JOURNAL OF MEDICAL PRIMATOLOGY医学灵长类学杂志
JOURNAL OF MEDICAL PRIMATOLOGY(英文缩写 J MED PRIMATOL),ISSN 0047-2565,eISSN 1600-0684,中文译名:医学灵长类学杂志 是一本学术期刊。本页汇总该期刊的最新影响因子、分区信息以及最新收录于 PubMed 的文献,帮助您快速了解期刊全貌。
发文量统计区间：2025-09-27 至 2026-09-27，按本站收录文献的发表日期统计。
期刊介绍
历年影响因子趋势
| JCR 数据年份 | 影响因子 | JCR 分区 |
|---|---|---|
| 2021 | 0.821 | Q4 |
| 2022 | 0.700 | Q3 |
| 2023 | 0.800 | Q3 |
| 2024 | 0.500 | Q4 |
| 2025 | 0.500 | Q4 |
JOURNAL OF MEDICAL PRIMATOLOGY 最新收录文献
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1. Evaluation of Sedative and Physiological Effects of Intramuscular or Intranasal Ketamine-Midazolam and Ketamine-Dexmedetomidine in Capuchin Monkeys (Sapajus sp.).
PMID:日期:2026-10-01This study evaluated the sedative and physiological effects of intramuscular (IM) or intranasal (IN) ketamine-midazolam and ketamine-dexmedetomidine in capuchin monkeys (Sapajus sp.). Twenty-four capuchin monkeys were randomly assigned into four groups (6 per group) to be administered ketamine (15 mg/kg) combined with midazolam (0.5 mg/kg) or dexmedetomidine (5 μg/kg) IM (KM and KD groups, respectively) or IN (KM and KD groups, respectively). Physiological variables, sedation scores, and anesthetic recovery times were evaluated. All protocols resulted in tachypnea and heart rate values within the range indicated for the species. Blood pressure was significantly higher in KD compared with KM. All animals in KM and KD, and three animals in KM and KD, adopted lateral recumbency. Sedation, muscle relaxation, resistance to dorsal recumbency, and mandible tone scores were higher in KM and KD compared to KD. Posture scores were higher in KM and KD compared to KM. Time to standing was longer in KM and KD than in KD. All protocols promoted tachypnea and few effects on HR and blood pressure. KM and KD result in deep sedation. KM and KD result in light sedation. Anesthetic recovery was faster with KD.
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3. Analysis of the Osmolarity of the Liquid Fraction of Squirrel Monkey's Semen (Saimiri collinsi Osgood, 1916) in Fattening and Non-Fattening Conditions.
3. 肥胖与非肥胖条件下松鼠猴（Saimiri collinsi Osgood，1916）精液液体部分渗透压分析PMID:日期:2026-10-01The aim was to determine seminal osmolarity in S. collinsi and evaluate whether it, along with seminal parameters, varies between fattening and non-fattening conditions and across age groups. Biometric and seminal parameters were evaluated in nine S. collinsi males across conditions. Mixed-effects models assessed reproductive parameters and seminal quality. Seminal osmolarity ranged from 300 to 500 mOsm/L and varied with age and fattening condition. Testicular volume was lower during non-fattening. Seminal osmolarity showed linear and quadratic associations with reproductive biometry and sperm quality. Seminal volume decreased with increasing osmolarity, whereas sperm morphology and vigor showed non-linear associations. Age was negatively associated with plasma membrane integrity and sperm morphology, while sperm concentration and motility were not significantly affected. Seminal osmolarity and age are associated with reproductive and sperm functional parameters, establishing the first baseline for seminal osmolarity in this species and supporting reproductive biotechnology and conservation strategies.
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4. Spontaneous Hepatobiliary Disease in a Breeding Colony of Aotus spp.
