JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH妇产科学杂志（日本）
JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH(英文缩写 J OBSTET GYNAECOL RE),ISSN 1341-8076,eISSN 1447-0756,中文译名:妇产科学杂志（日本） 是一本学术期刊。本页汇总该期刊的最新影响因子、分区信息以及最新收录于 PubMed 的文献,帮助您快速了解期刊全貌。
发文量统计区间：2025-09-27 至 2026-09-27，按本站收录文献的发表日期统计。
期刊介绍
历年影响因子趋势
| JCR 数据年份 | 影响因子 | JCR 分区 |
|---|---|---|
| 2021 | 1.697 | Q4 |
| 2022 | 1.600 | Q4 |
| 2023 | 1.600 | Q3 |
| 2024 | 1.500 | Q3 |
| 2025 | 1.700 | Q3 |
JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH 最新收录文献
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1. PD-L1 Expression in Uterine Mesenchymal Tumors: A Comparative Immunohistochemical Analysis.
PMID:日期:2026-10-01To evaluate and compare programmed cell death-ligand 1 (PD-L1) expression across benign and malignant uterine mesenchymal tumors using immunohistochemical analysis. This retrospective study included 100 patients who underwent hysterectomy for uterine mesenchymal tumors at a single tertiary center between 2000 and 2022. Cases included leiomyoma (LM; n = 20), leiomyosarcoma (LMS; n = 20), low-grade endometrial stromal sarcoma (LG-ESS; n = 20), high-grade endometrial stromal sarcoma (HG-ESS; n = 20), and endometrial stromal nodule (ESN; n = 20). Immunohistochemical staining was performed using the PD-L1 (22C3) antibody, and PD-L1 expression was evaluated using the combined positive score. Clinicopathological parameters and PD-L1 expression were compared among tumor subtypes. Patients with HG-ESS demonstrated a significantly higher mean age at diagnosis compared with the other histopathological subtypes. PD-L1 expression was detected in 9 (45%) LMS, 10 (50%) HG-ESS, 3 (15%) LG-ESS, and 1 (5%) ESN cases, whereas no LM cases demonstrated positivity. PD-L1 expression rates were significantly higher in LMS and HG-ESS than in LM, LG-ESS, and ESN cases (p < 0.0001). Combined group analyses also demonstrated significantly higher PD-L1 expression rates in the combined LMS/HG-ESS group compared with the LG-ESS group and the combined LM/ESN group (p < 0.0001). These findings demonstrate increased PD-L1 expression in aggressive uterine mesenchymal tumors; however, the clinical and therapeutic significance of these immunohistochemical findings remains unclear. Further studies integrating PD-L1 expression with clinical findings and treatment outcomes are needed to determine the potential therapeutic relevance of PD-L1 in these neoplasms.
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2. Preoperative Anxiety and Early Postoperative Recovery Among Women Undergoing Gynecologic Surgery in Vietnam: A Prospective Longitudinal Observational Study.
PMID:日期:2026-09-01To determine the prevalence of preoperative anxiety among women undergoing gynecologic surgery in Vietnam and evaluate its association with early postoperative pain, sleep disturbance, and functional status. This prospective longitudinal observational study included 394 women scheduled for gynecologic surgery at a tertiary hospital in Hanoi, Vietnam, from May to December 2024. Preoperative anxiety was assessed using the Generalized Anxiety Disorder-7 scale. Preoperative information and counseling, perceived social support, and clinical characteristics were evaluated before surgery. Pain and functional status were assessed 48 h after surgery using the Numeric Rating Scale and Barthel Index, respectively, while the Insomnia Severity Index (ISI) was administered at the same assessment using its standard 2-week recall period. Multivariable linear and logistic regression models were performed to identify factors associated with preoperative anxiety and postoperative outcomes. One hundred thirty-one participants (33.2%) screened positive for anxiety symptoms (GAD-7 ≥ 5), with mild, moderate, and severe anxiety observed in 25.6%, 4.6%, and 3.0% of the cohort, respectively. Preexisting mental health conditions, lower perceived quality of preoperative information and counseling, and lower perceived support from significant others and friends were associated with higher preoperative anxiety scores. Higher preoperative anxiety was associated with greater postoperative pain intensity and higher ISI scores, but not with early functional status. Preoperative anxiety was highly prevalent among women undergoing gynecologic surgery and was associated with poorer early postoperative pain and sleep outcomes. Routine anxiety screening, improved preoperative communication, and targeted psychosocial support may contribute to more patient-centered perioperative care.
