ACTA VETERINARIA HUNGARICA匈牙利兽医学报
ACTA VETERINARIA HUNGARICA(英文缩写 ACTA VET HUNG),ISSN 0236-6290,eISSN 1588-2705,中文译名:匈牙利兽医学报 是一本学术期刊。本页汇总该期刊的最新影响因子、分区信息以及最新收录于 PubMed 的文献,帮助您快速了解期刊全貌。
发文量统计区间：2025-09-27 至 2026-09-27，按本站收录文献的发表日期统计。
期刊介绍
历年影响因子趋势
| JCR 数据年份 | 影响因子 | JCR 分区 |
|---|---|---|
| 2021 | 0.959 | Q3 |
| 2022 | 0.900 | Q3 |
| 2023 | 0.700 | Q3 |
| 2024 | 0.800 | Q3 |
| 2025 | 1.000 | Q3 |
ACTA VETERINARIA HUNGARICA 最新收录文献
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1. Contraception of zoo animals using Improvac® in German-speaking countries - A questionnaire survey.
PMID:日期:2026-09-16The aim of this study was to obtain an overview of applied contraceptive methods, with a special focus on the gonadotropin-releasing hormone (GnRH) vaccination with Improvac®, in animals in zoological institutions in German-speaking countries. A survey was prepared inquiring commonly vaccinated species, application intervals and booster vaccinations over the past 11 years and sent to 84 zoological facilities. The questionnaire was answered by the respective veterinarians of 21 zoos (response rate 25%). In the study period, the GnRH vaccine was used in 188 individuals of 42 mammalian species. Bovids were vaccinated the most frequently, followed by giraffes, equids and camelids. Application intervals varied widely between zoos and animal species. The most frequently cited reasons for contraception were population management and breeding exclusion on the recommendation of the EAZA Ex situ Programmes. Undesirable pregnancies during vaccination were observed in 17 individuals (12.1%). Three animals successfully produced offspring after cessation of GnRH vaccination. Most common side effects after the injections were a localised swelling, slight lameness and sexual hyperactivity in some male individuals. It can be concluded that contraception with Improvac® is common in zoological institutions, although no consistent vaccination scheme was identified for most species.
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2. Glycyrrhizic acid increased FMD vaccine potency in a mineral-based adjuvant, but not in an oil-based adjuvant.
PMID:日期:2026-09-16Inactivated FMD vaccine with aluminium hydroxide induces Th2 response. Glycyrrhizin is a triterpenoid saponin extracted from the licorice plant, which has immunomodulatory activities. In this study, two different formulations (oil- and alum-based adjuvants) of FMD vaccines were used to see if glycyrrhizic acid (GZA) has an enhancing effect on the adjuvant, and whether its impact depends on the nature of the co-administered adjuvant or not. Balb/c mice were immunised subcutaneously on days 0, 14, and 28 with 2 μg of inactivated FMD virus formulated in Alum or Montanide ISA206 adjuvant with or without GZA. Two weeks later, IFN-γ, IL-2 and IL-4 cytokines, specific total IgG antibodies, IgG1 and IgG2a isotypes, IgG avidity index and serum neutralisation activity were evaluated. The results indicate that GZA enhanced IFN-γ, IL-2 and IFN-γ/IL-4 levels and specific IgG titre compared to the FMD-Alum group. In addition, FMD-Montanide ISA206-GZA enhanced IFN-γ and IFN-γ/IL-4 ratio, whereas it suppressed the specific IgG titre and the avidity index. Furthermore, serum neutralisation tests showed a significant increase in FMD-Alum-GZA group, while GZA in the Montanide-based vaccine suppressed the serum neutralisation response. These findings suggest that the adjuvant effect of GZA is dependent on the co-administered adjuvant.
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3. Genetic diversity and recombination of NA-PRRSV field strains in Vietnam: Implications for vaccine efficacy.
