CLINICAL BIOMECHANICS临床生物力学
CLINICAL BIOMECHANICS(英文缩写 CLIN BIOMECH),ISSN 0268-0033,eISSN 1879-1271,中文译名:临床生物力学 是一本学术期刊。本页汇总该期刊的最新影响因子、分区信息以及最新收录于 PubMed 的文献,帮助您快速了解期刊全貌。
发文量统计区间：2025-11-01 至 2026-10-31，按本站收录文献的发表日期统计。
期刊介绍
历年影响因子趋势
| JCR 数据年份 | 影响因子 | JCR 分区 |
|---|---|---|
| 2021 | 2.034 | Q3 |
| 2022 | 1.800 | Q3 |
| 2023 | 1.400 | Q3 |
| 2024 | 1.400 | Q3 |
| 2025 | 1.800 | Q3 |
CLINICAL BIOMECHANICS 最新收录文献
-
1. Hip kinematics are associated with gait speed in knee osteoarthritis: A smartphone-based markerless motion capture study.
1. 髋关节运动学与膝骨关节炎患者的步速相关：一项基于智能手机的无标记运动捕捉研究PMID:日期:2026-09-26Comprehensive evaluation of gait-related factors in patients with knee osteoarthritis remains limited, particularly the contribution of adjacent joint kinematics. Identifying biomechanical and clinical factors associated with gait performance may improve understanding of walking in knee osteoarthritis. This study examined associations between gait speed, clinical factors, and lower-limb joint kinematics. Fifty-eight patients scheduled for surgical treatment were enrolled. Preoperative gait speed and lower-limb joint kinematics during walking were assessed using a smartphone-based markerless motion capture system (OpenCap). The hip and knee range of motion during gait was calculated from the kinematic data. Patient characteristics included age, presence of contralateral knee arthroplasty, and knee extensor muscle strength on the affected side. Multivariable linear regression analysis was performed to identify factors independently associated with gait speed. Greater hip sagittal-plane range of motion (B = 0.0086, 95% CI: 0.003-0.014, p = 0.0009), hip coronal-plane range of motion (B = 0.0090, 95% CI: 0.003-0.015, p = 0.004), and lower-limb muscle strength measured by hand-held dynamometer (B = 0.05, 95% CI: 0.016-0.086, p = 0.005) were independently associated with faster gait speed. Hip kinematic variables collectively explained approximately 35% of the variance in gait speed. The final regression model explained 63% of the variance in gait speed (R = 0.63; adjusted R = 0.59). Hip sagittal- and coronal-plane ROM during walking and knee extensor strength were independently associated with gait speed. These findings highlight the relevance of assessing multi-joint kinematics and muscle strength when characterizing gait performance in individuals with knee osteoarthritis.
-
2. Gait asymmetry phenotypes in subacute stroke: A cluster analysis of spatiotemporal parameters.
PMID:日期:2026-09-25Gait asymmetry is a hallmark of post-stroke walking impairment, yet single-parameter measures may miss distinct multivariate patterns. Whether asymmetry-based phenotypes carry prognostic information independent of baseline clinical severity has not been tested. This retrospective cohort study included 245 individuals with subacute stroke who underwent instrumented walkway gait analysis. Seven variables-six asymmetry indices and leg-length-normalised walking velocity-were entered into k-means clustering. Cluster number was selected by three convergent criteria; stability was assessed by 1000 bootstrap resamples and cross-validation against partitioning around medoids. Functional Ambulation Category at discharge was modelled with cumulative link ordinal regression, with threshold-specific sensitivity analyses. Three clusters were identified (average silhouette width 0.308; bootstrap Jaccard ≥0.918): Cluster 1 (n = 70, "Stance-Phase Compensatory"), Cluster 2 (n = 112, "Near-Symmetric Fast") and Cluster 3 (n = 63, "Swing-Phase Dominant"). Unadjusted change in the Functional Ambulation Category differed among clusters (H = 18.20, ε = 0.067, P < 0.001), but cluster membership was not independently associated with the outcome after adjustment for its baseline value, age, onset time and lower-extremity Motricity Index (Cluster 2: odds ratio 0.94, 95% confidence interval 0.40-2.20; Cluster 3: 0.93, 0.48-1.79). Cluster effects were non-significant at every threshold in sensitivity analyses (all P ≥ 0.11). Three gait asymmetry phenotypes exist in subacute stroke, differentiated by swing-stance phase distribution. Their value appears descriptive-characterising qualitatively different compensation strategies-rather than prognostic; this requires prospective testing.