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3. Advanced Paternal Age: Implications on Fertility, Pregnancy Outcomes, and Offspring Health.
PMID:日期:2026-09-01To review associations between advanced paternal age (APA) and male reproductive health, assisted reproductive technology (ART) outcomes, pregnancy outcomes, and offspring health, to grade the evidence in each domain, and to address counseling implications. Narrative review with a structured, reproducible search. PubMed/MEDLINE was searched from 1 January 1990 to 4 September 2026 using controlled-vocabulary and free-text terms for paternal age and for reproductive, pregnancy, perinatal, and offspring outcomes, limited to human studies in English (1975 records), supplemented by hand-searching, Cochrane reviews, and professional society guidance. Systematic reviews, randomized trials, and large cohorts were prioritized, and confidence in each association was graded qualitatively. APA (≥ 40 years) is consistently associated with lower semen volume, motility, and viability, higher sperm DNA fragmentation, and a linear increase in de novo mutations. Associations with reduced natural fecundability and modestly higher miscarriage risk are moderately consistent; ART outcomes are heterogeneous and largely attenuated once maternal age is controlled. Large registries show small but consistent associations with stillbirth, preterm birth, selected congenital anomalies, schizophrenia, and autism (relative effects mostly 1.1-3.0); associations with bipolar disorder, ADHD, childhood cancer, and cognitive outcomes are weaker or inconsistent. Because these outcomes are rare, absolute increments remain small. Paternal age alone is not an evidence-based indication for ICSI, sperm DNA fragmentation testing, preimplantation genetic testing, or other add-ons. APA is associated with measurable changes in sperm biology and modest increases in relative risk for several adverse outcomes, most evident beyond 40 years. Nearly all evidence is observational and should not be read as causal. Paternal age warrants inclusion in reproductive counseling, communicated in absolute terms and without alarm. Beyond biological risks, APA raises concerns about long-term child welfare, emotional well-being, and potential socio-economic implications due to a greater risk of early parental loss.
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4. Two-Dimensional Characterization of Maternal BMI and Height Associations With Pregnancy and Perinatal Outcomes After Frozen Embryo Transfer.
PMID:日期:2026-09-01To characterize maternal body mass index (BMI) and height as two nearly independent body-size dimensions in relation to pregnancy and perinatal outcomes after frozen-thawed embryo transfer (FET), and assess whether their joint evaluation reveals patterns not captured by BMI alone. In a single-center retrospective cohort of 10 059 FET cycles, dose-response relationships of BMI and height with 15 pregnancy-related outcomes were modeled using restricted cubic splines with modified Poisson regression and robust variance estimators. A joint additive model generated two-dimensional risk surfaces adjusted for maternal age, endometrial preparation, and obstetric covariates. BMI was significantly associated with nine of 15 outcomes and height with seven. Two-dimensional risk maps showed outcome-specific patterns: hypertensive disorders of pregnancy were predominantly BMI-associated, whereas small-for-gestational-age and gestational diabetes reflected both dimensions, with higher risks in the low-BMI/short-stature and high-BMI/short-stature regions, respectively. Exploratory subgroup analyses by endometrial preparation method suggested possible heterogeneity for cesarean section, large-for-gestational-age, and miscarriage. Joint evaluation of BMI and height revealed heterogeneous body-size risk patterns-predominantly BMI-associated, height-associated, or combined-that BMI alone does not capture. Because height is readily available before pregnancy, considering it with BMI may refine body-size risk assessment after FET.
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5. Successful Live Birth Following Micro-Stimulation IVF in a Patient With Recurrent Serous Borderline Ovarian Tumor: A Case Report.
PMID:日期:2026-09-01Fertility preservation in women with recurrent serous borderline ovarian tumors (SBOTs) remains clinically challenging because of concerns regarding oncological safety and limited evidence. We report the case of a young woman with FIGO Stage IIIA1 SBOT with lymph node involvement who experienced multiple recurrences with adverse pathological features, including micropapillary architecture and stromal microinvasion. Following multidisciplinary discussion and comprehensive counseling, a brief micro-stimulation in vitro fertilization protocol was performed for embryo cryopreservation prior to repeat fertility-sparing surgery to minimize treatment delay. After complete macroscopic disease clearance, frozen-thawed embryo transfer was carried out, resulting in a successful term live birth. No clinical or radiological evidence of recurrence was observed during the available follow-up period. This case suggests that an individualized fertility-first strategy may be considered in carefully selected patients with advanced recurrent SBOT under strict multidisciplinary evaluation and close surveillance.
