不同饮料消费与炎症性肠病风险之间的关联：剂量反应荟萃分析
Association between different drinks consumption and risk of inflammatory bowel disease: a dose-response meta-analysis.
摘要(中文译文)
系统综述并整合日常生活中不同饮品摄入与炎症性肠病（IBD）风险之间关系的证据。我们系统检索了PubMed、Web of Science、SinoMed、Cochrane Library、Embase、Wiley、CNKI和万方数据库，纳入探讨饮料摄入与IBD关系的病例对照研究、队列研究和横断面研究。采用随机效应模型进行荟萃分析。共纳入来自16个地区的27篇文章。荟萃分析显示，软饮料摄入与IBD风险增加相关（OR=1.144，95% CI：1.052-1.243，=0.002）。相反，酒精摄入（OR=0.793，95% CI：0.629-0.999，=0.049）、咖啡摄入（OR=0.807，95% CI：0.667-0.976，=0.027）和茶摄入（OR=0.711，95% CI：0.522-0.970，=0.031）与IBD风险降低相关。剂量反应分析显示，酒精（线性趋势=0.011）和咖啡（线性趋势<0.001）摄入与IBD风险呈线性负相关。对于茶摄入，饮茶频率（次/周）与IBD风险之间发现显著的非线性关系及下降趋势（非线性趋势<0.001）。IBD风险在每周1.200至6.000次的范围内呈缓慢上升趋势。软饮料摄入与IBD风险相关。当前证据提示，较高的咖啡、酒精和茶摄入与IBD风险降低相关；然而，鉴于某些饮料的研究数量有限、异质性较高，且现有文献以病例对照设计为主，仍需进一步的前瞻性研究来证实这些发现。https://inplasy.com/，标识符INPLASY（注册号INPLASY2025120094）。
Abstract
To systematically review and synthesize the evidence between consumption of different drinks in daily life and the risk of Inflammatory bowel disease (IBD). We systematically searched PubMed, Web of Science, SinoMed, Cochrane Library, Embase, Wiley, CNKI, and Wanfang Database for case-control, cohort, and cross-sectional studies investigating the relationship between beverage intake and IBD. A random-effects model was used for the meta-analysis. A total of 27 articles from 16 regions were included. The meta-analysis showed that soft beverage intake was associated with an increased risk of IBD (OR = 1.144, 95% CI: 1.052-1.243, = 0.002). In contrast, alcohol intake (OR = 0.793, 95% CI: 0.629-0.999, = 0.049), coffee intake (OR = 0.807, 95% CI: 0.667-0.976, = 0.027), and tea intake (OR = 0.711, 95% CI: 0.522-0.970, = 0.031) were associated with a reduced risk of IBD. Dose-response analysis revealed a linear inverse correlation between alcohol (linear trend = 0.011) and coffee (linear trend < 0.001) consumption and IBD risk. For tea consumption a significant nonlinear relationship and a downward trend was found between tea consumption frequency (times/week) and IBD risk (nonlinear trend < 0.001). The risk of IBD showed a slow upward trend within the range of 1.200 to 6.000 times per week. Soft beverage consumption is associated with the risk of IBD. Current evidence suggests that higher intake of coffee, alcohol, and tea is associated with a reduced risk of IBD; however, further prospective studies are needed to confirm these findings, given the limited number of studies for certain beverages, highly heterogeneity, and the predominance of case-control designs in the current literature. https://inplasy.com/, identifier INPLASY (registration number INPLASY2025120094).
如何引用
AMA
Yu Jie Peng, Yu Zeng, Ding Niu Li, Ke Xi Wei, Min Li. Association between different drinks consumption and risk of inflammatory bowel disease: a dose-response meta-analysis.. Frontiers in nutrition. 2026; doi:10.3389/fnut.2026.1817418.
APA
Yu Jie Peng, Yu Zeng, Ding Niu Li, Ke Xi Wei, Min Li (2026). Association between different drinks consumption and risk of inflammatory bowel disease: a dose-response meta-analysis.. Frontiers in nutrition. https://doi.org/10.3389/fnut.2026.1817418
GB/T 7714
Yu Jie Peng, Yu Zeng, Ding Niu Li, Ke Xi Wei, Min Li. Association between different drinks consumption and risk of inflammatory bowel disease: a dose-response meta-analysis.[J]. Frontiers in nutrition, 2026 doi:10.3389/fnut.2026.1817418.
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