Immunity
Immunity(英文缩写 IMMUNITY),ISSN 1074-7613,eISSN 1097-4180 是一本学术期刊。本页汇总该期刊的最新影响因子、分区信息以及最新收录于 PubMed 的文献,帮助您快速了解期刊全貌。
指标来源:jcr_cas_ifqb
期刊简介
暂无简介。
历年影响因子趋势
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Immunity 最新收录文献
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Intercellular adhesion molecule-1-dependent stable interactions between T cells and dendritic cells determine CD8+ T cell memory.
The initiation of cytotoxic immune responses requires the direct interaction between naive CD8+ T lymphocytes and dendritic cells (DCs). Multiphoton imaging in intact lymph nodes (LNs) showed that dur…
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Thymocyte proliferation induced by pre-T cell receptor signaling is maintained through polycomb gene product Bmi-1-mediated Cdkn2a repression.
Thymocytes undergo massive proliferation before T cell receptor (TCR) gene rearrangement, ensuring the diversification of the TCR repertoire. Because activated cells are more susceptible to damage, ce…
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Apoptosis regulators Bim and Fas function concurrently to control autoimmunity and CD8+ T cell contraction.
Throughout most of adult life, lymphocyte number remains constant because of a balance of proliferation and apoptosis. Mutation of Bim, a proapoptotic protein in the intrinsic death pathway, or Fas, a…
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Combined deficiency of proapoptotic regulators Bim and Fas results in the early onset of systemic autoimmunity.
Alterations in the stoichiometric balance between members of Bcl-2 and Fas apoptotic pathway could lead to the pathogenesis of systemic lupus erythematosus (SLE). We showed that patients with SLE disp…
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Apoptosis regulators Fas and Bim cooperate in shutdown of chronic immune responses and prevention of autoimmunity.
Apoptotic death of T lymphocytes is critical for shutdown of immune responses and hemopoietic cell homeostasis. Both death receptor (Fas) activation and mitochondrial apoptosis triggered by the BH3-on…
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The structural dynamics and energetics of an immunodominant T cell receptor are programmed by its Vbeta domain.
Immunodominant and public T cell receptor (TCR) usage is relatively common in many viral diseases yet surprising in the context of the large naive TCR repertoire. We examined the highly conserved Vbet…
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Doubting the TCR coreceptor function of CD8alphaalpha.
"The beginning of wisdom is found in doubting; by doubting we come to question, and by seeking we may come upon the truth." -Pierre Abélard. CD8 is a glycoprotein expressed on hematopoietic cells. Two…
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"The very pulse of the machine": the tuberculous granuloma in motion.
What is happening inside the tuberculous granuloma? In this issue of Immunity, Egen et al. (2008) present live images of tuberculous granulomas of the mouse, demonstrating the influx and incessant wan…
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The importance of prolonged binding to antigen-presenting cells for T cell fate decisions.
How critical is it for T cells to stably arrest on antigen-presenting cells? In this issue of Immunity, Scholer et al. (2008) demonstrate profound effector and memory defects for CD8(+) T cells encoun…
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Fas Bim boom!
New findings by Hughes et al. (2008), Hutcheson et al. (2008), and Weant et al. (2008) highlight the roles of apoptosis regulators Bim and Fas in the contraction phase of T cell responses and reveal c…