VETERINARY QUARTERLY兽医季刊
VETERINARY QUARTERLY(英文缩写 VET QUART),ISSN 0165-2176,eISSN 1875-5941,中文译名:兽医季刊 是一本学术期刊。本页汇总该期刊的最新影响因子、分区信息以及最新收录于 PubMed 的文献,帮助您快速了解期刊全貌。
发文量统计区间：2025-11-01 至 2026-10-31，按本站收录文献的发表日期统计。
期刊介绍
历年影响因子趋势
| JCR 数据年份 | 影响因子 | JCR 分区 |
|---|---|---|
| 2021 | 8.071 | Q1 |
| 2022 | 6.400 | Q1 |
| 2023 | 7.900 | Q1 |
| 2024 | 5.200 | Q1 |
| 2025 | 3.900 | Q1 |
VETERINARY QUARTERLY 最新收录文献
-
1. Artificial intelligence and laboratory biomarkers in veterinary medicine: an update about machine learning applications.
1. 兽医学中的人工智能和实验室生物标志物：机器学习应用的最新进展PMID:日期:2026-09-17The use of artificial intelligence has been a revolution in human medicine in the last years. Machine learning (ML), a subset of artificial intelligence, has allowed the use of a large amount of data to search for associations of clinical significance. Although the use of ML with laboratory biomarkers in veterinary medicine is limited in comparison with the human side, the number of studies published in this field is increasing in recent years. This review addresses some basic concepts and gives a general overview of the use of ML in the area of biomarkers in veterinary medicine. It is especially focused on two species of each companion (dogs and cats) and farm (bovine and porcine) animals, and provides information about the advances made in the last years, indicating how ML using laboratory data can contribute to the diagnosis and monitoring of selected diseases and, in case of farm animals, also to better control and improve their productive performance. In addition, possible new applications such as optimizing laboratory management, refining diagnostics or improving treatment monitoring based on the experience in humans are outlined. This narrative review can contribute to a better knowledge about the possible use of ML in laboratory biomarkers in veterinary and animal sciences for current and future applications.
-
2. Evaluation of a 0.05 T low-field MRI system for canine brain imaging via comparison with images acquired at 1.5 T field strength: a pilot cadaver study.
PMID:日期:2026-09-12Magnetic resonance imaging (MRI) systems continue to grow in number in veterinary and human medicine with higher field strength magnets increasingly available; however, the associated high costs have created healthcare inequities. This technical feasibility study aimed to evaluate a low-cost, portable, and permanent magnet-based 0.05 T low-field system (LF), originally designed for human neuroimaging, for assessing the canine brain. By using 23 canine cadavers, a scanning protocol was developed, consisting of transverse T1-weighted (T1w) and T2-weighted (T2w) sequences, and compared to a 1.5 T (HF) protocol for the visibility of 22 anatomical features. For the purpose of hydrocephalus evaluation, the LF system showed non-inferior detection of the lateral ventricles (LV) and mesencephalic aqueduct on T2w sequences with >90% conditional probability for detecting these features on the LF, given they were present on the HF. For T1w sequences, the LF system had inconclusive non-inferiority for detection of LV with 76.6% conditional probability. In summary, a canine brain scanning protocol was successfully developed for a 0.05 T MRI with preliminary evaluation suggestive that this device can aid with the detection of hydrocephalus. Future studies are required to evaluate the device's true clinical application.
-
3. Structural characterization of PAMK and its protective effect against thymic necroptosis in goslings.
PMID:日期:2026-09-01PAMK are heterogeneous glycans with immunomodulatory potential, but their structural basis and mechanisms in regulating thymic injury remain unclear. Structural characterization revealed that PAMK is mainly composed of arabinose, galactose, rhamnose, galacturonic acid, and glucose, featuring a dominant backbone consisting of →4)--D-GalpA-(1→, →4)--D-Galp-(1→, →2)--L-Rhap-(1→, and →3,4)--D-GalpA-(1→ with highly branched side chains. This complex structure provides the biochemical foundation for its bioactivity. To explore its immunoprotective effects, we established a CTX-induced thymic necroptosis model in goslings. CTX markedly disrupted cytokine profiles and activated necroptosis signaling, accompanied by downregulation of novel-miR-2 and upregulation of TRADD and MLKL. Dietary PAMK supplementation significantly restored cytokine homeostasis and inhibited necroptosis pathway activation. Mechanistically, PAMK upregulated novel-miR-2, which negatively regulated TRADD and MLKL expression, thereby attenuating necroptosis signaling. Overexpression of novel-miR-2 suppressed TRADD/MLKL-mediated necroptosis, whereas its inhibition produced the opposite effect. Furthermore, PAMK mitigated oxidative stress and necroptotic cell death induced by TRADD and MLKL overexpression. Collectively, our findings demonstrate that the defined structural features of PAMK underpin its ability to protect against CTX-induced thymic necroptosis by upregulating novel-miR-2 and suppressing the TRADD/MLKL axis. This work links PAMK's composition to its immunoprotective function and highlights its potential as a safe immunoregulatory agent in poultry.
