CLINICAL MICROBIOLOGY AND INFECTION临床微生物学与感染
CLINICAL MICROBIOLOGY AND INFECTION(英文缩写 CLIN MICROBIOL INFEC),ISSN 1198-743X,eISSN 1469-0691,中文译名:临床微生物学与感染 是一本学术期刊。本页汇总该期刊的最新影响因子、分区信息以及最新收录于 PubMed 的文献,帮助您快速了解期刊全貌。
发文量统计区间：2025-09-27 至 2026-09-27，按本站收录文献的发表日期统计。
期刊介绍
历年影响因子趋势
| JCR 数据年份 | 影响因子 | JCR 分区 |
|---|---|---|
| 2021 | 13.310 | Q1 |
| 2022 | 14.200 | Q1 |
| 2023 | 10.900 | Q1 |
| 2024 | 8.500 | Q1 |
| 2025 | 8.700 | Q1 |
CLINICAL MICROBIOLOGY AND INFECTION 最新收录文献
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1. Hantavirus risk and preparedness in Europe in an era of climate change and global mobility.
PMID:期刊:日期:2026-10-01Hantaviruses are rodent-borne zoonoses causing haemorrhagic fever with renal syndrome and hantavirus cardiopulmonary syndrome. In Europe, Puumala virus (PUUV) and Dobrava virus (DOBV) account for most recognized disease; Seoul virus (SEOV) is relevant to ports and urban settings. The 2026 MV Hondius cruise-ship cluster of Andes hantavirus (ANDV) infections, involving passengers from 23 countries, has highlighted urgent gaps in European preparedness for both endemic and imported hantavirus disease. To review hantavirus epidemiology, ecology, clinical recognition, diagnostics, and preparedness in Europe, with emphasis on endemic PUUV, DOBV, and SEOV, and to clarify the separate relevance of imported ANDV infection for travel medicine and maritime response. We conducted a structured narrative review of literature published from January 2000 to May 2026, prioritizing surveillance reports, systematic and narrative reviews, rodent ecology studies, diagnostic evaluations, external quality assessment studies, and outbreak investigations. WHO, European Centre for Disease Prevention and Control, and International Health Regulations guidance documents were also reviewed. European hantavirus epidemiology is heterogeneous and shaped by reservoir ecology, biome-specific rodent dynamics, clinical awareness, diagnostic capacity, and surveillance practice. Climate effects are indirect and regionally variable, mediated by mast years, predator-prey dynamics, winter conditions, land use, reservoir density, and human exposure. Diagnostic preparedness is uneven, particularly for molecular detection. Imported ANDV infection is rare in Europe but relevant to travel medicine and high-consequence preparedness because it can cause severe hantavirus cardiopulmonary syndrome and, unlike endemic European hantaviruses, has documented person-to-person transmission. European preparedness should prioritize PUUV, DOBV, and SEOV through rodent biomonitoring, harmonized surveillance, improved molecular diagnostics, and locally calibrated early warning.
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2. Real-world influenza surveillance and vaccine effectiveness in children: a multicentre study of the Italian Federation of Primary Care Paediatricians.
PMID:期刊:日期:2026-10-01Influenza is a significant cause of morbidity among children and a significant factor in primary care consultations. Although numerous studies on influenza vaccine effectiveness (VE) have been conducted, the majority of the available data comes from hospital settings; the objective of this study is to estimate influenza VE in children in paediatric primary care settings. A multicentre observational study was conducted among family paediatricians working in outpatient clinics in various Italian regions during the 2024/2025 influenza season. Children aged 2-6 years with influenza-like illness (ILI) were enrolled and underwent rapid antigen point-of-care tests (POCT). Children who were positive on POCT underwent molecular RT-PCR tests for influenza in a centralized laboratory. VE was estimated as 1 - OR by a test-negative case-control design and as 1 - incidence rate ratio by a cohort study, in which the aggregated denominator of the children included in the beneficiary lists of the participant paediatricians was used to compute the incidence in vaccinated and nonvaccinated. The circulation of influenza was characterized by a clear seasonal pattern, with sustained activity of the virus throughout the period. Seven hundred thirty-nine ILI cases were tested. The results showed a 79% (95% CI: 70-86) reduction of laboratory-confirmed influenza ILI, i.e. vaccine efficacy (1 - OR). The results were consistent when sensitivity analysis was performed for different types of influenza vaccine and when results obtained by POCT were compared with results obtained by RT-PCR confirmation. When the results were assessed by the cohort method, vaccination was associated with a marked reduction in incidence of influenza with VE 76% (1 - incidence rate ratio); 95% CI: 67-82) and no reduction of ILI that tested negative for influenza virus. This study shows high VE of the 24-25 influenza vaccines against symptomatic disease in healthy children, demonstrating the feasibility to perform influenza surveillance in a paediatric primary care setting in real-life conditions.