PMID:日期:2026-10-01Owl monkeys are nonhuman primate species in the genus Aotus. The Michale E. Keeling Center for Comparative Medicine and Research maintains an Owl Monkey Breeding and Research Resource composed of four species of owl monkeys: Aotus nancymai, A. vociferans, A. azarae, and A. griseimembra. Disease of the hepatobiliary system has not been well characterized in Aotus. Necropsy records from a 17-year period were reviewed to characterize the gross and microscopic lesions of liver disease. 316 adult owl monkeys were submitted for necropsy in the review period; 22 of 316 (6.96%) were diagnosed with hepatobiliary disease. Cardiac-associated hepatopathy was the most common diagnosis (6/22). Previously unreported conditions included cystic mucinous hyperplasia (1/22), acute cholangiohepatitis (1/22), idiopathic end-stage hepatopathy (1/22), cholangiocarcinoma (2/22), and acute cholecystitis (4/22). Vitamin E deficiency anemia (3/22) and hemosiderosis (4/22) have been reported in the genus, and these diagnoses were noted. The spectrum of hepatobiliary pathology in owl monkeys is broader than previous reports have suggested.
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5. Comparative Immunopathology of Toxoplasma gondii Natural Infections in Marmosets (Callithrix spp.) and Howler Monkeys (Alouatta spp.), Brazil.
PMID:日期:2026-10-01Neotropical primates (NTPs) present varying susceptibility to toxoplasmosis caused by Toxoplasma gondii, but their immunopathogenic responses remain poorly understood. Local immune responses were characterized in the liver, spleen, and central nervous system (CNS) of 50 naturally infected NTPs (31 Callithrix spp.; 19 Alouatta spp.) by immunohistochemistry. Splenic white pulp morphometry, CD3+ T lymphocyte, Iba1+ macrophage/microglia, polymorphonuclear neutrophil quantification, and IFN-γ and IL-10 semi-quantification were performed. Both genera exhibited splenic white pulp hyperplasia. Within genera, marmosets showed predominant CD3+ infiltrates in the spleen and histiocytic infiltrates in the liver and CNS, whereas howler monkeys exhibited predominantly histiocytic infiltrates in all tissues. Between genera, marmosets had significantly higher splenic CD3+ T-cell (p < 0.05), Iba1+ macrophage (p = 0.030), and IFN-γ (p = 0.018) immunolabeling than howler monkeys.
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6. The First Evidence of Intermittent Rectal Prolapse in a Wild Chimpanzee (Pan troglodytes).
PMID:日期:2026-10-01Rectal prolapse in wild chimpanzees has been rarely reported. We document a case of rectal prolapse in a wild young male chimpanzee at Mahale Mountains National Park, Tanzania. An affected young male in the Mahale M group was observed with photographs/video and diagnosed according to operational criteria used in human (Oxford grading system). Cause and course of the prolapse were estimated by a set of longitudinal field data. An intermittently self-reducing full-thickness rectal prolapse was diagnosed. Protrusion fluctuated within minutes; tenesmus and diarrhea were absent; and the mucosa remained bright red and viable, without necrosis or myiasis. Post-traumatic pelvic-floor/anal-sphincter nerve dysfunction after conspecific bite injury on the buttock was estimated as the cause. This is the first report of rectal prolapse in wild chimpanzees. The detailed natural course of this persistent condition without medical intervention provides information relevant to case-specific management decisions in wild apes.
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7. Opportunistic Screening for Bone Demineralization by Whole Body CT in a Red-Handed Howler Monkey (Alouatta belzebul) Under Human Care.
PMID:日期:2026-10-01An eight-year-old male red-handed howler monkey (Alouatta belzebul) underwent whole-body computed tomography for gastrointestinal signs. Quantitative CT of the lumbar vertebrae opportunistically revealed severe bone hypoattenuation, demineralization, and deteriorated trabecular architecture. This incidental diagnosis of metabolic bone disease was directly attributed to chronic inadequate management conditions, specifically a severely imbalanced diet and insufficient sunlight exposure in captivity.
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8. Non-Human Primates as Sentinels and Reservoirs of Emerging Zoonotic Diseases in Indonesia: A One Health Perspective on Pathogen Spillover, Surveillance Gaps, and Regulatory Frameworks.
