LARYNGOSCOPE喉镜
LARYNGOSCOPE(英文缩写 LARYNGOSCOPE),ISSN 0023-852X,eISSN 1531-4995,中文译名:喉镜 是一本学术期刊。本页汇总该期刊的最新影响因子、分区信息以及最新收录于 PubMed 的文献,帮助您快速了解期刊全貌。
发文量统计区间：2025-11-01 至 2026-10-31，按本站收录文献的发表日期统计。
期刊介绍
历年影响因子趋势
| JCR 数据年份 | 影响因子 | JCR 分区 |
|---|---|---|
| 2021 | 2.970 | Q2 |
| 2022 | 2.600 | Q2 |
| 2023 | 2.200 | Q1 |
| 2024 | 2.000 | Q2 |
| 2025 | 2.000 | Q2 |
LARYNGOSCOPE 最新收录文献
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1. Pretreatment Health-Related Quality of Life and Survival in Head and Neck Cancer: A Meta-Analysis.
1. 头颈癌治疗前健康相关生活质量与生存率：一项荟萃分析PMID:日期:2026-10-04To quantify associations between pretreatment patient-reported health-related quality of life (HRQoL) domains and overall survival in head and neck cancer. PubMed, Embase, and Web of Science were searched from inception through July 27, 2026. Longitudinal studies evaluating validated patient-reported HRQoL as a prognostic exposure were included. Adjusted hazard ratios (HRs) for overall survival were harmonized to a 10-point worsening and pooled by domain using restricted maximum-likelihood random-effects models. Risk of bias, multiplicity, leave-one-out stability, cohort overlap, residual-confounding sensitivity, and reporting completeness were evaluated. Thirty-two independent studies in 40 publications were included; 43 estimates contributed to meta-analyses of 10 domains. Worse Global QoL (HR, 1.11; 95% CI, 1.08-1.14), physical functioning (1.16; 1.13-1.20), role functioning (1.09; 1.07-1.11), and social functioning (1.09; 1.06-1.12) were consistently associated with higher mortality and remained leave-one-out stable. Swallowing was associated with mortality (1.15; 1.02-1.29) but was sensitive to one study. Dyspnea was associated with higher mortality in the primary analysis (4 studies; HR, 1.16; 95% CI, 1.01-1.33), but the estimate was heterogeneous and unstable. Pretreatment HRQoL provides multidimensional prognostic information, with Global QoL and physical, role, emotional, and social functioning showing the most consistent evidence. These domains may help prioritize pretreatment supportive-care assessment, whereas sensitivity-limited or very-low-certainty findings require further confirmation and should not be interpreted as actionable treatment targets. N/A. PROSPERO number: CRD420261461389.
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2. Surgical Indications for Type II Thyroplasty in Adductor Spasmodic Dysphonia: A Scoping Review.
PMID:日期:2026-10-04This scoping review mapped evidence on surgical eligibility criteria, efficacy, durability, and safety of Type II thyroplasty with titanium bridges for adductor spasmodic dysphonia to identify gaps and inconsistencies among studies and propose preliminary international surgical indication criteria and a core outcome set for future validation. PubMed/MEDLINE and Cochrane Library were searched from inception to January 5, 2026. Two independent reviewers evaluated full-text articles based on eligibility criteria. Risk of bias was assessed using ROBINS-I V2. Overall, 32 studies were identified and 15 met the inclusion criteria. Surgical indications were heterogeneous, including patients with inadequate response to botulinum toxin injection and those who responded well but sought a permanent alternative to repeated injections. Mean Voice Handicap Index-10 scores improved from 26.3-30.4 preoperatively to 4.1-14.0 postoperatively, with sustained improvement up to 8.4 years. Perceptual, acoustic, and aerodynamic parameters significantly improved postoperatively. Revision rates ranged from 2% to 7%, and complications were minor and transient. Titanium bridge fractures were not consistently associated with symptom recurrence. Type II thyroplasty with titanium bridges provides durable and clinically meaningful voice outcomes in adductor spasmodic dysphonia, with low revision rates and acceptable safety. The evidence supports a preliminary framework for surgical eligibility based on standardized diagnosis, symptom chronicity, prior conservative therapy, and exclusion of other voice disorders. Development and validation of international surgical indication criteria and a core outcome set are necessary to support comparability and global implementation. N/A.