PMID:日期:2026-09-16Porcine reproductive and respiratory syndrome (PRRS) causes severe reproductive losses in pregnant sows and piglets, resulting in substantial economic impact on the swine industry worldwide. However, due to the significant genetic diversity and rapid evolutionary changes of the pathogen, continuous surveillance and detailed genetic analysis of circulating strains are essential. The current study aimed to evaluate the genetic diversity of the hypervariable (HV) region of non-structural protein 2 (nsp2) among North American PRRSV strains isolated from swine farms in Vietnam. Phylogenetic analysis and multiple sequence alignment were conducted to determine subtype classification and assess genetic variability. A total of 48 field isolates were obtained, of which 12.5% belonged to classical NA-PRRSV, 16.6% to NADC30-like and 70.9% to HP-PRRSV, primarily distributed across sublineages 1.4, 5.1, 8.7 and 8.9. Amino acid comparisons found multiple insertions, deletions and substitutions at various positions within the hypervariable region of nsp2. The study revealed substantial genetic variation in the HV region of nsp2 among NA-PRRSV field strains, largely associated with recombination and immune escape. These findings highlight epidemiological risks to vaccine efficacy and underscore the need for continuous molecular surveillance to support effective PRRSV control in Vietnam.
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4. Immunogenicity and efficacy of NewFluRazi vaccine against Newcastle disease in SPF chickens.
PMID:日期:2026-09-16Newcastle Disease (ND) is a major poultry disease worldwide causing substantial economic losses in the poultry production system. This research aimed to assess efficacy of the NewFluRazi vaccine to in protecting against Newcastle disease. In the study, 90 specific pathogen-free (SPF) chickens, 21 days old, were randomly divided into five groups-four groups were vaccinated while one group remained unvaccinated. At 42 days of age, all birds in the four vaccinated groups and the control group were exposed to a highly virulent genotype VII strain of the virus circulating locally. Hem-agglutination inhibition test was performed against the antigen on day 42 to assess immunogenicity. For pathological analysis, tissue samples were collected on days 3, 5 and 7 post-challenge. Lung, trachea, cecal-tonsil and spleen tissues were collected and analysed using real-time PCR on days 3, 5 and 7 post-challenge to detect the presence of the virus. The findings revealed that antibody titers increased in all groups 21 days' post-vaccination. Antibody levels in the NewFluRazi and the international bivalent groups were higher than in the national bivalent vaccine group with mean titers of 5.2, 5.2, and 5, respectively. Pathological assessment following the challenge showed no significant difference in the mean lesion scores between the groups. Viral gene expression in the tissues was significantly lower in the NewFluRazi vaccine group compared to the international bivalent vaccine group. For instance, on day 5 post-challenge, the mean CT value for the tissues in the NewFluRazi group was 34.12, whereas it was 22.08 in the international bivalent vaccine group. Overall, our results indicate that the NewFluRazi vaccine was more effective than the international bivalent vaccine in reducing viral presence in the target tissues following challenge.
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5. Prevalence and viral load dynamics of PCV-2 and PCV-3 on large Hungarian swine farms.
PMID:日期:2026-09-16Porcine Circovirus 3 (PCV-3) was first identified in 2016 and has since been detected in swine herds worldwide. The aim of this study was to survey the prevalence of PCV-2 and PCV-3 in large Hungarian swine herds. Between July 2020 and April 2022, a total of 1,408 blood samples were collected from 18 large herds and pooled sampling was applied by combining equal amounts from five individuals per pool. PCV-3 positive samples were detected in 94.4% (17/18) of the farms, with an overall apparent prevalence of 30.4% (89/293) in the tested pools. PCV-2 was found in 50.0% (9/18) of the farms, with 14.7% (43/293) of pools testing positive. After correction for imperfect PCR sensitivity and specificity (assumed to be 95%), the corrected prevalence of PCV-3 was 28.2% (83/293) and 10.7% (32/293) for PCV-2, farm-level prevalence estimates remained unchanged. Quantitative PCR analysis revealed that 24.2% of the PCV-3-positive pools had low (Cq > 30), 5.8% medium (28 < Cq < 30) and 1.0% high viral loads (Cq < 28). These results confirm that PCV-3 is widely present in large Hungarian swine farms. The relatively high prevalence, viral load and frequent co-infections raise the possibility of subclinical infections, although the clinical significance of PCV-3 requires further investigation.
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6. Malignant adenomyoepithelioma with papillary arrangement in the mammary papilla of a dog: Case report.