PMID:日期:2026-10-01Indonesia harbors extraordinary non-human primate (NHP) diversity, yet deforestation, ecotourism, illegal wildlife trade, and urban encroachment are intensifying human-NHP contact, elevating pathogen spillover risk. This review synthesizes evidence on NHP-associated zoonoses within a One Health framework and proposes an integrated biosurveillance roadmap. A structured search of PubMed, Scopus, and Web of Science (2000-2025), informed by the PRISMA-ScR framework and using pre-specified host, geographic, and pathogen search terms, was conducted and supplemented by grey literature from WHO, FAO, BPOM, and Indonesia's Ministry of Health. Five priority zoonotic pathogen categories were identified: Plasmodium knowlesi malaria, Macacine alphaherpesvirus 1 (Herpes B virus), simian foamy virus, Mycobacterium tuberculosis complex, and zoonotic gastrointestinal parasites. Surveillance capacity is fragmented and NHP-specific pathogen monitoring is absent from national systems. NHP-derived zoonoses represent a growing public health threat in Indonesia. A NHP-inclusive One Health surveillance system integrating molecular diagnostics, geographic information systems, and cross-sectoral regulatory coordination is urgently needed.
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9. Frequency of Klebsiella spp. and Antimicrobial Resistance Patterns in Clinically Healthy Captive Night Monkeys (Aotus nancymaae) in the Peruvian Amazon.
PMID:日期:2026-10-01Klebsiella spp. are opportunistic enterobacteria associated with a wide range of infections in humans and animals and are increasingly recognized as important pathogens due to their ability to acquire antimicrobial resistance. Captive wildlife populations, including non-human primates, may serve as carriers of these bacteria and are susceptible to bacterial outbreaks under certain management and environmental conditions. This study aimed to describe the antimicrobial susceptibility profile of Klebsiella spp. isolated from clinically healthy captive night monkeys (Aotus nancymaae) housed at the IVITA-Iquitos breeding center in the Peruvian Amazon. A total of 86 clinically healthy night monkeys were sampled. Rectal swabs were collected for bacterial isolation and identification. Antimicrobial susceptibility testing was performed using the Kirby-Bauer disk diffusion method according to Clinical and Laboratory Standards Institute (CLSI) guidelines. Associations between bacterial isolation and demographic variables were evaluated. Klebsiella spp. were isolated from 10.5% (9/86) of the animals. The frequency of isolation was highest among juveniles, followed by infants and adults, with a significant association between age group and bacterial isolation (p < 0.05). No association was observed with sex. Most isolates (79.2%) were susceptible to all tested antimicrobials, four isolates (16.7%) exhibited intermediate susceptibility to at least one antimicrobial, and only one isolate (4.2%) showed resistance, specifically to ciprofloxacin. No multidrug-resistant isolates were identified. The results indicate a low frequency of antimicrobial resistance among Klebsiella spp. isolates recovered from clinically healthy captive night monkeys. These findings provide baseline information on the occurrence of Klebsiella spp. and antimicrobial susceptibility in this population. Continued microbiological surveillance is recommended to support preventive health management and facilitate the early detection of changes in antimicrobial susceptibility patterns in captive neotropical primates.
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10. Nonpathogenic SIV Infection in Sooty Mangabeys Is Characterized by a Lack of Activation and Expansion of Monocytes.
PMID:日期:2026-10-01Natural hosts of simian immunodeficiency virus (SIV), including sooty mangabeys (SMs), maintain high viremia without progressing to AIDS and AIDS-associated histopathogenesis. The mechanisms underlying this protection and lack of pathogenesis remain incompletely understood, particularly in relation to monocyte/macrophage activation. Plasma soluble CD163 (sCD163), monocyte CD163 expression, and monocyte subset phenotypes were quantified in uninfected and naturally SIV-infected SMs and compared with uninfected and SIV-infected rhesus macaques (RMs). Flow cytometry and multivariate analyses were used to assess monocyte activation and subset distribution. sCD163 levels and CD163 surface expression were increased in SIV-infected RMs but not SMs. SIV-infected SMs exhibited reduced CD14CD16 monocyte expansion and lower expression of CD64, MAC387, CD11b, and CCR2 compared with SIV-infected RMs. Machine learning identified CD14CD16CCR8 monocytes as the top discriminator of SIV infection in SMs. These findings indicate a lack of monocyte activation in SMs that correlates with non-pathogenic infection.