APPLIED PHYSICS LETTERS应用物理快报
APPLIED PHYSICS LETTERS(英文缩写 APPL PHYS LETT),ISSN 0003-6951,eISSN 1077-3118,中文译名:应用物理快报 是一本学术期刊。本页汇总该期刊的最新影响因子、分区信息以及最新收录于 PubMed 的文献,帮助您快速了解期刊全貌。
发文量统计区间：2025-11-01 至 2026-10-31，按本站收录文献的发表日期统计。
期刊介绍
历年影响因子趋势
| JCR 数据年份 | 影响因子 | JCR 分区 |
|---|---|---|
| 2021 | 3.971 | Q2 |
| 2022 | 4.000 | Q2 |
| 2023 | 3.500 | Q2 |
| 2024 | 3.600 | Q2 |
| 2025 | 3.800 | Q2 |
APPLIED PHYSICS LETTERS 最新收录文献
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1. Shape-optimized Model-based Reconstruction Algorithm for Radiacoustic Imaging.
1. 用于放射声成像的形状优化基于模型的重建算法PMID:日期:2026-06-22[中文摘要] 我们提出了一种基于形状优化的模型重建框架（shape-optimized model-based, SOMB），用于解决放射声成像中因探测器布置受限而导致的有限视角问题，该问题会产生严重病态的逆问题，并在重建图像中表现为特征性伪影。我们首先采用基于参数化水平集的形状优化方法重建近似剂量区域边界，随后仅在该形状约束区域内进行逐点的基于模型剂量重建。通过将重建范围从整个成像域限制在已识别区域内的像素，未知数数量显著减少，从而将严重病态的逆问题转化为约束条件显著改善的问题。我们通过计算研究和实验对该方法进行了验证，实验采用临床X射线和质子放射源，在有限角度覆盖的数据采集条件下进行。结果表明，与标准基于模型的重建相比，该方法显著减少了伪影并提高了准确性，在不同成像设置下相关系数提升了3%至25%，且在有限视角条件更强时改善更为明显。这种形状优化方法为在临床实际探测器配置下实现准确的放射治疗监测提供了一条可行途径。
[英文摘要] We present a shape-optimized model-based (SOMB) reconstruction framework that addresses the limited-view problem in radiacoustic imaging arising from restricted detector placement, which creates severely ill-posed inverse problems that manifest as characteristic artifacts in reconstructed images. We first reconstruct the approximate dose-region boundary using a parametric level set-based shape optimization. Pointwise model-based dose reconstruction is then performed only within this shape-constrained region. By restricting reconstruction from the full imaging domain to only the pixels within the identified region, the number of unknowns is significantly reduced, transforming a severely ill-posed inverse problem into a significantly better-constrained one. We validate this methodology through computational studies and experiments using clinical X-ray and proton radiation sources under limited angular coverage data acquisition settings. Results demonstrate substantial artifact reduction and improved accuracy compared to standard model-based reconstructions, with 3-25% improvement in correlation coefficients across different imaging settings-more pronounced improvements occurring under stronger limited-view conditions. This shape-optimized approach provides a viable pathway for accurate radiation therapy monitoring under clinically realistic detector configurations.
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2. 3D protoacoustic radiography: A proof of principle study.
2. 3D原声放射摄影：原理验证研究PMID:日期:2025-02-17We propose protoacoustic radiography (PAR), an imaging modality combining proton excitation and acoustic detection for three-dimensional (3D) imaging from a single proton projection. PAR avoids the effect of multiple Coulomb scattering in imaging by detecting ultrasound. Proton-induced acoustic waves propagate spherically, enabling 3D imaging from a single projection. Additionally, the distinctive feature of proton beams-concentrating energy deposition primarily at the Bragg peak-allows for precise depth-selectivity through proton energy tuning. We performed PAR using clinical proton machines, and our results demonstrate the capability of PAR to reconstruct targets at various depths (between ∼20 and 23 cm) with an axial resolution of 1.3 mm by fully leveraging the Bragg peak and by tuning the kinetic energy of the proton beam. PAR offers opportunities for precise structural determination with protons both in biomedicine and nondestructive testing.
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3. Non-contact electroacoustic tomography with optical interferometer for electroporation therapy monitoring.
3. 用于电穿孔治疗监测的基于光学干涉仪的非接触式电声层析成像PMID:日期:2025-01-13Electroacoustic imaging is an imaging modality used to detect electric field energy distribution during electroporation, offering valuable guidance for clinical procedures, particularly in deep tissues. Traditionally, single-element piezoelectric transducers or arrays have been employed for this purpose. However, these piezoelectric sensors are sensitive to electromagnetic interference and require physical contact with the sample through a coupling medium, raising concerns for both clinical and preclinical applications. To overcome these limitations, a multi-channel random quadrature ultrasonics system has been developed, enabling non-contact detection of electroacoustic signals. In this study, we demonstrated that this non-contact technique effectively detects electroacoustic signals, identifies electroporation regions, and reconstructs electric energy distribution, offering a promising approach for monitoring electroporation therapy.
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4. ATP-induced reconfiguration of the micro-viscoelasticity of cardiac and skeletal myosin solutions.