PMID:日期:2026-09-16Mammary gland tumours are the most frequently diagnosed neoplasms in female dogs, involving either the mammary gland parenchyma or the mammary papilla. This is a case report of a malignant adenomyoepithelioma with papillary arrangement in the mammary papilla of a 13-year-old female Lhasa Apso, highlighting the histopathological and immunohistochemical characteristics of the tumour. Grossly, the sample consisted of a exophytic, soft to firm nodule measuring 1.0 × 1.0 cm. On the cut surface, the sample presented an irregular pattern and a cystic cavity. The cut surface of the sentinel lymph node showed a solid and heterogeneous aspect. Histologically, the mammary gland presented a neoplastic proliferation of epithelial and myoepithelial cells in a mostly papillary pattern. Myoepithelial cells exhibited elongated, manly vacuolated cytoplasm, with indistinct boundaries, moderate anisocytosis, anisokaryosis and moderate cellular and nuclear pleomorphism, with seven mitotic figures per 10 high-power fields (i.e., 2.37 mm2). The lymph node presented follicular hyperplasia. Immunohistochemical analysis of the primary tumour revealed neoplastic cells positive for pan-cytokeratin and p63, presented a Ki-67 index of 20% and were negative (score 0) for cyclooxygenase-2. Based on histomorphological and immunophenotypic findings, the mammary tumour was diagnosed as a malignant adenomyoepithelioma with a papillary pattern.
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7. Evaluation of platelet parameters in dogs with uncomplicated pituitary-dependent hyperadrenocorticism.
PMID:日期:2026-09-16Among dogs with hyperadrenocorticism (HAC), thrombocytosis is frequently reported and is considered to be associated with a hypercoagulable state. Substantial and easily accessible haematological evidence such as platelet count (PLT), plateletcrit (PCT), mean platelet volume (MPV) and platelet distribution width (PDW) indicating hypercoagulability may serve as a basis for considering therapeutic management. This study was performed on 22 dogs diagnosed with uncomplicated pituitary-dependent hyperadrenocorticism (PDH). Twelve dogs were assigned to the control group by computer-based randomisations. A series of standard clinical procedures in all dogs, including clinical examination, blood analyses, urinalysis and abdominal ultrasonography were performed. Platelet-related indices such as PLT, PCT, MPV and PDW were also evaluated at the time of admission in all dogs. Dogs were excluded if they had a secondary disease or hypertension (≥160 mmHg). Although no statistical significance was present, PLT, PCT and PDW were higher in PDH dogs compared to healthy controls. In addition, MPV was lower in PDH dogs (P < 0.05). In conclusion, exhausted bone marrow activity associated with the chronicity of HAC may demonstrate lower MPV values in dogs with PDH. Further studies evaluating the relationship between platelet parameters obtained by whole blood samples and PDH dogs are needed.
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8. Dried blood spot-based omega-3 fatty acid status assessment in dogs: The Omega-3 Index concept and its dermatological perspective - Short communication.
PMID:日期:2026-09-16Long-chain omega-3 fatty acids (ω-3 FAs), particularly eicosapentaenoic acid (EPA, C20:5 ω-3) and docosahexaenoic acid (DHA, C22:6 ω-3), are widely used in canine medicine as nutritional adjuncts in chronic inflammatory and degenerative diseases. Blood-based biomarkers, especially erythrocyte fatty acid composition, provide an integrated measure of long-term ω-3 FA exposure and are less susceptible to short-term dietary fluctuations than plasma indices. Within this framework, the Omega-3 Index (O3I) - the sum of 2 prominent long-chain ω3 fatty acids (EPA and DHA) in erythrocyte membranes, expressed as a percentage of total erythrocyte FAs - offers a standardised, biologically anchored metric of ω-3 FA status with potential relevance for clinical evaluation and monitoring. Studies in healthy dogs demonstrate low baseline O3I levels, while dietary supplementation with marine-derived ω-3 FAs reliably increases both circulating plasma concentrations and erythrocyte-based indices of ω-3 FA status. In dogs with chronic diseases such as osteoarthritis, cardiac diseases, and selected gastrointestinal disorders, reduced ω-3 FA status is observed and supplementation results in measurable biochemical changes (lower content of triglyceride and total cholesterol, better antioxidant status, reduced production of prostaglandin E2 and interleukin-6). In contrast, comparable erythrocyte-based data are very limited in canine dermatology. Although species-specific reference ranges and outcome-based targets are not yet established, assessment of ω-3 FA status offers a promising tool for monitoring FA supply, guiding supplementation and supporting individualised clinical nutritional management in canine practice.
