AMERICAN JOURNAL OF CARDIOLOGY美国心脏病学杂志
AMERICAN JOURNAL OF CARDIOLOGY(英文缩写 AM J CARDIOL),ISSN 0002-9149,eISSN 1879-1913,中文译名:美国心脏病学杂志 是一本学术期刊。本页汇总该期刊的最新影响因子、分区信息以及最新收录于 PubMed 的文献,帮助您快速了解期刊全貌。
发文量统计区间：2025-09-27 至 2026-09-27，按本站收录文献的发表日期统计。
期刊介绍
历年影响因子趋势
| JCR 数据年份 | 影响因子 | JCR 分区 |
|---|---|---|
| 2021 | 3.133 | Q3 |
| 2022 | 2.800 | Q3 |
| 2023 | 2.300 | Q2 |
| 2024 | 2.100 | Q3 |
| 2025 | 2.500 | Q2 |
AMERICAN JOURNAL OF CARDIOLOGY 最新收录文献
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2. Outcome-linked Left Internal Mammary Artery to Left Anterior Descending Artery Graft Flow Threshold and Quantitative Flow Ratio-based Low-flow Prediction in Off-pump Coronary Artery Bypass Grafting.
PMID:日期:2026-10-01Transit-time flow measurement (TTFM) is used during coronary artery bypass grafting (CABG), but outcome-linked thresholds for low left internal mammary artery-left anterior descending artery (LIMA-LAD) mean graft flow (MGF) and preoperative low-flow predictors remain limited. This single-center retrospective study included 282 patients undergoing elective off-pump CABG with LIMA-LAD grafting. Restricted cubic spline and segmented regression examined the association between MGF and peak high-sensitivity cardiac troponin I (hs-cTnI) within 48 hours, and logistic regression evaluated associations with in-hospital major adverse cardiac and cerebrovascular events (MACCE) and developed a preoperative low-flow prediction model. LIMA-LAD MGF showed a nonlinear association with peak hs-cTnI, with an inflection point at 31 ml/min. Flow <31 ml/min was associated with higher hs-cTnI levels and higher adjusted in-hospital MACCE risk in the main model (34 events; adjusted odds ratio [OR] 2.53, 95% confidence interval [CI] 1.21 to 5.44; p = 0.014). In a sensitivity model additionally adjusted for obtuse marginal/left circumflex-territory grafting, the association was attenuated but remained directionally consistent (OR 2.10, 95% CI 0.99 to 4.46; p = 0.053). Higher LAD quantitative flow ratio (QFR) and smaller distal vessel diameter independently predicted low flow. In conclusion, a LIMA-LAD MGF threshold of 31 ml/min was associated with greater perioperative myocardial injury and higher in-hospital event risk, and a QFR-based model may support perioperative risk stratification pending external validation with standardized 30-day outcomes.
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3. Transvalvular Flow Rate is Associated With Mortality Rate and Lifetime Loss in Aortic Valve Stenosis: A Meta-Analysis of Reconstructed Time-to-Event Data.