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3. Normal Pregnancy and Voice: A PRISMA-ScR Scoping Review of Laryngeal and Vocal Outcomes.
PMID:日期:2026-10-02Pregnancy produces physiologic adaptations that may affect laryngeal tissues, respiratory support for phonation, and voice quality. We performed a scoping review exploring the influence of pregnancy on voice and laryngeal outcomes. PubMed, CINAHL, and Web of Science. A scoping review was conducted per PRISMA-ScR guidelines. Searches of PubMed, CINAHL, and Web of Science yielded 1350 studies screened in Covidence by two reviewers. Of 107 full texts reviewed, 22 met inclusion criteria. We included human studies in which pregnancy was the primary exposure and voice-related outcomes were measured. Pregnancy-specific animal studies were included when modeling mechanisms of laryngeal change. Twenty-two studies met inclusion criteria and were grouped into domains: acoustic/aerodynamic (n = 16), patient-reported/perceptual (n = 12), physiologic laryngeal (n = 5), mechanistic animal studies (n = 4), singing voice (n = 4), and respiratory (n = 1); several studies contributed to multiple domains. Acoustic measures (fundamental frequency, jitter, shimmer) were generally unchanged, while multiple studies reported reduced maximum phonation time (MPT) during pregnancy. Subjective voice measures tended to worsen, and singer studies reported reduced vocal range and timbre changes. Physiologic studies noted increased vocal fold edema and reduced motility, most prominent in the third trimester. Mechanistic models supported hormone-associated mucosal changes and altered laryngeal protein expression. The literature on voice changes during pregnancy is limited and heterogeneous, with evidence concentrated in late pregnancy. Pregnancy is more consistently associated with reduced phonatory efficiency and worse perceived voice function than with major acoustic vocal changes. N/A.
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4. Structured Histopathology Distinguishes AFRS From eCRSwNP.
PMID:日期:2026-10-01Allergic fungal rhinosinusitis (AFRS) and eosinophilic chronic rhinosinusitis with nasal polyps (eCRSwNP) overlap clinically. Whether they represent distinct entities or points on the same spectrum is debated, and structured histopathology data from the Middle East are limited. The aim of this study was to compare clinical, radiographic, laboratory, and 13-variable structured histopathological (SHP) profiles between AFRS and eCRSwNP in a Saudi tertiary-care cohort. We retrospectively reviewed 415 adults who underwent functional endoscopic sinus surgery (FESS) at a Saudi tertiary referral center between January 2017 and January 2024. AFRS was defined by Bent and Kuhn criteria, and eCRSwNP by EPOS 2020 criteria plus 10 or more tissue eosinophils per high-power field. We compared 13-variable structured histopathology, clinical, radiographic, and laboratory features. Fifty patients (12.0%) met AFRS criteria. AFRS patients were younger (median 27 vs. 38 years; p < 0.001), had higher total serum IgE (869 vs. 191 IU/mL; p < 0.001), and more often had unilateral disease on CT (58.0% vs. 19.6%; OR 5.66, 95% CI 3.05-10.51). AFRS showed less neutrophilic infiltration, less subepithelial oedema, less hyperplastic or papillary change, and less squamous metaplasia. Recurrence was similar between groups (40.9% vs. 42.6%; p = 0.872). AFRS and eCRSwNP differ across clinical, radiographic, laboratory, and SHP domains in this Saudi cohort, supporting AFRS as a distinct phenotype within the CRSwNP spectrum. LEVEL OF EVIDENCE: 3
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5. Outcomes of Osseous Microvascular Midface Reconstruction: Does Union Matter?
