randomization thereafter will be conducted using a computer-generated sequence. Home-based TSS application for upper extremity function is a feasible and safe strategy in persons with tetraplegia. The proposal is likely to ensure long-term compliance and adherence as well as to reduce the barriers associated with exercise interventions in persons with tetraplegia. National Institute on Disability, Independent Living, and Rehabilitation Research [NIDILRR]. CLINICALTRIALS NCT05423600.
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3. Predictive factors for postoperative motor recovery of proximal upper extremity in patients with degenerative cervical myelopathy: a multicenter prospective study.
PMID:日期:2026-09-18Multicenter prospective study. To clarify the postoperative course and predictive factors for motor recovery of the proximal upper extremity in patients with degenerative cervical myelopathy (DCM). Keio University School of Medicine and affiliated hospitals belonging to Keio Spine Research Group (KSRG). From a total of 1322 patients undergoing surgery for DCM, 363 patients with preoperative weakness in the deltoid or biceps brachii were included. Patients were divided into two groups based on their status at 2 years postoperatively: P group (persistent weakness; n = 131) and C group (complete recovery; n = 232). Variables including age, sex, medical history, duration of symptoms, surgical procedure, radiographic parameters, Japanese Otrhopaedic Association (JOA) scores, JOA Cervical Myelopathy Evaluation Questionnaire (JOACMEQ), SF-36, and pain scales were compared. P group was significantly older and had higher rates of hypertension, cerebrovascular disease, other musculoskeletal diseases, and prior cervical surgery. Preoperative JOA scores for upper extremity motor function were also significantly lower in P group (p < 0.05). Multivariate logistic regression analysis identified lower preoperative JOA motor scores (OR 3.27), prior cervical surgery (OR 3.29), history of other musculoskeletal diseases (OR 1.77), and history of hypertension (OR 1.64) as significant predictors of poor prognosis (p < 0.05). Surgical interventions are effective for motor recovery, with over 60% of patients achieving full strength. However, preoperative motor severity, prior surgery, history of other musculoskeletal diseases, and history of hypertension are key predictors of limited improvement. Level II.
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4. Statistical quality in RCTs of technology-based rehabilitation after spinal cord injury: A CHAMP-Based Meta-Research Study.
PMID:日期:2026-09-18Cross-sectional meta-research study. Technology-based rehabilitation (TBR) is increasingly used in spinal cord injury (SCI), with a growing number of randomised controlled trials (RCTs) evaluating its effectiveness. However, inadequate statistical reporting may limit the interpretation, reproducibility, and clinical applicability of findings. This study aimed to evaluate the statistical quality of RCTs investigating TBR interventions in individuals with SCI. MEDLINE, CINAHL Complete, Cochrane CENTRAL, PEDro, and Web of Science were searched from 1996 to October 2025. Eligible studies were superiority parallel-arm RCTs involving adults with traumatic or non-traumatic SCI evaluating TBR interventions and explicitly reporting adherence to the Consolidated Standards of Reporting Trials (CONSORT). Statistical quality was assessed using the Checklist for Statistical Assessment of Medical Papers (CHAMP), while methodological quality was evaluated using the Risk of Bias (RoB) 2 tool. Eight RCTs were included. Overall, CHAMP compliance was 57.9%, with over 40% of items rated as unclear or not fulfilled. Compliance was highest in the design domain (64.6%) and lower in the analysis (58.8%), interpretation (58.9%), and reporting (50.0%) domains. CHAMP scores ranged from 0.30-0.83. According to RoB 2, one study (12.5%) was judged at low risk of bias, five studies (62.5%) raised some concerns, and two studies (25.0%) were judged at high risk of bias. Statistical quality in RCTs of TBR in SCI is frequently suboptimal despite reported adherence to CONSORT guidelines. Greater transparency in statistical reporting is needed to improve the interpretation, reproducibility, and clinical applicability of rehabilitation research.
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5. Association between blood pressure instability and health-related quality of life in people with spinal cord injury.