PMID:日期:2026-10-01Low-flow states are associated with adverse outcomes in aortic stenosis (AS), but the prognostic value of transvalvular flow rate (TFR) has not been consistently established across studies. This study is a systematic review and meta-analysis of reconstructed time-to-event data was performed in accordance with Preferred Reporting Items for Systematic Reviews and Meta-analyses. PubMed/MEDLINE, EMBASE, and Cochrane Library were searched for studies (published by November 14, 2025) comparing low versus normal TFR in AS. Data were collected from Kaplan-Meier curves. The primary endpoint was all-cause mortality. Survival was assessed using pooled Kaplan-Meier curves, Cox regression, flexible parametric survival models, and restricted mean survival time (RMST) analysis. A total of 9 studies including 6,494 patients were analyzed; 2,575 (39.7%) had low TFR. At 8 years of follow-up, estimated survival was 34.1% (95% confidence interval [CI] 24.7% to 47%) in the low-TFR group and 63% (95% CI 58.9% to 67.4%) in the normal-TFR group. Low TFR was associated with higher all-cause mortality (hazard ratio 1.59, 95% CI 1.45 to 1.74, p < 0.001). We observed a progressively greater hazard over time, with the hazard ratio approaching 1.9 by 8 years. At 8 years, RMST in the normal-TFR group was 7.37 years (95% CI 7.21 to 7.53 years) versus 5.07 years (95% CI 4.91 to 5.23 years) in the low-TFR group, representing a lifetime loss of 2.3 years in the low-TFR group (ΔRMST -2.30 years, 95% CI -2.53 to -2.07 years, p < 0.001). In patients with AS, low TFR is associated with significantly higher mortality and lifetime loss. These findings support TFR as a clinically meaningful marker for risk stratification in AS.
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4. Impact of Chronic Kidney Disease Stage on In-Hospital Bleeding and Mortality in Percutaneous Left Ventricular Assist Device Recipients: A Nationwide Perspective.
PMID:日期:2026-10-01Bleeding events have been reported as a complication of percutaneous left ventricular assist devices (pLVAD). While chronic kidney disease (CKD) independently increases bleeding risk, the impact of worsening CKD stages on bleeding outcomes following pLVAD implantation remains poorly characterized. Therefore, we sought to evaluate the impact of CKD severity gradient on major bleeding and in-hospital mortality among adults undergoing pLVAD implantation. The National Inpatient Sample was queried from 2016 to 2021. Adults undergoing pLVAD implantation were stratified into 6 cohorts: no CKD, CKD stages 1 to 2, stage 3, stage 4, stage 5, and end-stage renal disease (ESRD). Multivariable logistic regression was used to estimate adjusted odds ratios (aORs) of major bleeding, in-hospital mortality, and secondary outcomes. A cohort of 130,620 pLVAD hospitalizations was identified, of which 72.9% had no CKD, 2.0% had CKD stages 1 to 2, 14.1% had CKD stage 3, 3.0% had CKD stage 4, 0.4% had CKD stage 5, and 7.6% had ESRD. Following adjustment, CKD stages 1 to 5 showed no significant association with major bleeding. In contrast, ESRD was independently associated with increased odds of mortality (aOR 1.25; 95% CI 1.63-2.25, p <0.001), major bleeding (aOR, 1.45; 95% CI 1.23-1.65; p <0.001) and specific bleeding types including gastrointestinal bleeding (aOR 1.92; 95% CI 1.63-2.25) and intra-abdominal bleeding (aOR 1.81; 95% CI 1.18-2.78). In conclusion, ESRD represents a high-risk phenotype characterized by significantly increased major bleeding and in-hospital mortality. Major bleeding is driven by site-specific hemorrhage, including gastrointestinal, intra-abdominal, and pericardial bleeding. Risk stratification and targeted anticoagulation strategies are necessary for this vulnerable population.
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5. Tomography Versus Angiography for Coronary Stenoses Before Transcatheter Aortic Valve Implantation.
PMID:日期:2026-10-01Coronary artery disease is common in patients undergoing transcatheter aortic valve implantation (TAVI), but the optimal preprocedural coronary assessment strategy is uncertain. We compared long-term outcomes of a computed tomography angiography (CTA)-first versus an invasive coronary angiography (ICA)-first strategy in 307 consecutive patients undergoing TAVI at a single center (ICA-first, n = 150; CTA-first, n = 157). The primary outcome was all-cause mortality. Over a median follow-up of 61.7 months, mortality did not differ between strategies (unadjusted hazard ratio [HR] 0.88, 95% confidence interval [CI] 0.66-1.16), and assessment strategy was not an independent predictor of death after adjustment (HR 0.95, 95% CI 0.67-1.34). A CTA-first strategy avoided invasive angiography in 73% of patients, with a nonsignificant trend toward more late post-TAVI catheterization (HR 2.47, 95% CI 0.94-6.45). Pre-TAVI percutaneous coronary intervention was not associated with lower mortality, although coronary artery disease itself identified a higher-risk phenotype. In conclusion, a CTA-first strategy yielded equivalent long-term survival while sparing most patients invasive angiography, supporting its use as the default pre-TAVI coronary assessment strategy.