5. 骨性微血管面中部重建的结局：愈合是否重要？PMID:日期:2026-10-01To assess rates of bony union and their correlation with postoperative complications following osseous orbitomaxillary microvascular reconstruction. A retrospective review was performed of patients who underwent orbitozygomaticomaxillary reconstruction with composite osseous free flaps at an academic medical center from 2011 to 2024. Demographics, intraoperative variables, and postoperative outcomes were collected. Univariable and multivariable regression analyses were conducted to evaluate factors associated with bony union. Fifty-nine patients were identified, with a mean follow-up of 3.53 years. Most subjects underwent maxillary reconstruction following oncologic resection (72.9%). The predominant flap used was the fibula free flap (78.0%), followed by the osteocutaneous radial forearm flap (16.9%). Complication rates included hardware extrusion (25.4%), fistula formation (40.7%), and bone exposure (15.3%). The rate of complete bony union was 50.0%, with partial and nonunion rates of 13.3% and 37.7%, respectively. Nonunion was more likely among patients with fistula formation (OR 4.29, p = 0.038) and those who underwent subsequent free flap (OR 8.46, p = 0.008). Multivariable regression found nonunion was associated with increasing number of sites of possible osteosynthesis (OR 36.8, p = 0.007), use of Virtual Surgical Planning (VSP) (OR 100.5, p = 0.045), and postoperative radiation therapy (OR 13.8, p = 0.032). Age, ASA class, surgeon, flap type, use of locking versus non-locking plates, ischemia time, and time from surgery to CT were not associated with nonunion. Nonunion occurred in approximately one third of cases and was associated with increasing sites of possible osteosynthesis, use of VSP, adjuvant radiation, fistula formation, and subsequent free flap. LEVEL OF EVIDENCE: 4
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6. Core Needle Biopsy in the Diagnosis of Major Salivary Gland Tumors.
6. 核心针穿刺活检在主要唾液腺肿瘤诊断中的应用PMID:日期:2026-10-01Despite increasing use of core needle biopsy (CNB) for salivary gland lesions, its clinical utility requires further evaluation. As previous studies have focused mainly on surgically confirmed lesions, this study evaluated the diagnostic utility and reliability of CNB for major salivary gland lesions irrespective of treatment modality. This retrospective cohort study included 217 patients who underwent major salivary gland CNB at the Helsinki University Hospital (HUS, Helsinki, Finland) between 2020 and 2022. Patients were classified into surgical and follow-up groups, with follow-up data review of patient records for non-operated patients through the end of 2024. Altogether, 247 CNB samples were obtained from 221 major salivary gland lesions. Ninety-three patients (42%) underwent surgery, and 128 tumors in 124 patients (58%) were followed up only. Based on histologically verified cases, CNB demonstrated 93.8% sensitivity and 98.5% specificity for malignancy, with one false benign and one false malignant result. No malignancies were identified in the follow-up group during a minimum of 2-year follow-up. CNB is a highly accurate diagnostic tool for salivary gland tumors and may facilitate the identification of lesions that can be safely managed without surgery. LEVEL OF EVIDENCE: 3
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7. Correction to "EPIDERM Technique: Safety and Outcomes of Skin Grafted Free Flaps in Head and Neck Reconstruction".
7. 对“EPIDERM技术：皮肤移植游离皮瓣在头颈部重建中的安全性和结果”的更正PMID:日期:2026-10-01该文献暂无摘要。
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8. Impact of Tranexamic Acid on Head and Neck Free Flap Outcomes: A Retrospective Cohort Analysis.