-
5. LNC_003296 regulates the proliferation and differentiation of ovine myoblasts by modulating the stability of Hsp70.
PMID:日期:2026-08-25Long non-coding RNAs (lncRNAs) are involved in various regulatory processes during muscle development. Our previous RNA-seq study identified LNC_003296 as being significantly differentially expressed between ovariectomized Small-tailed Han sheep (OR-STH) and their non-ovariectomized counterparts (STH). Through biotinylated RNA pull-down assays and RNA immunoprecipitation (RIP), we further demonstrated that LNC_003296 directly interacts with Hsp70. Protein stability and degradation experiments revealed that LNC_003296 enhances the protein stability of Hsp70. Overexpression of either LNC_003296 or Hsp70 promoted myoblast proliferation, facilitated differentiation, and contributed to skeletal muscle fiber formation. Conversely, their knockdown suppressed cell proliferation and inhibited differentiation. In summary, these data indicate that LNC_003296 can bind to Hsp70 and enhance its protein stability, thereby influencing the proliferation and differentiation of myoblasts.
-
6. Rethinking dog stress behaviours: contextual and physiological insights from the attachment framework.
PMID:日期:2026-08-21While dogs' behavioural indicators of psychological stress are widely used, their function as reliable stress markers remains debated. Using the Strange Situation Procedure (SSP) as a social-stress paradigm, we evaluated contextual correlates of dog behaviours to explore their validity as stress indicators. In 64 dogs, behaviours commonly used as stress markers were video-coded and analysed via GLMMs to investigate differences across test episodes and attachment styles (secure, anxious, avoidant), while salivary cortisol, oxytocin, and rectal temperature provided a physiological framework. Episode had significant effects on shaking ( < 0.05), lip-licking ( < 0.001), paw-lifting ( < 0.001), whining ( < 0.001), head-turning ( < 0.001), sniffing the door ( < 0.001), and locomotion ( < 0.001), while attachment style significantly affected head-turning only ( = 0.004). Our findings suggest that the observed behaviours were not expressed linearly in relation to expected stress levels across the SSP episodes. This lack of linearity, combined with the divergent physiological correlates found across attachment groups-for instance, oxytocin correlated positively with lip-licking in securely attached dogs ( < 0.05), but negatively in anxious ones ( < 0.05) -, suggests that these behaviours do not function as simple stress indicators. Rather, their meaning appears to be contingent upon the individual's internal state and the socio-environmental context. We discuss our results in light of an alternative semiotic interpretative framework.
-
7. Photodynamic antimicrobial and antineoplastic therapy in veterinary medicine: current status, challenges, and perspectives.
PMID:日期:2026-08-16Significant causes of morbidity in veterinary medicine are tumourigenic diseases and pathogenic infections, which pose significant threats to animal health. Traditional methods for treating tumours and bacterial infections primarily involve chemotherapy and antibiotic therapy, both of which are associated with drug resistance and adverse effects. Photodynamic therapy (PDT) is gaining increasing interest in veterinary clinical practice because of its distinctive benefits such as spatiotemporal selectivity, low toxicity, fewer negative effects, and reduced risk of drug resistance. This review summarises the fundamental principles of PDT and its applications in combating tumours and microbial infections in veterinary practice involving companion animals, livestock, wildlife, and reptiles. It is worth noting that the existing clinical evidence is limited by very small sample sizes and the absence of comparator groups; however, these studies have provided a preliminary theoretical foundation and technical reference for further clinical development of PDT. Moreover, the opportunities and challenges associated with PDT in veterinary clinical practice are discussed herein.
-
8. AI-assisted post-mortem classification of vehicle trauma in free-roaming cats using transformer-based large language models.
