REVUE DES MALADIES RESPIRATOIRES呼吸系统疾病评论
REVUE DES MALADIES RESPIRATOIRES(英文缩写 REV MAL RESPIR),ISSN 0761-8425,eISSN 1776-2588,中文译名:呼吸系统疾病评论 是一本学术期刊。本页汇总该期刊的最新影响因子、分区信息以及最新收录于 PubMed 的文献,帮助您快速了解期刊全貌。
发文量统计区间：2025-09-27 至 2026-09-27，按本站收录文献的发表日期统计。
期刊介绍
历年影响因子趋势
| JCR 数据年份 | 影响因子 | JCR 分区 |
|---|---|---|
| 2021 | 0.714 | Q4 |
| 2022 | 0.600 | Q4 |
| 2023 | 0.500 | Q4 |
| 2024 | 0.500 | Q4 |
| 2025 | 0.500 | Q4 |
REVUE DES MALADIES RESPIRATOIRES 最新收录文献
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1. [Respiratory mucus: Exploring its viscoelastic properties and their relationship with mucociliary clearance abnormalities].
PMID:日期:2026-09-21Following an introduction on the structure and function of the respiratory mucus, we describe the viscoelastic properties of mucus, a key determinant of mucociliary clearance, along with the types of measurement devices most commonly used in laboratories. More specifically, this review presents macro- and micro-rheological methods for characterization of the respiratory mucus by means of small sample volumes. We discuss how study of the viscoelastic properties of mucus facilitates understanding of mucus abnormalities in respiratory muco-obstructive diseases and paves the way for the development of therapies effectively targeting mucin cross-linking molecules in view of enhancing patient management.
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2. [Paraganglioma diagnosed by EBUS-TBNA: A case report].
PMID:日期:2026-09-21Paragangliomas are rare neuroendocrine tumors occasionally found in the mediastinum. A characteristic CT presentation suffices to raise suspicions. Biopsy specimens are usually avoided, and diagnosis is generally based on a combination of biological, clinical and iconographic evidence. We report on the case of an 84-year old female patient without adrenergic signs, who presented with an isolated mid-mediastinal lesion, which was found on FDG-TEP to be hypermetabolic. Its appearance was suggestive of a neuroendocrine tumor or a clear cell renal tumor, leading to investigation by EBUS-TBNA. The cytology aspirations subsequently performed were complicated by moderate bleeding, which was controlled by local instillations of adrenalized serum. An anatomopathological diagnosis of paraganglioma ensued, and was confirmed by further endocrinologic investigations. Notwithstanding its technical feasibility, assessment of mediastinal paragangliomas by EBUS-TBNA may present an increased risk of moderate to severe bleeding. Appropriate safety measures should be considered, as well as diagnosis by non-invasive methods alone.
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3. [The role of thrombomodulin in pulmonary hypertension associated with bronchopulmonary dysplasia in preterm infants].
PMID:日期:2026-09-21Bronchopulmonary dysplasia (BPD) is the most common chronic respiratory disease in premature newborns born before 32 weeks of gestation. It is characterized by arrested lung growth (hypoalveolarization), rarefaction of microvascularisation (hypoangiogenesis), and inflammation. BPD can be complicated by pulmonary hypertension (PH-BPD), which increases the mortality rate by nearly 50% within two years after diagnosis. Thrombomodulin is a glycoprotein mainly expressed on vascular endothelial cells. It plays a central role in hemostasis, but also contributes to inflammation and angiogenesis and is used as a biomarker in certain cardiopulmonary pathologies. Deregulation of its expression may therefore play an important role in the development of inflammatory diseases and/or angiogenesis defects, such as PH-BPD.
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4. [Role of energy metabolism in pediatric asthma].
PMID:日期:2026-09-21Asthma, which is the most common chronic respiratory disease in children, results from complex interactions between genetic factors, immune responses and environmental stimuli. Increasing evidence highlights energy metabolism and mitochondrial function as major contributors to the pathophysiology of pediatric asthma. Several mitochondrial genes have been identified as potential biomarkers associated with the disease, and at the cellular level, mitochondrial dysfunction has been linked to bronchial smooth muscle remodeling, one of the key aspects of disease severity. Taken together, these insights underscore the importance of characterizing energy metabolism and mitochondrial function in view of identifying new therapeutic targets for pediatric asthma.
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5. [Bronchiectasis in children: An underdiagnosed disease with accessible screening and etiological assessment].
