CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY加拿大生理学与药理学杂志
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY(英文缩写 CAN J PHYSIOL PHARM),ISSN 0008-4212,eISSN 1205-7541,中文译名:加拿大生理学与药理学杂志 是一本学术期刊。本页汇总该期刊的最新影响因子、分区信息以及最新收录于 PubMed 的文献,帮助您快速了解期刊全貌。
发文量统计区间：2025-09-24 至 2026-09-24，按本站收录文献的发表日期统计。
期刊介绍
历年影响因子趋势
| JCR 数据年份 | 影响因子 | JCR 分区 |
|---|---|---|
| 2021 | 2.245 | Q4 |
| 2022 | 2.100 | Q3 |
| 2023 | 1.700 | Q3 |
| 2024 | 1.300 | Q4 |
| 2025 | 1.800 | Q3 |
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY 最新收录文献
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1. Analysis of the expression of genes encoding the endothelin signaling pathway in fetal, healthy and diseased adult human heart using single-cell transcriptomics.
PMID:日期:2026-09-17This study maps the cellular landscape of the principal genes (EDN1, EDN2, EDN3, EDNRA, EDNRB, ECE1, and ECE2) in the endothelin signaling pathway using published single cell/nucleus RNA sequencing da…
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2. QT interval prolongation in the coronary intensive care unit: prevalence, associated drugs and clinical-genetic risk factors.
PMID:日期:2026-09-17We aimed to investigate the prevalence of QTc interval prolongation (QTcIP), QTc-prolonging drug exposure, and associated clinical and genetic risk factors in adult patients hospitalized in the Corona…
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3. Emerging evidence of trained immunity and inflammatory programming in atherosclerotic cardiovascular disease.
PMID:日期:2026-09-16[中文摘要] 动脉粥样硬化性心血管疾病（ASCVD）尽管在危险因素控制和降脂治疗方面取得了重大进展，但仍然是全球发病和死亡的主要原因。炎症是动脉粥样硬化的核心驱动因素，参与疾病的发生、进展和额外心血管风险。本文总结了动脉粥样硬化的病理生理学，重点阐述了斑块形成和不稳定性背后的炎症机制、抗炎治疗策略，以及固有免疫细胞的表观遗传和代谢编程在维持未消退炎症中的新兴作用。
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4. Role of aerobic exercise training on myocardial infarction induced-cardiac dysfunction, dysautonomia and oxidative stress in female ob/ob mice.
PMID:日期:2026-09-16We investigated the effects of aerobic exercise training (ET) on cardiac function, autonomic modulation, and inflammatory and oxidative stress markers in an experimental model of diabetes and obesity …
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5. CARDIOVASCULAR EFFECTS OF INCRETIN RECEPTOR AGONISTS: BEYOND GLYCEMIC CONTROL.
PMID:日期:2026-09-10Incretin-based therapies have evolved from selective GLP-1RA to dual GLP-1/ GIP agonists and unimolecular triple GLP-1/GIP/glucagon receptor agonists. This review examines the cardiovascular effects o…
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6. Respiratory Adverse Effects of IBD Treatments: Mechanisms, Manifestations, and Management Strategies.
PMID:日期:2026-09-10Increasing use of immunomodulators and biologics in IBD has expanded the spectrum of pulmonary complications. To summarize mechanisms, clinical features, and management of druginduced pulmonary toxici…
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7. Endothelin Receptor Antagonism in Sickle Cell Disease: Is the Time Now?
PMID:日期:2026-09-10Sickle cell disease (SCD) is a severe heritable hemoglobinopathy characterized by chronic hemolysis, episodic vaso-occlusion, and progressive multi-organ damage. Although hydroxyurea remains the most …
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8. Beyond Disproportionality: Systematic Prioritization of Actionable Levothyroxine Safety Signals in FAERS.
PMID:日期:2026-09-01Levothyroxine is widely prescribed, yet its real-world safety profile remain unclear. Although disproportionality analysis (DA) can detect potential safety signals, reporting raw findings without syst…
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9. Autophagy -Regulated Myocardial Fibrosis: From Mechanistic Exploration to Therapeutic Prospects.
PMID:日期:2026-08-18Cardiovascular diseases (CVDs) represent a leading cause of global mortality. Myocardial fibrosis (MF), a common pathological hallmark in CVDs, signifies disease progression to severe stages. Its path…
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10. THE ASSOCIATION OF ARTERIAL STIFFNESS WITH THE HIGH INCIDENCE OF CARDIAC ARRHYTHMIAS IN PATIENTS WITH PERIPHERAL ARTERIAL DISEASE.
PMID:日期:2026-08-04The purpose of the study was to identify the incidence and type of arrhythmias and their relationship to the vascular abnormalities in a cross sectional study of 110 patients with peripheral artery di…