-
3. Levodopa-induced dyskinesia provokes inflexible head-pelvis coordination during standing in Parkinson's disease.
3. 左旋多巴诱导的运动障碍在帕金森病患者站立时引发头部-骨盆协调僵硬PMID:日期:2026-09-25To achieve postural control, individuals must orient their body segments to each other and maintain equilibrium with gravity. However, levodopa, the standard and most effective medication for the symptomatic treatment of Parkinson's disease (PD), also increases postural sway and head instability in people with levodopa-induced dyskinesia (LID). LID is characterized by involuntary, uncontrollable movements occurring after levodopa intake. This study investigated the effect of LID on body segment coordination while standing in PD. People with PD (13 with LID, 12 without LID) and 10 healthy controls (HC) completed 30-second standing trials in single (quiet standing) and cognitive dual-task conditions. Participants with PD completed these trials both in their practical OFF and ON medication states. We recorded head and pelvis acceleration with body-worn inertial sensors. We then quantified head-pelvis coordination with Joint Recurrence Quantification Analysis, a method sensitive to the coupling between parts of biomechanical systems. In people with PD with LID, head-pelvis coupling was higher in the ON medication state than in the OFF medication state. This effect of medication was not observed in people with PD without LID. When OFF medication, people with PD with LID exhibited lower coupling than HC. This is novel evidence that medication and LID interact to alter multisegmental coordination in people with PD, with potential consequences for balance control.
-
4. A quantitative computed tomography-based finite element analysis of iatrogenic fracture during shoulder dislocation reduction: biomechanical mechanism and efficacy of prophylactic K-wire fixation.
4. 基于定量计算机断层扫描的肩关节脱位复位术中医源性骨折的有限元分析：生物力学机制及预防性克氏针固定的疗效PMID:日期:2026-09-23Iatrogenic fracture during closed reduction of anterior shoulder dislocation with greater tuberosity fracture is a serious complication. This study aimed to quantify its biomechanical risk and evaluate prophylactic Kirschner wire (K-wire) fixation. We retrospectively analyzed 126 patients (age ≥ 50 years). A patient-specific finite element model of the proximal humerus was created from quantitative computed tomography (QCT) data. Parametric models with different greater tuberosity defect sizes (0-40%) were loaded under pure axial traction (300N) or combined (axial 300 N + lateral) loading. A model with two parallel K-wires (2.5 mm) was also analyzed. The clinical incidence of iatrogenic fracture was 0.79%. Finite element analysis showed: (1) Greater tuberosity defects drastically reduced structural load capacity; a 10% defect lowered failure load to <10% of intact. (2) Combined loading reduced failure load by 60-70% versus pure traction. (3) The predicted fracture site was consistently the medial surgical neck. (4) Under combined loading, K-wires gave minimal protection (<5% load increase). Greater tuberosity defects critically weaken the proximal humerus by disrupting the lateral tension band. Lateral reduction stress is the primary biomechanical cause of iatrogenic fracture, against which temporary K-wire fixation offers limited protection. For elderly patients, closed reduction should emphasize gentle axial traction while minimizing lateral lever forces.
-
5. Risk of scoliosis following hip disease: a 10-year nationwide cohort study in South Korea.
5. 髋关节疾病后脊柱侧弯的风险：韩国一项为期10年的全国性队列研究PMID:日期:2026-09-21The biomechanical linkage between the hip and spine suggests that hip disorders may contribute to secondary spinal deformities such as scoliosis, but longitudinal population-based evidence is limited. This study examined the long-term risk of adult scoliosis following different types of hip disorders using a nationwide South Korean cohort. This retrospective matched cohort study used Korean National Health Insurance Service data (2002-2013). Patients with degenerative (n = 5208), inflammatory/infectious (n = 11,215), or traumatic (n = 2765) hip disorders were matched 1:2 to individuals without hip disorders. Incident scoliosis was identified using ICD-10 codes. Adjusted hazard ratios (aHRs) were estimated with multivariable Cox proportional hazards models, with subgroup analyses by age and sex. Over a 10-year follow-up, scoliosis incidence was higher among patients with hip disorders than among controls. The risk was significantly increased in degenerative hip disorders (aHR 2.12, 95% CI 1.61-2.78) and inflammatory/infectious hip disorders (aHR 1.68, 95% CI 1.34-2.11). Traumatic hip disorders showed a non-significant association (aHR 1.49, 95% CI 0.99-2.24). Higher relative risks were generally observed in younger patients and males, particularly in the degenerative hip disorder group. Degenerative and inflammatory/infectious hip disorders are associated with an increased long-term risk of scoliosis. These findings underscore the need for early spinal evaluation and preventive strategies in patients with hip pathology.