PMID:日期:2026-09-21Long considered as a rare and neglected disease, non-cystic fibrosis bronchiectasis in children is now recognized as an emerging cause of chronic respiratory morbidity worldwide. Its incidence is strikingly variable, ranging from 0.2-2.3 per 100,000 children annually in high-income countries to more than 700 per 100,000 in some groups of children living in highly deprived socio-economic settings. Recent data from the Child-BEAR-Net international registry confirm the predominance of post-infectious forms (∼30%) and immunodeficiencies (∼20%), while also highlighting the role of primary ciliary dyskinesia (∼10-15%) and rarer etiologies such as congenital malformations or allergic bronchopulmonary aspergillosis. In low-resource settings, pediatric bronchiectasis remains underdiagnosed and frequently misinterpreted as asthma or tuberculosis, leading to delayed management and worsened bronchial damage. However, unlike in adults, the pediatric bronchial tree retains capacity for remodeling, and if promptly treated, early lesions may regress. Recognizing chronic productive cough as a cardinal symptom, combined with early screening and a multidisciplinary approach (respiratory physiotherapy, targeted antibiotic therapy, immunoglobulin replacement, and nutritional support), can significantly improve outcomes. Future priorities include dissemination of international guidelines (ERS 2021), establishment of national registries, and development of screening programs tailored to low-resource contexts. Some forms of pediatric bronchiectasis, particularly post-infectious forms, may be preventable, and early lesions in selected children may improve following timely diagnosis and management.
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7. [Toward novel therapeutic strategies: Targeting the extracellular matrix to broaden the therapeutic window].
PMID:日期:2026-08-11Lung cancer is a major public health concern, ranking as the third most common cancer in women and the second in men, entailing significant mortality. Immune checkpoint inhibitors (ICIs, anti-PD-1/PD-L1) have transformed the treatment of advanced lung adenocarcinoma, thereby prolonging survival. However, many patients develop therapeutic resistance. Increased stiffness of the extracellular matrix (ECM) of the tumor represents a critical obstacle to immunotherapy efficacy, limiting lymphocyte infiltration. Modulation through integrins of the mechanical properties of the ECM could restore immune accessibility and potentiate ICIs, opening new therapeutic perspectives for treatment of advanced lung cancer.
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8. [Pathophysiology of pulmonary fibrosis associated with monogenic defects of telomere homeostasis].
PMID:日期:2026-08-10Fibrosing interstitial lung diseases, including idiopathic pulmonary fibrosis (IPF), are frequently associated with abnormalities in telomere homeostasis. Heterozygous pathogenic variants in telomere-related genes (TRGs) are found in 20-35% of patients with familial pulmonary fibrosis. These genetic defects are associated with impaired telomere homeostasis, which can lead to cellular senescence. Type II pneumocytes, the progenitor cells of the alveolar epithelium, are particularly sensitive to these genetic defects. Their senescence disrupts alveolar regeneration and promotes fibrosis by the production of profibrotic mediators. Autosomal dominant PARN deficiency provides a model for understanding the molecular mechanisms underlying pulmonary fibrosis associated with monogenic defects in telomere homeostasis, and developing targeted therapies.
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9. [Pleural sarcoidosis: A diagnostic challenge in countries with high tuberculosis prevalence].
PMID:日期:2026-08-10A 70-year-old female patient presented with exudative, lymphocytic left-sided pleural effusion. Blind pleural biopsy histology revealed granuloma without caseous necrosis. Oral corticosteroid therapy was well tolerated and proved effective following one month of treatment.
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10. [The role and utilization of transcutaneous capnography in respiratory failure patients. Chronicles: A review of the literature and an expert opinion].
PMID:日期:2026-08-07Transcutaneous capnography (PCO) provides a non-invasive estimate of partial arterial pressure of carbon dioxide in the blood and is an increasingly widely used tool for assessing alveolar hypoventilation, particularly nocturnal hypoventilation, in patients with chronic respiratory failure. That much said, its reliability in clinical practice requires satisfactory understanding of the relevant technical principles, conditions of implementation, and analysis methods. This work is based on expert opinions from the Ventilatory Assistance and Oxygen Therapy Group (GAVO) of the French-speaking Pulmonology Society (SPLF). The data available in the literature were analyzed and discussed in view of providing practical advice on the performance, analysis, and interpretation of nocturnal PCO recordings in adults. Under optimal technical conditions, PCO correlates well with PaCO, with bias generally lower than 0.5kPa. The quality of recording is a determining factor and depends on proper sensor placement, continuous recording for a sufficient amount of time, and prior analysis of the curves aimed at identifying artifacts and measurement drifts. Definitions of nocturnal hypoventilation based on PCO remain heterogeneous and are based primarily on expert opinion. Transcutaneous capnography is a relevant non-invasive tool ensuring assessment of alveolar hypoventilation in adults with chronic respiratory failure, provided that the technical and interpretative aspects are fully mastered and rigorously applied. It should complement blood gases as part and parcel of a comprehensive clinical approach.