Translational Neurodegeneration
Translational Neurodegeneration(英文缩写 TRANSL NEURODEGENER),ISSN 2047-9158,eISSN 2047-9158 是一本学术期刊。本页汇总该期刊的最新影响因子、分区信息以及最新收录于 PubMed 的文献,帮助您快速了解期刊全貌。
指标来源：jcr_cas_ifqb
期刊简介
暂无简介。
历年影响因子趋势
| 年份 | 影响因子 | JCR 分区 |
|---|---|---|
| - | Q1 | |
| - | Q1 | |
| - | Q1 | |
| - | Q1 | |
| - | Q1 |
Translational Neurodegeneration 最新收录文献
※ 中文译文由 AI 辅助生成,仅供学术参考,请以英文原文为准。
-
Species-dependent activities of the PINK1-parkin axis.
In vitro studies have established that PTEN-induced putative kinase 1 (PINK1) and parkin are central regulators of mitophagy, and loss-of-function mutations in either gene can cause early-onset Parkin…
-
Brain region-resolved pharmacodynamics of an antisense oligonucleotide targeting human SNCA 3'UTR in BAC-hSNCA rats.
Alpha-synuclein accumulation contributes to Parkinson's disease (PD), and lowering α-synuclein expression is a candidate disease-modifying approach. The brain-wide pharmacodynamic profile of human-tar…
-
Human amniotic mesenchymal stromal cell-derived extracellular vesicles reprogram microglia and prevent neurodegeneration in experimental models of Alzheimer's disease.
Alzheimer's disease (AD) is the most prevalent neurodegenerative disorder and disproportionately affects women, with neuroinflammation emerging as a key driver of disease onset and progression. Beyond…
-
Central nervous system lymphatic network: from the maintenance of brain homeostasis to emerging therapeutic perspectives in neurodegenerative diseases.
The brain was long been regarded as an immune-privileged organ with a lack of lymphatic drainage, partly because of the absence of parenchymal lymphatic vessels. This long-held doctrine has been chall…
-
The gut neuroepithelial unit as a neurodegeneration-relevant interface in the gut-brain axis. 肠神经上皮单位作为肠脑轴中与神经变性相关的界面
[中文摘要] 神经退行性疾病越来越多地与肠脑轴的异常有关，但管腔和粘膜扰动与中枢神经系统相关的局部肠道界面仍然不明确。肠道神经上皮单元（GNU）被提出为一种局部的粘膜信号接口，由感觉上皮细胞、肠道神经元、神经胶质细胞和相邻的免疫基质元件组成，用于检测、编码肠道信息并将其传递到神经、内分泌和免疫输出中。该框架将肠道从大脑病理学的弥漫上游调节器转变为介观单位，通过该单位，微生物产物、屏障功能障碍、炎症线索和代谢信号…
-
HSPA8 orchestrates SNARE complex assembly to drive extracellular vesicle-mediated spread of p-tau217 in Alzheimer's disease.
Dysregulation of multivesicular bodies (MVBs) in Alzheimer's disease (AD) contributes to aberrant tau secretion via extracellular vesicles (EVs). This may potentially explain our previous paradoxical …
-
Correction: Neurotrophic factor-α1/carboxypeptidase E regulates critical protein networks to rescue neurodegeneration, defective synaptogenesis and impaired autophagy in Alzheimer's disease mice.
-
Bridging the gap: neuroinflammation and the dawn of precision medicine in amyotrophic lateral sclerosis.
Neuroinflammation is no longer a secondary feature of amyotrophic lateral sclerosis (ALS), but rather a disease-modifying process that actively shapes the motor neuron vulnerability from the earliest …
-
PCSK9 inhibitors in neurodegenerative disorders: mechanisms, therapeutic potential, and clinical implications. 神经退行性疾病中的PCSK9抑制剂：机制、治疗潜力和临床意义
Proprotein convertase subtilisin/kexin type 9 (PCSK9) plays a role in hepatic cholesterol metabolism via low density lipoprotein receptor degradation. PCSK9 inhibitors have revolutionized lipid-loweri…
-
The mitophagy-inflammasome axis: a shared pathological hub in Alzheimer's and Parkinson's diseases.
Alzheimer's disease (AD) and Parkinson's disease (PD) represent the most prevalent chronic neurodegenerative disorders, characterized by progressive loss of neurons as a core pathological feature. Des…