-
6. Characterizing accuracy, retention, and dose-response of an 18-session real-time gait biofeedback program following anterior cruciate ligament reconstruction.
6. 前交叉韧带重建术后18次实时步态生物反馈项目的准确性、保持性和剂量-反应特征研究PMID:日期:2026-09-20Individuals following anterior cruciate ligament reconstruction (ACLR) commonly demonstrate aberrant walking biomechanics, characterized by a lesser first peak vertical ground reaction force (vGRF) during early stance. Gait biofeedback may address this deficit; however, the accuracy, retention, and dose-response characteristics of repeated training remain unclear. Thirteen individuals (8 females and 5 males; age 22.4 ± 3.4 years; 32.6 ± 18.7 months post-ACLR) completed 18 gait biofeedback sessions over 6 weeks. Participants completed rehabilitation and exhibited involved limb first peak vGRF ≤1.12 body weight (BW) during baseline assessment of treadmill walking. Bilateral, step-by-step visual biofeedback targeted a first peak vGRF of 1.15 BW. Feedback was continuous during sessions 1-10 and was partially tapered thereafter. Outcomes included first peak vGRF target accuracy, defined as the percentage of steps within ±1% of the 1.15 BW target, first peak vGRF during retention, and the estimated training dose required to achieve target loading. First peak vGRF target accuracy increased in both limbs from ∼13% during session 1 and plateaued by session 12 (20-25%). Retention testing of the involved limb showed significantly higher first peak vGRF than baseline beginning at session 3, with these improvements maintained through session 18. The median effective dose to achieve target loading was 5 sessions (95% confidence interval: 3-14 sessions). Bilateral first peak vGRF target accuracy improved across training, while involved-limb improvements were retained before completing the 18-session protocol. These findings support the feasibility of shorter gait biofeedback regimens and provide clinically relevant dosing parameters to inform future clinical trials. gov: NCT05848622.
-
7. Comparative study of turbulence models for hemolysis prediction and hydraulic performance in centrifugal blood pumps.
7. 离心式血泵中用于溶血预测的湍流模型及水力性能对比研究PMID:日期:2026-09-19Accurate prediction of hydraulic performance and hemolysis in centrifugal blood pumps is essential for improving efficiency and reducing blood damage. Computational fluid dynamics (CFD) predictions are highly sensitive to turbulence modeling, yet systematic validation for complex rotating blood flows remains limited. Four turbulence models: RNG k-ε, k-ω SST, RSM-ω, and IDDES were evaluated for predicting hydraulic performance and hemolysis in the FDA benchmark centrifugal blood pump. Predicted pressure head and velocity fields were compared with experimental data. Hemolysis was quantified using plasma-free hemoglobin measurements at two operating conditions: 2500 RPM at 2.5 L·min and 3500 RPM at 6 L·min. RANS models (k-ω SST and RNG k-ε) showed strong agreement with experimental pressure head data, with errors of 1.1-4.7%. All models predicted hemolysis within the experimental uncertainty, with accuracy depending on operating condition. RSM-ω and k-ω SST performed better at 2500 RPM, whereas RNG k-ε and IDDES showed improved agreement at 3500 RPM. Scale-resolving models captured high-shear regions and vortex structures associated with blood damage more effectively. Turbulence model choice strongly influences hemolysis prediction. While RANS models reliably predict hydraulic performance, scale-resolving approaches better represent flow features relevant to hemolysis, particularly at higher rotational speeds.
-
8. Pectoralis major stiffness and stretch response in breast cancer survivors after breast conserving surgery and radiation therapy.
PMID:日期:2026-09-19Breast cancer survivors frequently experience shoulder dysfunction following radiation therapy, which may be related to a stiffer pectoralis major. However, intrinsic muscle stiffness at slack length and the stretch response across the shoulder abduction range of motion remain unknown. We recruited 20 female breast cancer survivors treated with breast-conserving surgery, sentinel node biopsy and radiation therapy 12-60 months prior, alongside 19 cancer-free controls. The sternocostal region of the pectoralis major was imaged using ultrasound shear wave elastography. Shear wave velocities were extracted from the images as measure of muscle stiffness throughout passive shoulder abduction. We determined slack stiffness, slack angle, and elasticity coefficient from the relationship between shear wave velocities and shoulder abduction joint angle. Slack stiffness was significantly greater in breast cancer survivors compared to controls (p = 0.029), indicating increased intrinsic muscle stiffness. Muscle stiffness remained significantly elevated throughout the entire shoulder abduction range of motion in breast cancer survivors (p < 0.001). However, slack angle (p = 0.917) and elasticity coefficient (p = 0.801) did not differ between groups, suggesting preserved functional lengthening capacity. This study provides the first evidence of increased intrinsic pectoralis major stiffness following breast-conserving surgery and radiation therapy. Despite elevated stiffness at slack length and during lengthening, the muscle's mechanical behaviour during stretch appears preserved. These findings may help explain shoulder dysfunction in breast cancer survivors and support future monitoring strategies.
