仿生抗菌玻璃涂层用于透明且抗感染的表面
Bioinspired antimicrobial glass coatings for clear and infection-resistant surfaces.
摘要(中文译文)
能够同时防止起雾、抵抗污染并消除微生物生长的光学透明玻璃表面，在医用光学器件、防护装备及先进建筑应用中具有极高的需求。在持续视觉清晰度和抗微生物定植能力对诊断准确性和患者安全至关重要的应用中，以及在可减少用水量和化学表面活性剂依赖的自清洁玻璃面板中，多功能表面涂层备受青睐。在此，我们报道了一种受贻贝启发的单步浸涂策略，通过共价固定将多巴胺偶联季铵抗菌聚合物（DQP）接枝到玻璃基底上，为多功能表面工程提供了一条稳健且可规模化的途径。原子力显微镜（AFM）显示涂层为均匀的纳米级形貌，在Wenzel润湿状态下呈现超亲水性。改性表面表现出显著的超亲水性（接触角约3-4°），同时保持高可见光透明度，从而实现有效的防雾性能。该涂层还展现出自我清洁行为，通过简单的水冲洗即可有效去除疏水性颗粒。重要的是，当涂层浓度超过某一阈值时，表面对革兰氏阳性菌、革兰氏阴性菌以及耐药真菌菌株均显示出强效的抗菌活性。该涂层在反复洗涤循环及不同温度条件下均能保持结构完整性和功能性能，凸显了其耐久性以及在生物医学和防护实际应用中的强大潜力。
Abstract
Optically transparent glass surfaces that simultaneously prevent fogging, resist contamination, and eliminate microbial growth are highly desirable for medical optics, protective equipment, and advanced architectural applications. In applications where sustained visual clarity and resistance to microbial colonization are critical for diagnostic accuracy and patient safety, as well as in self-cleaning glass panels that reduce water consumption and reliance on chemical surfactants, multifunctional surface coatings are highly desirable. Here, we report a mussel-inspired, single-step dip-coating strategy for covalent immobilization of a dopamine-conjugated quaternary antimicrobial polymer (DQP) onto glass substrates, providing a robust, scalable route to multifunctional surface engineering. Atomic force microscopy (AFM) reveals uniform nanoscale coatings, with superhydrophilicity in the Wenzel wetting regime. The modified surfaces exhibit pronounced superhydrophilicity (contact angle of ∼3-4°) while maintaining high visible transparency, enabling effective antifogging performance. The coatings further demonstrate self-cleaning behaviour by efficiently removing hydrophobic particulates upon simple water rinsing. Importantly, above a threshold coating concentration, the surfaces display potent antimicrobial activity against Gram-positive and Gram-negative bacteria as well as drug-resistant fungal strains. The coatings retain structural integrity and functional performance after repeated washing cycles and across varying temperature conditions, underscoring their durability and strong potential for practical biomedical and protective applications.
如何引用
AMA
Subhankar Maity, Arup Sarkar, Arindam Patra, Joy Mitra, Jayanta Haldar. Bioinspired antimicrobial glass coatings for clear and infection-resistant surfaces.. Journal of materials chemistry. B. 2026; doi:10.1039/d6tb00465b.
APA
Subhankar Maity, Arup Sarkar, Arindam Patra, Joy Mitra, Jayanta Haldar (2026). Bioinspired antimicrobial glass coatings for clear and infection-resistant surfaces.. Journal of materials chemistry. B. https://doi.org/10.1039/d6tb00465b
GB/T 7714
Subhankar Maity, Arup Sarkar, Arindam Patra, Joy Mitra, Jayanta Haldar. Bioinspired antimicrobial glass coatings for clear and infection-resistant surfaces.[J]. Journal of materials chemistry. B, 2026 doi:10.1039/d6tb00465b.
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