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6. Mapping the Global Research Landscape of Transvaginal Natural Orifice Transluminal Endoscopic Surgery (vNOTES): Türkiye's Position, Contribution, and Collaboration Networks (2012-January 2026).
PMID:日期:2026-09-01This study evaluated Türkiye's position and contribution within the global research landscape of vaginal natural orifice transluminal endoscopic surgery (vNOTES) from 2012 to January 15, 2026. Web of Science, Scopus, and TÜBİTAK ULAKBİM TR Index searches yielded 466, 689, and 210 records, respectively (total n = 1365). After removal of 415 duplicates, 125 ineligible document types, and 353 records failing relevance or analytical eligibility criteria, 472 peer-reviewed articles and reviews were included. VOSviewer and CiteSpace were used for bibliographic coupling, coauthorship, co-citation, and temporal mapping. International country rankings and citation-based networks were calculated from the comparable Web of Science and Scopus metadata. Türkiye ranked second in publication output with 47 documents and showed high collaboration intensity (total link strength = 472). Institutional and author networks indicated a transition from isolated single-center reports toward multicenter collaboration, including the TR-MIGS platform. Thematic mapping showed expansion from feasibility studies toward high-BMI populations, emergency applications, pelvic-floor procedures, and other complex indications. Records assigned to 2026 reflect indexing only through January 15 and were treated as a partial-year research-front snapshot. Türkiye has become a prominent contributor to global vNOTES research. Its contribution is characterized by dense national collaboration and diversification toward complex clinical applications; however, bibliometric prominence should not be interpreted as direct evidence of clinical superiority.
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7. Cervical, Uterine, and Ovarian Cancers in Chinese Women Aged 55 Years and Older: Burden, Temporal Trends, Risk Attribution, and Future Projections From the Global Burden of Disease Study 2021.
PMID:日期:2026-09-01To compare the burden, temporal trends, risk factor attribution, and future projections of cervical, uterine, and ovarian cancers among Chinese women aged 55 years and older. We conducted a population-based descriptive and projection analysis using data from the Global Burden of Disease Study 2021. Incidence, mortality, disability-adjusted life years (DALYs), and corresponding age-standardized rates for cervical, uterine, and ovarian cancers were extracted for 1990-2021. Age-specific burden, temporal trends, and attributable risk factors were examined. Incidence and mortality from 2022 to 2036 were projected using a Bayesian age-specific trend model. From 1990 to 2021, the absolute numbers of incident cases, deaths, and DALYs increased for all three cancers among Chinese women aged 55 years and older, whereas age-standardized mortality and DALY rates generally declined. In 2021, cervical cancer showed the highest overall burden, with mortality rates increasing markedly in the oldest age groups. Uterine cancer showed the largest increase in incidence age-standardized rate and a burden concentrated mainly in the younger segment of older women. Ovarian cancer showed a relatively unfavorable mortality pattern and was projected to have increasing incidence and mortality through 2036. Risk attribution differed by cancer type: cervical cancer mortality was mainly attributable to unsafe sex, uterine cancer mortality to high body mass index, and ovarian cancer mortality to mixed metabolic and environmental or occupational risks. Cervical, uterine, and ovarian cancers remain substantial and heterogeneous health burdens among older Chinese women. Despite declines in age-standardized mortality and DALY rates, population aging is likely to increase the absolute burden. Age-specific prevention, screening, early detection, and resource allocation are needed for older women in China.
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8. Prognostic Impact of Serum microRNA Profiles on the Progression-Free Survival of Patients With High-Grade Serous Ovarian Cancer Receiving Neoadjuvant Chemotherapy.