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6. Chronic Kidney Disease Stage-specific Risk and Clinical Presentation in Left Main Coronary Intervention: Insights from the LM-JANHO Registry.
6. 左主干冠状动脉介入治疗中慢性肾病分期特异性风险和临床表现：来自LM-JANHO登记处的见解PMID:日期:2026-10-01The impact of chronic kidney disease (CKD) stage on outcomes after percutaneous coronary intervention (PCI) for left main (LM) coronary artery disease remains unclear. We investigated the impact of CKD stage on long-term outcomes after contemporary LM-PCI. We analyzed 756 consecutive patients who underwent LM-PCI for de novo lesion under intracoronary imaging-guidance across 19 hospitals. Patients were categorized by CKD stage: I/II (n = 360), IIIa (n = 212), IIIb (n = 105), IV (n = 40), and V (n = 39). Three-year major adverse cardiovascular and cerebrovascular events (MACCE), including all-cause death, clinically driven revascularization, myocardial infarction, and cerebrovascular events, were evaluated. Patients with CKD stage IIIb or worse had higher comorbidity burdens than those with CKD I/II, including high age, hypertension, peripheral artery disease, and reduced left ventricular ejection fraction. Patients with CKD-IIIb and -IV presented more acute coronary syndrome and required mechanical circulatory support, whereas these frequencies in CKD-V were similar as in CKD-I/II. In contrast, CKD V patients exhibited greater lesion complexity, with more true bifurcation lesion and calcified lesions needing atherectomy. MACCE rates were significantly higher in CKD IV and V (CKD-I/II: 28.9%, IIIa: 31.3%, IIIb: 35.7%, IV: 45.8%, V: 48.7%). All-cause mortality rose stepwise with worsening CKD (CKD-I/II: 8.4%, IIIa: 14.9%, IIIb: 24.2%, IV: 34.9%, V: 34.6%). Clinically driven revascularization rates did not increase with advancing CKD stage. In conclusion, advanced CKD was associated with progressively worse clinical outcomes after contemporary LM-PCI, primarily driven by increased mortality, whereas clinically driven revascularization did not increase with CKD severity despite greater lesion complexity.
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7. A Composite Echocardiographic Index of Global Cardiac Remodeling in Athletes: Global Athletic Heart Index (GAHI).
PMID:日期:2026-10-01Elite athletes develop physiological cardiac remodeling, involving both ventricular and atrial chambers, as well as wall thickening. We propose a Global Athletic Heart Index (GAHI) which integrates both ventricular and atrial changes, aiming to define with a simplified marker the physiologic cardiac remodeling and its relationship with aerobic performance in athletes. Six hundred forty-one healthy Olympic athletes (mean age 25.5 ± 5.3 years; 51% male) underwent transthoracic echocardiography and cardiopulmonary exercise testing. GAHI was calculated as the mean ratio of each chamber dimension to its sex-specific upper limit of normal. Athletes were classified as GAHI >1 (global cardiac remodeling) or ≤1. VO₂ max >85% of predicted was considered and indicator of preserved aerobic capacity. Sensitivity, specificity, and predictive values of GAHI >1 for identifying preserved VO₂ max were evaluated. Linear regression analyses assessed the association of GAHI with peak VO₂ and O₂ pulse. Overall, 155 athletes (24.2%) had GAHI >1. Endurance athletes were overrepresented in this group (51% vs 13%, p <0.0001). GAHI >1 was associated with larger LV and RV dimensions, higher LV mass, balanced biatrial enlargement, and preserved systolic and diastolic function. Cardiopulmonary exercise testing revealed higher peak VO₂, O₂ pulse, and workload (all p <0.0001). Linear regression analyses demonstrated significant positive associations between GAHI and peak VO₂ (R² = 0.24, p <0.0001) and O₂ pulse (R² = 0.20, p <0.0001). Using a dichotomous threshold, GAHI >1 identified athletes with VO₂ max >85% with 25.7% sensitivity, 93.9% specificity, 98.1% positive predictive value, and 9.5% negative predictive value. GAHI is an integrative marker of balanced cardiac remodeling closely associated with aerobic performance. A GAHI >1 reliably identifies athletes with balanced structural adaptations and preserved exercise capacity. GAHI may serve as a practical tool for athlete screening and individualized cardiovascular assessment.