8. 使用基于transformer的大型语言模型对自由漫游猫的车辆创伤进行人工智能辅助尸检分类PMID:日期:2026-08-03Veterinary forensic science is a specialized discipline that investigates non-natural animal deaths and injuries. Determining the cause of death in free-roaming cats often presents challenges due to underdeveloped pattern recognition methods and the intricate interplay of events and contributing factors. The integration of natural language processing into forensic investigations may offer potential for the computerized automation of document analysis, with the goal of supporting investigational decision-making. The objective of this study was to develop an AI framework leveraging a transformer-based large language model (LLM) to classify veterinary forensic autopsy reports derived from 271 feline autopsies and to identify the causes of death. We first identified discriminative lexical patterns between vehicular trauma (VT; = 111) and non-VT cases ( = 160) using Term Frequency-Inverse Document Frequency analysis. The best-performing model, based on Clinical-Longformer, achieved an accuracy of 0.945, precision of 0.885, recall of 1.000, F1 score of 0.939, and AUC-ROC of 0.950. Model interpretability using Integrated Gradients revealed that VT cases were characterized by terms associated with traumatic physical injuries, whereas non-VT cases exhibited a broader range of diagnostic descriptions. These findings demonstrate the feasibility of applying LLMs to veterinary forensic pathological texts and underscore the importance of domain-specific token interpretation for model explainability.
-
9. Apoptosis inhibitor of macrophage (AIM/CD5L) as a potential immunomodulator in feline injection-site sarcoma: a hypothesis on tumor-macrophage interactions.
PMID:日期:2026-08-02AIM (apoptosis inhibitor of macrophage), also known as CD5L, is a macrophage-derived scavenger protein with broad immunomodulatory roles in mammals. Secreted by tissue macrophages, AIM circulates bound to IgM pentamers, which stabilize the protein in blood; free AIM is released during inflammation to influence immune signaling and cellular homeostasis. (Yang et al. 2023). In cats, AIM exhibits distinctive structural and biochemical properties, existing as both a three-domain (37 kDa) and a four-domain (45 kDa) variant generated through exon 3 duplication (Evangelista et al. 2025), and binding IgM approximately 1000-fold more tightly than murine AIM due to a species-specific positively charged cluster in its third SRCR domain (Miyazaki et al., 2018). These differences suggest feline AIM may function distinctly from human/mouse AIM. Feline injection-site sarcomas (FISS) arise in the context of chronic inflammation and frequently contain abundant tumor-associated macrophages (TAMs)associated with tumor aggressiveness and progression (Gomes et al., 2025). Given AIM's macrophage origin and its established roles in inflammatory regulation, autophagy signaling, and complement-mediated tumor targeting, we propose a directional hypothesis: that the high-affinity IgM-binding of feline AIM constrains free AIM availability in vivo, shifting the functional balance away from complement-mediated tumor cytotoxicity and toward macrophage-intrinsic M2-polarizing pathways, thereby promoting an immunosuppressive tumor microenvironment that contributes to FISS progression. Exploring AIM in this context may provide new perspectives for investigation in feline tumor immunology.
-
10. Comparative validation of LC-MS, micro-bioassay, and ELISA for lincomycin quantification: application to pharmacokinetic analysis in healthy and co-infected porcine models.
10. LC-MS、微量生物测定和ELISA用于林可霉素定量的比较验证：应用于健康和共感染猪模型的药代动力学分析PMID:日期:2026-07-25This study compared liquid chromatography-mass spectrometry (LC-MS), micro-bioassay (MBa), and enzyme-linked immunosorbent assay (ELISA) for quantification of lincomycin (10 mg/kg BW) in porcine serum and evaluated lincomycin pharmacokinetic (PK) data in healthy piglets also co-infected with and . All methods satisfied standard bioanalytical validation criteria, including low limits of detection and quantification, acceptable intra-assay imprecision and error, and strong linearity across clinically relevant concentration ranges. Serum concentrations measured by MBa and ELISA showed high correlation with LC-MS in both healthy and infected models (Pearson r ≥ 0.97, low bias on Bland-Altman analysis); they produced comparable PK parameters (Cmax, Tmax, area under the curve [AUC], clearance, and mean residence time), indicating suitability for PK/pharmacodynamic (PD)-based dose optimization. PK analysis demonstrated rapid absorption after intramuscular administration and disease-associated alterations in selected distribution and disposition parameters. AUC and clearance were nearly similar across analytical methods and largely consistent between software platforms (WinNonlin and PKSolver). Thus, lower-cost MBa and ELISA-combined with freely available PKSolver-can generate robust, decision-relevant PK/PD data for lincomycin in swine, providing a practical framework for antimicrobial dose refinement and stewardship in resource-limited veterinary and farm settings.