PMID:日期:2026-09-01High-grade serous ovarian cancer is a deadly cancer with a poor prognosis. Serum microRNAs have been used to detect and diagnose various cancers. We aimed to investigate the prognostic impact of serum microRNA profiles pre-, peri-, and post-primary treatment on the progression-free survival of patients with advanced high-grade serous ovarian cancer receiving neoadjuvant chemotherapy. Patients were prospectively recruited, and pre-, peri-, and post-treatment blood samples were collected. MicroRNA microarray results, together with the clinical and surgical data, were analyzed using Cox regression with leave-one-out least absolute shrinkage and selection operator for progression-free survival. Overall, 29 patients were included. A combined analysis of pre-treatment serum microRNAs and clinical factors showed a higher c-index (0.86) for distinguishing high- and low-risk groups for poor progression-free survival outcomes compared to analyzing each factor alone (0.70 and 0.64, respectively). The high-risk group exhibited significantly worse progression-free survival (log-rank, p < 0.01). The serum microRNA profile at 3 months post-treatment showed outstanding discrimination (c-index of 1.00). Changes in the microRNA profile between pre- and peri-treatment had no prognostic impact; however, the difference between pre-treatment and 3 months post-treatment exhibited excellent discrimination (c-index of 1.00). In patients with advanced high-grade serous ovarian cancer who received neoadjuvant chemotherapy, a combination of the pre-treatment serum microRNA profiles and clinical factors, or the 3-month post-treatment serum microRNA profile could distinguish between those in high- and low-risk groups for poor progression-free survival outcomes.
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9. Impact of the 2016 Kumamoto Earthquake on ART Subsidy Applications in Kumamoto Prefecture: Interrupted Time-Series Analysis.
PMID:日期:2026-09-01Natural disasters may disrupt access to assisted reproductive technology (ART) services. This study evaluated the impact of the 2016 Kumamoto earthquake on ART utilization in Kumamoto Prefecture, accounting for nationwide trends and policy changes. We conducted an interrupted time-series analysis using annual ART subsidy application data in Kumamoto Prefecture from 2005 to 2020. Nationwide application counts were included as an offset to adjust for national trends related to the 2016 subsidy policy revision. Age-specific patterns were also examined using normalized indices. In analysis adjusted for nationwide trends, ART subsidy applications showed a significant immediate reduction in 2016 (incidence rate ratio [IRR] = 0.84, 95% confidence interval [CI]: 0.77-0.91), followed by a gradual recovery (IRR for slope change = 1.06, 95% CI: 1.04-1.09). The decline was more pronounced among women aged 40 years and older, whereas applications among younger women remained relatively stable. The 2016 Kumamoto earthquake was associated with a substantial decline in ART subsidy applications in Kumamoto Prefecture beyond nationwide trends. This reduction was most pronounced among women aged 40 years and older, suggesting age-related differences in responses to disaster-related disruptions.
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10. Comparison of Carotid Intima-Media Thickness and Serum Endocan Levels in Surgical and Natural Menopause With Premenopausal Women.
PMID:日期:2026-09-01Menopause is associated with increased cardiovascular risk due to estrogen depletion. This study aimed to compare carotid intima-media thickness (CIMT) and serum endocan levels in women with natural menopause, surgical menopause, and premenopausal status, and to evaluate their potential roles as biomarkers for cardiovascular risk stratification. This prospective observational study included 88 healthy women aged 45-60 years: 32 with surgical menopause, 30 with natural menopause, and 26 who were premenopausal. Serum endocan concentrations were measured using an enzyme-linked immunosorbent assay, and bilateral CIMT was assessed ultrasonographically. Between-group comparisons were performed using appropriate parametric or non-parametric tests. Multivariable linear regression analyses adjusted for age and body mass index (BMI) were performed. Serum endocan was natural-log transformed before multivariable analysis because of its skewed distribution. Serum endocan concentrations differed significantly among the three groups (overall p < 0.001), with the highest levels in surgical menopause, followed by natural menopause and premenopause. The association between menopausal group and log-transformed endocan remained significant after adjustment for age and BMI (overall p < 0.001). Overall mean CIMT did not differ significantly among the groups in either unadjusted (p = 0.913) or adjusted analyses (p = 0.703). Age, but not menopausal group or BMI, was independently associated with overall mean CIMT (p = 0.003). Serum endocan levels were independently associated with menopausal status after adjustment for age and BMI, with the highest concentrations observed in women with surgical menopause. In contrast, CIMT was not independently associated with menopausal status. These findings support further investigation of endocan as a potential marker of menopause-associated endothelial alterations. However, prospective longitudinal studies are strictly required to validate this indirect hypothesis and establish causality.