PMID:日期:2026-09-16Observational cohort OBJECTIVE: The Blood Pressure Dysregulation (BPD) Measurement System (BPD-MS) was developed to assess the impact of BPD on health-related quality of life (HRQoL) and activities of daily living (ADL) in individuals with SCI. Association between BPD-MS scores and blood pressure (BP) measurements has not been reported. Academic Medical Center and Department of Veterans Affairs Medical Center METHODS: Sixty-five participants were enrolled, five had missing data and were not included in analyses. Data are reported in 60 participants with SCI at or above T6. Outcomes include 7-day home BP monitoring with end-of-day (EOD) BPD-MS t-scores on three BPD-MS surveys: (1) Low BP (LBP) HRQoL (LBP-HRQoL), (2) Autonomic Dysreflexia HRQoL (AD-HRQoL), and (3) impact of LBP on ADL (LBP-ADL). Higher scores on these surveys indicate more BPD-related health concerns. Between-person and within-person associations between BPD-MS scores and the average (Avg) and standard deviations (Std) for systolic BP (SBP) and diastolic BP (DBP) are reported. Weekly Avg SBP and DBP were not associated with scores on any of the BPD-MS surveys. Weekly Std SBP and Std DBP were significantly associated with between-subject LBP-HRQoL and LBP-ADL scores (all p ≤ 0.02). Associations between Std SBP and Std DBP with scores on the AD-HRQoL were not significant. Significant between-person effects suggest that individuals with more/less BP instability (Std) had greater/less negative impact on HRQoL and ADL. The findings indicate that the BPD-MS can be used to screen individuals who are more likely to be experiencing adverse health consequences of low BP instability.
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6. Cardiovascular effects of transcutaneous spinal stimulation in persons living with and without spinal cord injury.
PMID:日期:2026-09-15Case-control series. To investigate the cardiovascular effects of transcutaneous spinal stimulation (TSS) during orthostatic challenge in persons with and without spinal cord injury (SCI). Laboratory. Eleven persons with cervical SCI and ten persons without SCI participated in this study. Baseline systolic blood pressure (SBP) and heart rate (HR) were measured during an orthostatic challenge (10 min horizontal, 10 min upright). This was repeated with TSS (cathode: T7/T8 or T11/T12) applied when upright, and subsequently for 2 min when horizontal. SBP and HR were compared across groups and experimental conditions with linear mixed models. When upright without TSS, SBP increased in the non-SCI group but decreased in the SCI group (mean difference -19.8 mmHg [95% CI, -33.6 to -6.0]). When upright with TSS, SBP increased in the SCI group, similar to non-SCI group (T7/T8: -6.6 mmHg [-20.4 to 7.3], T11/T12: 2.5 mmHg [-11.3 to 16.3]; non-SCI - SCI). In participants with SCI and orthostatic hypotension (OH), TSS at T11/T12 limited the orthostatic drop by 25.8 mmHg [5.0 to 46.6]. When horizontal, TSS increased SBP in the SCI group (T7/T8: 24.7 mmHg [16.8 to 32.6], T11/T12: 27.2 mmHg [19.3 to 35.1]). Spinal stimulation at T11/T12 improved OH in persons with SCI. However, it also increases SBP when applied in a horizontal position, a caution for its clinical use. Future studies in people with SCI should explore the potential mechanisms responsible for these TSS-induced SBP effects.
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7. Operationalizing an early time-to-decompression best practice & monitoring approach in a provincial health system.
7. 在省级卫生系统中实施早期减压最佳实践和监测方法PMID:日期:2026-09-10A collaborative, multidisciplinary, provincial approach was constructed involving a provincial working group (WG) in a province-wide health system in Alberta, Canada to advance an early (< 24 h) time-to-decompression for adult patients with traumatic spinal cord injury (traumatic SCI). Key elements for the WG included the organizational context; theoretical foundation and guiding principles; pre-engagement activities; WG activities; and evidence reviews. This approach yielded inter-connected deliverables to advance early time-to-decompression in traumatic SCI: (1) a provincial best practice recommendation for Alberta's health system; (2) a near-real-time (weekly) provincial dashboard using a Large Language Model; and (3) a committed, local and provincial monitoring and learning approach. This work exposed early challenges to realizing and monitoring early spinal decompression for acute traumatic SCI in Alberta, and the opportunity to use artificial intelligence to capture near-real-time data for provincial improvement and learning at system-level. Balancing information in the dashboard led to noise in that data, which suits monitoring versus accountability framework. Merging community, learning and AI enabled multidisciplinary interest-holders in acute traumatic SCI to advance towards timely access to surgical decompression.Sponsorship: PRAXIS Spinal Cord Institute, Acute Care Alberta, Alberta Health Services.
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8. A new self-efficacy scale for people with a spinal cord injury; The General and Spinal Cord Injury Specific Self-efficacy Scale (G-SCI-SeS).
