TRENDS IN PARASITOLOGY寄生虫学趋势
TRENDS IN PARASITOLOGY(英文缩写 TRENDS PARASITOL),ISSN 1471-4922,eISSN 1471-5007,中文译名:寄生虫学趋势 是一本学术期刊。本页汇总该期刊的最新影响因子、分区信息以及最新收录于 PubMed 的文献,帮助您快速了解期刊全貌。
发文量统计区间:2025-09-27 至 2026-09-27,按本站收录文献的发表日期统计。
期刊介绍
历年影响因子趋势
| JCR 数据年份 | 影响因子 | JCR 分区 |
|---|---|---|
| 2021 | 10.528 | Q1 |
| 2022 | 9.600 | Q1 |
| 2023 | 7.000 | Q1 |
| 2024 | 6.600 | Q1 |
| 2025 | 7.600 | Q1 |
TRENDS IN PARASITOLOGY 最新收录文献
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1. Sailing to a deeper understanding of malaria parasite invasion.
PMID:日期:2026-09-23In a recent article by Haile et al., the atomic-level structure of the protein complex responsible for the invasion of the malaria parasite into red blood cells is described. Here, the key findings and the implications for the development of next-generation antimalarials are reviewed.
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2. No single magic bullet: the case for combined interventions for global malaria elimination and eradication.
PMID:日期:2026-09-17The past 6 decades have witnessed steady progress in malaria control, resulting in marked reductions in disease burden across many endemic regions. However, the pace of malaria elimination has remained slow, hindered by numerous biological, clinical, and epidemiological challenges. Innovative integrated approaches are required for a sustainable response to this persistent global health threat. Because malaria transmission and parasite biology are complex, combining antimalarial drugs, vector control measures, and vaccines offers the best chance of achieving long-term malaria elimination. This review examines emerging malaria control and elimination tools, including next-generation insecticides, novel antimalarial drug classes, and mRNA-based vaccines. We discuss how they can be strategically integrated to enhance intervention effectiveness, interrupt transmission, and accelerate progress toward malaria elimination and eradication.
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4. What's in a name? Discovering Leishmania.
PMID:日期:2026-09-032 June 2026 marked the centenary of the death of Sir William Boog Leishman, the Scottish physician after whom Leishmania was named. However, he was not the first to describe the parasite. In this article, we recount this discovery and explain the etymological conventions that ensured Leishman's name was preserved in scientific history.
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5. New insights on Plasmodium gene expression from direct RNA sequencing.
PMID:日期:2026-09-03Oxford Nanopore Technology (ONT) direct RNA sequencing enables the sequencing of native RNA molecules without cDNA conversion. The long-read approach captures full-length reads spanning entire genes and has transformed the study of gene expression in Plasmodium parasites by enabling analysis of untranslated regions, isoforms, and alternative splicing. In addition, ONT provides unique insights into non-coding RNAs, RNA modifications, and polyadenylated tail dynamics, which are expanding our understanding of post-transcriptional regulation in Plasmodium, including processes beyond translational repression in gametocytes and sporozoites. Here, we discuss the past and future applications of direct RNA sequencing in Plasmodium research and highlight its advantages, limitations, and future prospects.
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6. Equitable access to monoclonal antibodies targeting parasites.
PMID:日期:2026-09-01Monoclonal antibodies (mAbs) have reshaped prevention and treatment of infectious diseases. However, the development of mAbs against parasitic diseases that disproportionately impact populations in resource-limited settings has received lower priority. Recent trials in Africa show that long-acting mAbs can prevent Plasmodium falciparum infection in children and adults. Early studies suggest that mAb pharmacokinetics differ between malaria-endemic and nonendemic populations, with age and prior parasite exposure possibly affecting the minimum amount of mAb required for durable protection. We present evidence that antiparasitic mAb studies should account for fragment crystallizable receptor polymorphisms and host factors commonly found in endemic populations. We discuss economic and manufacturing barriers to accessing mAbs in resource-limited settings, which have implications for the future use of these promising interventions.
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7. Beyond detoxification: xenobiotic-metabolizing enzymes rewire mosquito sensory perception.
PMID:日期:2026-09-01Mosquito olfaction regulates host-seeking, ecological adaptation, and vectorial capacity. Beyond the classical receptor-centric paradigm, we argue that xenobiotic-metabolizing enzymes form a dynamic perireceptor layer that actively sculpts odor identity, signal intensity, and duration. This metabolism gain control mechanism may integrate olfactory sensitivity and behavioral plasticity within a unified sensory framework.
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8. Complement C1q-binding protein at the host-protozoan interface: knowns and unknowns.
PMID:日期:2026-09-01Complement C1q-binding protein (C1QBP) is exploited by protozoan parasites. In this forum, we summarize direct evidence for C1QBP as an adhesion receptor (Plasmodium) and an immune subversion target (Toxoplasma), highlight gaps, and propose research priorities to define C1QBP as a multifunctional signaling hub at the host-parasite interface.
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9. More than just a phase: the essential role of condensates in Trypanosoma brucei survival.
PMID:日期:2026-08-31The study of biomolecular condensates and other membraneless organelles has shifted the paradigm of cellular organisation, yet their role in parasitic biology remains an emerging field. While model eukaryotes provide the blueprint for phase separation and spatial compartmentalisation, kinetoplastid parasites offer a unique lens through which to explore the functional limits of these 'regulatory hubs'. In this opinion article, we argue that their unconventional biology renders them valuable models for understanding spatial regulation of gene expression. While Trypanosoma brucei serves as the current benchmark, significant gaps remain regarding condensate diversity across other kinetoplastids. We propose a broader investigation into whether these organisms utilise conserved condensates with divergent molecular compositions or entirely novel assemblies to drive their life cycle, pathogenesis, and immune evasion.
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10. Questing for sustainable control of cattle ticks: bottlenecks in developing efficacious vaccines.
PMID:日期:2026-08-31Naturally acquired immunity against cattle ticks, observed in certain breeds of cattle, indicates that development of vaccines to prevent infestations is feasible. This opinion article focuses on the knowledge needed to guide their development, formulation, and testing. It discusses the limitations of current experimental vaccines and tests used to evaluate them and points to the research needed to achieve a truly efficacious vaccine. It includes using better strategies to select antigens, not relying solely on indirect readouts of efficacy but rather elucidating the immune mechanisms responsible for reducing tick loads and overcoming the low coverage of the host's major histocompatibility complex class II molecules, as well as avoiding confounding factors in designs for testing vaccines and considering management practices that impact efficacy.