8. 氨甲环酸对头颈部游离皮瓣结局的影响：一项回顾性队列分析PMID:日期:2026-10-01Tranexamic acid (TXA) is an antifibrinolytic agent studied for its role in reducing perioperative bleeding. While it has shown promise in operations requiring free tissue transfer in plastic surgery, its application in head and neck free flap reconstruction is less documented. This study evaluates the impact of TXA on head and neck free flap surgery outcomes. This was a single-institution retrospective cohort study of adult patients who underwent head and neck reconstruction with autologous free tissue transfer between May 2023 and October 2024. Multivariable logistic regression and linear regression were used to evaluate differences between groups. Odds ratios and 95% confidence intervals were used to describe associations. A total of 215 patients were included (15.3% receiving TXA). Patients who received TXA had a higher rate of intraoperative transfusions (p = 0.049). This difference was not observed after adjustment for other factors (p = 0.21). Patients who received TXA had a more stable hemoglobin at Postoperative Day (POD) 1 (-1.84 ± 1.62 vs. -2.77 ± 1.36 g/dL, p = 0.045), however, this difference resolved by POD 7 with no difference in postoperative transfusion rates (p = 0.22). There was no difference in postoperative recipient site, donor site, or medical complications between groups. Head and neck free flap patients that received TXA had no significant difference in flap outcomes or major thrombotic events. Our results suggest that TXA is a safe option among patients undergoing free tissue transfer for head and neck reconstruction. Further prospective research with larger cohort sizes is needed to elucidate potential benefits. LEVEL OF EVIDENCE: 3
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9. Lakehouse-Driven Surgical Databases: Scoping Review and Implementation of a Free Flap Database.
9. 湖仓驱动的外科数据库：范围综述与游离皮瓣数据库的实施PMID:日期:2026-09-30To review the landscape of cloud-native analytics platforms and large language models (LLMs) applied to surgical outcomes research; to present the development of an automated head and neck free flap outcomes database as a reference implementation for using lakehouse architectures in the development of clinical databases. PubMed and Embase from January 2018 through June 2026. A scoping review of PubMed and Embase was conducted using five searches combining data architecture (e.g., "data lakehouse," "cloud-native"), clinical text extraction ("natural language processing," "LLM") surgical outcomes ("postoperative," "surgical outcome"), and domain-specific databases ("free flap," "microvascular reconstruction," "automated"). Studies were reviewed if they described database development incorporating automated outcomes classification. Of 311 studies identified, five studies included elements of incremental processing, pattern-matching-gated LLM classification, or fault-tolerant parallel processing for prospective database maintenance. No implementation examples combined all architectural characteristics. We present the development of a production database for microvascular surgery that automatically identifies free flap cases, collects and analyzes operative notes, validates cohort membership through LLM reasoning, and classifies outcomes across multiple dimensions (flap type, indication, flap failure, hardware complications, bony complications, etc.), all operating incrementally as new cases enter the electronic health record and existing cases are updated. We describe what appears to be the first data lakehouse-based automated surgical database applied to otolaryngology, detail architectural decisions required for production, and identify critical unresolved challenges including LLM validation standards, data access barriers, and the translation of clinical domain expertise into computational logic. N/A.
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10. Cochlear Implants for Radiation-Induced Hearing Loss in Nasopharyngeal Cancer: A Systematic Review.
PMID:日期:2026-09-29To evaluate the safety and efficacy of cochlear implantation for auditory rehabilitation in patients with nasopharyngeal carcinoma (NPC) after radiation. CINAHL, Cochrane Library, PubMed, and Scopus were searched from inception through February 2026. Studies reporting cochlear implantation for hearing loss after radiation for NPC were included. Subjective and objective measures of hearing, including thresholds, speech perception, quality-of-life outcomes, and surgical complications, were extracted. Pooled means and proportions with 95% confidence intervals (CI) were calculated for available outcomes using random-effects models. Study quality and risk of bias were assessed using Oxford Levels of Evidence and Joanna Briggs Institute critical appraisal tools. Twelve studies (N = 69 ears) were included. Cochlear implantation was most commonly performed via standard mastoidectomy with posterior tympanotomy, with alternative approaches used selectively. Surgical and device-related complications were uncommon, with 80.4% (95% CI: 55.1-96.7) without intraoperative complications and 96.5% (95% CI: 88.3-99.5) without postoperative complications. Audiometric improvement was observed in 91.3% of patients (95% CI: 73.1-98.8), with gains in speech perception and patient-reported outcomes. Mean duration of profound hearing loss prior to implantation was 6.5 years. Cochlear implantation after radiation in patients with NPC is generally safe and effective, providing meaningful auditory and functional benefits even in long-standing hearing loss. These findings support routine audiologic surveillance after radiation to enable timely referrals for rehabilitation. NA.