PMID:日期:2026-09-10A longitudinal cohort. This study aimed to be the first validation of the General and Spinal Cord Injury Specific Self-efficacy Scale (G-SCI-SeS), designed to capture both trait-like (general) and state-like (disease or SCI-specific) dimensions of self-efficacy (SE). Participants were followed from post-acute rehabilitation up to five years after discharge in the Netherlands. In the latest follow-up of a longitudinal spinal cord injury cohort, the G-SCI-SeS was administered alongside a general SE scale, two disease-specific SE scales, a distress scale and a life satisfaction scale. Among 142 participants with complete data, confirmatory factor analyses supported a two-factor structure, which demonstrated superior fit compared to a one-factor model. Internal consistency was excellent for the total score and General SE subscale, and good for the SCI-specific subscale. No floor effects and minimal ceiling effects were observed. Score distributions were non-normal, with a tendency toward higher values for all SE scales. Intercorrelations between the G-SCI-SeS and other SE scales were strong, even where moderate correlations were hypothesized. The G-SCI-SeS demonstrated a robust two-factor structure and moderate-to-good construct validity. Strong correlations between trait and state SE measures may reflect convergence of these constructs in the chronic phase of SCI. Developed through an iterative process incorporating cognitive interviews, the G-SCI-SeS appears suitable for clinical and research use. Further studies should investigate other forms of validity and the sensitivity of the G-SCI-SeS to change from the sub-acute phase to the chronic phase.
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9. Multidimensional immunometabolic changes and energy expenditure during intensive neurorestorative rehabilitation in chronic motor-complete thoracolumbar spinal cord injury: a quasi-experimental study.
PMID:日期:2026-09-09Single-group prospective quasi-experimental pre-post study. To evaluate metabolic, structural, immunological, and functional changes in individuals with motor-complete chronic thoracolumbar spinal cord injury (SCI) undergoing intensive neurorestorative rehabilitation. International Center for Neurological Restoration (CIREN), Havana, Cuba. Forty-one males (20-39 years) with AIS A/B thoracolumbar SCI completed a 12-week rehabilitation program (≈ 33.5 h/week). Dietary intake, estimated resting metabolic rate (RMR), estimated total and rehabilitation-related energy expenditure (time-motion methodology), anthropometry-based muscle mass, amino acid profile, lymphocyte subset percentages, and functional indices (Barthel and Katz) were assessed at baseline and post-intervention. Longitudinal changes were analyzed using covariate-adjusted linear mixed-effects models based on a Directed Acyclic Graph framework. Principal Component Analysis (PCA) was used to explore multidimensional adaptation. Estimated rehabilitation-related energy expenditure (β = 181.293, p < 0.001) and estimated RMR (β = 50.78, p = 0.042) increased, whereas dietary energy intake relative to estimated muscle mass decreased (β = -19.637, p = 0.001), despite a stable total energy intake. The anthropometric indicators of muscle mass, branched-chain amino acids, phenylalanine, and lymphocyte subset percentages increased significantly. Functional independence improved (Barthel β = 10.456, p < 0.001; Katz β = 9.305, p = 0.001). The PCA identified four interrelated dimensions that explained 47.1% of the variance. Intensive neurorestorative rehabilitation is associated with concurrent changes in multiple physiological domains in patients with chronic motor-complete SCI. Given the quasi-experimental design and reliance on estimated metabolic measures, the findings should be interpreted as hypothesis-generating.
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10. Relationships between dietary antioxidant capacity, systemic redox balance, and neuropathic pain after spinal cord injury.
PMID:日期:2026-09-09Cross-sectional study. To investigate the relationship between dietary antioxidant capacity, serum oxidant/antioxidant status, and neuropathic pain in individuals with chronic spinal cord injury (SCI). Tertiary Rehabilitation Hospital. Individuals aged 18-65 years with chronic traumatic SCI were included. Participants were classified by neuropathic pain status into SCI_NeuP (DN4 ≥ 4) and SCI_no-NeuP (DN4 < 4; pain-free at assessment, NRS = 0). Pain severity and pain interference were assessed using the Brief Pain Inventory. Dietary intake was evaluated via face-to-face interview using a semi-quantitative food frequency questionnaire, and dietary total antioxidant capacity (dTAC) was calculated using the Ferric Reducing Antioxidant Power database. To account for total energy intake, dTAC was expressed per 1000 kcal (dTAC/1000 kcal). Fasting serum total antioxidant status (TAS) and total oxidant status (TOS) were measured. The prespecified primary analysis was multivariable linear regression within SCI_NeuP with pain severity as the primary outcome; pain interference was a secondary outcome. Sixty-six participants were included (SCI_NeuP n = 33; SCI_no-NeuP n = 33). In SCI_NeuP, higher dTAC/1000 kcal was independently associated with lower pain severity (B = -1.655, 95% CI - 3.124 to -0.187; p = 0.029). dTAC/1000 kcal was not significantly associated with pain interference (B = -1.559, 95% CI - 3.412-0.294; p = 0.096). Serum TAS and serum TOS were not significantly associated with pain outcomes (all p > 0.05). Higher energy-adjusted dietary antioxidant capacity was associated with lower neuropathic pain severity after SCI, whereas no independent associations were observed for pain interference or serum TAS/TOS.