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8. Sex Differences in Clinical Outcomes After Bifurcation Percutaneous Coronary Intervention: Findings from the PROGRESS-BIFURCATION Registry.
8. 分叉经皮冠状动脉介入治疗后临床结果的性别差异：来自PROGRES-Bifurcation登记的发现PMID:日期:2026-10-01Sex differences in the outcomes of bifurcation percutaneous coronary intervention (PCI) have received limited study. We compared the procedural characteristics and outcomes between women and men in bifurcation PCI. Two thousand four hundred thirty-one patients who underwent bifurcation PCI at 7 centers between 2013 and 2025 from the Prospective Global Registry for the Study of Bifurcation Lesion Interventions were studied. Of the study population, 25.3% (n = 615) were women. Women were older (68.2 ± 11.9 vs 65.6 ± 16.3 years; p <0.001), had higher prevalence of diabetes mellitus (48.8% vs 33.5%; p <0.001), hypertension (84.2% vs 76.9%; p <0.001), and higher rates of moderate or severe proximal main vessel calcification (40.2% vs 32.4%; p <0.001) compared with men. Use of provisional stenting (63.2% vs 64.0%, p = 0.694) and two-stent techniques (31.3% vs 30.3%, p = 0.653) was similar between groups. Technical success was comparable (93.7% vs 95.4%; p = 0.075), but women had lower procedural success (88.5% vs 93.2%; p <0.001) due to higher in-hospital major adverse cardiovascular events (MACE) (6.0% vs 2.7%; p <0.001), including in-hospital mortality (2.8% vs 1.0%; p = 0.001), stroke (1.3% vs 0.2%; p = 0.003), and procedural bleeding (1.0% vs 0.2%; p = 0.010). On multivariable analysis, female sex was independently associated with higher in-hospital MACE (odds ratio 2.99; 95% confidence intervals 1.69 to 5.29; p <0.001). During a median follow-up of 2.6 years, female sex was independently associated with long-term MACE (adjusted hazard ratio 1.32; 95% confidence intervals 1.04 to 1.67; p = 0.011). In conclusion, compared with men, bifurcation PCI in women is associated with similar technical success but higher in-hospital and adjusted follow-up MACE.
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9. Outflow Tract Premature Ventricular Complex Induced Cardiomyopathy: A Narrative Review.
PMID:日期:2026-10-01Frequent premature ventricular complexes (PVCs) are well known to impair left ventricular systolic function. However, most patients with frequent PVCs do not develop cardiomyopathy. We review the various predictors and mechanisms of PVCs that lead to cardiomyopathy, with an emphasis on right ventricular outflow tract PVC-induced left ventricular dyssynchrony and diastolic dysfunction. The variable myocardial susceptibility to PVCs may be due to an undiagnosed subclinical cardiomyopathy. Advanced imaging modalities and genetic screening may help identify primary cardiomyopathic processes. Radiofrequency ablation to reduce PVC burden can not only improve both systolic and diastolic function but also reverse left ventricular remodeling and enhance quality of life.