-
9. Methods for the identification of ankle joint dynamics using a novel sub-malleolar interface.
9. 使用新型踝下界面的踝关节动力学识别方法PMID:日期:2026-09-19Accurate characterization of dynamic joint stiffness (DJS) is essential for understanding human locomotion and clinical pathologies. However, traditional interfaces for ankle system identification, such as custom fiberglass boots, are limited by fabrication complexity, participant discomfort, and potential mechanical issues that degrade signal fidelity. To address these bottlenecks, we developed a 3D-printed, adjustable Sub-Malleolar Interface (SMI) designed to improve mechanical coupling and experimental efficiency. We validated the SMI against a participant-specific fiberglass legacy boot in a proof-of-concept study involving one healthy participant. Three experimental paradigms were employed: (1) estimation of ankle-foot moment of inertia, (2) identification of relaxed intrinsic and reflex stiffness, and (3) identification of stiffness during 15% maximal voluntary contraction. A parallel-cascade system identification approach was used to decouple intrinsic and reflex contributions to DJS based on torque responses to position perturbations. The SMI provided reliable kinematic and kinetic data. In the relaxed condition, stiffness models achieved high goodness-of-fit (variance-accounted-for ∼91-94%); under tonic contraction, total-torque VAF remained high at most positions but fell below 90% at some angles for both interfaces. Parameter estimates closely matched the legacy boot across all paradigms. Notably, the SMI's improved mechanical coupling was associated with higher-fidelity capture of reflex-mediated torques compared with the legacy boot, which may have attenuated these signals through mechanical compliance. The newly developed sub-malleolar interface functions as a robust, reusable interface for neuromechanical system identification. By providing high-fidelity torque transmission while reducing setup time from hours to minutes, this interface offers a scalable, comfortable alternative to traditional interfaces. This advancement supports more accurate characterization of ankle dynamics and facilitates the translation of system identification methods into broader clinical research settings.
-
10. Rotator cuff arthropathy impairs shoulder mobility and drives compensatory spine and pelvic motion during overhead task.
10. 肩袖关节病会损害肩部活动能力，并在过顶任务中驱动脊柱和骨盆的代偿性运动PMID:日期:2026-09-15Rotator cuff arthropathy is associated with progressive shoulder dysfunction and pain, leading to impaired performance of activities of daily living. While loss of glenohumeral motion is well recognized, the extent to which patients adopt whole-body compensatory strategies during functional overhead tasks remains incompletely defined. Quantifying these compensatory strategies may improve functional assessment and identify secondary biomechanical adaptations that contribute to disability. Sixty-two patients with unilateral rotator cuff arthropathy performed a standardized overhead reach task using both the symptomatic and contralateral asymptomatic shoulders. Three-dimensional motion capture was used to quantify shoulder kinematics as well as cervical spine, lumbar spine, and pelvic motion throughout task execution. Peak joint angles were compared between sides to characterize motion deficits and compensatory strategies. Compared with the asymptomatic shoulder, rotator cuff arthropathy shoulders demonstrated significant reductions in flexion (57.4° vs 120.4°), abduction (28.7° vs 44.9°), and internal rotation (33.5° vs 61.7°) (all p < 0.001). Use of the symptomatic shoulder was associated with increased cervical spine extension, reflected by reduced flexion (19.1° vs 32.5°, p < 0.001), and decreased lateral bending (9.2° vs 14.6°, p < 0.001). Lumbar spine kinematics demonstrated greater axial rotation (24.0° vs 18.6°, p < 0.001) and increased extension (-4.0° vs -5.2°, p < 0.001). Pelvic motion also increased, with greater contralateral rotation observed during symptomatic shoulder use (-7.7° vs -3.3°, p < 0.001). Rotator cuff arthropathy results in profound reductions in shoulder mobility during functional overhead reaching, accompanied by systematic compensatory increases in cervical spine, lumbar spine, and pelvic motion. These altered whole-body kinematic strategies likely redistribute mechanical demands to the axial skeleton and may predispose patients to secondary spine or pelvic pathology. Recognition of these compensations has important implications for surgical decision-making, postoperative expectations, and the design of targeted rehabilitation strategies aimed at restoring function while minimizing compensatory loading.