Reviews of Environmental Contamination and Toxicology环境污染与毒理学评论
Reviews of Environmental Contamination and Toxicology(英文缩写 REV ENVIRON CONTAM T),ISSN 0179-5953,eISSN 2197-6554,中文译名:环境污染与毒理学评论 是一本学术期刊。本页汇总该期刊的最新影响因子、分区信息以及最新收录于 PubMed 的文献,帮助您快速了解期刊全貌。
发文量统计区间：2025-11-01 至 2026-10-31，按本站收录文献的发表日期统计。
期刊介绍
历年影响因子趋势
| JCR 数据年份 | 影响因子 | JCR 分区 |
|---|---|---|
| 2021 | 7.900 | Q1 |
| 2022 | 6.000 | Q1 |
| 2023 | 6.100 | Q1 |
| 2024 | 6.600 | Q1 |
| 2025 | 8.300 | Q1 |
Reviews of Environmental Contamination and Toxicology 最新收录文献
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1. The Epidemiological and Toxicological Intersection of Air Pollution and Dementia.
1. 空气污染与痴呆症的流行病学和毒理学交叉研究PMID:日期:2025-10-10Accumulating evidence indicates that exposure to air pollution can be strongly associated with the development of dementia. However, different components and species of air pollution have been found to have varying associations with incidence of dementia in exposed populations. Among the most broadly studied pollutants in this context are particulate matter (PM), nitrogen dioxide (NO), ozone (O), and sulfur dioxide (SO). Here, we offer a joint toxicological and epidemiological review of the association of each of these well-studied pollutants with dementia, as well as other less-studied pollutants, such as black carbon (BC) and metals (both independently potent components of PM), carbon monoxide (CO), and polyaromatic hydrocarbons (PAHs). Sources and properties of these pollutants are considered in tandem with studies regarding their epidemiological association with dementia and the possible biological basis of these associations. By considering this joint perspective, we identify the pollutants with the greatest association with dementia incidence. Further, we offer a classification of pathological mechanisms and subtypes of dementia associated with exposure to the aforementioned pollutants. Despite variance in exposure assessment, dementia diagnosis and follow-up, and source population, our qualitative review indicates exposure to air pollutants, especially PM and NO, is associated with increased risk and incidence of dementia. Increasing evidence shows exposure to specific pollutants is tied to pathological mechanisms and dementia subtypes, as summarized here. The online version contains supplementary material available at 10.1007/s44169-025-00092-6.
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2. Biomonitoring Xenobiotics in Human Biospecimens: Challenges, Advances, and the Future of Exposome Characterization.
2. 人体生物样本中外源性物质的生物监测：挑战、进展与暴露组表征的未来PMID:日期:2025-06-28Xenobiotics, defined as foreign chemical substances not normally produced by or expected to be present in an organism, are pervasive throughout the human body system. While some xenobiotics have known adverse health effects, the impact of many remains unclear, particularly when considering the potential synergistic or additive effects of chemical mixtures. Human biomonitoring, using biospecimens such as blood, urine, placenta, umbilical cord blood, stool, milk, sweat, saliva, tears, teeth, hair, nails, breath, and cerebrospinal fluid, is a common approach to assess xenobiotic exposure. However, these matrices have inherent limitations in accurately measuring the vast array of chemicals constituting the human chemical exposome-the entirety of chemical exposures an individual experiences over time. This comprehensive review critically analyzes the advantages and limitations of both invasive and noninvasive biospecimens used in human biomonitoring. We outline major classes of detectable xenobiotics in these matrices, compare their qualitative and quantitative feasibility, and discuss challenges in using biospecimens to monitor the internal chemical exposome. The review highlights the importance of integrating complementary external monitoring methods alongside biospecimen analysis, given the short half-lives and trace levels of some xenobiotics in accessible biospecimens. We also discuss emerging technologies and methodologies in biomonitoring, including advanced analytical techniques, wearable sensors, and multi-omics approaches. Additionally, we discuss the ethical, legal, and social implications of biomonitoring and external monitoring. By synthesizing current knowledge and identifying research gaps, this review provides a comprehensive overview of xenobiotics in human biospecimens and outlines future directions for better characterizing the human chemical exposome. These insights are crucial for advancing our understanding of xenobiotic exposures and their health impacts, ultimately informing more effective strategies for disease prevention and intervention.
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3. Correction to: Prioritization of Pesticides for Assessment of Risk to Aquatic Ecosystems in Canada and Identification of Knowledge Gaps.
3. 更正：加拿大水生生态系统风险评估中农药的优先排序及知识差距的识别PMID:日期:2021该文献暂无摘要。
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4. Metalliferous Mining Pollution and Its Impact on Terrestrial and Semi-terrestrial Vertebrates: A Review.