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9. Impact of Tilapinevirus tilapiae (TiLV) infection on the composition and functional dynamics of gut microbiota in Nile Tilapia (Oreochromis niloticus) (Linnaeus, 1758).
PMID:日期:2026-09-16Tilapinevirus tilapiae (TiLV) (formerly Tilapia Lake Virus) is a highly prevalent pathogen capable of inducing significant mortality rates in Nile tilapia (Oreochromis niloticus). The alterations induced by Tilapia Lake Virus (TiLV) in the gut microbiota composition, diversity and functional prediction of Nile tilapia have not been thoroughly investigated. This study investigated the gut microbiota of a healthy control group and a TiLV-infected group of Nile tilapia of size 30 ± 2.45g. The alpha diversity of microbiota was hardly affected by TiLV infection, whereas species richness and beta diversity patterns explained the significant differences between control and TiLV-infected groups. The study highlighted a decline in Cetobacterium and an increase in Mycobacterium in the TiLV-infected group. The phyla, including Firmicutes, Actinobacteriota and Proteobacteria, exhibited a significant increase in the TiLV-infected group, while Bacteroidota and Fusobacteriota decreased substantially. The PICRUSt-based functional gene prediction revealed that TiLV infection had considerably changed the KEGG (Kyoto Encyclopaedia of Genes and Genomes) pathways associated with membrane transport, amino acid metabolism, transcription, carbohydrate metabolism, cellular process and signalling in the gut microbiota of Nile tilapia. The results suggest that the infection by TiLV altered the composition and functional pathways in the gut microbiota of Nile tilapia.
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10. Evaluation of the Brix refractometer for diagnosing the failure of transfer of passive immunity in 12-h-old foals.
PMID:日期:2026-09-16Failure of transfer of passive immunity (FTPI) is the most important cause of sepsis and mortality in neonatal foals. This study aimed to evaluate the performance of the digital Brix refractometer for the diagnosis of FTPI in 12-h-old foals. Cross-sectional, diagnostic accuracy study. Jugular blood samples were collected from 124 foals at 12 ± 0.5 h after birth. IgG concentrations were estimated using a digital Brix refractometer and measured using the radial immunodiffusion test (RID). Correlation coefficients were calculated between serum Brix percentages and IgG concentrations. A receiver operating curve (ROC) was created to identify the Brix thresholds for diagnosing FTPI and to calculate the sensitivity (Se) and specificity (Sp) of the tests. Optimum thresholds were selected based on the Youden index. The area under the ROC curve (AUC) was calculated to evaluate the discrimination ability of the Brix refractometer. There was a high correlation (r = 0.72) between the Brix percentages and RID IgG concentrations of the foals at 12 h after birth. The optimum threshold of the digital Brix refractometer to diagnose complete FTPI (IgG of <400 mg*dL-1) was ≤7.5% with 77.8% Se and 76.4% Sp. The optimum Brix threshold to diagnose complete/partial FTPI (IgG of <800 mg*dL-1) was ≤7.8% with 79.5% Se and 78.8% Sp. The Brix refractometer was moderately accurate in differentiating between foals with or without complete/partial FTPI (AUC ranged from 0.7 to 0.9). Alternatively, when FTPI was diagnosed with >90% sensitivity, the Brix threshold was identified as ≤8.4% for both IgG concentrations (Se 92.9% at <400 mg*dL-1; Se 90.0% at <800 mg*dL-1). The digital Brix refractometer detected complete and partial FTPI in 12-h-old foals with a sensitivity below 80%. This constitutes a handicap for the use of Brix refractometry in the horse industry. Future studies should compare the diagnostic accuracy of on-site tests, directly measuring IgG concentrations and refractometry in newborn foals and conduct a cost-benefit analysis of the combined use of these methods.