mAbs
mAbs(英文缩写 MABS-AUSTIN),ISSN 1942-0862,eISSN 1942-0870 是一本学术期刊。本页汇总该期刊的最新影响因子、分区信息以及最新收录于 PubMed 的文献,帮助您快速了解期刊全貌。
指标来源：jcr_cas_ifqb
期刊简介
暂无简介。
历年影响因子趋势
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mAbs 最新收录文献
※ 中文译文由 AI 辅助生成,仅供学术参考,请以英文原文为准。
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Quantifying molecular specificity in excipient-driven antibody solubilization.
Excipients are widely used to suppress the self-association of therapeutic proteins, yet their mechanisms of action are not well understood and often assumed to be nonspecific. Here we show that excip…
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DyAb: sequence-based antibody design and property prediction in a low-data regime. DyAb：低数据条件下的基于序列的抗体设计与性质预测
Protein therapeutic design and property prediction are frequently hampered by data scarcity. Here we propose a model, DyAb, that addresses these issues by leveraging a pair-wise representation to pred…
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Mimic antibodies: leveraging ligand mimicry for epitope-targeted antibody discovery.
Antibodies are renowned for their ability to bind diverse targets with high affinity and specificity, yet identifying binders with predefined epitope specificity remains a major challenge. In this stu…
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Glycosylation penetrance of N-X-S/T sequons in antibody variable domains: a structural survey of 19,265 human antibody structures reassessing the histidine/glutamine suppression hypothesis. 抗体可变结构域中N-X-S/T序列的糖基化外显率：对19265个人抗体结构的结构调查，重新评估组氨酸/谷氨酰胺抑制假说
Machine learning (ML) approaches for de novo antibody design generate thousands of candidate sequences, but most lack a robust assessment of post-translational modification liabilities. N-linked glyco…
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A NANOBODY molecule that blocks MerTK ectodomain cleavage in vitro and in vivo. 一种在体外和体内阻断MerTK胞外结构域切割的NANOBODY分子
The membrane receptor MerTK is critical for the resolution of inflammation and thus is of pharmacological interest. MerTK function is inhibited by the proteolytic cleavage of its extracellular domain …
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Predicting antibody self-association with sequence-structure fusion models: the central role of CSI-BLI in early developability screening.
Antibody-based biologics are expanding rapidly, yet challenges in development from self-association, high viscosity, aggregation, and unfavorable clearance underscore the need for accurate in silico s…
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Discovery and optimization of marstacimab, a human monoclonal antibody targeting tissue factor pathway inhibitor for the treatment of hemophilia A and B.
We report the discovery and optimization of marstacimab, a novel monoclonal antibody targeting tissue factor pathway inhibitor (TFPI), for the treatment of hemophilia A and B. Hybridoma and phage disp…
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NMR detects clustering and ultra-weak excipient interactions governing monoclonal antibody viscosity in formulation-relevant conditions.
High-concentration formulations of monoclonal antibodies (mAbs) are required for subcutaneous administration but are frequently challenging to develop due to elevated viscosity and colloidal instabili…
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Combination therapy with a novel CD2-targeted costimulatory bispecific antibody overcomes limitations of CD3 T cell engager treatment for solid tumors.
CD3 T cell engagers (TCEs) have transformed hematologic oncology, but dose-liming toxicity and the absence of adequate costimulation have limited TCE success in solid tumors. Consequently, to date, on…
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The double-edged nature of antibody bivalency: mathematical and experimental analysis of cell surface antigen occupancy and opsonization. 抗体二价性的双刃性：细胞表面抗原占据和调理的数学和实验分析
Monoclonal antibodies are bivalent molecules and are thus able to engage two antigens concurrently, a property termed avidity. The therapeutic efficacy of an antibody drug can be broadly defined as a …