PMID:日期:2021Metalliferous mining, a major source of metals and metalloids, has severe potential environmental impacts. However, the number of papers published in international peer-reviewed journals seems to be low regarding its effects in terrestrial wildlife. To the best of our knowledge, our review is the first on this topic. We used 186 studies published in scientific journals concerning metalliferous mining or mining spill pollution and their effects on terrestrial and semi-terrestrial vertebrates. We identified the working status of the mine complexes studied, the different biomarkers of exposure and effect used, and the studied taxa. Most studies (128) were developed in former mine sites and 46 in active mining areas. Additionally, although several mining accidents have occurred throughout the world, all papers about effects on terrestrial vertebrates from mining spillages were from Aznalcóllar (Spain). We also observed a lack of studies in some countries with a prominent mining industry. Despite >50% of the studies used some biomarker of effect, 42% of them only assessed exposure by measuring metal content in internal tissues or by non-invasive sampling, without considering the effect in their populations. Most studied species were birds and small mammals, with a negligible representation of reptiles and amphibians. The information gathered in this review could be helpful for future studies and protocols on the topic and it facilitates a database with valuable information on risk assessment of metalliferous mining pollution.
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5. Multi-Level Gene Expression in Response to Environmental Stress in Aquatic Invertebrate Chironomids: Potential Applications in Water Quality Monitoring.
PMID:日期:2021In freshwater ecosystems, aquatic invertebrates are influenced continuously by both physical stress and xenobiotics. Chironomids (Diptera; Chironomidae), or non-biting midges, are the most diverse and abundant invertebrates in freshwater habitats. They are a fundamental link in food chains of aquatic ecosystems. Chironomid larvae tolerate stress factors in their environments via various physiological processes. At the molecular level, environmental pollutants induce multi-level gene responses in Chironomus that regulate cellular protection through the activation of defense processes. This paper reviews literature on the transcriptional responses of biomarker genes to environmental stress in chironomids at the molecular level, in studies conducted from 1991 to 2020 (120 selected literatures of 374 results with the keywords "Chironomus and gene expression" by PubMed search tool). According to these studies, transcriptional responses in chironomids vary depending on the type of stress factor and defensive responses associated with antioxidant activity, the endocrine system, detoxification, homeostasis and stress response, energy metabolism, ribosomal machinery, apoptosis, DNA repair, and epigenetics. These data could provide a comprehensive overview of how Chironomus species respond to pollutants in aquatic environments. Furthermore, the transcriptomic data could facilitate the development of genetic tools for water quality and environmental monitoring based on resident chironomid species.
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6. Role of Structural Morphology of Commodity Polymers in Microplastics and Nanoplastics Formation: Fragmentation, Effects and Associated Toxicity in the Aquatic Environment.
PMID:日期:2021With the continued growth in plastic production, its ubiquitous use and insufficient waste management and disposal, the increased levels of plastics in the environment have led to growing ecological concerns. The breakdown of these plastic macromolecules to smaller micro and nanosized particles and their detection in the aerial, aquatic, marine and terrestrial environments has been reviewed extensively, especially for thermoplastics. However, the formation of micro and nanoplastics has typically been explained as a physical abrasion process, largely overlooking the underlying chemical structure-morphology correlations to the degradation mechanisms of the plastics. This is particularly true for the common commodity thermosets. This review focuses on the degradation pathways for the most widely produced commodity thermoplastics and thermosets into microplastics (MP)s and nanoplastics (NP)s, as well as their behaviour and associated toxicity. Special emphasis is placed on NPs, which are associated with greater risks for toxicity compared to MPs, due to their higher surface area to volume ratios. This review also assesses the current state of standardized detection and quantification methods as well as comprehensive regulations for these fragments in the aquatic environment.
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7. Prioritization of Pesticides for Assessment of Risk to Aquatic Ecosystems in Canada and Identification of Knowledge Gaps.
7. 在评估加拿大水生生态系统风险和查明知识差距时优先考虑农药PMID:日期:2021Pesticides can enter aquatic environments via direct application, via overspray or drift during application, or by runoff or leaching from fields during rain events, where they can have unintended effects on non-target aquatic biota. As such, Fisheries and Oceans Canada identified a need to prioritize current-use pesticides based on potential risks towards fish, their prey species, and habitats in Canada. A literature review was conducted to: (1) Identify current-use pesticides of concern for Canadian marine and freshwater environments based on use and environmental presence in Canada, (2) Outline current knowledge on the biological effects of the pesticides of concern, and (3) Identify general data gaps specific to biological effects of pesticides on aquatic species. Prioritization was based upon recent sales data, measured concentrations in Canadian aquatic environments between 2000 and 2020, and inherent toxicity as represented by aquatic guideline values. Prioritization identified 55 pesticides for further research nationally. Based on rank, a sub-group of seven were chosen as the top-priority pesticides, including three herbicides (atrazine, diquat, and S-metolachlor), three insecticides (chlorpyrifos, clothianidin, and permethrin), and one fungicide (chlorothalonil). A number of knowledge gaps became apparent through this process, including gaps in our understanding of sub-lethal toxicity, environmental fate, species sensitivity distributions, and/or surface water concentrations for each of the active ingredients reviewed. More generally, we identified a need for more baseline fish and fish habitat data, ongoing environmental monitoring, development of marine and sediment-toxicity benchmarks, improved study design including sufficiently low method detection limits, and collaboration around accessible data reporting and management.
