XENOBIOTICA

XENOBIOTICA(英文缩写 XENOBIOTICA),ISSN 0049-8254,eISSN 1366-5928 是一本学术期刊。本页汇总该期刊的最新影响因子、分区信息以及最新收录于 PubMed 的文献,帮助您快速了解期刊全貌。

指标来源：jcr_cas_ifqb

历年影响因子趋势

XENOBIOTICA 最新收录文献

1. Role of pharmacodiagnostic of CYP2C9 variants in the optimization of warfarin therapy in Malaysia: a 6-month follow-up study.
   H Ngow, L K Teh, I M Langmia, W L Lee, R Harun, R Ismail
   Xenobiotica; the fate of foreign compounds in biological systems 2008 IF: 1.50 Q4 PMID: 18570163

   1. A retrospective study was conducted to explore the importance of CYP2C9 genotyping for the initiation and maintenance therapy of warfarin in clinical practice. A total of 191 patients on warfarin t…

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2. Pre-clinical pharmacokinetics of UK-453,061, a novel non-nucleoside reverse transcriptase inhibitor (NNRTI), and use of in silico physiologically based prediction tools to predict the oral pharmacokinetics of UK-453,061 in man.
   G Allan, J Davis, M Dickins, I Gardner, T Jenkins, H Jones
   Xenobiotica; the fate of foreign compounds in biological systems 2008 IF: 1.50 Q4 PMID: 18570162

   1. UK-453,061 is a novel second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI). Following intravenous bolus administration of UK-453,061 in male rat and infusion administration in d…

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3. Differences in the total body clearance of lead compounds in the rat and mouse: impact on pharmacokinetic screening strategy.
   T A McIntyre, C Han, H Xiang, R Bambal, C B Davis
   Xenobiotica; the fate of foreign compounds in biological systems 2008 IF: 1.50 Q4 PMID: 18570161

   1. The in vivo clearance (CL) for 498 compounds representing more than 40 lead optimization programmes were compared in the rat and mouse. 2. A total of 278 of the compounds had similar CL values in r…

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4. Phase II enzyme induction by alpha-lipoic acid through phosphatidylinositol 3-kinase-dependent C/EBPs activation.
   S H Ki, S G Kim
   Xenobiotica; the fate of foreign compounds in biological systems 2008 IF: 1.50 Q4 PMID: 18570160

   1. alpha-Lipoic acid (alpha-LA) activates antioxidant pathways and exerts insulin-like actions via phosphatidylinositol 3-kinase (PI3K), and previous studies from the authors' laboratory support the e…

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5. Effect of butylated hydroxytoluene, curcumin, propyl gallate and thiabendazole on cytochrome P450 forms in cultured human hepatocytes.
   R J Price, M P Scott, A M Giddings, D G Walters, R H Stierum, C Meredith
   Xenobiotica; the fate of foreign compounds in biological systems 2008 IF: 1.50 Q4 PMID: 18570159

   1. The objective of this study was to investigate the effects of four food chemicals, namely butylated hydroxytoluene (BHT), curcumin (CC), propyl gallate (PG) and thiabendazole (TB), on cytochrome P4…

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6. Inhibition of P-glycoprotein in Caco-2 cells: effects of herbal remedies frequently used by cancer patients.
   S Engdal, O G Nilsen
   Xenobiotica; the fate of foreign compounds in biological systems 2008 IF: 1.50 Q4 PMID: 18570158

   1. The herbal products Natto K2, Agaricus, mistletoe, noni juice, green tea and garlic were investigated for in vitro inhibitory potential on P-glycoprotein (P-gp)-mediated transport of digoxin (30 nM…

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7. Metabolism of prazosin in rat and characterization of metabolites in plasma, urine, faeces, brain and bile using liquid chromatography/mass spectrometry (LC/MS).
   J C L Erve, S C Vashishtha, O Ojewoye, A Adedoyin, R Espina, W Demaio
   Xenobiotica; the fate of foreign compounds in biological systems 2008 IF: 1.50 Q4 PMID: 18421626

   1. Prazosin, 2-[4-(2-furanoyl)-piperazin-1-yl]-4-amino-6,7-dimethoxyquinazoline, is an antihypertensive agent that has been used safely since 1976 and is currently being investigated for the treatment…

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8. Comparative evaluation of absorption, distribution, and excretion of YM758, a novel If channel inhibitor, between albino and non-albino rats.
   K-I Umehara, K Seya, T Sonoda, E Nakamura, K Noguchi, T Usui
   Xenobiotica; the fate of foreign compounds in biological systems 2008 IF: 1.50 Q4 PMID: 18421625

   1. YM758 is a novel If channel inhibitor for the treatment of stable angina and atrial fibrillation. The absorption, distribution, and excretion of YM758 have been investigated in albino and non-albin…

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9. Pharmacokinetics and metabolism of KW-4490, a selective phosphodiesterase 4 inhibitor: difference in excretion of KW-4490 and acylglucuronide metabolites between rats and cynomolgus monkeys.
   K Fujita, H Kodaira, T Kuwabara, H Kobayashi
   Xenobiotica; the fate of foreign compounds in biological systems 2008 IF: 1.50 Q4 PMID: 18421624

   1. The pharmacokinetics and metabolism of KW-4490, a selective phosphodiesterase 4 inhibitor, were investigated in rats and monkeys. After oral administration, KW-4490 was rapidly absorbed, and then i…

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10. In vitro drug-drug interaction studies with febuxostat, a novel non-purine selective inhibitor of xanthine oxidase: plasma protein binding, identification of metabolic enzymes and cytochrome P450 inhibition.
    M Mukoyoshi, S Nishimura, S Hoshide, S Umeda, M Kanou, K Taniguchi
    Xenobiotica; the fate of foreign compounds in biological systems 2008 IF: 1.50 Q4 PMID: 18421623

    1. The potential for drug-drug interactions with febuxostat was examined in the following three in vitro systems: the characteristics of the binding of febuxostat to human plasma proteins; identificat…

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