JOURNAL OF GENERAL PHYSIOLOGY普通生理学杂志
JOURNAL OF GENERAL PHYSIOLOGY(英文缩写 J GEN PHYSIOL),ISSN 0022-1295,eISSN 1540-7748,中文译名:普通生理学杂志 是一本学术期刊。本页汇总该期刊的最新影响因子、分区信息以及最新收录于 PubMed 的文献,帮助您快速了解期刊全貌。
发文量统计区间：2025-09-24 至 2026-09-24，按本站收录文献的发表日期统计。
期刊介绍
历年影响因子趋势
| JCR 数据年份 | 影响因子 | JCR 分区 |
|---|---|---|
| 2021 | 4.000 | Q2 |
| 2022 | 3.800 | Q2 |
| 2023 | 3.300 | Q1 |
| 2024 | 2.900 | Q2 |
| 2025 | 3.200 | Q2 |
JOURNAL OF GENERAL PHYSIOLOGY 最新收录文献
-
1. State-dependent inhibition of LRRC8 volume-regulated anion channels by DCPIB.
PMID:日期:2026-11-02DCPIB is the prototypical inhibitor of leucine-rich repeat containing protein 8 volume-regulated anion channels (VRACs), yet the structural basis and state dependence of inhibition remain unclear. Her…
-
2. A fluorescent non-hydrolyzable probe for the nucleotide-binding sites of KATP.
PMID:日期:2026-11-02Neuroendocrine ATP-sensitive K+ channels (KATP) comprise four pore-forming subunits (Kir6.2), each associated with a modulatory sulfonylurea receptor subunit (SUR1). ATP/ADP binding to Kir6.2 inhibits…
-
3. The proximal N terminus of IRAG is required for potentiation of HCN4 channels.
PMID:日期:2026-11-02The inositol triphosphate-associated, ER transmembrane proteins inositol triphosphate receptor-associated guanylate kinase substrate (IRAG) and lymphoid restricted membrane protein (LRMP) are isoform-…
-
4. Correction: Evolution, hibernation, and inactivation of voltage-gated Na channels.
PMID:日期:2026-11-02该文献暂无摘要。
-
5. The many faces of Orai1 dysfunction: Molecular mechanisms and clinical manifestations.
PMID:日期:2026-11-02Orai1, the pore-forming subunit of the calcium (Ca2+) release-activated Ca2+ (CRAC) channel, plays a central role in store-operated Ca2+ entry (SOCE) in animal cells and thereby serves as a key regula…
-
6. Tunable AMPA receptor function via recurrent evolution of heterotetramers.
PMID:日期:2026-11-02Most ionotropic neurotransmitter receptors are hetero-oligomers of three to five homologous subunits assembled into membrane-spanning ion channels. Mammalian AMPA-type glutamate receptors (AMPARs), wh…
-
7. A hERG blocker facilitates K+ channel current by promoting pore opening while blocking.
7. hERG阻断剂通过在阻断的同时促进孔开放来促进K+通道电流PMID:日期:2026-11-02Many drugs that block voltage-gated K+ channels encoded by the human ether-à-go-go-related gene (hERG) can cause long QT syndrome and life-threatening cardiac arrhythmias, yet the molecular mechanisms…
-
8. Diastolic contributors in cardiomyocytes of a cardiometabolic HFpEF-like mouse model.
PMID:日期:2026-11-02Three main contributors to cardiomyocyte diastolic stiffness are (1) passive sarcomere stiffness, (2) microtubules, and (3) diastolic crossbridges (XBs), the XBs that are present in the diastolic phas…
-
9. Characterization of an open-channel structure and lateral conduction pathway in the cation-selective pentameric ligand-gated ion channel, ELIC.
PMID:日期:2026-09-07Open-channel structures of multiple pentameric ligand-gated ion channels (pLGICs) have been determined, including the prokaryotic model pLGIC, Erwinia ligand-gated ion channel (ELIC). For many of thes…
-
10. A ratiometric ER calcium sensor for quantitative comparisons across cell types and subcellular regions.
PMID:日期:2026-09-07The ER is an important regulator of Ca2+ in cells and dysregulation of ER Ca2+ homeostasis can lead to numerous pathologies. Understanding how various pharmacological and genetic perturbations of ER C…