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8. Review on Health Impacts from Domestic Coal Burning: Emphasis on Endemic Fluorosis in Guizhou Province, Southwest China.
8. 家庭燃煤健康影响综述：以中国西南贵州省地方性氟中毒为重点PMID:日期:2021Endemic fluorosis in Guizhou Province, Southwest China was firstly reported by Lyth in 1946 and was extensively concerned since the early 1980s. Initially, the pathological cause of endemic fluorosis in Guizhou Province was instinctively ascribed to the drinking water. However, increasing evidences pointed that the major exposure route of fluorine for the local residents is via the roasted foodstuffs, especially the roasted pepper and corn. Source of fluorine in roasted foodstuffs was once blamed on the local coal and subsequently imputed to clay mixed in the coal. In fact, both are probably the source. Geogenic fluorine concentration in soil and clay is indeed high in Guizhou Province, but is not likely to be the direct cause for endemic fluorosis. The real culprit for endemic fluorosis in Guizhou Province is the unhealthy lifestyle of the local residents, who usually roasted their foodstuffs using local coal or briquettes (a mixture of coal and clay), resulting in the elevated fluorine in roasted foodstuffs. Nowadays, endemic fluorosis in Guizhou Province has substantially mitigated. Nevertheless, millions of confirmed cases of dental fluorosis remain left. In addition to endemic fluorosis, other health problems associated with domestic coal burning may also exist, because of the enrichment of toxic/harmful elements in the local coal. It is necessary to determine how serious the situation is and find out the possible solution. As people in other developing countries may suffer from similar health issues, same health issues around the world deserve more attention.
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9. In Vivo and In Vitro Toxicity Testing of Cyanobacterial Toxins: A Mini-Review.
9. 蓝藻毒素的体内和体外毒性测试：简要综述PMID:日期:2021Harmful cyanobacterial blooms are increasing and becoming a worldwide concern as many bloom-forming cyanobacterial species can produce toxic metabolites named cyanotoxins. These include microcystins, saxitoxins, anatoxins, nodularins, and cylindrospermopsins, which can adversely affect humans, animals, and the environment. Different methods to assess these classes of compounds in vitro and in vivo include biological, biochemical, molecular, and physicochemical techniques. Furthermore, toxic effects not attributable to known cyanotoxins can be observed when assessing bloom material. In order to determine exposures to cyanotoxins and to monitor compliance with drinking and bathing water guidelines, it is necessary to have reliable and effective methods for the analysis of these compounds. Many relatively simple low-cost methods can be employed to rapidly evaluate the potential hazard. The main objective of this mini-review is to describe the assessment of toxic cyanobacterial samples using in vitro and in vivo bioassays. Newly emerging cyanotoxins, the toxicity of analogs, or the interaction of cyanobacteria and cyanotoxins with other toxicants, among others, still requires bioassay assessment. This review focuses on some biological and biochemical assays (MTT assay, Immunohistochemistry, Micronucleus Assay, Artemia salina assay, Daphnia magna test, Radionuclide recovery, Neutral red cytotoxicity and Comet assay, Enzyme-Linked Immunosorbent Assay (ELISA), Annexin V-FITC assay and Protein Phosphatase Inhibition Assay (PPIA)) for the detection and measurement of cyanotoxins including microcystins, cylindrospermopsins, anatoxin-a, saxitoxins, and nodularins. Although most bioassay analyses often confirm the presence of cyanotoxins at low concentrations, such bioassays can be used to determine whether some strains or blooms of cyanobacteria may produce other, as yet unknown toxic metabolites. This review also aims to identify research needs and data gaps concerning the toxicity assessment of cyanobacteria.
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10. The Toxic Effect of Silver Nanoparticles on Nerve Cells: A Systematic Review and Meta-Analysis.
PMID:日期:2021Despite the increasing use of silver nanoparticles in medical sciences, published studies on their interaction with nerve cells and evaluation of risks are dispersed. This systematic review and meta-analysis could be used to devise safety guidelines for the use of silver nanoparticles in industry and medicine to reduce adverse effects on the CNS.After extensive searches, the full text of 30 related studies was reviewed and data mining completed. Data were analyzed by calculating the mean of different ratios between treated and untreated groups. Linear regression between variables was evaluated by meta-regression. Subgroup analysis was also performed due to heterogeneity.Treatment with silver nanoparticles significantly reduced cell viability (SMD = -1.79%; 95% CI: -2.17 to -1.40; p < 0.0001). Concentration > 0.1 μg/mL could kill neurons, while lower concentration would not (SMD -0.258; 95% CI: -0.821 to 0.305; p = 369). In addition to the concentration, the coating, size of the nanoparticles, and cell type are also factors that influence SNP nerve cell toxicity. Measurement of apoptosis (SMD = 2.21; 95% CI: 1.62 to 2.80; p=0.001) and lactate dehydrogenase release rate (SMD = 0.9; 95% CI: 0.33 to 1.47; p < 0.0001) also confirmed the destructive effect of silver nanoparticles on nerve cells.