JOURNAL OF BIOLOGICAL CHEMISTRY
JOURNAL OF BIOLOGICAL CHEMISTRY(英文缩写 J BIOL CHEM),ISSN 0021-9258,eISSN 1083-351X 是一本学术期刊。本页汇总该期刊的最新影响因子、分区信息以及最新收录于 PubMed 的文献,帮助您快速了解期刊全貌。
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JOURNAL OF BIOLOGICAL CHEMISTRY 最新收录文献
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Episomal high copy number maintenance of hairpin-capped DNA bearing a replication initiation region in human cells.
We previously found that a plasmid bearing a replication initiation region efficiently initiates gene amplification in mammalian cells and that it generates extrachromosomal double minutes and/or chro…
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Physical interactions between Mcm10, DNA, and DNA polymerase alpha.
Mcm10 is an essential eukaryotic protein required for the initiation and elongation phases of chromosomal replication. Specifically, Mcm10 is required for the association of several replication protei…
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Dynamin2 GTPase and cortactin remodel actin filaments.
The large GTPase dynamin, best known for its activities that remodel membranes during endocytosis, also regulates F-actin-rich structures, including podosomes, phagocytic cups, actin comet tails, subc…
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Biglycan, a danger signal that activates the NLRP3 inflammasome via toll-like and P2X receptors.
The role of endogenous inducers of inflammation is poorly understood. To produce the proinflammatory master cytokine interleukin (IL)-1beta, macrophages need double stimulation with ligands to both To…
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A unitary anesthetic binding site at high resolution.
Propofol is the most widely used injectable general anesthetic. Its targets include ligand-gated ion channels such as the GABA(A) receptor, but such receptor-channel complexes remain challenging to st…
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Phosphorylated intrinsically disordered region of FACT masks its nucleosomal DNA binding elements.
FACT is a heterodimer of SPT16 and SSRP1, which each contain several conserved regions in the primary structure. The interaction of FACT with nucleosomes induces chromatin remodeling through the combi…
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Regulation of Rad51 recombinase presynaptic filament assembly via interactions with the Rad52 mediator and the Srs2 anti-recombinase.
Homologous recombination represents an important means for the error-free elimination of DNA double-strand breaks and other deleterious DNA lesions from chromosomes. The Rad51 recombinase, a member of…
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Distinct structures of scrapie prion protein (PrPSc)-seeded versus spontaneous recombinant prion protein fibrils revealed by hydrogen/deuterium exchange.
The detailed structures of prion disease-associated, partially protease-resistant forms of prion protein (e.g. PrP(Sc)) are largely unknown. PrP(Sc) appears to propagate itself by autocatalyzing the c…
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Kinetic and cellular characterization of novel inhibitors of S-nitrosoglutathione reductase.
S-Nitrosoglutathione reductase (GSNOR) is an alcohol dehydrogenase involved in the regulation of S-nitrosothiols (SNOs) in vivo. Knock-out studies in mice have shown that GSNOR regulates the smooth mu…
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MyD88 adapter-like (Mal)/TIRAP interaction with TRAF6 is critical for TLR2- and TLR4-mediated NF-kappaB proinflammatory responses.
Toll/interleukin-1 (TIR)receptor-containing adapters are critical in orchestrating the different signal transduction pathways following Toll-like receptor (TLR) activation. MyD88 adapter-like (Mal), a…