PMID:日期:2024-10-21We study the high-frequency, micro-mechanical response of suspensions composed of cardiac and skeletal muscle myosin by optical trapping interferometry. We observe that in low ionic strength solutions, upon the addition of magnesium adenosine triphosphate (MgATP), myosin suspensions radically change their micro-mechanics properties, generating a viscoelastic fluid characterized by a complex modulus similar to a suspension of worm-like micelles. This transduction of energy, from chemical to mechanical, may be related to the relaxed states of myosin, which regulate muscle contractility and can be involved in the etiology of many myopathies. Within an analogous generic mechanical response, cardiac and skeletal myosin suspensions provide different stress relaxation times, elastic modulus values, and characteristic lengths. These discrepancies probably rely on the dissimilar physiological functions of cardiac and skeletal muscle, on the different MgATPase hydrolysis rates of cardiac and skeletal myosins, and on the observed distinct cooperative behavior of their myosin heads in the super-relaxed state. studies like these allow us to understand the foundations of muscle cell mechanics on the micro-scale, and may contribute to the engineering of biological materials whose micro-mechanics can be activated by energy regulators.
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5. Neural network-enabled, all-electronic control of non-Newtonian fluid flow.
5. 神经网络赋能的全电子控制非牛顿流体流动PMID:日期:2024-10-14Real-time, all-electronic control of non-Newtonian fluid flow through a microscale channel is crucial for various applications in manufacturing and healthcare. However, existing methods lack the sensitivity required for accurate measurement and the real-time responsiveness necessary for effective adjustment. Here, we demonstrate an all-electronic system that enables closed-loop, real-time, high-sensitivity control of various waveforms of non-Newtonian fluid flow (0.76 l min) through a micro-sized outlet. Our approach combines a contactless, cuff-like flow sensor with a neural-network control program. This system offers a simple, miniaturized, versatile, yet high-performance solution for non-Newtonian fluid flow control, easily integrated into existing setups.
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6. Impedance matching in optically induced dielectrophoresis: Effect of medium conductivity on trapping force.
6. 光诱导介电泳中的阻抗匹配：介质电导率对捕获力的影响PMID:日期:2024-07-29An impedance analysis for optically induced dielectrophoresis is presented. A circuit model is developed for this purpose. The model parameters are fully defined in terms of the geometrical and material properties of the system. It is shown that trapping force can only be generated when the material properties follow certain impedance matching conditions. The factor is introduced to succinctly quantify the phenomenon. It is used to calculate bounds on the allowed electrical conductivity of the suspension medium. Results from the proposed model are found to be in good agreement with full-wave numerical simulations. By computing the acceptable set of material parameters with little computational cost, the presented analysis can streamline ODEP system design for various applications.
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7. Perspectives on endoscopic functional photoacoustic microscopy.
7. 内窥镜功能光声显微成像的展望PMID:日期:2024-07-15Endoscopy, enabling high-resolution imaging of deep tissues and internal organs, plays an important role in basic research and clinical practice. Recent advances in photoacoustic microscopy (PAM), demonstrating excellent capabilities in high-resolution functional imaging, have sparked significant interest in its integration into the field of endoscopy. However, there are challenges in achieving functional PAM in the endoscopic setting. This Perspective article discusses current progress in the development of endoscopic PAM and the challenges related to functional measurements. Then, it points out potential directions to advance endoscopic PAM for functional imaging by leveraging fiber optics, microfabrication, optical engineering, and computational approaches. Finally, it highlights emerging opportunities for functional endoscopic PAM in basic and translational biomedicine.
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8. A 64-pixel mid-infrared single-photon imager based on superconducting nanowire detectors.
PMID:日期:2024-01-25A large-format mid-infrared single-photon imager with very low dark count rates would enable a broad range of applications in fields like astronomy and chemistry. Superconducting nanowire single-photon detectors (SNSPDs) are a mature photon-counting technology as demonstrated by their figures of merit such as high detection efficiencies and very low dark count rates. However, scaling SNSPDs to large array sizes for mid-infrared applications requires sophisticated readout architectures in addition to superconducting materials development. In this work, an SNSPD array design that combines a thermally coupled row-column multiplexing architecture with a thermally coupled time-of-flight transmission line was developed for mid-infrared applications. The design requires only six cables and can be scaled to larger array sizes. The demonstration of a 64-pixel array shows promising results for wavelengths between 3.4 μm and 10 μm, which will enable the use of this single-photon detector technology for a broad range of new applications.
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9. Measuring the permittivity of fused silica with planar on-wafer structures up to 325 GHz.
PMID:日期:2024Fused silica has become an interesting alternative to silicon for millimeter-wave (mmWave) applications. Unfortunately, there are a few reports on the measurement of fused silica's permittivity above 110 GHz that use electrical rather than optical methods. Given that mmWave applications use electrical circuits, additional electrical data would be useful to industry. To test the feasibility of electrical methods, we applied on-wafer techniques based on coplanar waveguide transmission lines to measure the complex permittivity of fused silica to 325 GHz. Our approach used the multiline thru-reflect-line algorithm on the scattering parameter measurements of transmission lines. Our method combined these results with dc measurements of the resistivity of the metals, simulations of the coplanar waveguide cross section, and dimensional metrology. In short, our measurements do not show significant dielectric dispersion for fused silica up to 325 GHz. The resulting complex permittivity was and a loss tangent from 320 MHz to 325 GHz. To support our conclusions, we performed an uncertainty analysis considering relevant sources of uncertainty. In the broader context, these results show that fused silica is a suitable substrate for mmWave electronics where the loss tangent must be less than 0.005 up to 325 GHz.
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10. AC metrology applications of the Josephson effect.
PMID:日期:2024The performance of programmable voltage signals that exploit the quantum behavior of superconducting Josephson junctions continues to improve and enhance measurements in metrology, communications, and quantum control. We review advances in pulse-driven digital synthesis techniques with Josephson-junction-based devices. Quantum-based synthesis of voltage waveforms has been demonstrated at frequencies up to 3 GHz and rms amplitudes up to 4 V. Josephson pulse generators have also been used to control and characterize superconducting qubits.