细菌需氧性：受体多样性、信号转导和生态功能
Bacterial aerotaxis: receptor diversity, signal transduction and ecological functions.
摘要(中文译文)
趋氧性（aerotaxis）是一种与细菌能量代谢内在相关的氧定向运动行为，是包括细菌和古菌在内的运动型原核生物的基本生存与适应策略。该行为使这些微生物能够沿氧气梯度运动并定殖于代谢最优的生态位。本文系统综述了细菌趋氧性研究的最新进展，重点阐述了趋氧性受体的多样化信号感知机制，主要分为能量依赖型和直接氧感知型两类。此外，我们阐明了其氧信号感知与转导所依据的独特分子机制。我们还讨论了趋氧性的两种主要适应性调控机制及其在介导微生物-宿主互作、促进宿主定殖和调节生物膜形成中的关键生态功能。本工作阐明了趋氧性在原核生物环境适应中的进化与生态意义，并为未来相关研究提供了全面的理论框架。
Abstract
Aerotaxis, the oxygen-directed motile behavior intrinsically linked to bacterial energy metabolism, serves as a fundamental survival and adaptive strategy for motile prokaryotes, including bacteria and archaea. This behavior enables these microorganisms to navigate along oxygen gradients and colonize metabolically optimal ecological niches. This review systematically synthesizes the latest research advancements in bacterial aerotaxis, focusing on the diverse signal-sensing mechanisms of aerotaxis receptors, which are primarily categorized into energy-dependent and direct oxygen-sensing types. Furthermore, we elucidate the distinct molecular mechanisms that underlie their oxygen signal perception and transduction. We also discuss the two major adaptive regulatory mechanisms of aerotaxis and its critical ecological functions in mediating microbe-host interactions, facilitating host colonization, and modulating biofilm formation. This work clarifies the evolutionary and ecological significance of aerotaxis in prokaryotic environmental adaptation and provides a comprehensive theoretical framework for future relevant research.
如何引用
AMA
Zhiwei Huang, Wanpeng Zhang, Chengning Qin, Hongliang Zhao, Feiyu Yan, Guoliang Zhang. Bacterial aerotaxis: receptor diversity, signal transduction and ecological functions.. PeerJ. 2026; doi:10.7717/peerj.21573.
APA
Zhiwei Huang, Wanpeng Zhang, Chengning Qin, Hongliang Zhao, Feiyu Yan, Guoliang Zhang (2026). Bacterial aerotaxis: receptor diversity, signal transduction and ecological functions.. PeerJ. https://doi.org/10.7717/peerj.21573
GB/T 7714
Zhiwei Huang, Wanpeng Zhang, Chengning Qin, Hongliang Zhao, Feiyu Yan, Guoliang Zhang. Bacterial aerotaxis: receptor diversity, signal transduction and ecological functions.[J]. PeerJ, 2026 doi:10.7717/peerj.21573.
在 PubMed增强版 阅读全文
翻译全文 · AI 文献问答 · PDF 原文下载 · 引用导出