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3. Reporting of antibiotic resistance in randomized controlled trials of new antibiotics: a systematic review.
PMID:期刊:日期:2026-10-01Planning and reporting of antibiotic resistance at baseline and as an outcome in randomized controlled trials (RCTs) of new antibiotics is important for trial interpretation. To assess the planning and reporting of antibiotic susceptibility testing (AST) in recent RCTs of new antibiotics. Data sources: MEDLINE, EMBASE, Web of Science, Cochrane Central, and Ai2 Paper Finder were searched from January 2017 to July 2025, with no language restrictions; complemented by backward and forward citation screening for secondary publications and registry results, and the WHO antibacterial pipeline. RCTs of new antibiotics listed in Phase 2/3 of the 2025 WHO antibacterial pipeline. Adults and children with bacterial infections. New antibiotics vs. any comparator. Cochrane Risk of Bias 2. Four prespecified resistance domains were extracted-real-time AST, central-laboratory baseline AST, AST-stratified primary efficacy outcome assessment, and assessment of resistance acquisition during follow-up. We calculated proportions of trials and arms with planning and reporting of each domain. Fifty-seven RCTs evaluating 23 new antibiotics across 119 arms were included. Real-time baseline AST was reported in 17 of 57 (29.8%) trials, including 6 of 62 (9.7%) intervention and 17 of 57 (29.8%) comparator arms. Central-laboratory baseline AST was reported in 48 of 57 (84.2%). The primary efficacy outcome was stratified by baseline AST in 36 of 48 (75%) with available baseline AST data. Resistance acquisition was reported in 22 of 57 (38.6%) based on clinical infections; none of the trials conducted surveillance for resistance development. Only 2 of 57 trials planned to assess all four resistance domains, and only 9 of 57 reported results for all four domains. In RCTs of antibiotics approved or in late-stage development since 2017, resistance assessment remained inconsistently planned and reported. Future trials should provide local laboratories with real-time AST tools, prespecify resistance-stratified analyses, and assess resistance acquisition through routine surveillance samples.
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5. Antimicrobial resistance should be a core outcome in antimicrobial randomized controlled trials.
PMID:期刊:日期:2026-10-01该文献暂无摘要。
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7. Andes virus at rural-urban interfaces: avoiding alarm while broadening One Health surveillance.
PMID:期刊:日期:2026-10-01该文献暂无摘要。
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8. The ESCMID framework for reaching consensus in clinical guidelines.
PMID:期刊:日期:2026-10-01As the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) continues to expand its guidelines programme, further methodological standardization is needed. This project aimed to develop a framework for standardizing consensus methods in ESCMID guideline panels. Two scoping reviews were conducted to inform the framework: (i) a PubMed review to identify and map formal consensus methods used in guideline development, and (ii) a review of methodological guidance documents from national and international guideline-developing organizations to examine how consensus is operationalized in practice. Findings were synthesized using descriptive analyses and narrative synthesis and were integrated with ESCMID's methodological approach and feasibility considerations. The draft framework underwent stakeholder review and was revised accordingly before final approval by ESCMID governance bodies. ESCMID developed a standardized framework for reaching consensus in guideline panels, centred on mandatory anonymous voting when issuing recommendations, with consensus defined as ≥80% agreement among voting members. The framework defines voting rights and participation requirements, standardizes voting options and outcome reporting, and establishes procedures to manage nonresponsiveness and address lack of consensus through iterative rewording and repeat voting rounds. Oversight and documentation requirements are specified to support transparency and consistency. This framework represents an advancement in guideline development for ESCMID. It is designed to enhance quality, transparency, and consistency of ESCMID guidelines, while reducing sources of bias. Aligned with ESCMID's methodological rigour and commitment to evidence-based practice, it strengthens trustworthiness of ESCMID clinical guidelines.
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9. Antifungal prophylaxis in influenza-associated pulmonary aspergillosis: addressing persistent challenges.
PMID:期刊:日期:2026-10-01该文献暂无摘要。
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10. Potential biases in observational infectious disease studies: examples using directed acyclic graphs.
PMID:期刊:日期:2026-10-01Bias is a systematic error that threatens the (internal) validity of research. Observational studies in infectious diseases are especially prone to bias because they are typically nonrandomized and often rely on routinely collected or retrospective data. To provide an overview of common biases in observational infectious diseases research, introduce the concept of directed acyclic graphs (DAGs), and outline practical approaches for bias identification and mitigation. This narrative review draws on biases commonly encountered by the authors as editors, reviewers, and clinicians, supplemented by PubMed searches and recent reviews from other medical fields. The paper introduces DAGs as a conceptual tool to identify bias. Biases are grouped into selection, time-related, and information bias. Examples from published infectious diseases studies are given together with strategies to detect and reduce bias. Intended as an introductory guide for clinicians, investigators, and reviewers, this paper aimed to improve critical appraisal and study design, while acknowledging it does not cover all possible biases.